Search results: Found 4

Listing 1 - 4 of 4
Sort by
The Identification of the Genetic Components of Autism Spectrum Disorders 2017

Author:
ISBN: 9783038425205 9783038425212 Year: Pages: X, 462 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology
Added to DOAB on : 2017-10-27 12:54:46
License:

Loading...
Export citation

Choose an application

Abstract

This textbook is dedicated to the study of genetic factors contributing to autism and includes a collection of original research and review articles related to this topic. Autism spectrum disorders (ASD) include a collection of neurodevelopmental disorders characterized by three recognized behavioral domains involving difficulties in communication, social interaction and repetitive behavior. ASD affects 1 to 2 percent of children and is on the increase worldwide. Significant genetic contributions and mechanisms underlie the causation of ASD. Advances in genetic technology and better awareness have led to a diagnosis of 50 to 70 percent of individuals with ASD primarily due to chromosomal abnormalities, submicroscopic deletions or duplications now identified with high-resolution microarray analysis, next-generation DNA (exome) sequencing of gene variants or mutations, recognized single gene disorders or metabolic disturbances. Through discovery by searching genomic databases and peer-reviewed research articles, nearly 800 genes have been identified to contribute to ASD. Highlights in the field of autism research, discovery and identification of genetic components with characterization will be addressed. Furthermore, reviews of current understanding of the causes and diagnostic approaches for ASD and related syndromes will be presented along with discussion of psychiatric/behavior comorbidities and related features, environmental risk factors, parental attitudes and treatment.

Catalyzed Mizoroki–Heck Reaction or C–H activation

Author:
ISBN: 9783039281381 9783039281398 Year: Pages: 182 DOI: 10.3390/books978-3-03928-139-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology --- Science (General)
Added to DOAB on : 2020-04-07 23:07:08
License:

Loading...
Export citation

Choose an application

Abstract

In the last few decades, research on the elaboration by palladium-catalytic processes of C-C bonds or the activation of C–H bonds has increased considerably. Yet there is still room for much improvement in terms of selectivity, or enantioselectivity, via the development of new ligands or the study of the catalytic effect of other metals to carry out the same chemical transformations. In addition, the attention paid to environmentally friendly methods in terms of the quantities of catalysts, ligands, and solvents is currently indispensable. The Mizoroki-Heck reaction is one of these important catalytic methods which generates C-C bonds in organic synthesis and is also possible by C-H activation. This book, titled “Catalyzed Mizoroki-Heck Reaction or C-H activation” focuses on new advances in the formation of C-C bonds or new C-H activation methods. It contains original research papers and short reviews on the synthesis of biologically active compounds using these catalytic processes, the identification of new catalysts, of new conditions allowing selectivity or enantioselectivity, the activity and stability of catalyst under turnover conditions, and all improvements in catalytic processes.

Review of Invertebrate Biological Control Agents Introduced into Europe

Authors: ---
ISBN: 9781786390790; 9781786390806; 9781786390813 Year: Pages: 194 DOI: 10.1079/9781786390790.0000 Language: English
Publisher: CABI
Subject: Agriculture (General) --- Plant Sciences
Added to DOAB on : 2020-10-16 16:28:31
License:

Loading...
Export citation

Choose an application

Abstract

This review provides an overview of all documented releases of exotic (non-European) invertebrate biological control agents (IBCAs) into the environment in Europe and summarizes key information on the target species as well as on the biological control agent released. It is an update of A Review of Biological Control in Western and Southern Europe edited by Greathead (1976) and covers the period from 1897, when the beetle Rodolia cardinalis was introduced into Portugal against the invasive cottony cushion scale, Icerya purchasi, until the end of 2009. This review is based largely on the BIOCAT database (Greathead and Greathead 1992), which contains records of the introduction of insect natural enemies, namely parasitoids and predators, for the control of insect pests worldwide. This review may not provide the complete list of BC agents introduced into Europe. Nevertheless, the report includes a vast majority of the introductions, and hence provides a representative picture of the history of releases of exotic BC agents into the environment in Europe.

