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Alternatives to Antimicrobial Growth Promoters and Their Impact in Gut Microbiota, Health and Disease

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889453757 Year: Pages: 92 DOI: 10.3389/978-2-88945-375-7 Language: English
Publisher: Frontiers Media SA
Subject: Medicine (General) --- Animal Sciences
Added to DOAB on : 2018-11-16 17:17:57
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In the context of disease pathogenesis, it has been observed that after inadequate administration of antibiotics, animals become more susceptible to intestinal colonization and organ invasion by enteropathogens, these could be related to changes caused in the gastrointestinal microbial community. Therefore, we must reconsider the negative consequences that disruption of the microbiome has in the biology of metazoans (dysbacteriosis). Alternations of the intestinal microbiota composition in animals can be caused by multiple factors, including the misuse of antibiotics, having as a result a negative impact on the development and function of the immune, endocrine, nervous, and digestive systems. For this reason, social concerns regarding the development of antibiotic-resistant microorganisms have resulted in an urgent necessity to find feasible alternatives to maintain animal health and performance without the use of antibiotic growth promoters (AGP), in order to sustain livestock production as an economically viable source of food for human consumption. Hence, research about AGP alternatives such as probiotics, prebiotics, phytochemicals, organic acids, enzymes, and vaccines has become a priority for many scientists around the world.

Low-dose antibiotics: current status and outlook for the future

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889193554 Year: Pages: 167 DOI: 10.3389/978-2-88919-355-4 Language: English
Publisher: Frontiers Media SA
Subject: Microbiology --- Science (General)
Added to DOAB on : 2016-03-10 08:14:32
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Antimicrobial therapy is a key factor in our success against pathogens poised to ravage at risk or infected individuals. However, we are currently at a watershed point as we face a growing crisis of antibiotic resistance among diverse pathogens. One area of intense interest is the impact of the application of antibiotics for uses other than the treatment of patients and the association with such utilization with emerging drug resistance. This Research Topic “Low- dose antibiotics: current status and outlook for the future” in Frontiers in Microbiology: Antimicrobials, Resistance and Chemotherapy details various aspects of the wide ranging effects of antimicrobial therapy from areas such as the regulation of host responses to modulation of bacterial virulence factors to acquisition of antibiotic resistance genes.

Environmentally Sustainable Livestock Production

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ISBN: 9783038975526 9783038975533 Year: Pages: 290 DOI: 10.3390/books978-3-03897-553-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Environmental Sciences --- Social Sciences
Added to DOAB on : 2019-01-25 10:30:03
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This book looks at key research covering a wide range of aspects of environmental sustainability and the mitigation of environmental impacts of livestock production, including emissions of greenhouse gases (carbon dioxide, methane, nitrous oxide), nitrogen and phosphorus excretion, ammonia emissions, land use and land management, and use of energy and other resources. All the globally most important livestock species (beef and dairy cattle, pigs, broiler chicken and laying hens) are covered in the book. The mitigation methods assessed in the papers include general system changes, changes in feeding, improvement of animal health, and new technologies of manure management. The scope of the papers included in this book ranges from farm level mitigation methods to national level system changes. This book also addresses methodological development in assessing the environmental sustainability of the livestock production chains, including holistic methods, such as environmental and social life cycle assessment (LCA) and other modeling approaches.

Legumes in Cropping Systems

Authors: --- ---
ISBN: 9781780644981; 9781780646749; 9781780646756 Year: Pages: 256 Language: English
Publisher: CABI
Subject: Agriculture (General) --- Plant Sciences
Added to DOAB on : 2020-10-16 15:38:09
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This book is a contribution to the debate and knowledge for the rebalancing of farming and food using legumes. The main aim is to help people who are involved in developing cropping systems: the decision makers of today and today's students who are the decision makers of tomorrow. It is aimed at all relevant decision makers: farmers, professionals who support innovation in farming, and the policy community in its widest sense. It contains 13 chapters describing various aspects of the use of legumes (including grain and feed legumes) in European cropping systems. Each chapter provides deep insight into the relevant literature to support understanding rather than a comprehensive academic review. The aim is to empower the reader with insights and understanding of the underlying processes that influence cropping system development.

Horse Feeding and Management

Authors: --- ---
ISBN: 9783039285525 / 9783039285532 Year: Pages: 195 DOI: 10.3390/books978-3-03928-553-2 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Nutrition and Food Sciences
Added to DOAB on : 2020-06-09 16:38:57
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Horses perform variety of roles in our society, serving people in several ways. Proper nutrition and feeding management are some of the main objectives to ensure the well-being and performance of horses. Thus, the link between equine health and good dietary treatment must be recognized to increase our understanding of the needs of the horse. It is important to ensure science-based knowledge is available to all stakeholders and people working in the horse industry. This book presents research papers published in the Special Issue of Animals entitled ‘Horse Nutrition and Management’.

