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Los rebaños de Gerión

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ISBN: 9788495555175 9788490961100 Year: Language: Spanish
Publisher: Casa de Velázquez
Added to DOAB on : 2017-07-04 10:34:03
License: OpenEdition licence for Books

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Desde el mito griego –los rebaños de Gerión– al Honrado Concejo de la Mesta, la Península Ibérica ha sido famosa tierra de pastores. Sin embargo, la importancia social y económica de esta granjería –y de su modalidad más característicamente hispana, la trashumancia–, es difícil de conceptualizar históricamente, porque todo lo pastoril no sólo elude al historiador, sino que resulta opaco a su mirada: enseres perecederos y viviendas temporales, modos de vida cuasi nómadas y, sobre todo, activid...

«Que dorénavant chacun fuie paillardise, oisiveté, gourmandise…» Réforme et contrôle des moeurs

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ISBN: 9782889300969 Year: Pages: 468 DOI: 10.26530/OAPEN_624513 Language: French
Publisher: Editions Alphil Presses universitaires suisses Grant: Swiss National Science Foundation (SNSF) - OAPEN-CH - 170310
Subject: History
Added to DOAB on : 2017-03-11 11:01:27
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Neuchâtel adopted the Reformation in 1530. What impact did this decision by the citizens of the city have on the population? This book describes the disci-pline that has since surrounded the parishioners of the canton of Neuchâtel and the lordship of Valangin and evoked three centuries of Neuchâtel consis-tories. Based on the analysis of thousands of cases, it draws back the cur-tain on daily life, love, the revolts of a small population, mostly rural, in which the sources speak only rarely.

Élites et pouvoirs locaux : La France du Sud-Est sous la Troisième République

Authors: ---
ISBN: 9782729710583 DOI: 10.4000/books.pul.17281 Language: French
Publisher: Presses universitaires de Lyon
Subject: History
Added to DOAB on : 2019-12-04 12:20:44
License: OpenEdition Licence for Books

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L'ambition de cet ouvrage est de contribuer à une histoire et à une sociologie des élites et des pouvoirs locaux sous la Troisième République, à partir de travaux portant sur leurs profils, leurs représentations, leur permanence et leur renouvellement ainsi que sur leurs attitudes dans le conflit traditionnel entre Paris et la province. Il s'agit donc de tenter de reconstituer, de manière empirique, un certain nombre de « configurations » et de réseaux de pouvoir afin de mieux saisir l'armature du contrôle politique et social, et par conséquent, les figures concrètes de la gouvernance des sociétés locales. Les champs d'investigation englobent ici la dimension communale, départementale et régionale sur l'ensemble du territoire de la France du Sud-Est.

Mitochondrial Dysfunction in Aging and Diseases of Aging

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ISBN: 9783039213276 9783039213283 Year: Pages: 270 DOI: 10.3390/books978-3-03921-328-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2019-12-09 11:49:15
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This collection of review articles authored by international experts pulls together current information about the role of mitochondria in aging and diseases of aging. Mitochondria are vitally important cellular organelles and undergo their own aging process becoming less efficient in aged animals including humans. These changes have wide-ranging significance contributing to immune dysfunction (autoimmunity and immune deficiency), inflammation, delayed healing, skin and retinal damage, cancer and most of the degenerative diseases of aging. Mitochondrial aging predisposes to drug toxicity in the geriatric population and to many of the features of normal aging. The research detailed in this book summarizes current understanding of the role of mitochondria in the complex molecular changes of aging, moving on to specific diseases of aging. Mitochondrial dysfunction is an important target for development of treatments for aging and disease. The last article details how exercise is a treatment and combats many features of the aging process.

Keywords

aging --- mitochondria --- inflammation --- innate immunity --- adaptive immunity --- immunosenescence --- cell danger response --- healing cycle --- mitochondria --- purinergic signaling --- metabokines --- sphingolipids --- integrated cell stress response --- de-emergence --- crabtree effect --- pasteur effect --- coenzyme Q10 --- aging --- age-related diseases --- mitochondrial dysfunction --- mitochondria --- skin --- ageing --- reactive oxygen species --- photoageing --- 25(OH)D --- 1,25(OH)2D --- aging --- cytokines --- inflammation --- morbidity and mortality --- prevention --- reactive oxygen species --- ultraviolet --- aging --- mitochondria --- retina --- optic nerve --- diabetic retinopathy --- age-related macular degeneration --- glaucoma --- drug-induced mitochondrial toxicity --- polypharmacy --- aging --- mitochondrial dysfunction --- insulin resistance --- type 2 diabetes --- mitochondrial transfer --- exosomes --- mitochondrial --- genetic mutations --- cardiovascular disease --- heart failure --- cardiomyopathy --- mitochondria --- cancer --- nucleotide metabolism --- DNA damage --- NAD+ --- mitochondria --- ALS --- axonal transport --- mitophagy --- SOD1 --- Miro1 --- PINK1 --- Parkin --- multiple sclerosis --- mitochondria --- neuroinflammation --- neurodegeneration --- Parkinson’s disease --- mitochondria --- ageing --- neurodegenerative disease --- Alzheimer’s disease --- eIF2? --- metabolism --- mitochondria --- proteostasis --- stress response --- aging --- exercise --- mitochondria --- aerobic --- ROS --- inflammation --- senescence --- lysosome --- autophagy --- mitophagy --- n/a

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