Search results: Found 4

Listing 1 - 4 of 4
Sort by
Sex Hormone Receptor Signals in Human Malignancies

Author:
ISBN: 9783039211739 9783039211746 Year: Pages: 152 DOI: 10.3390/books978-3-03921-174-6 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2019-12-09 11:49:15
License:

Loading...
Export citation

Choose an application

Abstract

Sex steroids, including androgens, estrogens, and progestogens, are knownto have widespread physiological actions beyond the reproductive systemvia binding to the sex hormone receptors. Meanwhile, emerging evidence hasindicated that sex hormone receptor signals are involved in the outgrowth ofsome malignancies, such as prostate and breast carcinomas, as well as othersthat have not traditionally been considered as endocrine-related neoplasms. ThisSpecial Issue “Sex Hormone Receptor Signals in Human Malignancies” coversvarious aspects of the potential role of sex hormone receptors and related signalsin prostate cancer, breast cancer, and other neoplastic conditions by depictingpromising findings derived from in vitro and in vivo experiments as well as theanalyses of surgical specimens. The current observations described may thusprovide a unique insight into novel or known functions of sex hormone receptorsand related molecules.

Mechanisms of Adiponectin Action

Author:
ISBN: 9783039212453 9783039212460 Year: Pages: 222 DOI: 10.3390/books978-3-03921-246-0 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Social Sciences --- Sociology
Added to DOAB on : 2019-08-28 11:21:27
License:

Loading...
Export citation

Choose an application

Abstract

The adipokine adiponectin is very concentrated in plasma, and decreased levels of adiponectin are associated with pathological conditions such as obesity, diabetes, cardiovascular diseases, and metabolic syndrome. When produced in its full-length form, adiponectin self-associates to generate multimeric complexes. The full-length form of adiponectin can be cleaved by the globular form of elastase that is produced locally, and the resulting biological effects are exerted in a paracrine or autocrine manner. The different forms of adiponectin bind to specific receptors consisting of two G-protein-independent, seven-transmembrane-spanning receptors, called AdipoR1 and AdipoR2, while T-cadherin has been identified as a potential receptor for high molecular weight complexes of adiponectin. Adiponectin exerts a key role in cellular metabolism, regulating glucose levels as well as fatty acid breakdown. However, its biological effects are heterogeneous, involving multiple target tissues. The Special Issue “Mechanisms of Adiponectin Action” highlights the pleiotropic role of this hormone through 3 research articles and 7 reviews. These papers focus on the recent knowledge regarding adiponectin in different target tissues, both in healthy and in diseased conditions.

Novel Approaches to Minimising Mycotoxin Contamination

Authors: ---
ISBN: 9783039289370 / 9783039289387 Year: Pages: 244 DOI: 10.3390/books978-3-03928-938-7 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Public Health
Added to DOAB on : 2020-06-09 16:38:57
License:

Loading...
Export citation

Choose an application

Abstract

Contamination of foods and agricultural commodities by various types of toxigenic fungi is a concerning issue for human and animal health. Moulds naturally present in foods can produce mycotoxins and contaminate foodstuffs under favourable conditions of temperature, relative humidity, pH, and nutrient availability. Mycotoxins are, in general, stable molecules that are difficult to remove from foods once they have been produced. Therefore, the prevention of mycotoxin contamination is one of the main goals of the agriculture and food industries. Chemical control or decontamination techniques may be quite efficient; however, the more sustainable and restricted use of fungicides, the lack of efficiency in some foods, and the consumer demand for chemical-residue-free foods require new approaches to control this hazard. Therefore, food safety demands continued research efforts for exploring new strategies to reduce mycotoxin contamination. This Special Issue contains original contributions and reviews that advance the knowledge about the most current promising approaches to minimize mycotoxin contamination, including biological control agents, phytochemical antifungal compounds, enzyme detoxification, and the use of novel technologies.