Nutrition and Eye Health

Authors: ---
ISBN: 9783039219902 9783039219919 Year: Pages: 242 DOI: 10.3390/books978-3-03921-991-9 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology --- Science (General)
Added to DOAB on : 2020-01-30 16:39:46
License:

Loading...
Export citation

Choose an application

Abstract

Blindness and visual impairment impact significantly on an individual’s physical and mental well-being. Loss of vision is a global health problem, with approximately 250 million of the world’s population currently living with vision loss, of which 36 million are classified as blind. Visual impairment is more frequent in the elderly, with cataract and age-related macular degeneration (AMD) accounting for over 50% of cases globally. Oxidative stress has been strongly implicated in the pathogenesis of both conditions, and consequently the role of nutritional factors, in particular carotenoids and micronutrient antioxidants, have been investigated as possible preventative or therapeutic strategies. Dry eye syndrome (DES) is one of the most common ophthalmic conditions in the world. DES occurs where the eye does not produce enough tears and/or the tears evaporate too quicklyleading to discomfort and varying degrees of visual disturbance. There has recently been a great deal of interest in the potential for oral or topical supplementation with essential fatty acids (EFAs), specifically omega-3 and omega-6 fatty acids, as an adjunct to conventional treatments for DES. The objective of this Special Issue on ‘Nutrition and Eye Health’ is to publish papers describing the role of nutrition in maintaining eye health and the use of nutritional interventions to prevent or treat ocular disease. A particular (but not exclusive) emphasis will be on papers (reviews and/or clinical or experimental studies) relating to cataract, AMD and DES.

Keywords

lutein --- RR-zeaxanthin --- mesozeaxanthin (RS zeaxanthin) --- light damage --- photoreceptor degeneration --- oxidative stress --- endoplasmic reticulum stress --- electroretinography --- advanced glycation end products --- chyrsin --- diabetic retinopathy --- endoplasmic reticulum --- retinal pigment epithelium --- visual cycle --- cataract --- phytoconstituents --- lens --- preclinical models --- drug discovery --- age-related macular degeneration --- gut-retina axis --- gut microbiota --- dietary habits --- micronutrients --- fish oil --- omega-3 polyunsaturated fatty acids --- personalised medicine --- Lactobacillus paracasei KW3110 --- retina --- light --- macrophage --- saffron --- Crocus Sativus L. --- crocin --- crocetin --- supplements --- anti-oxidant --- anti-inflammatory --- AMD --- diabetes --- glaucoma --- retina --- oxidative stress --- inflammation --- microvascular lesions --- neoangiogenesis --- polyphenols --- flavonoids --- carotenoids --- saponins --- rosmarinic acid --- sinapic acid --- lenses --- estrogen-deficient rats --- oxidative stress --- reduced glutathione --- omega-3 --- fatty acid --- diet --- dietary assessment --- clinical survey --- eye disease --- dry eye --- age-related macular degeneration --- food frequency questionnaire --- CODS --- clinical practice guidelines --- systematic reviews --- age-related macular degeneration --- nutritional supplements --- diet --- nutrition --- AGREE II --- Cucurbita argyrosperma --- corneal chemical burn --- angiogenesis --- corneal neovascularization (CNV) --- vascular endothelial growth factor (VEGF) --- interleukin-1? (IL-1?) --- cyclooxigenase-2 (COX-2) --- nuclear factor-kappaB (NF-?B) --- dietary antioxidants --- antioxidant supplements --- lens --- cataract --- n/a

Listing 1 - 4 of 4
Sort by
Narrow your search

Publisher

MDPI - Multidisciplinary Digital Publishing Institute (3)

CABI (1)


License

CC by-nc-nd (4)


Language

english (4)


Year
From To Submit

2020 (2)

2017 (1)

106 (1)