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New Genetics, New Social Formations

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Book Series: Genetics and Society ISBN: 9780203962893 9780415393232 9780415759434 9781134162581 9781134162574 9781134162536 Year: DOI: 10.4324/9780203962893 Language: English
Publisher: Taylor & Francis
Subject: Medicine (General) --- Anthropology --- Sociology
Added to DOAB on : 2019-11-08 11:21:16
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New genetic technologies cut across a range of public regulatory domains and private lifeworlds, often appearing to generate an institutional void in response to the complex challenges they pose. As a result, a number of new social formations are being developed to legitimate public engagement and avoid the perceived democratic deficit that may result. Papers in this volume discuss a variety of these manifestations in a global context, including: genetic data banks committees of inquiry non-governmental organisations (NGOs) national research laboratories. These institutions, across both health and agriculture, are explored in such diverse locations as Amazonia, China, Finland, Israel, the UK and the USA. This volume exhibits a clear thematic coherence around the impact of the new genetics and their associated technologies on new social formations, and the case studies included have a significant international focus, showing a balance between theoretical and empirical approaches in this rapidly changing field. This innovative new volume will be of interest to postgraduates and professionals in the fields of sociology, social anthropology, science and technology studies, and environmental studies.

Keywords

stem --- cell --- research --- crops --- lines --- embryonic --- food --- bioethics --- discourse --- talk

Islamic Area Studies with Geographical Information Systems

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Book Series: New Horizons in Islamic Studies ISBN: 9780203401422 9780415332507 9780415665872 9781138010246 9781134320431 9781134320424 9781134320387 Year: DOI: 10.4324/9780203401422 Language: English
Publisher: Taylor & Francis
Subject: Political Science --- Science (General)
Added to DOAB on : 2019-11-08 11:21:20
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In this volume the contributors use Geographical Information Systems (GIS) to reassess both historic and contemporary Asian countries and traditionally Islamic areas. This highly illustrated and comprehensive work highlights how GIS can be applied to the social sciences. With its description of how to process, construct and manage geographical data the book is ideal for the non-specialist looking for a new and refreshing way to approach Islamic area studies.

Keywords

space --- syntax --- spatial --- data --- objects --- axial --- lines --- map --- ferghana --- valley

Product lines for digital information products

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ISBN: 9783866441330 Year: Pages: XIV, 220 p. DOI: 10.5445/KSP/1000006402 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Computer Science
Added to DOAB on : 2019-07-30 20:02:02
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Digital information products are an important class of widely used digital products, whose core benefit is the delivery of information or education (e.g., electronic books, online newspapers, e-learning courses).This book introduces a novel and systematic approach, Product Lines for Digital Information Products (PLANT), which focuses on the creation of variants of such products within a product line, and which extends concepts from the area of software product lines.

Mutation Breeding in Chickpea: Perspectives and Prospects for Food Security

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ISBN: 9788376560717 9783110374254 Year: Pages: 148 DOI: 10.2478/9788376560717 Language: English
Publisher: De Gruyter
Subject: Botany --- Plant Sciences
Added to DOAB on : 2014-11-17 10:29:09
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The book by M. Imran Kozgar aims to cover the problems of mutation breeding in pulse crops in the light of issues related to food insecurity and malnutrition, which according to FAO are the major threats at the present time. So far the research on induction of mutation in pulse crops is negligible compared to cereal crops, though the pulse crops and especially the chickpea are the largest grown crops in India. The main objective of the book is to reveal and explore the possibility of inducing genetic variability in early generations of mutated chickpea, describe the positive aspects of mutagenic treatments, evaluate the content of mineral elements (iron, manganese, zinc and copper) and physiological parameters of isolated high yielding mutant lines. The author hopes that his book will help to advance studies on pulse crops, and that in the long term it will help to reduce the food insecurity and malnutrition problems presently persisting in various developing countries, including India.

