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Public policy is regularly shaken by health crises or unexpected discoveries; future directions in toxicology assessment are therefore urgently needed. Convergent evidences suggest endocrine or nervous disrupting effects of pesticides, as well as effects on wildlife and the environment. These effects are amplified by the use of surfactants and/or combinations of different active principles. The usual concepts of regulatory toxicology are challenged by endocrine, nervous or immune disruption, or epigenetic effects. Indeed, most pollutants alter cell-cell communication systems to promote chronic diseases. They may accumulate in the food chain. Mixtures effects with other pollutants may change their bioavailability and their toxicity. The lack of scientific knowledge in these matters has large costs for public health. This Research Topic focuses on the toxic effects of pesticides associated with large scale cultivation of genetically modified (GM) plants.

Pesticides --- GM crops --- Toxicity --- Multidisciplinary research --- Bt toxins --- glyphosate --- Neonicotinoids

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There has been an epochal shift: the possibility of a global climate crisis is now upon us. Pollution, the poison of pesticides, the exhaustion of natural resources, falling water tables, growing social inequalities – these are all problems that can no longer be treated separately. The effects of global warming have a cumulative impact, and it is not a matter of a crisis that will “pass” before everything goes back to “normal.” Our governments are totally incapable of dealing with the situation. Economic warfare obliges them to stick to the goal of irresponsible, even criminal, economic growth, whatever the cost. It is no surprise that people were so struck by the catastrophe in New Orleans. The response of the authorities – to abandon the poor whilst the rich were able to take shelter – is a symbol of the coming barbarism.

pesticides --- global climate crisis --- falling water tables --- pollution --- growing social inequalities --- global warming --- exhaustion of natural resources

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This book is a collection of 13 innovative papers describing the state of the art and the future perspectives in solid-phase extraction covering several analytical fields prior to the use of gas or liquid chromatographic analysis. New sorptive materials are presented including carbon nanohorn suprastructures on paper support, melamine sponge functionalized with urea–formaldehyde co-oligomers, chiral metal–organic frameworks, UiO-66-based metal–organic frameworks, and fabric phase sorptive media for various applications. Solid-phase extraction can be applied in several formats aside from the conventional cartridges or mini-column approach, e.g., online solid-phase extraction, dispersive solid-phase microextraction, and in-syringe micro-solid-phase extraction can be very helpful for analyte pre-concentration and sample clean-up. Polycyclic musks in aqueous samples, 8-Nitroguanine in DNA by chemical derivatization antibacterial diterpenes from the roots of salvia prattii, perfluoroalkyl substances (PFASs) in aater samples by bamboo charcoal-based SPE, parabens in environmental water samples, benzotriazoles as environmental pollutants, organochlorine pesticide residues in various fruit juices and water samples and synthetic peptide purification are among the applications cited in this collection. All these outstanding contributions highlight the necessity of this analytical step, present the advantages and disadvantages of each method and focus on the green analytical chemistry guidelines that have to be fulfilled in current analytical practices.

graphene --- solid-phase extraction --- polycyclic musks --- water --- GC–MS/MS --- online solid-phase extraction --- LC-MS/MS --- peroxynitrite --- nitrated DNA lesion --- derivatization --- isotope-dilution --- Salvia prattii --- antibacterial diterpenes --- hydrophilic solid-phase extraction --- preparative high-performance liquid chromatography --- bamboo charcoal --- solid-phase extraction --- perfluoroalkyl acids --- liquid chromatography–tandem mass spectrometry --- carbon nanohorns --- sorptive phase --- paper --- microextraction --- antidepressants --- in-syringe micro solid-phase extraction --- personal care products --- response surface methodology --- parabens --- wastewater --- benzotriazoles --- solid-phase extraction --- environmental samples --- solid-phase extraction --- melamine sponge --- urea-formaldehyde co-oligomers --- HPLC-DAD --- metal-organic frameworks --- enantiomeric excess --- chiral compounds --- solid-phase extraction --- metal-organic frameworks --- dispersive solid-phase extraction --- organic pollutants --- analyte partitioning --- FPSE --- in-house loaded SPE --- HPLC-PDA --- method validation --- IBD --- extraction --- fabric phase sorptive extraction --- gas chromatography-mass spectrometry --- organochlorine pesticides --- sample preparation --- peptide --- solid phase extraction (SPE) --- preparative purification --- gradient elution --- solid phase peptide synthesis

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Integrated Water Resources Management (IWRM) has become a global paradigm for the governance of surface, coastal and groundwaters. This Special Issue contains twelve articles related to the transfer of IWRM policy principles. The articles explore three dimensions of transfer—causes, processes, outcomes—and offer a theoretically inspiring, methodologically rich and geographically diverse engagement with IWRM policy transfer around the globe. As such, they can also productively inform a future research agenda on the ‘dimensional’ aspects of IWRM governance. Regarding the causes, the contributions apply, criticise, extend or revise existing approaches to policy transfer in a water governance context, asking why countries adopt IWRM principles and what mechanisms are in place to understand the adoption of these principles in regional or national contexts. When it comes to processes, articles in this Special Issue unpack the process of policy transfer and implementation and explore how IWRM principles travel across borders, levels and scales. Finally, this set of papers looks into the outcomes of IWRM policy transfer and asks what impact IWRM principles, once implemented, gave on domestic water governance, water quality and water supply, and how effective IWRM is at addressing critical water issues in specific countries.

