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Nanofibers, particularly those of a carbonaceous content, have received increased interest in the past two decades due to their outstanding physico-chemical characteristics and their possibility to form and contribute towards a plethora of potentially advantageous materials for consumer, industrial and medical applications. Despite this, and together with the numerous research studies and published articles that have sought to investigate these aspects, the potential impact of CNTs is still not understood. Whether or not nanofibers may be able to provide a sophisticated alternative to conventional materials is still debatable, whilst their effects upon both environmental and human health are highly equivocal. How nanofibers are conceived can determine how they may interact with different environments, such as the human body. Understanding each key step of the synthesis and production of nanofibers to their use within potential applications is therefore essential in gaining an insight into how they may be perceived by any biological system and environment. Thus, obtaining such information will enable all scientific communities to begin to realize the potential advantages posed by nanofibers. The aim of this Special Issue therefore, was to provide a collective overview of nanofibers; ‘from synthesis to application’. The Issue particularly focuses upon carbon-based nanofibers, but also highlights alternative nanofiber types. Emphasis is given holistically, with articles discussing the production routes of nanofibers, their plight during their life-cycle (origin to applied form and effects over time), as well as how nanofibers could either incite conflict, or provide aid to human and environmental health.
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Electrospinning is a versatile and effective technique widely used to manufacture nanofibrous structures from a diversity of materials (synthetic, natural or inorganic). The electrospun nanofibrous meshes’ composition, morphology, porosity, and surface functionality support the development of advanced solutions for many biomedical applications. The Special Issue on “Electrospun Nanofibers for Biomedical Applications” assembles a set of original and highly-innovative contributions showcasing advanced devices and therapies based on or involving electrospun meshes. It comprises 13 original research papers covering topics that span from biomaterial scaffolds’ structure and functionalization, nanocomposites, antibacterial nanofibrous systems, wound dressings, monitoring devices, electrical stimulation, bone tissue engineering to first-in-human clinical trials. This publication also includes four review papers focused on drug delivery and tissue engineering applications.
sol-gel --- electrospinning --- hydroxyapatite --- nanofiber --- antibacterial --- titanium --- antibacterial coatings --- electrospinning --- nanocomposite coatings --- TiO2 photocatalytic --- orthopedic infections --- electrospinning --- 3D printing --- nanofibers --- encapsulation --- protein diffusion --- in vivo tissue engineering --- immuno-isolation --- transplantation --- electrospinning --- sputtering --- drug delivery --- wound dressing --- biocompatibility --- tissue engineering --- biomimetic scaffolds --- gelatin --- electrospinning --- micromolding --- biomaterials --- poly(lactic acid) (PLLA) --- bioactive glass --- scaffolds --- electrospinning --- composite fibres --- bone regeneration --- poly(vinylidene fluoride) --- composite nanofiber --- piezoelectricity --- antioxidant activity --- well-aligned nanofibers --- P(VDF-TrFE) --- piezoelectric nanogenerator --- preosteoblasts electrospinning --- silicone modified polyurethane nanofibers --- physical properties --- cell attachment --- cell proliferation --- cytotoxicity --- biopolymers --- packaging --- pharmaceutical --- biomedical --- electrospinning --- alginate --- gelatin fibers --- ZnO particles --- antibacterial activity --- electrospinning --- nanofibers --- fabrication --- therapeutics --- biomedical applications --- antibody immobilization --- electrospun nanofibers --- TNF-? capture --- human articular chondrocytes --- rheumatoid arthritis --- nanofibers --- microfluidic chip --- electrospinning --- live assay --- hepatocellular carcinoma cells --- PLA95 --- biocompatibility --- guided tissue regeneration (GTR) --- electrospinning --- electrospun fiber mats --- mechanobiology --- glioblastoma --- biomaterials --- finite element modeling --- electrospun nanofibers --- cancer treatment --- drug release --- nanomedicine --- biocompatible polymers --- hyperthermia
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Several promising techniques have been developed to overcome the poor solubility and/or membrane permeability properties of new drug candidates, including different fiber formation methods. Electrospinning is one of the most commonly used spinning techniques for fiber formation, induced by the high voltage applied to the drug-loaded solution. With modifying the characteristics of the solution and the spinning parameters, the functionality-related properties of the formulated fibers can be finely tuned. The fiber properties (i.e., high specific surface area, porosity, and the possibility of controlling the crystalline–amorphous phase transitions of the loaded drugs) enable the improved rate and extent of solubility, causing a rapid onset of absorption. However, the enhanced molecular mobility of the amorphous drugs embedded into the fibers is also responsible for their physical–chemical instability. This Special Issue will address new developments in the area of electrospun nanofibers for drug delivery and wound healing applications, covering recent advantages and future directions in electrospun fiber formulations and scalability. Moreover, it serves to highlight and capture the contemporary progress in electrospinning techniques, with particular attention to the industrial feasibility of developing pharmaceutical dosage forms. All aspects of small molecule or biologics-loaded fibrous dosage forms, focusing on the processability, structures and functions, and stability issues, are included.