Stark Broadening of Spectral Lines in Plasmas

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ISBN: 9783038974550 9783038974567 Year: Pages: 170 DOI: 10.3390/books978-3-03897-456-7 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Mathematics --- Physics (General) --- Nuclear Physics
Added to DOAB on : 2019-01-14 12:59:11
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Experimental and theoretical studies of Stark broadening of spectral lines in plasmas are the cornerstone of a large number of spectroscopic diagnostics of laboratory and astrophysical plasmas. As such, they are very important both fundamentally and practically, the latter being due to the numerous practical applications of plasmas. Examples are studies dealing with: controlled thermonuclear fusion (that would provide a virtually unlimited source of energy), plasma-based lasers for medical and other purposes, technological microwave discharges (especially those used for manufacturing microchips), a better understanding of solar activity, other astrophysical objects (white dwarfs, flare stars, and so on). The book reviews advances in this area achieved in recent years and presents new original papers building on these advances.

Fundamental Approaches to Software Engineering

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Book Series: Lecture Notes in Computer Science; Theoretical Computer Science and General Issues ISBN: 9783030452346 Year: Pages: 552 DOI: 10.1007/978-3-030-45234-6 Language: English
Publisher: Springer Nature
Subject: Computer Science
Added to DOAB on : 2020-05-14 09:29:57
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This open access book constitutes the proceedings of the 23rd International Conference on Fundamental Approaches to Software Engineering, FASE 2020, which took place in Dublin, Ireland, in April 2020, and was held as Part of the European Joint Conferences on Theory and Practice of Software, ETAPS 2020. The 23 full papers, 1 tool paper and 6 testing competition papers presented in this volume were carefully reviewed and selected from 81 submissions. The papers cover topics such as requirements engineering, software architectures, specification, software quality, validation, verification of functional and non-functional properties, model-driven development and model transformation, software processes, security and software evolution.

MicroRNA as Biomarkers in Cancer Diagnostics and Therapy

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ISBN: 9783039212491 9783039212507 Year: Pages: 166 DOI: 10.3390/books978-3-03921-250-7 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Microbiology
Added to DOAB on : 2019-08-28 11:21:27
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This Special Issue celebrates the 25th anniversary of the discovery of the first microRNA. The size of the microRNome and complexity of animal body plans and organ systems suggests a role for microRNAs in cell fate determination and differentiation. More than 2000 sequences have been proposed to represent unique microRNA genes in humans, with an increasing number of mechanistic roles identified in developmental, physiological, and pathological processes. Thus, dysregulation of a few key microRNAs can have a profound global effect on the gene expression and molecular programs of a cell. This great potential for clinical intervention has captured the interest and imagination of researchers in many fields. However, very few fields have been as prolific as the field of cancer research. This Special Issue provides but a glimpse of the large body of literature of microRNA biology in cancer research, containing 4 original research studies and 4 review articles that focus on specific hematologic or solid tumors in disease. Collectively, these articles highlight state-of-the-art approaches and methodologies for microRNA detection in tissue, blood, and other body fluids in a range of biomarkers applications, from early cancer detection to prognosis and treatment response. The articles also address some of the challenges regarding clinical implementation.

3D Remote Sensing Applications in Forest Ecology: Composition, Structure and Function

Authors: ---
ISBN: 9783039217823 9783039217830 Year: Pages: 188 DOI: 10.3390/books978-3-03921-783-0 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Ecology
Added to DOAB on : 2019-12-09 11:49:16
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Dear Colleagues, The composition, structure and function of forest ecosystems are the key features characterizing their ecological properties, and can thus be crucially shaped and changed by various biotic and abiotic factors on multiple spatial scales. The magnitude and extent of these changes in recent decades calls for enhanced mitigation and adaption measures. Remote sensing data and methods are the main complementary sources of up-to-date synoptic and objective information of forest ecology. Due to the inherent 3D nature of forest ecosystems, the analysis of 3D sources of remote sensing data is considered to be most appropriate for recreating the forest’s compositional, structural and functional dynamics. In this Special Issue of Forests, we published a set of state-of-the-art scientific works including experimental studies, methodological developments and model validations, all dealing with the general topic of 3D remote sensing-assisted applications in forest ecology. We showed applications in forest ecology from a broad collection of method and sensor combinations, including fusion schemes. All in all, the studies and their focuses are as broad as a forest’s ecology or the field of remote sensing and, thus, reflect the very diverse usages and directions toward which future research and practice will be directed.