dam --- local communities --- lived experiences --- environmental narratives --- Cambodia --- transitions --- water management regimes --- water resource management --- niches --- visions --- agency --- ocean governance --- fisheries management --- ecosystem-based management --- overfishing --- sustainable fishing --- European Union --- Turkey --- Europeanisation --- institutions --- policy transfer --- Water Framework Directive --- drinking water --- agriculture --- EU policy --- governance --- integrated scientific support --- water quality --- nitrates --- pesticides --- environmental policy --- policy coherence --- environmental governance --- integrated catchment management --- catchment --- conservation authorities --- governance --- governmentality --- integrated water resources management (IWRM) --- watershed councils --- Ontario --- Oregon --- Integrated Water Resources Management --- Integrated Urban Water Management --- urban water security --- governance --- Singapore --- Hong Kong --- process tracing --- Water Framework Directive --- policy implementation --- integrated water resources management --- river basin planning --- public participation --- water governance --- scale --- top-down and bottom-up --- estuaries --- governance --- sustainability --- governance models --- integrated water resources management --- IWRM --- Water Framework Directive --- WFD --- participation --- United Kingdom --- England --- water governance --- IWRM --- integrated water resources management --- drivers --- EU water framework directive --- implementation --- coordination --- participation --- Germany --- water governance --- polycentricity --- integrated water resources management --- IWRM --- policy transfer --- water governance --- Water Framework Directive --- learning

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Riverbank filtration (RBF) schemes for the production of drinking water are increasingly challenged by new constituents of concern, such as organic micropollutants and pathogens in the source water and hydrological flow variations due to weather extremes. RBF and new technology components are integrated and monitoring and operating regimes are adopted to further optimize water treatment in bank filtration schemes for these new requirements. This Special Issue presents results from the EU project AquaNES “Demonstrating synergies in combined natural and engineered processes for water treatment systems” (www.aquanes.eu). Additionally, papers from other research groups cover the efficiency of bank filtration and post-treatment, advantages and limitations of combining natural and engineered processes, parameter-specific assessment of removal rates during bank filtration, and the design and operation of RBF wells. The feasibility, design, and operation of RBF schemes under specific site conditions are highlighted for sites in the US, India, and South Korea

riverbank filtration --- removal efficacy --- dissolved organic carbon (DOC) --- pesticides --- pharmaceutical residues --- riverbank filtration --- organic matter degradation --- manganese --- riverbed --- climate change --- floods --- droughts --- column experiments --- PHREEQC --- decentralized capillary nanofiltration --- anoxic --- suboxic --- organic micropollutants --- bank filtrate --- groundwater --- sulphate --- dissolved organic matter --- high temperature --- sub-oxic conditions --- organic matter composition --- PARAFAC-EEM --- LC-OCD --- redox sensitivity --- micropollutants --- oxypurinol --- gabapentin --- river bank filtration --- hydrological trends --- sustainable water production --- well structure remodeling --- point-bar alluvial setting --- riverbank filtration --- site investigation --- hydrochemistry --- subsurface geology --- riverbank filtration --- organic micropollutants --- water quality --- environmental monitoring --- riverbank filtration --- collector wells --- performance --- entrance velocity --- river bank filtration --- attenuation --- organic micropollutants --- pharmaceuticals --- riverbank filtration --- small communities --- disinfection by-products --- trihalomethanes --- riverbank filtration (RBF) --- Krishna River --- southern India --- water treatment --- water quality --- salinity --- river bank filtration --- ultrafiltration --- surface water treatment --- energy efficiency --- out/in membrane comparison --- inline electrolysis --- bank filtration --- biofilm --- clogging --- filter cake --- pathogen barrier --- pressure loss --- slow sand filtration --- electro-chlorination --- smart villages --- disinfection --- river bank filtration --- rural water supply, online monitoring --- dissolved organic matter --- fluorescence excitation-emission matrix --- LC-OCD --- Nakdong River --- riverbank filtration --- bank filtration --- drinking water treatment --- inorganic chemicals --- organic micropollutants --- Ganga --- Yamuna --- Damodar --- riverbank filtration --- water quality --- organic carbon --- nitrate --- heavy metals --- microorganisms --- riverbank filtration --- riverside water source --- analytical method --- mirror-image method --- optimization --- riverbank filtration --- water quality --- bank filtrate portion --- iron --- manganese --- microorganisms --- system costs --- water supply --- storage tank --- drinking water hydropower --- turbine --- energy generation --- renewable energy