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Applied Analysis of Ordinary Differential Equations

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ISBN: 9783039217267 / 9783039217274 Year: Pages: 62 DOI: 10.3390/books978-3-03921-727-4 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Mathematics
Added to DOAB on : 2019-12-09 11:49:16
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One might say that ordinary differential equations (notably, in Isaac Newton’s analysis of the motion of celestial bodies) had a central role in the development of modern applied mathematics. This book is devoted to research articles which build upon this spirit: combining analysis with the applications of ordinary differential equations (ODEs). ODEs arise across a spectrum of applications in physics, engineering, geophysics, biology, chemistry, economics, etc., because the rules governing the time-variation of relevant fields is often naturally expressed in terms of relationships between rates of change. ODEs also emerge in stochastic models—for example, when considering the evolution of a probability density function—and in large networks of interconnected agents. The increasing ease of numerically simulating large systems of ODEs has resulted in a plethora of publications in this area; nevertheless, the difficulty of parametrizing models means that the computational results by themselves are sometimes questionable. Therefore, analysis cannot be ignored. This book comprises articles that possess both interesting applications and the mathematical analysis driven by such applications.

Mercury and Methylmercury Toxicology and Risk Assessment

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ISBN: 9783038979708 / 9783038979715 Year: Pages: 142 DOI: 10.3390/books978-3-03897-971-5 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- Chemical Engineering
Added to DOAB on : 2019-06-26 08:44:06
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Mercury is a global pollutant that affects the health of both humans and ecosystems. This Special Issue collects three review papers and six research articles that report on the latest findings on the mechanisms of mercury toxicology and its impacts on environmental health. This collection of papers provides useful, new information on the mechanisms of mercury toxicity and methods of improving the risk assessment of mercury exposure.

Neonatal Screening for Critical Congenital Heart Defects

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ISBN: 9783039210480 / 9783039210497 Year: Pages: 98 DOI: 10.3390/books978-3-03921-049-7 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Social Sciences --- Sociology
Added to DOAB on : 2019-06-26 08:44:06
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Critical congenital heart defects (CCHDs) are potentially life-threatening malformations that remain a significant cause of neonatal mortality and morbidity. Failure to diagnose these conditions shortly after birth may result in acute cardiovascular collapse and death. The identification of CCHDs by routine newborn clinical examination is routine in many countries, but consistently misses over a third of cases, and, although antenatal ultrasound screening can be very effective in early diagnosis, the provision and accuracy of ultrasound screening is highly variable. As most CCHDs present with mild cyanosis (hypoxaemia), which is frequently clinically undetectable, pulse oximetry is a rapid, simple, painless method of accurately identifying hypoxaemia, which has gained popularity as a screen for CCHD. This Special Issue of the International Journal of Neonatal Screening, devoted to ""Neonatal Screening for Critical Congenital Heart Defects (CCHDs)"", will consider the evidence for CCHD screening with pulse oximetry, the acceptability and cost-effectiveness of this intervention, the additional non-cardiac conditions which it may also identify, and international experiences of introducing CCHD screening across the globe.

Compounds with Polar Metallic Bonding

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ISBN: 9783039210701 / 9783039210718 Year: Pages: 154 DOI: 10.3390/books978-3-03921-071-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Chemistry (General) --- Inorganic Chemistry
Added to DOAB on : 2019-08-28 11:21:27
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The Special Edition 'Compounds with Polar Metallic Bonding' is a collection of eight original research reports presenting a broad variety of chemical systems, analytical methods, preparative pathways and theoretical descriptions of bonding situations, with the common aim of understanding the complex interplay of conduction electrons in intermetallic compounds that possess different types of dipoles. Coulombic dipoles introduced by electronegativity differences, electric or magnetic dipoles, polarity induced by symmetry reduction—all the possible facets of the term 'polarity'—can be observed in polar intermetallic phases and have their own and, in most cases, unique consequences on the physical and chemical behaviour. Elucidation of the structure–property relationships in compounds with polar metallic bonding is a modern and growing scientific field which combines solid state physics, preparative chemistry, metallurgy, modern analytic methods, crystallography, theoretical calculations of the electronic state and many more disciplines.

Arts and Refugees: Multidisciplinary Perspectives

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ISBN: 9783039214051 / 9783039214068 Year: Pages: 100 DOI: 10.3390/books978-3-03921-406-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Social Sciences --- Sociology --- Ethnology
Added to DOAB on : 2019-12-09 11:49:15
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This book examines the relevance of artistic practices in the current debate about the integration of de facto refugees in Europe, and also in the actual integration of refugee artists into the social fabric and the artistic scene. It looks at the role of arts (music, theatre, literature, etc.) in the solidarity movements in favor of refugees occurring in a number of European cities. It also examines the trajectory of refugee artists and their strategies to claim a position in their new society and artistic scene. The included chapters represent different disciplines and different theoretical perspectives (social movement theories, social mobilization theories, and cultural participation theories

Diagnosis of Neurogenetic Disorders: Contribution of Next Generation Sequencing and Deep Phenotyping

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ISBN: 9783039216109 / 9783039216116 Year: Pages: 94 DOI: 10.3390/books978-3-03921-611-6 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Neurology
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The contribution of genomic variants to the aetiopathogenesis of both paediatric and adult neurological disease is being increasingly recognized. The use of next-generation sequencing has led to the discovery of novel neurodevelopmental disorders, as exemplified by the deciphering developmental disorders (DDD) study, and provided insight into the aetiopathogenesis of common adult neurological diseases. Despite these advances, many challenges remain. Correctly classifying the pathogenicity of genomic variants from amongst the large number of variants identified by next-generation sequencing is recognized as perhaps the major challenge facing the field. Deep phenotyping (e.g., imaging, movement analysis) techniques can aid variant interpretation by correctly classifying individuals as affected or unaffected for segregation studies. The lack of information on the clinical phenotype of novel genetic subtypes of neurological disease creates limitations for genetic counselling. Both deep phenotyping and qualitative studies can capture the clinical and patient’s perspective on a disease and provide valuable information. This Special Issue aims to highlight how next-generation sequencing techniques have revolutionised our understanding of the aetiology of brain disease and describe the contribution of deep phenotyping studies to a variant interpretation and understanding of natural history.