Effects of Mycotoxins on the Intestine

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ISBN: 9783038977827 9783038977834 Year: Pages: 262 DOI: 10.3390/books978-3-03897-783-4 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Public Health
Added to DOAB on : 2019-05-09 17:16:14
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Mycotoxins are secondary metabolites produced by several fungal species. They can contaminate human food and animal feed, and have been a threat for thousands of years. The gastrointestinal tract is the first target when ingesting mycotoxin-contaminated food or feed. As unlikely as it sounds, the investigations concerning the effects of mycotoxins on the intestine are still in their early stages. This book gathers the most recent advances related to the characterization of the intestinal toxicity of mycotoxins. Substantial data assembled on the damage caused to a number of histological structures and functions of the intestine remove any remaining doubt about this organ being a primary target for the toxicity of mycotoxins. An interesting overview of the detrimental effects of mycotoxins on the gut-hosted microbiota&mdash;now regarded as a fully-fledged organ associated with the gut&mdash;is also given. Finally, outstanding contributions in this book address questions relating to the suitability of current regulations to protect against alterations of the intestine, and to the efficacy assessment of new detoxification strategies using the intestinal toxicity of mycotoxins as a relevant endpoint.

Keywords

mice --- aflatoxin B1 --- intestinal bacterial flora --- response --- Clostridium sp. WJ06 --- deoxynivalenol --- pig --- intestinal morphology --- microbial diversity --- aflatoxin M1 --- ochratoxin A --- intestinal epithelial cells --- tight junction --- permeability --- ileum --- jejunum --- deoxynivalenol --- piglet --- contaminated feed --- tight junction --- aflatoxin B1 --- small intestine --- histopathological lesions --- ultrastructural changes --- toll-like receptors --- T-2 toxin --- enteric nervous system --- pig --- vasoactive intestinal polypeptide --- mycotoxins --- zearalenone --- deoxynivalenol --- histology --- ultrastructure --- large intestine --- pig --- Claviceps --- liver --- digestive tract --- mycotoxin --- sclerotia --- ergot alkaloids --- toxicity --- deoxynivalenol --- Saccharomyces cerevisiae boulardii CNCM I-1079 --- intestine --- transcriptome --- inflammation --- oxidative stress --- lipid metabolism --- fumonisin --- microbiota --- pigs --- MiSeq 16S rDNA sequencing --- intestinal microbiota --- hydrogen-rich water --- lactulose --- Fusarium mycotoxins --- piglets --- functional oligosaccharides --- mycotoxins --- swine --- explant technique --- intestinal morphology --- goblet cells --- deoxynivalenol --- zearalenone --- pig --- colon microbiota --- Lactobacillus --- detoxification --- zearalenone --- doses --- caecal water --- genotoxicity --- pre-pubertal gilts --- atlantic salmon --- deoxynivalenol --- feed --- intestine --- PCR --- proliferating cell nuclear antigen --- suppressor of cytokine signaling --- tight junctions --- Zearalenone --- N-acetylcysteine --- SIEC02 cells --- Mitochondrial apoptosis --- n/a

Welfare of Cultured and Experimental Fishes

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ISBN: 9783039217106 9783039217113 Year: Pages: 132 DOI: 10.3390/books978-3-03921-711-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Animal Sciences
Added to DOAB on : 2019-12-09 11:49:16
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Welfare is a multidimensional concept that can be described as the state of an animal as it copes with the environment. Captive environments can impact farmed animals at different levels, especially fishes, considering their highly complex sensory world. Understanding the ethology of a species is therefore essential to address fish welfare, and the interpretation of behavioral responses in specific rearing contexts (aquaculture or experimental contexts) demands knowledge of their underlying physiological, developmental, functional, and evolutionary mechanisms. In natural environments, the stress response has evolved to help animals survive challenging conditions. However, animals are adapted to deal with natural stressors, while anthropogenic stimuli may represent stressors that fishes are unable to cope with. Under such circumstances, stress responses may be maladaptive and cause severe damage to the animal. As welfare in captivity is affected in multiple dimensions, multiple possible indicators can be used to assess the welfare state of individuals. In the past, research on welfare has been largely focusing on health indicators and predominantly based on physiological stress. Ethological indicators, however, also integrate the mental perspective of the individual and have been gradually assuming an important role in welfare research: behavioral responses to stressors are an early response to adverse conditions, easily observable, and demonstrative of emotional states. Many behavioral indicators can be used as non-invasive measurements of welfare in practical contexts such as aquaculture and experimentation. Presently, research in fish welfare is growing in importance and interest because of the growing economic importance of fish farming, the comparative biology opportunities that experimental fishes provide, and the increasing public sensitivity to welfare issues.