electrospinning --- gentamicin sulfate --- polylactide-co-polycaprolactone --- drug release kinetics --- tissue engineering --- growth factor --- diabetic --- wound healing --- nanocomposite --- electrospinning --- coaxial spinning --- core-sheath nanofibers --- biomedical --- drug delivery --- electrospinning --- scale-up --- processability --- biopharmaceuticals --- oral dosage form --- grinding --- aceclofenac --- nanofiber --- electrospinning --- scanning electron microscopy --- fourier transform infrared spectroscopy --- differential scanning calorimetry --- nanotechnology --- biotechnology --- probiotics --- Lactobacillus --- Lactococcus --- electrospinning --- nanofibers --- drying --- local delivery --- viability --- antibacterial activity --- bacterial bioreporters --- drug release --- electrospinning --- microfibers --- nanofibers --- UV imaging --- wetting --- in situ drug release --- nanofibers --- electrospinning --- poorly water-soluble drug --- piroxicam --- hydroxypropyl methyl cellulose --- polydextrose --- scanning white light interferometry --- nanotechnology --- nanofibers --- traditional electrospinning --- ultrasound-enhanced electrospinning --- drug delivery system --- haemanthamine --- plant-origin alkaloid --- electrospinning --- amphiphilic nanofibers --- self-assembled liposomes --- physical solid-state properties --- drug release --- electrospinning --- PCL --- gelatin --- clove essential oil --- antibacterial --- biocompatibility --- artificial red blood cells --- electrospinning and electrospray --- pectin --- oligochitosan --- hydrogel --- microcapsules --- electrospinning --- wound dressings --- solvent casting --- 3D printing --- polymeric carrier --- n/a
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This book is comprised of important reviews and cutting-edge original research papers concerning electrospun and electrosprayed formulations in drug delivery. Electrospinning and electrospraying have, in recent years, attracted increasing attention in the pharmaceutical sector, with research in the area advancing rapidly. It is now possible to prepare extremely complex systems using multi-fluid processes, and to increase production rates to an industrial scale. Electrospun formulations can be produced under GMP conditions and are in clinical trials. In this volume, we explore a range of topics around electrospinning and electrospraying in controlled drug delivery. Four reviews cover the exciting potential of cyclodextrin-containing fibers and the many potential biomedical applications of electrospun fibers. The use of electrospinning to prepare amorphous systems and improve the dissolution rate and solubility of poorly soluble active ingredients is addressed, and the possibilities of such materials in tissue engineering are comprehensively covered. The six original research papers cover the effect of molecular properties on API release from Eudragit-based electrospun fibers; ferulic acid solid dispersions; electrospun medicines to treat psoriasis; scale up of electrospinning and its use to produce low-dose tablets; transepithelial permeation of drugs released from electrospun fibers, and the possibilities for the synergistic chemophotothermal treatment of cancer.
electrospinning --- Eudragit --- nanofibers --- drug release --- carvedilol --- poly (vinylpyrrolidone-co-vinyl acetate) --- high-speed electrospinning --- high-shear mixing --- homogenization --- Raman mapping --- sieve analysis --- amorphous composite --- coaxial electrospinning --- fast dissolution --- insoluble drug --- solid dispersion --- electrospinning --- parameters --- drug delivery --- applications --- solid dispersion --- aqueous solubility enhancement --- amorphous --- crystalline --- oral drug delivery --- electrospinning --- cyclodextrin --- electrospinning --- drug delivery --- nanofibers --- cyclodextrin-inclusion complexes --- essential oils --- electrospun nanofibers --- poly-cyclodextrin --- antibacterial --- antibiotics --- PMVE/MA --- electrospinning --- nanofibers --- capsaicin --- psoriasis --- TRPV1 --- PCL --- electrospinning --- combination therapy --- photothermal therapy --- NIR-triggered drug release --- xanthan gum --- electrospinning --- gallic acid --- permeability --- electrospinning --- tissue engineering --- drug delivery
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[This book focus on the most recent advances related to the design and processing methods of different nanobiomaterials, films, and fibers; surface functionalization strategies, including biological performance assessment and cytocompatibility; and their applications in tissue engineering strategies.]