Cognitive Aspects of Human-Computer Interaction for GIS

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ISBN: 9783039215683 9783039215690 Year: Pages: 196 DOI: 10.3390/books978-3-03921-569-0 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Computer Science
Added to DOAB on : 2019-12-09 16:10:12
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The book is dealing with recent progress in human–computer interaction (HCI) related to geographic information science (GIS). The Editorial starts with an overview about the evolution of the Internet and first HCI concepts and stimulates recent HCI developments using 3D and 4D apps, running on all mobile devices with OS Android, iOS, Linus, and Windows. Eight research articles present the state-of-the-art in HCI–GIS-related issues, starting with gender and age differences in using indoor maps via the estimation of building heights from space to an efficient visualization method for polygonal data with dynamic simplification. The review article deals with progress and challenges on entity alignment of geographic knowledge bases.

Systems Analytics and Integration of Big Omics Data

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ISBN: 9783039287444 / 9783039287451 Year: Pages: 202 DOI: 10.3390/books978-3-03928-745-1 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2020-06-09 16:38:57
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A “genotype"" is essentially an organism's full hereditary information which is obtained from its parents. A ""phenotype"" is an organism's actual observed physical and behavioral properties. These may include traits such as morphology, size, height, eye color, metabolism, etc. One of the pressing challenges in computational and systems biology is genotype-to-phenotype prediction. This is challenging given the amount of data generated by modern Omics technologies. This “Big Data” is so large and complex that traditional data processing applications are not up to the task. Challenges arise in collection, analysis, mining, sharing, transfer, visualization, archiving, and integration of these data. In this Special Issue, there is a focus on the systems-level analysis of Omics data, recent developments in gene ontology annotation, and advances in biological pathways and network biology. The integration of Omics data with clinical and biomedical data using machine learning is explored. This Special Issue covers new methodologies in the context of gene–environment interactions, tissue-specific gene expression, and how external factors or host genetics impact the microbiome.

Keywords

tissue-specific expressed genes --- transcriptome --- tissue classification --- support vector machine --- feature selection --- bioinformatics pipelines --- algorithm development for network integration --- miRNA–gene expression networks --- multiomics integration --- network topology analysis --- candidate genes --- gene–environment interactions --- logic forest --- systemic lupus erythematosus --- Gene Ontology --- KEGG pathways --- enrichment analysis --- proteomic analysis --- plot visualization --- Alzheimer’s disease --- dementia --- cognitive impairment --- neurodegeneration --- Gene Ontology --- annotation --- biocuration --- amyloid-beta --- microtubule-associated protein tau --- artificial intelligence --- genotype --- phenotype --- deep phenotype --- data integration --- genomics --- phenomics --- precision medicine informatics --- epigenetics --- chromatin modification --- sequencing --- regulatory genomics --- disease variants --- machine learning --- multi-omics --- data integration --- curse of dimensionality --- heterogeneous data --- missing data --- class imbalance --- scalability --- genomics --- pharmacogenomics --- cell lines --- database --- drug sensitivity --- data integration --- omics data --- genomics --- RNA expression --- non-omics data --- clinical data --- epidemiological data --- challenges --- integrative analytics --- joint modeling --- multivariate analysis --- multivariate causal mediation --- distance correlation --- direct effect --- indirect effect --- causal inference --- n/a

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