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Plant polyamines in stress and development

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889193035 Year: Pages: 140 DOI: 10.3389/978-2-88919-303-5 Language: English
Publisher: Frontiers Media SA
Subject: Chemistry (General) --- Botany --- Science (General)
Added to DOAB on : 2016-02-05 17:24:33
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Polyamines are small aliphatic polycations which have been involved in key stress and developmental processes in plants. In the recent years, compelling genetic and molecular evidences point to polyamines as essential metabolites required for resistance to drought, freezing, salinity, oxidative stress among other type of abiotic and biotic stresses. In addition to their role as stress-protective compounds, polyamines participate in key developmental processes mediated by specific signaling pathways or in cross-regulation with other plant hormones. Our Research Topic aims to integrate the multiple stress and developmental regulatory functions of polyamines in plants under a genetic, molecular and evolutionary perspective with special focus on signaling networks, mechanisms of action and metabolism regulation.

Polyamine Metabolism in Disease and Polyamine-Targeted Therapies

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ISBN: 9783039211524 9783039211531 Year: Pages: 240 DOI: 10.3390/books978-3-03921-153-1 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2019-12-09 11:49:15
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Polyamines are ubiquitous polycations essential for all cellular life. The most common polyamines in eukaryotes, spermine, spermidine, and putrescine, exist in millimolar intracellular concentrations that are tightly regulated through biosynthesis, catabolism, and transport. Polyamines interact with, and regulate, negatively charged macromolecules, including nucleic acids, proteins, and ion channels. Accordingly, alterations in polyamine metabolism affect cellular proliferation and survival through changes in gene expression and transcription, translation, autophagy, oxidative stress, and apoptosis. Dysregulation of these multifaceted polyamine functions contribute to multiple disease processes, thus their metabolism and function have been targeted for preventive or therapeutic intervention. The correlation between elevated polyamine levels and cancer is well established, and ornithine decarboxylase, the rate-limiting biosynthetic enzyme in the production of putrescine, is a bona fide transcriptional target of the Myc oncogene. Furthermore, induced polyamine catabolism contributes to carcinogenesis that is associated with certain forms of chronic infection and/or inflammation through the production of reactive oxygen species. These and other characteristics specific to cancer cells have led to the development of polyamine-based agents and inhibitors aimed at exploiting the polyamine metabolic pathway for chemotherapeutic and chemopreventive benefit. In addition to cancer, polyamines are involved in the pathologies of neurodegenerative diseases including Alzheimer’s and Parkinson’s, parasitic and infectious diseases, wound healing, ischemia/reperfusion injuries, and certain age-related conditions, as polyamines are known to decrease with age. As in cancer, polyamine-based therapies for these conditions are an area of active investigation. With recent advances in immunotherapy, interest has increased regarding polyamine-associated modulation of immune responses, as well as potential immunoregulation of polyamine metabolism, the results of which could have relevance to multiple disease processes. The goal of this Special Issue of Medical Sciences is to present the most recent advances in polyamine research as it relates to health, disease, and/or therapy.