Keywords

deoxynivalenol --- degradation --- photocatalysis --- ?-Fe2O3 --- degradation products --- Aspergillus flavus --- Penicillium verrucosum --- AITC --- fungal growth reduction --- mycotoxin reduction --- decontamination --- mycotoxins --- Aflatoxin M1 --- milk --- binding --- stability --- zearalenone --- biological detoxification --- Bacillus --- fermentation --- roasted coffee --- mycotoxigenic fungi --- ochratoxin A --- cold plasma --- detoxification --- brine shrimp bioassay --- mycotoxins --- Fusarium sp., Botrytis sp., apple pomace --- phloridzin --- quercetin glycosides --- pinnatifidanoside D --- deoxynivalenol --- wheat --- superheated steam --- wheat quality --- crisp biscuit --- biological control --- post-harvest phytopathogen --- Penicillium digitatum --- Penicillium italicum --- Geothrichum citri-aurantii --- zearalenone --- estrogen response element --- gene expression --- cell proliferation --- estrogen receptor --- biotransformation --- Fusarium --- mycotoxins --- garlic-derived extracts --- green chemistry --- fungi --- EU limits --- abiotic factors --- storage --- wheat --- maize --- oats --- fumonisin --- enzymatic detoxification --- fumonisin esterase FumD --- enzyme kinetics --- maize --- Zearalenone --- biodegradation --- probiotics --- cell-free extracts of Aspergillus oryzae --- pig production performance --- Bacillus --- Fusarium graminearum --- antagonism --- mode of action --- essential oils --- Satureja montana --- Origanum virens --- Aspergillus flavus --- aflatoxin --- corn --- nanoparticles --- Penicillium nordicum --- biocontrol agents --- dry-cured ham --- ochratoxin A (OTA) --- n/a

Promising Detoxification Strategies to Mitigate Mycotoxins in Food and Feed

Author:
ISBN: 9783038970286 9783038970279 Year: Pages: 306 DOI: 10.3390/books978-3-03897-027-9 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Public Health
Added to DOAB on : 2019-08-28 11:21:28
License:

Loading...
Export citation

Choose an application

Abstract

This book is a printed edition of the Special Issue Promising Detoxification Strategies to Mitigate Mycotoxins in Food and Feed that was published in Toxins

Keywords

deoxynivalenol --- epimer --- polarity --- Tri101 --- molecular --- interactions --- spores of Ganoderma lucidum --- oxidative stress --- aflatoxins --- antioxidant capability --- mycotoxin --- patulin --- biodegradation --- Pichia caribbica --- proteomics --- intracellular and extracellular enzymes --- Bacillus licheniformis CK1 --- zearalenone (ZEA) --- serum hormones --- estrogen receptor (ER) --- post-weaning female piglets --- curcumin --- aflatoxin B1 --- CYP450 --- AFBO–DNA --- chicks --- aflatoxin B1 --- photodegradation product --- TQEF-MS/MS --- cell viability --- furan rings --- mycotoxin --- toxigenic Fusarium --- biological control --- Trichoderma --- modified mycotoxin --- aflatoxin B1 --- aflatoxin biodegradation preparation --- Bacillus subtilis ANSB060 --- ameliorating effects --- growth performance --- antioxidant function --- residue --- aflatoxins --- biotransformation --- enzymatic detoxification --- laccase --- mild technologies --- food safety --- mycotoxins mitigation --- aflatoxin B1 --- aflatoxin-degrading enzyme --- biodegradation --- Bacillus shackletonii --- purification --- Sporobolomyces sp. IAM 13481 --- microbial patulin degradation --- desoxypatulinic acid --- ascladiol --- aflatoxins --- Aspergillus flavus --- Corylus avellana --- fatty acids --- thermal treatment --- Aflatoxin B1 --- Aspergillus flavus --- hyssop --- inhibition --- oxidative stress --- DBD --- atmospheric pressure --- low temperature plasma --- mycotoxins --- degradation --- maize --- aflatoxins --- neutral electrolyzed water --- detoxification --- turkey --- mycotoxins --- biotransformation --- degradation --- enzymes --- application --- mycotoxin --- detoxification --- biodegradation --- biotransformation --- enzyme --- microorganism identification --- mycotoxin --- trichothecene --- deoxynivalenol --- bioprospecting --- detoxification --- Fusarium --- cold atmospheric pressure plasma technology --- mycotoxins --- physical decontamination --- chemical decontamination --- biological decontamination --- patulin --- mycotoxin --- mitigation --- decontamination --- food and beverage --- processing --- n/a

Listing 1 - 4 of 4
Sort by
Narrow your search

Publisher

MDPI - Multidisciplinary Digital Publishing Institute (4)


License

CC by-nc-nd (4)


Language

english (3)

eng (1)


Year
From To Submit

2020 (1)

2019 (2)

2018 (1)