Quality and Production of Forage

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ISBN: 9783039216741 9783039216758 Year: Pages: 148 DOI: 10.3390/books978-3-03921-675-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Agriculture (General)
Added to DOAB on : 2019-12-09 11:49:16
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The book ""Quality and Production of Forage"" is intended to keep readers updatedon the developments occurring in this field. As it is apparent that livestockanimals are important throughout the world because of the meat, milk and eggthey produce, knowledge about the forages available to animals must also beconsidered for increased production, quality and efficiency. This book providesinformation that readers will find considerably invaluable about forage feeds, suchas grass, legumes, and straw. The book is composed of ten papers, focusing on awide range of research activities and topics that feature the following concepts offorage: the effect of conservation method on forage protein value; Microbial thecomposition and mycotoxin content in forage; genetic diversity of forages; timelysowing to maximize yield for both grain and biomass; ensiling treatments onforage quality; the qualitative characteristics of different accessions of new foragespecies; forage policy influencing feed costs; feeding forage on animal health;high-protein tropical forages as alternative sources for poultry; impact of foragesin poultry diet and significance of forages in sustainable poultry productionsystems. This book will be an invaluable reference for students and professionalsin agricultural science and grassland and animal husbandry researches.

Biogenic Amines on Food Safety

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ISBN: 9783039210541 9783039210558 Year: Pages: 202 DOI: 10.3390/books978-3-03921-055-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2019-08-28 11:21:27
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Biogenic amines have been known for some time. These compounds are found in varying concentrations in a wide range of foods (fish, cheese, meat, wine, beer, vegetables, etc.) and their formations are influenced by different factors associated to those foods (composition, additives, ingredients, storage, microorganism, packaging, handing, conservation, etc.). The intake of foods containing high concentrations of biogenic amines can present a health hazard. Additionally, they have been used to establish indexes in various foods in order to signal the degree of freshness and/or deterioration of food. Nowadays, there has been an increase in the number of food poisoning episodes in consumers associated with the presence of these biogenic amines, mainly associated with histamines. Food safety is one of the main concerns of the consumer and safety agencies of different countries (EFSA, FDA, FSCJ, etc.), which have, as one of their main objectives, to control these biogenic amines, principally histamine, to assure a high level of food safety.Therefore, it is necessary to deepen our understanding of the formation, monitoring and reduction of biogenic amines during the development, processing and storage of food, even the effect of biogenic amines in consumers after digestion of foods with different levels of these compounds.With this aim, we are preparing a Special Issue on the topic of ""Biogenic Amines in Food Safety"", and we invite researchers to contribute original and unpublished research articles and reviews articles that involve studies of biogenic amines in food, which can provide an update to our knowledge of these compounds and their impacts on food quality and food safety.

Carotenoids

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ISBN: 9783039218646 9783039218653 Year: Pages: 168 DOI: 10.3390/books978-3-03921-865-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2020-01-07 09:08:26
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Carotenoids are a group of natural pigments, consisting of more than 750 compounds. They are mostly yellow, orange, or red in color, due to the system of conjugated double bonds. This structural element is also responsible for the good antioxidant properties of many carotenoids. Carotenoids have shown numerous biological activities (not only as provitamin A), e.g., preventive properties of fruits and vegetables. As lipophilic compounds, their uptake and storage in the body are dependent on various conditions. In vitro and in vivo data showed stimulating and inhibitory effects of matrix compounds on bioaccessibility and bioavailability of carotenoids.

Keywords

?-carotene --- lycopene --- antioxidants --- free radicals --- ageing --- fruit --- vegetables --- ?-carotene --- HIV --- nelfinavir --- interaction --- pharmacokinetics --- carotenoids --- astaxanthin --- oxidative stress --- antioxidant --- chelating compound --- metal ions --- antireductant --- antiradical --- cationic lipid --- carotenoid --- antisense oligonucleotide --- exon skipping --- Duchenne muscular dystrophy --- ?-carotene --- lutein --- chlorophyll --- spent coffee grounds --- soil amendment --- lettuce --- accelerated solvent extraction --- pressurized fluid extraction --- ethanol --- carrots --- ?-carotene --- antioxidants --- marine carotenoids --- inflammation --- oxidative stress --- cardiovascular disease --- flavonoids --- carotenoids --- antioxidant synergism --- antioxidant antagonism --- free radical kinetics --- dye-sensitized solar cells --- carotenoid and chlorophyll derivatives --- singlet-triplet annihilation --- carotenoids --- xanthophylls --- fluorocarotenoids --- chlorocarotenoids --- bromocarotenoids --- iodocarotenoids --- silicon carotenoids --- nitrogen carotenoids --- sulfur carotenoids --- selenium carotenoids --- iron carotenoids --- carotenoids --- xanthophylls --- cancer chemoprevention --- mechanisms --- B16F10 --- ?-carotene --- PC-3 --- SK-Hep-1 --- VEGF --- oxidative stress --- ROS --- RNS --- antioxidants --- carotenoids --- cardiovascular disease --- carotenoids --- hydrophilic --- esterification --- PEG conjugates --- cycloaddition --- carotenoid --- stability --- feed processing --- storage --- carotenoids --- extraction --- solubility --- injection solvent --- liquid chromatography

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