Keywords

polyamine transport inhibitor --- Drosophila imaginal discs --- difluoromethylorthinine --- DFMO --- polyamine --- cancer --- metabolism --- difluoromethylornithine --- polyamine transport inhibitor --- pancreatic ductal adenocarcinoma --- curcumin --- diferuloylmethane --- ornithine decarboxylase --- polyamine --- NF-?B --- chemoprevention --- carcinogenesis --- polyphenol --- ornithine decarboxylase --- polyamines --- untranslated region --- polyamines --- ?-difluoromethylornithine --- polyamine transport system --- melanoma --- mutant BRAF --- spermine --- spermidine --- putrescine --- polyamine metabolism --- mast cells --- eosinophils --- neutrophils --- M2 macrophages --- airway smooth muscle cells --- Streptococcus pneumoniae --- polyamines --- pneumococcal pneumonia --- proteomics --- capsule --- complementation --- metabolism --- cadaverine --- polyamines --- ornithine decarboxylase --- difluoromethylornithine --- eflornithine --- DFMO --- African sleeping sickness --- hirsutism --- colorectal cancer --- neuroblastoma --- aging --- atrophy --- autophagy --- oxidative stress --- polyamines --- skeletal muscle --- spermidine --- spermine oxidase --- transgenic mouse --- immunity --- T-lymphocytes --- B-lymphocytes --- tumor immunity --- metabolism --- epigenetics --- autoimmunity --- polyamines --- ornithine decarboxylase --- polyamine analogs --- spermidine/spermine N1-acetyl transferase --- spermine oxidase --- bis(ethyl)polyamine analogs --- breast cancer --- MCF-7 cells --- transgenic mice --- polyamines --- MYC --- protein synthesis in cancer --- neuroblastoma --- protein expression --- antizyme 1 --- ornithine decarboxylase --- CRISPR --- human embryonic kidney 293 (HEK293) --- cell differentiation --- DFMO --- ornithine decarboxylase --- osteosarcoma --- polyamines --- polyamines --- polyamine metabolism --- antizyme --- antizyme inhibitors --- ornithine decarboxylase --- Snyder-Robinson Syndrome --- spermine synthase --- X-linked intellectual disability --- polyamine transport --- spermidine --- spermine --- transglutaminase

Biogenic Amines on Food Safety

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ISBN: 9783039210541 9783039210558 Year: Pages: 202 DOI: 10.3390/books978-3-03921-055-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2019-08-28 11:21:27
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Biogenic amines have been known for some time. These compounds are found in varying concentrations in a wide range of foods (fish, cheese, meat, wine, beer, vegetables, etc.) and their formations are influenced by different factors associated to those foods (composition, additives, ingredients, storage, microorganism, packaging, handing, conservation, etc.). The intake of foods containing high concentrations of biogenic amines can present a health hazard. Additionally, they have been used to establish indexes in various foods in order to signal the degree of freshness and/or deterioration of food. Nowadays, there has been an increase in the number of food poisoning episodes in consumers associated with the presence of these biogenic amines, mainly associated with histamines. Food safety is one of the main concerns of the consumer and safety agencies of different countries (EFSA, FDA, FSCJ, etc.), which have, as one of their main objectives, to control these biogenic amines, principally histamine, to assure a high level of food safety.Therefore, it is necessary to deepen our understanding of the formation, monitoring and reduction of biogenic amines during the development, processing and storage of food, even the effect of biogenic amines in consumers after digestion of foods with different levels of these compounds.With this aim, we are preparing a Special Issue on the topic of ""Biogenic Amines in Food Safety"", and we invite researchers to contribute original and unpublished research articles and reviews articles that involve studies of biogenic amines in food, which can provide an update to our knowledge of these compounds and their impacts on food quality and food safety.

Technological Eco-Innovations for the Quality Control and the Decontamination of Polluted Waters and Soils

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ISBN: 9783039284641 9783039284658 Year: Pages: 226 DOI: 10.3390/books978-3-03928-465-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Environmental Sciences --- Environmental Technology
Added to DOAB on : 2020-04-07 23:07:09
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The Special Issue “Technological Eco-Innovations for the Quality Control and the Decontamination of Polluted Waters and Soils” deals with the most recent research activities carried out at lab and field scale on eco-sustainable tools for the remediation of contaminated environmental substrates. It is particularly devoted to highlight the relevance of biological organisms (plants, microbes, algae) to assess the chemical contamination in water and soil and to remediate such matrices from the pollution caused by the human activities. Therefore, bioremediation is a primary focus of most of the articles published within the present Special Issue. Bioremediation is a promising environmentally friendly technology to deal with the chemical pollution in different ecosystem compartments and its integration with the traditional approaches might represent a

