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Nutrients Intake and Hypertension

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ISBN: 9783039286621 / 9783039286638 Year: Pages: 242 DOI: 10.3390/books978-3-03928-663-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Nutrition and Food Sciences
Added to DOAB on : 2020-06-09 16:38:57
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Abstract

Hypertension is a major health problem worldwide, increasing cardiovascular (CV) risk and mortality. Together with pharmacological treatments, non-pharmacological approaches, such as nutrient intake modifications, play an important role in optimizing treatment. A link has been demonstrated between hypertension and body weight as well as dietary habits. The aim of this Special Issue is to improve the understanding of the relationships between some nutrients and hypertension, and of the effects of different dietary approaches on hypertension regulation from different points of view.

AMP-Activated Protein Kinase Signalling

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ISBN: 9783038976622 Year: Pages: 452 DOI: 10.3390/books978-3-03897-663-9 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2019-03-21 14:08:22
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Starting from a kinase of interest, AMP-activated protein kinase (AMPK) has gone far beyond an average biomolecule. Being expressed in all mammalian cell types and probably having a counterpart in every eukaryotic cell, AMPK has attracted interest in virtually all areas of biological research. Structural and biophysical insights have greatly contributed to a molecular understanding of this kinase. From good old protein biochemistry to modern approaches, such as systems biology and advanced microscopy, all disciplines have provided important information. Thus, multiple links to cellular events and subcellular localizations have been established. Moreover, the crucial involvement of AMPK in human health and disease has been evidenced. AMPK accordingly has moved from an interesting enzyme to a pharmacological target. However, despite our extensive current knowledge about AMPK, the growing community is busier than ever. This book provides a snapshot of recent and current AMPK research with an emphasis on work providing molecular insight, including but not limited to novel physiological and pathological functions, or regulatory mechanisms. Up-to-date reviews and research articles are included.

Keywords

exercise --- glucose uptake --- AMP-activated protein kinase --- TBC1D4 --- AS160 --- AMP-activated protein kinase --- developmental origins of health and disease (DOHaD) --- hypertension --- kidney disease --- nutrient-sensing signals --- oxidative stress --- renin-angiotensin system --- AMPK --- autophagy --- co-expression --- microarrays --- 3T3-L1 --- adipocyte --- differentiation --- AMPK --- tight junctions --- epithelial cells --- ZO-1 --- par complex --- MDCK --- nectin-afadin --- adherent junctions --- TAK1 --- AMPK --- phosphorylation --- AMPK kinase --- endothelial nitric-oxide synthase --- vasodilation --- phenylephrine --- vasoconstriction --- endothelial cells --- ionomycin --- AMPK --- liver --- lipid metabolism --- fatty acid oxidation --- indirect calorimetry --- atrophy --- regrowth --- sirtuin 1 (SIRT1) --- peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?) --- heat shock protein --- fiber-type --- AMPK --- monocytes --- macrophages --- differentiation --- autophagy --- AML --- MDS --- CML --- CMML --- pregnancy --- catechol-O-methyltransferase --- 2-methoxyestradiol --- preeclampsia --- gestational diabetes mellitus --- AMPK --- IL-1? --- NLRP3 --- nutrition --- dietary fatty acids --- metabolic-inflammation --- nutrigenomics --- AMPK --- LKB1 --- autophagy --- proteasome --- hypertrophy --- atrophy --- skeletal muscle --- AICAR --- mTOR --- protein synthesis --- AMPK --- epigenetics --- chromatin remodeling --- histone modification --- DNA methylation --- medulloblastoma --- sonic hedgehog --- AMPK --- AMP-activated protein kinase (AMPK) --- spermatozoa --- motility --- mitochondria --- membranes --- signaling --- stress --- assisted reproduction techniques --- AMP-activated protein kinase --- epigenetics --- protein acetylation --- KATs --- HDACs --- acetyl-CoA --- NAD+ --- AMP-activated protein kinase --- glycogen --- exercise --- metabolism --- cellular energy sensing --- energy utilization --- liver --- skeletal muscle --- metabolic disease --- glycogen storage disease --- resveratrol --- AMPK --- hepatocyte --- liver --- steatosis --- transporter --- carrier --- pump --- membrane --- energy deficiency --- AMPK --- infection --- mycobacteria --- host defense --- energy metabolism --- AMPK --- activation loop --- AID --- ?-linker --- ?-linker --- CBS --- LKB1 --- CaMKK2 --- ?RIM --- hypothalamus --- adenosine monophosphate-activated protein kinase --- adipose tissue --- food intake --- adaptive thermogenesis --- beiging --- AMPK --- HDAC4/5 --- p70S6K --- MyHC I(?), motor endplate remodeling --- soleus muscle --- mechanical unloading --- hindlimb suspension --- AMPK --- synaptic activation --- PKA --- CREB --- soluble Adenylyl cyclase --- Immediate early genes --- transcription --- AMPK --- autophagy --- metabolism --- mTOR --- ULK --- AMP-activated protein kinase --- protein kinase B --- Akt --- insulin signalling --- A769662 --- endothelial function --- n/a