Bioengineering Liver Transplantation

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ISBN: 9783039217441 / 9783039217458 Year: Pages: 132 DOI: 10.3390/books978-3-03921-745-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2019-12-09 11:49:16
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The aim of this Special Issue is to review, understand, and evaluate new and exciting opportunities from the field on regenerative medicine, biomaterials, and stem cell research for the bioengineering of human liver grafts that can be applied for transplantation and personalized treatment of end-stage liver disease.The development of culture conditions for long-term expansion of LGR5+ intestinal stem cells as crypt-villus structures demonstrated the feasibility of deriving complex, organ-like structures in vitro from primary adult tissues, including the liver. Moreover, human pluripotent stem cells (hPSCs) can be applied to generate functionally maturated liver and bile duct epithelial cells.In this Special Issue, we welcome reviews and original papers focussing on hepatic cell sources, including adult hepatic stem cells, organoids, fetal and induced pluripotent stem cells, and primary cells (i.e., hepatocytes, cholangiocytes, and endothelial cells) and how these cells can be applied in tissue engineering strategies to generate implantable and personalized liver grafts. Potential topics include, but are not limited to, the following: liver tissue engineering, liver regeneration, graft repair, liver stem cells and organoids, bio-scaffolds, and 3D printing.We invite you to contribute original research papers, as well as comprehensive reviews, aligned with these themes, to advance and improve the actual state-of-the-art in liver bioengineering and providing new opportunities for the imminent medical problem of organ and tissue shortage for transplantation.

Nanogrids, Microgrids, and the Internet of Things (IoT): Towards the Digital Energy Network

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ISBN: 9783039217946 / 9783039217953 Year: Pages: 128 DOI: 10.3390/books978-3-03921-795-3 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
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Driven by new regulations, new market structures, and new energy resources, the smart grid has been the trigger for profound changes in the way that electricity is generated, distributed, managed, and consumed. The smart grid has raised the traditional power grid by using a two-way electricity and information flow to create an advanced, automated power supply network. However, these pioneering smart grid technologies must grow to adapt to the demands of the current digital society. In today’s digital landscape, we can access feasible data and knowledge that were merely inconceivable. This Special Issue aims to address the landscape in which smart grids are progressing, due to the advent of pervasive technologies like the Internet of Things (IoT). It will be the advanced exploitation of the massive amounts of data generated from (low-cost) IoT sensors that will become the main driver to evolve the concept of the smart grid, currently focused on infrastructure, towards the digital energy network paradigm, focused on service. Furthermore, collective intelligence will improve the processes of decision making and empower citizens. Original manuscripts focusing on state-of-the-art IoT networking and communications, M2M communications, cyberphysical system architectures, big data analytics or cloud computing applied to digital energy platforms, including design methodologies and practical implementation aspects, are welcome.

Brain-Computer Interfaces for Human Augmentation

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ISBN: 9783039219063 / 9783039219070 Year: Pages: 128 DOI: 10.3390/books978-3-03921-907-0 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Psychology
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The field of Brain–Computer Interfaces (BCIs) has grown rapidly in the last few decades, allowing the development of faster and more reliable assistive technologies based on direct links between the brain and an external device. Novel applications of BCIs have also been proposed, especially in the area of human augmentation, i.e., enabling people to go beyond human limitations in sensory, cognitive and motor tasks. Brain-imaging techniques, such as electroencephalography, have been used to extract neural correlates of various brain processes and transform them, via machine learning, into commands for external devices. Brain stimulation technology has allowed to trigger the activation of specific brain areas to enhance the cognitive processes associated to the task at hand, hence improving performance. BCIs have therefore extended their scope from assistive technologies for people with disabilities to neuro-tools for human enhancement. This Special Issue aims at showing the recent advances in BCIs for human augmentation, highlighting new results on both traditional and novel applications. These include, but are not limited to, control of external devices, communication, cognitive enhancement, decision making and entertainment.

Diet in Brain Health and Neurological Disorders: Risk Factors and Treatments

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ISBN: 9783039216505 / 9783039216512 Year: Pages: 68 DOI: 10.3390/books978-3-03921-651-2 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Neurology
Added to DOAB on : 2019-12-09 16:39:37
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The role of nutrition in health and disease has been appreciated from time immemorial. Around 400 B.C., Hippocrates wrote “Let food by thy medicine and medicine be thy food.” In the 12th century, the great philosopher and physician Moses Maimonides wrote “any disease that can be treated by diet should be treated by no other means.” Now, in the 21st century, we are bombarded by claims in the media of “superfoods,” wondrous nutritional supplements, and special diets that promise to cure or prevent disease, improve health and restore functioning. Much of the focus has been on neurological disease, brain health and psychological functioning (behavior, cognition, and emotion). The hyperbole aside, there has been considerable progress in the past decade in our understanding of the contribution of specific nutrients and dietary patterns to brain development, physiology, and functioning. This Special Issue of Brain Sciences is devoted to the latest research on the role of nutritional deficiencies and excesses in the genesis of brain dysfunction, and use of diet for the prevention and treatment of brain and mental disorders. Basic laboratory and clinical research studies of the immature, adult, and aged nervous system are all welcome.

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