Keywords

chlorophyll fluorescence --- industrial crop --- metal tolerance --- phytomanagement --- phytoremediation --- soil pollution --- coal --- soil --- water --- bioremediation --- Ralstonia sp. --- sulfur --- synthetic zeolite --- removal --- 2,4-D --- MCPA --- plant secondary metabolites --- ferulic acid --- syringic acid --- biodegradation --- ecotoxicity --- bioremediation --- biostimulation --- diesel oil --- indigenous microorganisms --- kinetics --- dielectric permittivity --- acclimation --- Brassica napus --- salt stress --- chlorophyll fluorescence --- photosynthesis --- anti-oxidant enzymes --- polyamines --- proline --- phytoremediation --- water pollution --- DDT --- TNT --- heavy metals --- cesium ions --- Tagetes patula --- Festuca arundinacea --- bottom urban sediment --- phytoremediation --- plant growth promoting bacteria --- oxidative stress --- plant stress reactions --- phytoremediation --- heavy metals --- energy crops --- pollution --- water contamination --- chlorophyll fluorescence --- mining wastes --- iron and manganese minerals --- water filtration --- arsenic adsorption --- geostatistical analysis --- geological heterogeneity --- dissolved organic carbon --- autochthonous microbial community --- urban sediments --- PCDDs/PCDFs --- rhizobacterial inoculants --- bioremediation --- phytoremediation --- natural-based remediation strategies --- Monviso clone --- plant physiology --- antioxidant defence --- soil microbial communities --- microscope --- bacterial contamination --- water contamination --- artificial intelligence

Salinity Tolerance in Plants

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ISBN: 9783039210268 9783039210275 Year: Pages: 422 DOI: 10.3390/books978-3-03921-027-5 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Biochemistry
Added to DOAB on : 2019-06-26 10:09:00
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Salt stress is one of the most damaging abiotic stresses because most crop plants are susceptible to salinity to different degrees. According to the FAO, about 800 million Has of land are affected by salinity worldwide. Unfortunately, this situation will worsen in the context of climate change, where there will be an overall increase in temperature and a decrease in average annual rainfall worldwide. This Special Issue presents different research works and reviews on the response of plants to salinity, focused from different points of view: physiological, biochemical, and molecular levels. Although an important part of the studies on the response to salinity have been carried out with Arabidopsis plants, the use of other species with agronomic interest is also notable, including woody plants. Most of the conducted studies in this Special Issue were focused on the identification and characterization of candidate genes for salt tolerance in higher plants. This identification would provide valuable information about the molecular and genetic mechanisms involved in the salt tolerance response, and it also supplies important resources to breeding programs for salt tolerance in plants.

Keywords

Arabidopsis --- Brassica napus --- ion homeostasis --- melatonin --- NaCl stress --- nitric oxide --- redox homeostasis --- Chlamydomonas reinhardtii --- bZIP transcription factors --- salt stress --- transcriptional regulation --- photosynthesis --- lipid accumulation --- Apocyni Veneti Folium --- salt stress --- multiple bioactive constituents --- physiological changes --- multivariate statistical analysis --- banana (Musa acuminata L.) --- ROP --- genome-wide identification --- abiotic stress --- salt stress --- MaROP5g --- rice --- genome-wide association study --- salt stress --- germination --- natural variation --- Chlamydomonas reinhardtii --- salt stress --- transcriptome analysis --- impairment of photosynthesis --- underpinnings of salt stress responses --- chlorophyll fluorescence --- J8-1 plum line --- mandelonitrile --- Prunus domestica --- redox signalling --- salicylic acid --- salt-stress --- soluble nutrients --- Arabidopsis thaliana --- VOZ --- transcription factor --- salt stress --- transcriptional activator --- chlorophyll fluorescence --- lipid peroxidation --- Na+ --- photosynthesis --- photosystem --- RNA binding protein --- nucleolin --- salt stress --- photosynthesis --- light saturation point --- booting stage --- transcriptome --- grapevine --- salt stress --- ROS detoxification --- phytohormone --- transcription factors --- Arabidopsis --- CDPK --- ion homeostasis --- NMT --- ROS --- salt stress --- antioxidant enzymes --- Arabidopsis thaliana --- ascorbate cycle --- hydrogen peroxide --- reactive oxygen species --- salinity --- SnRK2 --- RNA-seq --- DEUs --- flax --- NaCl stress --- EST-SSR --- Salt stress --- Oryza sativa --- proteomics --- iTRAQ quantification --- cell membrane injury --- root activity --- antioxidant systems --- ion homeostasis --- melatonin --- salt stress --- signal pathway --- SsMAX2 --- Sapium sebiferum --- drought, osmotic stress --- salt stress --- redox homeostasis --- strigolactones --- ABA --- TGase --- photosynthesis --- salt stress --- polyamines --- cucumber --- abiotic stresses --- high salinity --- HKT1 --- halophytes --- glycophytes --- poplars (Populus) --- salt tolerance --- molecular mechanisms --- SOS --- ROS --- Capsicum annuum L. --- CaDHN5 --- salt stress --- osmotic stress --- dehydrin --- Gossypium arboretum --- salt tolerance --- single nucleotide polymorphisms --- association mapping. --- n/a