titania nanotubes --- anodic oxidation --- biointegration --- antibacterial properties --- photocatalytic activity --- magnetic nanoparticles --- nanotechnology --- cell sheet --- odontogenic cells --- epithelial-mesenchymal interactions --- dental enamel regeneration --- cornea endothelial cells --- tissue engineering --- regeneration --- silk fibroin --- lysophosphatidic acid --- graphene --- nanomaterials --- dental stem cells --- antibacterial activity --- dental implant --- bone regeneration --- osteoclastogenesis --- RANK-RANKL-OPG --- mimetic peptide --- Gadolinium chelate --- MRI --- protein --- nanofibers --- biomaterials fabrication --- medicine --- tissue engineering --- wound healing --- drug delivery
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The electrospinning method has the unique ability to produce structured polymeric fibers on the micro or nano scale and to generate novel materials for food and healthcare purposes. The potential of electrospun nanofibers for human healthcare applications is promising, for example, in tissue/organ repair and regeneration, in medical diagnostics and instrumentation, and as vectors to deliver drugs and therapeutics, as biocompatible and biodegradable medical implant devices, as protective fabrics against environmental and infectious agents in hospitals and general surroundings. Furthermore, considerable effort has been directed toward developing scaffolds using biodegradable and biocompatible synthetic, natural polymers or renewable materials that enhance in vitro cell growth, while killing pathogenic bacteria cells. This Special Issue ""Electrospun Polymer Nanofibers for Food and Health Applications” will cover the latest research of electrospun nanofibres in this field including shape-memory electrospun fibre meshes with programmable cell orientation, water-absorbing nano?ber meshes for e?cient removal of excess water from kidney failure patients, and hydrogel nano?bers which can be used as a drug carrier for methylene blue.
shape memory nanofiber --- shape memory polymer --- poly(?-caprolactone) --- melting temperature --- cell orientation --- polyurethane --- water absorbing materials --- nanofibers --- electrospinning --- poly(sodium acrylate) --- hemodialysis --- carboxymethyl sago pulp --- controlled release --- electrospinning --- hydrogel --- nanofiber --- Curcuma comosa --- electrospinning --- gelatin --- S. epidermidis --- S. aureus --- electrospinning --- nanofiber mat --- ZnO --- polyacrylonitrile (PAN) --- brittleness
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Increasing attention is being paid to the development of effective technologies for the sequestration of CO2 and its storage. Hopefully, this will result in processes that can lead to its valorisation as a chemical, e.g., for the regeneration of fuels, but also for the production of intermediates. These are usually energy demands and rather slow processes, requiring energy input and catalysts. Some examples are the innovative strategies for the hydrogenation, photoconversion, or electroreduction of carbon dioxide. This book collects original research papers, reviews, and commentaries focused on the challenges related to the valorisation and conversion of CO2.
CO2 methanation --- dynamic reaction conditions --- operando XAS --- quick-EXAFS --- surface oxidation-reduction --- H2 dropout --- carbon dioxide --- CO2 electro-reduction --- metal-carbon-CNF composites --- plastic waste --- carbon-based electrodes --- carbon nanofibers --- CO2 hydrogenation --- microwaves --- ultrasound --- mechanochemistry --- catalyst preparation --- diatomite --- alkali oxide --- dimethyl carbonate --- catalysis --- carbon dioxide --- CO2 methanation --- catalysis --- water sorption --- water diffusion --- alkali promoter --- dimethyl carbonate --- catalysis --- carbon dioxide --- dehydration --- CO2 reduction --- photoreduction --- Titania --- photocatalysis --- high pressure photocatalysis --- n/a
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The Tsinghua University–University of Waterloo Joint Research Center for Micro/Nano Energy & Environment Technology (JCMEET) is a platform. It was established on Nov.11, 2017. The Chairperson of University Council of Tsinghua University, Dr. Xu Chen, and the President of the University of Waterloo, Dr. Feridun Hamdullahpur, attended the opening ceremony and unveiled the nameplate for the joint research center on 29th of March, 2018. The research center serves as a platform for researchers at both universities to conduct joint research in the targeted areas, and to meet regularly for information exchange, talent exchange, and knowledge mobilization, especially in the fields of micro/nano, energy, and environmental technologies. The center focuses on three main interests: micro/nano energy technology, micro/nano pollution control technology, and relevant fundamental research. In order to celebrate the first anniversary of the Joint Research Center, we were invited to serve as the Guest Editors of this Special Issue of Materials focusing on the topic of micro/nano-materials for clean energy and environment. It collects research papers from a broad range of topics related to micro/nanostructured materials aimed at future energy resources, low emission energy conversion, energy storage, energy efficiency improvement, air emission control, air monitoring, air cleaning, and many other related applications. This Special Issue provides an opportunity and example for the international community to discuss how to actively address the energy and environment issues that we are facing.
