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Prozessintensivierung durch feldunterstützte Bioseparation : Elektrofiltration und in situ Magnetseparation

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ISBN: 9783866443051 Year: Pages: 205 p. DOI: 10.5445/KSP/1000009764 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Chemical Engineering
Added to DOAB on : 2019-07-30 20:02:02
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Die Bioseparation ist mitunter der kostenintensivste Teil der Bioproduktion. Daher sind Technologien nötig, die das Downstream processing vereinfachen. Die Magnetseparation und die Elektrofiltration sind Methoden, die durch externe Felder einen Trennschritt verbessern und somit die Raum-Zeit-Ausbeute des Verfahrensschritts erhöhen können. Die Anwendung der Magnetseparation als in situ Separationsmethode und der Elektrofiltration als Proteinfraktionierungstechnik wird in dieser Arbeit erörtert.

Carboxylic Acid Production

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ISBN: 9783038425526 9783038425533 Year: Pages: 174 DOI: 10.3390/books978-3-03842-553-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology
Added to DOAB on : 2018-01-04 15:30:04
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Carboxylic acids are truly central compounds in cellular metabolism. Carbon dioxide is captured from the atmosphere through formation of carboxylic groups and is also released, in part, by decarboxylation reactions. The reactivity of the carboxylic group with amino- or hydroxyl-groups enables the formation of peptide and ester bonds. The functionality of the carboxylic group is also of huge importance in our industrial world for a wide range of applications. The loosely bound hydrogen provides weak acid functionality, much desired for food industry applications in preservatives and flavour compounds. Citric acid is one of our oldest industrial fermentation products. The presence of two carboxylic groups, or a combination of one carboxylic group and another functional group, make the compounds interesting building blocks for polymer production. A number of carboxylic acids, including, e.g., lactic, succinic, 3-hydroxypropionic and itaconic acids, have been identified and recognized as suitable platform chemicals for a foreseen growing carbohydrate based economy. Economic margins are, however, tight when competing with petroleum based production, and production strains, fermentation technology and—not least—downstream processing, all need to be improved to enable viable commercial production.This Special issue will cover current developments within this exciting field. Topics will include: Fermentation physiology of natural carboxylic acid producers; screening and isolation of novel producers; metabolic engineering for improving intrinsic carboxylic acid production; metabolic engineering for expanding product range to non-endogenous carboxylic acids; production from lignocellulosic derived sugars or by-product streams; downstream processing for recovery of carboxylic acids; bioprocess design—including continuous processes and integration.All production organisms—fungi, yeasts, bacteria—are welcome.

Advances in Polyhydroxyalkanoate (PHA) Production, Volume 2

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ISBN: 9783039286409 / 9783039286416 Year: Pages: 202 DOI: 10.3390/books978-3-03928-641-6 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- Biotechnology
Added to DOAB on : 2020-06-09 16:38:57
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Nowadays, we are witnessing highly dynamic research activities related to the intriguing field of biodegradable materials with plastic-like properties. These activities are stimulated by the strengthened public awareness of prevailing ecological issues connected to growing piles of plastic waste and increasing greenhouse gas emissions; this goes hand-in-hand with the ongoing depletion of fossil feedstocks, which are traditionally used to produce full carbon backbone polymers. Polyhydroxyalkanoate (PHA) biopolyesters, a family of plastic-like materials with versatile material properties, are increasing considered to be a future-oriented solution for diminishing these concerns. PHA production is based on renewable resources and occurs in a bio-mediated fashion through the action of living organisms. If accomplished in an optimized way, PHA production and the entire PHA lifecycle are embedded into nature´s closed cycles of carbon. Sustainable and efficient PHA production requires understanding and improvement of all the individual process steps. Holistic improvement of PHA production, applicable on an industrially relevant scale, calls for, inter alia, consolidated knowledge about the enzymatic and genetic particularities of PHA-accumulating organisms, an in-depth understanding of the kinetics of the bioprocess, the selection of appropriate inexpensive fermentation feedstocks, tailoring of PHA composition at the level of its monomeric constituents, optimized biotechnological engineering, and novel strategies for PHA recovery from biomass characterized by low energy and chemical requirements. This Special Issue represents a comprehensive compilation of articles in which these individual aspects have been addressed by globally recognized experts.

Keywords

polyhydroxyalkanoate (PHA), bioprocess design --- carbon dioxide --- cyanobacteria --- upstream processing --- Archaea --- bioeconomy --- biopolyester --- downstream processing --- extremophiles --- haloarchaea --- Haloferax --- halophiles --- polyhydroxyalkanoates --- salinity --- polyhydroxyalkanoates --- terpolymer --- P(3HB-co-3HV-co-4HB) --- Cupriavidus malaysiensis --- polyhydroxyalkanoates --- biomedicine --- biomaterials --- Poly(3-hydroxybutyrate) --- tissue engineering --- wound healing --- delivery system --- poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHVB) --- poly(3-hydroxybutyrate-co-4-hydroxybutyrate) --- bubble column bioreactor --- COMSOL --- microorganism --- PHB --- simulation --- polyhydroxyalkanoate --- PHA --- process analytical technologies --- PAT --- plant oil --- high-cell-density fed-batch --- photon density wave spectroscopy --- PDW --- Ralstonia eutropha --- Cupriavidus necator --- on-line --- in-line --- polyhydroxyalkanoates --- fed-batch --- productivity --- Pseudomonas --- bioreactor --- microaerophilic --- PHA --- viscosity --- non-Newtonian fluid --- fed-batch fermentation --- oxygen transfer --- Pseudomonas putida --- medium-chain-length polyhydroxyalkanoate (mcl-PHA) --- alginate --- biosurfactants --- biopolymer --- Pseudomonas --- blends --- film --- polyhydroxyalkanoates processing --- electrospinning --- additive manufacturing --- selective laser sintering --- fused deposition modeling --- computer-aided wet-spinning --- polyhydroxybutyrate --- tequila bagasse --- hydrolysate detoxification --- activated charcoal --- phenolic compounds --- biomedical application --- cyanobacteria --- feedstocks --- gaseous substrates --- haloarchaea --- high cell density cultivation --- in-line monitoring --- PHA composition --- PHA processing --- polyhydroxyalkanoate --- process engineering --- process simulation --- Pseudomonas sp. --- rheology --- terpolyester --- waste streams

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