Polymer Clay Nano-composites

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ISBN: 9783039216529 9783039216536 Year: Pages: 246 DOI: 10.3390/books978-3-03921-653-6 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2019-12-09 11:49:16
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This Special Issue focuses on the current state-of-the-art of “Polymer Clay Nano-Composites” for biomedical, anticorrosion, antibacterial, and other applications. Clay–polymer composite nanomaterials represent an emerging area of research. Loading polymers with clay particles essentially enhances the composite strength features. Of particular interest are different nano-assembly methods, such as silane mono and multilayers, polyelectrolyte layer-by-layer assembly, and others. An important development was reached for tubular and fibrous clay nanoparticles, such as halloysite, sepiolite, and imogolite. Polymer clay nanoparticles can be prepared as sheets with 1-nm thickness and width of a few hundred nm (e.g., kaolin and montmorillonite). Fibrous clays significantly reinforce the nano-composites in the assembly with biopolymers and other green polymers, leading to functional hybrid bio nano-composites. The scope of this Special Issue comprehensively includes the synthesis and characterization of polymer clay nano-composites used for several applications, including nano-clay polymer composites and hybrid nano-assemblies.

Keywords

polyimide --- graphene oxide --- composite --- mechanical properties --- indentation recovery --- AFM --- carbon fibers --- surface grafting --- halloysite nanotubes --- polymer composites --- interface --- fish gelatin --- halloysite nanotubes --- glycerol --- mechanical properties --- water resistance --- LAP --- hyaluronic acid --- doxorubicin --- CD44 receptor targeted --- sacrificial bond --- ionic network --- organic montmorillonite --- 1,2-polybutadiene --- in-situ intercalation --- clay–polymer nanocomposites --- atrazine --- radical polymerization --- hexadecyltrimethylammonium bromide --- phenyltrimethylammonium chloride --- FTIR --- TGA --- adsorption --- dental resins --- nanocomposite materials --- organically modified clays --- montmorillonite --- intercalation --- nanotechnology --- ammonium persulfate --- fuzzy optimization --- N,N?-methylenebisacrylamide --- Pareto set --- polyacrylic acid --- swelling capacity --- variable cost --- polyethylene oxide --- montmorillonite clays --- Pd catalysis --- catalytic composite --- positron annihilation --- doubly functionalized montmorillonite --- polystyrene --- soap-free emulsion polymerization --- thermal stability --- tribological property --- organo-clays --- polyamines --- clay-amine interaction mechanisms --- structure effects --- la uptake and release --- layered silicate --- sericite --- CTAB --- intercalation stability --- nanocomposites --- gelation kinetics --- sol–gel transition --- water shutoff --- silica sol --- cellulose nanofibrils --- halloysite nanotubes --- supercritical CO2 --- polystyrene foam --- blowing agent --- in situ polymerization --- attapulgite/polypyrrole nanocomposite --- halloysite nanotubes --- polysaccharide --- interfacial interactions --- reinforcing --- adsorption --- dispersion --- coatings --- whey protein isolate --- nanocomposites --- nanoclay, barrier --- morphology --- n/a

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