air filtration --- airborne nanoparticle --- particle concentration --- nanofibers --- cellulose nanofiber --- Lyocell fiber --- PM2.5 --- filter paper --- submicro-fiber --- airborne dust --- engine filtration --- loading performance --- potassium-based adsorbent --- load modification --- CO2 adsorption --- failure --- kinetics --- microscopic characteristics --- CaO --- As2O3 --- DFT --- adsorption --- oxygen carrier --- multiscale model --- product island --- oxidation kinetics --- thermal energy storage (TES) --- phase change material (PCM) --- building materials --- passive building systems --- mortar --- concrete --- flame synthesis --- flame stabilizing on a rotating surface (FSRS) --- rotational speed --- particle deposition --- Karlovitz number --- Limestone --- particle size --- sulfation --- TGA --- model --- nanoparticles --- nanoplates --- spectral blue shift --- amalgam --- water quality --- shale --- permeability measurement --- pressure decay method
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This Special Issue focuses on the synthesis and characterization of hydrogels specifically used as carriers of biological molecules for pharmaceutical and biomedical employments. Pharmaceutical applications of hydrophilic materials has emerged as one of the most significant trends in the area of nanotechnology. To propose some of the latest findings in this field, each contribution involves an in-depth analysis including different starting materials and their physico-chemical and biological properties with the aim of synthetizing high-performing devices for specific use. In this context, intelligent polymeric devices able to be morphologically modified in response to an internal or external stimulus, such as pH or temperature, have been actively pursued. In general, hydrophilic polymeric materials lead to high in vitro and/or in vivo therapeutic efficacy, with programmed site-specific feature showing remarkable potential for targeted therapy. This Special Issue serves to highlight and capture the contemporary progress in this field. Relevant resources and people to approach - American Association Pharmaceutical Scientists (AAPS): web: www.aaps.org; email: (marketing division): Marketing@aaps.org; (mmeting division): Meetings@aaps.org - International Association for Pharmaceutical Technology (APV): web: apv-mainz.de; email (managing director):
pellets 1 --- pellet diameter 2 --- crystallinity 3 --- sphericity 4 --- fast release 5 --- extended release 6 --- elastin-like polypeptide (ELPs) --- contact lens --- lacritin --- protein therapeutics --- drug delivery --- controlled release --- nanoporous silicon --- ?CD polymer --- caffeic acid --- pinocembrin --- polyphenols --- HUVECs --- polymer carriers --- drug delivery --- conjugates --- self-assemblies --- star polymers --- graft polymers --- poly(ionic liquid)s --- retinol --- “click” chemistry --- alkyne–azide reaction --- ATRP --- graft copolymers --- amphiphilic copolymers --- micellar carriers --- sustained release --- wound healing --- crosslinking --- allantoin --- equilibrium swelling ratio --- accumulative release --- thermogravimetric analysis --- lutein --- nanofibers --- polyvinyl alcohol --- sodium alginate --- injectable hydrogels --- drug delivery --- anticancer activity --- natural polymers --- synthetic polymers --- stimuli-responsive materials --- silk fibroin --- drug delivery --- gene delivery --- controlled release --- bioconjugation --- n/a
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Smart textiles are the textiles that are sensitive to any environmental conditions and can respond accordingly. Using passive and active coatings to generate high sensitivity to textiles is among the most recent research trends by engineers around the World. This has resulted in expansion in the application of smart textiles in various industrial fields including medicals, electronics and protective clothing. The aim of this special issue is to introduce the most state-of-the-art research and review articles by distinguished researchers in the field of smart coatings on textiles. The guest editor hopes that content will be useful for researchers, students and companies for continuation of research and development with the concept of smart textiles.
textile electronics --- plain weave --- touch sensor --- triboelectricity --- structural color --- electrospun nanofibers --- nanoparticle assemblies --- polymer --- photonic crystal --- optical fiber sensors --- lab-on-fiber technology --- microgel --- dip coating technique --- textile --- pilling --- image processing --- machine learning --- PLA fiber --- chitosan --- sodium alginate --- layer-by-layer method --- plasma treatment --- reactive vapor deposition --- hydrophobic --- Janus material --- absorbant --- separation --- polypropylene --- hernia meshes --- surface functionalization --- polydopamine --- smart textiles --- actuator --- wearable technology --- carbon nanotubes --- conducting polymers --- polymer actuators --- coating --- UHMWPE --- nanoparticle-laden elastomer --- oxygen-plasma treatment --- penetration resistance --- cyclodextrin --- chitosan --- electrospinning --- fiber --- assembly --- flexible electronics --- smart textiles --- conductive coatings --- e-textiles
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