Human Health Engineering

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ISBN: 9783039284085 9783039284092 Year: Pages: 428 DOI: 10.3390/books978-3-03928-409-2 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2020-04-07 23:07:09
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In this Special Issue on human health engineering, we invited submissions exploring recent contributions to the field of human health engineering, which is the technology used for monitoring the physical or mental health status of individuals in a variety of applications. Contributions focused on sensors, wearable hardware, algorithms, or integrated monitoring systems. We organized the different papers according to their contributions to the main aspects of the monitoring and control engineering scheme applied to human health applications, including papers focusing on measuring/sensing physiological variables, contributions describing research on the modelling of biological signals, papers highlighting health monitoring applications, and finally examples of control applications for human health. In comparison to biomedical engineering, the field of human health engineering also covers applications on healthy humans (e.g., sports, sleep, and stress) and thus not only contributes to develop technology for curing patients or supporting chronically ill people, but also more generally for disease prevention and optimizing human well-being.

Keywords

artefact correction --- head-shaped phantom --- spherical phantom --- gradient artefact --- simultaneous EEG–fMRI --- calcaneal spur --- pain minimum compressive pressure --- contour of shoe insole --- insole foot area --- health information --- interface formats --- older adults --- wearable devices --- usability --- emotional reaction --- ADHD --- screening --- machine learning --- SVM --- children --- novel --- nomophobia --- anxiety --- smartphone --- internet --- cyberaddiction --- new technologies --- chronic obstructive pulmonary disease --- COPD --- oxygen uptake --- VO2 --- kinetics --- exercise testing --- rehabilitation robotics --- soft walking assistive robot --- long-term effect --- gait characteristics --- elderly person --- blood pressure estimation --- photoplethysmogram --- pulse wave --- pulse oximeter --- wearable device --- Kano-TRIZ design theory --- quality function deployment --- four-wheeled rollator --- model predictive control --- orthosis control --- muscle modeling --- arm --- Hill muscle --- swarm optimization --- pneumatic artificial muscle --- sliding mode control --- fractional calculus --- antagonistic actuator --- weight loss --- mHealth --- dynamic model --- adaptive control --- spirometry --- airflow limitation --- airway resistance --- specific airway conductance --- COPD --- body-plethysmography --- forced expiration --- alveolar pressure --- emphysema --- computed tomography --- air-trapping --- thermal comfort --- bicycle helmet --- smart wearables --- adaptive model --- streaming data --- thermal sensation --- adaptive model --- personalized model --- machine leaning --- support-vector-machine --- adaptive control --- streaming algorithm --- thermoregulation --- homeostasis --- cold-induced-vasodilation --- cold-induced-vasoconstriction --- control system --- dynamic modelling --- powered mobility --- dyskinetic cerebral palsy --- dystonia --- choreoathetosis --- mobility scale --- movement disorder --- children --- youth --- reliability --- validity --- feature engineering --- intensive care unit --- mortality prediction --- hard-margin support vector machines --- driver drowsiness --- thermoregulation --- distal skin temperature --- decision tree --- heart model --- Van der Pol --- FitzHugh–Nagumo --- relaxation oscillator --- electrocardiographic signal --- bicycle helmets --- thermal manikin --- convective and evaporative heat loss --- zonal performance characteristics --- freestyle skiing aerials --- knee joint --- ligament --- finite element simulation --- lifting technique --- stoop --- squat --- work-related musculoskeletal disorders --- musculoskeletal modeling --- spine --- shoulder --- back loading --- harmonization --- meta-analysis --- missing data --- multiple imputations --- information technology --- remoteness --- cohort studies --- control parameter reference --- stance assistance --- magnetorheological brake --- body mass index --- walking speed --- ankle torque --- ankle angular velocity --- n/a

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