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Cyanobacteria and Cyanotoxins: New Advances and Future Challenges

Authors: ---
ISBN: 9783039218387 / 9783039218394 Year: Pages: 246 DOI: 10.3390/books978-3-03921-839-4 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Public Health
Added to DOAB on : 2020-06-09 16:38:57
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Abstract

Cyanobacteria are a group of ubiquitous photosynthetic prokaryotes. Their occurrence has been increasing worldwide, due to anthropogenic activities and climate change. Several cyanobacterial species are able to synthesize a high number of bioactive molecules, among them, cyanotoxins (microcystins, cylindrospermopsin, nodularin, etc.), which are considered a health concern. For risk assessment of cyanotoxins, more scientific knowledge is required to perform adequate hazard characterization, exposure evaluation and, finally, risk characterization of these toxins. This Special Issue “Cyanobacteria and Cyanotoxins: New Advances and Future Challenges” presents new research or review articles related to different aspects of cyanobacteria and cyanotoxins, and contributes to providing new toxicological data and methods for a more realistic risk assessment.

Keywords

cylindrospermopsin --- in vitro --- cytotoxicity --- oxidative stress --- genotoxicity --- microcystins --- taste-and-odor compounds --- water source --- drinking water treatment plant --- cyanobacterial thresholds --- arctic --- benthic mats --- cyanotoxins --- ELISA --- 16S rRNA gene --- apoptosis --- microcystin-LR (MC-LR) --- reproductive toxicity --- resveratrol --- sirtuin 1 (SIRT1) --- Aphanizomenon flos-aquae --- blue-green algae supplements --- cyanotoxins --- microcystin --- cylindrospermopsin --- saxitoxin --- cylindrospermopsin --- monoclonal antibody --- time-resolved fluoroimmunoassay --- method validation --- detection --- cyanobacteria --- cyanotoxins --- nutrient enrichment --- akinetes --- harmful algal blooms --- PCR --- phylogenetic analyses --- microcystin-LR --- Procambarus clarkii --- energy budget --- astaxanthin --- cylindrospermopsin --- anatoxin-a --- PSP toxins --- microcystins --- cyanobacteria --- Nostocales --- drinking water --- marine cyanobacteria --- cyanotoxins --- marine sponges --- secondary metabolites --- marine natural compounds --- bioassays --- Artemia salina --- Paracentrotus lividus --- hemolytic essay --- reservoir --- Yangtze estuary --- 16S rRNA gene sequencing --- shotgun metagenomic sequencing --- bacterial community --- microbial metabolisms --- [d-Leu1]Microcystin-LR --- Lithobates catesbeianus --- tadpoles --- exposure --- Histopathological evaluation --- microcystins --- cylindrospermopsin --- method validation --- UPLC-MS/MS --- lettuce --- genotoxicity --- mutagenicity --- Cylindrospermopsin --- Microcystin-LR --- mixture

Mycotoxin Exposure and Related Diseases

Authors: ---
ISBN: 9783039287048 / 9783039287055 Year: Pages: 222 DOI: 10.3390/books978-3-03928-705-5 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Social Sciences --- Sociology
Added to DOAB on : 2020-06-09 16:38:57
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Abstract

Mycotoxins are considered the most frequently occurring natural contaminants in human and animal diets. Considering their potential toxic and carcinogenic effects, mycotoxin exposure assessment has particular importance in the context of health risk assessment. The magnitude of a given exposure allows the derivation of the associated risk and the potential for the establishment of a disease. Although food ingestion is considered a major route of human exposure to mycotoxins, other contexts may also result in exposure, such as specific occupational environments where exposure to organic dust also occurs due to the handling of organic materials. Animals could be exposed to mycotoxins through consumption of contaminated feed, subsequently entering in the food chain and thus constituting a source of exposure to humans. Human biomonitoring is considered a new frontier for the establishment of the human internal exposure to mycotoxins. Although several studies have summarized the potential outcomes associated with mycotoxin exposure, major gaps in data remain in recognizing the mycotoxins that are the cause of diseases. This book contributes provides research that supports the anticipation of potential consequences of the exposure of humans and animals to mycotoxins, future risk assessments, and the establishment of preventive measures.

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2020 (2)