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L'accesso al farmaco

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Book Series: Memorie del Dipartimento di Giurisprudenza - Università di Torino ISBN: 9788867056187 Year: Pages: 179 Language: Italian
Publisher: Ledizioni
Subject: Therapeutics
Added to DOAB on : 2017-07-26 15:19:19
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“Il farmaco è un bene di rilevanza giuridica sia in quanto strumentale alla tutela della salute sia in quanto possibile oggetto di rapporti economici. Si comprende pertanto come la disciplina del farmaco si collochi al crocevia di differenti interessi e come il rapporto tra questo bene e il suo diritto possa declinarsi attraverso molteplici prospettive”. (Dal testo)

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Acupuncture – Basic Research and Clinical Application

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ISBN: 9783038972341 9783038972358 Year: Pages: 170 DOI: 10.3390/books978-3-03897-235-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2018-10-09 11:13:34
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This book focuses on the investigation, development, and modernization of acupuncture in basic research settings as well as in clinical applications. The book contains 13 chapters reporting the latest evidence-based results of acupuncture research and exploring acupuncture in general. Altogether, 44 authors from all over the world contributed to this book.

Advanced Technology for Delivering Therapeutics

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ISBN: 9789535131212 9789535131229 Year: Pages: 184 DOI: 10.5772/62564 Language: English
Publisher: IntechOpen
Subject: Therapeutics
Added to DOAB on : 2019-10-03 07:51:50

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The goal of any novel drug delivery system is to provide therapeutic benefits to the patients by increasing duration of drug action, reducing dosing frequency, and controlling drug release rate at the target site, thereby reducing unwanted side effects. Advanced Technology for Delivering Therapeutics is a reference book that covers recent developments in the field of drug delivery science and technology. The purpose of this book is to bring together descriptions of some selective technologies including new and promising nanotechnology currently being investigated for drug delivery applications. This book is a useful source of information for graduate and post-graduate students of pharmacy and biomedical science; pharmaceutical & other researchers involved in designing newer drug delivery systems both in academia and industry.

Advances in Marine Chitin and Chitosan

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ISBN: 9783038421306 9783038421290 Year: Pages: XIV, 470 DOI: 10.3390/books978-3-03842-129-0 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Therapeutics
Added to DOAB on : 2016-05-20 15:15:59
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Recently, biomass-based polymers from renewable resources have received increasing focus owing to the depletion of petroleum resources. Natural polysaccharides such as cellulose, hemicellulose, and starch are among the candidates from natural resources for biomass polysaccharide products including bioplastics. Although several kinds of neutral or anionic polysaccharides such as chitin, alginic acid, hyaluronic acid, heparin, and chondroitin sulfate exist in nature, natural cationic polysaccharides are quite limited. Chitin is second only to cellulose as the most natural abundant polysaccharide in the world. Chitosan, the product from the N-deacetylatation of chitin, appears to be the only natural cationic polysaccharide. Therefore, chitin and chitosan due to their unique properties are expected to continue to offer a vast number of possible applications for not only chemical or industrial use, but also biomedicine. The research history on chitins, one of the most major and abundant natural polysaccharides on earth, started around 1970. Since the 1980s, chitin and chitosan research (including D-glucosamine, N-acetyl-D-glucosamine, and their oligomers) has progressed significantly over several stages in both fundamental research and industrial fields.

Advances in Micro-Bioreactor Design for Organ Cell Studies

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ISBN: 9783038972334 9783038972327 Year: Pages: 168 DOI: 10.3390/books978-3-03897-232-7 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Therapeutics
Added to DOAB on : 2018-12-06 11:44:20
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Micro-bioreactors offer unique opportunities to study biological systems under fluidic conditions. The concept of micro-bioreactors suggests that biological reaction conditions on a large scale can be scaled down to micro-volumes while maintaining performance and functionality. Models and operation principles can be simulated at a smaller scale, either by scaling down organs in the human body, or using bioreactors for the production of biologics. This book highlights these issues with a strong focus on new engineering design. The initial chapters cover the conceptual design of microbioreactors and organ-on-chips, and the role of microbioreactors in tissue engineering for clinical and therapeutic targets. Two chapters are dedicated to microbioreactors for implementing tumor models. Other chapters discuss three-dimensional models for hepatic and cardiac cells for toxicity testing and drug evaluation. Finally, the design of organ chips for cartilage scaffolds and the integration of sensors are covered in separate chapters. We believe the book will have substantial value for researchers active in bioreactor engineering, drug development and cell physiology, as well as readers interested in these topics.

Advances in Prevention of Foodborne Pathogens of Public Health Concern during Manufacturing

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ISBN: 9783039219322 / 9783039219339 Year: Pages: 168 DOI: 10.3390/books978-3-03921-933-9 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2019-12-09 11:49:16
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According to a report from the U.S. Centers for Disease Control and Prevention (CDC), achieving safe and healthier foods was one of the top ten achievements of public health in the 20th century. However, considerable persisting challenges currently exist in developed nations and developing economies for further assuring the safety and security of the food supplies. According to CDC estimates, as many as 3000 American adults, as an example, and based on a recent epidemiological estimate of the World Health Organization, around 420,000 individuals around the globe, lose their lives annually due to foodborne diseases. This emphasizes the need for innovative and emerging interventions, for further prevention or mitigation of the risk of foodborne microbial pathogens during food processing and manufacturing. The current publication discusses recent advancements and progress in the elimination and decontamination of microbial pathogens during various stages of manufacturing and production. Special emphasis is placed on hurdle validation studies, investigating decontamination of non-typhoidal Salmonella enterica serovars, various serogroups of Shiga toxin-producing Escherichia coli, public health-significant serotypes of Listeria monocytogenes, and pathogenic species of Cronobacter.

Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae?

Authors: --- ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889454822 Year: Pages: 245 DOI: 10.3389/978-2-88945-482-2 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Therapeutics --- Medicine (General) --- Oncology
Added to DOAB on : 2019-01-23 14:53:42
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Advances in anti-cancer chemotherapy over recent years have led to improved efficacy in curing or controlling many cancers. Some chemotherapy-related side-effects are well recognized and include: nausea, vomiting, bone marrow suppression, peripheral neuropathy, cardiac and skeletal muscle dysfunction and renal impairment. However, it is becoming clearer that some chemotherapy-related adverse effects may persist even in long term cancer survivors. Problems such as cognitive, cardiovascular and gastrointestinal dysfunction, and neuropathy may lead to substantial long term morbidity. Despite improvements in treatments to counteract acute chemotherapy-induced adverse effects, they are often incompletely effective. Furthermore, counter-measures for some acute side-effects and many potential longer term sequelae of anti-cancer chemotherapy have not been developed. Thus, new insights into prevalence and mechanisms of cancer chemotherapy-related side effects are needed and new approaches to improving tolerance and reduce sequelae of cancer chemotherapy are urgently needed. The present Research Topic focuses on adverse effects and sequelae of chemotherapy and strategies to counteract them.

AML in the Molecular Age: From Biology to Clinical Management

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ISBN: 9783038972808 9783038972815 Year: Pages: 208 DOI: 10.3390/books978-3-03897-281-5 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2018-10-12 12:12:38
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We appreciate your willingness to contribute an article to the upcoming Special Issue of the Journal of Clinical Medicine, which will focus on “AML in the Molecular Age: From Biology to Clinical Management”. In this Special Issue, we aim to discuss important scientific and clinical ongoing activities in AML. Scientific subjects will include articles concerning the molecular abnormalities, epigenetic mechanisms of disease/therapy as well as the role of the immune system in AML. Very interesting and uncommon subjects will include discussions of extramedullary disease and evaluations of the central nervous system by various imaging techniques. Experts will describe the role of hypomethylating agents in the management of AML and currently emerging and promising investigational therapies. Specifics of treament of pediatric and younger patients with AML. Clinical success relies greatly on supportive therapy, and we will discuss supportive therapy, including infection prophylaxis. Allogeneic hematopoietic stem cell transplantation remains the most effective measure for curing aggressive AML, and a variety of topics will be considered: donor selection, age of recipient, which has been increasing seemingly without limit; therefore, recipient/donor assessments are more important than ever in the aging population. Alternative donor use (e.g., cord blood and haploidentical individuals) has been increasing dramatically; when and who should be considered, what is being investigated? With significant changes occurring with respect to both donors and recipients, the pros and cons of using of anti-thymocyte globulin use in conditioning regimens will be also described.

Anticoagulant Drugs

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ISBN: 9781789236224 9781789236231 Year: Pages: 120 DOI: 10.5772/intechopen.70971 Language: English
Publisher: IntechOpen
Subject: Therapeutics
Added to DOAB on : 2019-10-03 07:51:51

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Anticoagulant drugs are among the most frequently prescribed drugs in everyday clinical practice. In the past decades, several new direct oral anticoagulants were developed that changed the anticoagulant therapy landscape considerably. This book provides an extensive overview of all the known anticoagulants that can be useful for studying different aspects of the haemostatic system or as a starting point for new drug development. It is also a valuable tool for clinicians providing a description of the mode of action and management of therapy for anticoagulant drugs used in everyday clinical practice in different clinical settings, including direct oral anticoagulants dabigatran, rivaroxaban, apixaban and edoxaban.

Biological Activities and Action Mechanisms of Licorice Ingredients

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ISBN: 9789535131199 9789535131205 Year: Pages: 174 DOI: 10.5772/64119 Language: English
Publisher: IntechOpen
Subject: Therapeutics
Added to DOAB on : 2019-10-03 07:51:50

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Licorice extracts are used as additive to many Kampo medicines to alleviate pain and inflammation. With rapid progress of analytical methodology, its action mechanism is being elucidated. This book is composed of three sections. Section 1 introduces licorice as alternative medicine, its application in the industry, and the trading/market prospects between Japan and China. Section 2 summarizes the purification/identification steps of licorice ingredients and their antioxidant, antimicrobial, PPAR-? ligand-binding, antitumor, antiviral, and in vitro fertilization activities. Section 3 proposes the possible molecular mechanism by which licorice ingredients induce anti-inflammatory, antifibrosis, antihepatitis, and antileishmanial activity. All chapters are written by experts of natural sciences and economics and will surely give new insights into alternative medicines to students, clinicians, teachers, and researchers.

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