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Forschungsdatenmanagement sozialwissenschaftlicher Umfragedaten

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ISBN: 9783847412601 9783847422334 Year: Pages: 233 DOI: 10.3224/84742233 Language: German
Publisher: Verlag Barbara Budrich
Subject: Sociology
Added to DOAB on : 2019-03-22 11:21:02
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The book is based on practical requirements for the management of quantitative research data in small to medium-sized research projects in the social sciences, which generate and analyse data, save original data and archive and make them available for further use in the long term. In order to equip scientists with the tools to specifically meet these requirements, typical questions of data-based research projects are addressed on the basis of application cases and systematically processed with proven concepts of research data management. Overall, the book is a practical guide to documenting data-based research products (e.g. data files, measuring instruments, survey methods, analysis syntaxes) step by step, securing them professionally and making them available for subsequent use. In addition, the book highlights open questions and current challenges in dealing with research data. In the interest of scientifically and methodologically sound research data management, it also opens up perspectives for university education and research into the management of research data.

Drug Repositioning: Current Advances and Future Perspectives

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889456963 Year: Pages: 153 DOI: 10.3389/978-2-88945-696-3 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Therapeutics
Added to DOAB on : 2019-01-23 14:53:43
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Drug repositioning is the process of identifying new indications for existing drugs. At present, the conventional de novo drug discovery process requires an average of about 14 years and US$2.5 billion to approve and launch a drug. Drug repositioning can reduce the time and cost of this process because it takes advantage of drugs already in clinical use for other indications or drugs that have cleared phase I safety trials but have failed to show efficacy in the intended diseases. Historically, drug repositioning has been realized through serendipitous clinical observations or improved understanding of disease mechanisms. However, recent technological advances have enabled a more systematic approach to drug repositioning. This eBook collects 16 articles from 112 authors, providing readers with current advances and future perspectives of drug repositioning.

Ouvrir, partager, réutiliser : Regards critiques sur les données numériques

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ISBN: 9782735123865 DOI: 10.4000/books.editionsmsh.9026 Language: French
Publisher: Éditions de la Maison des sciences de l’homme
Subject: Social Sciences
Added to DOAB on : 2019-12-10 12:25:07
License: OpenEdition Licence for Books

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On assiste actuellement à la multiplication des données numériques provenant de diverses sources : les administrations mettent en ligne leurs données de fonctionnement dans le cadre de démarches open data, les entreprises ouvrent certaines de leurs données non stratégiques, le monde scientifique utilise des données hétérogènes et de grande taille, et les internautes produisent des données à travers leurs activités quotidiennes sur le web. Loin d’être simplement mises en ligne, ces données sont « mises à disposition » des utilisateurs en vue de créer de nouveaux services et d’améliorer la connaissance des pratiques sociales. Comme le montre les discours d’accompagnement produits par les différents acteurs, les espoirs placés dans les données numériques sont nombreux et les transformations annoncées sont bien souvent présentées comme inéluctable et par défaut source de progrès. Loin de considérer cet « impératif d’ouverture » comme immuable, l’ambition du présent ouvrage est d’interroger de manière critique les multiples processus sociotechniques au sein desquels les données s’insèrent, de leur production à leur usage. Cette démarche propose d’ouvrir des pistes de réflexions pour mieux appréhender les évolutions de notre environnement numérique.

Diagnosis and Management of Pediatric Diseases

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ISBN: 9783039219667 / 9783039219674 Year: Pages: 146 DOI: 10.3390/books978-3-03921-967-4 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General)
Added to DOAB on : 2020-01-07 09:08:26
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A screenshot of some the most rapidly evolving fields in Neonatology and Pediatrics with articles reviewing some metabolic dysregulations as well as non-oncologic diseases that may occur in infancy, childhood, youth. The illustrative material with original photographs and drawings highlighting some pathogenetic concepts are keystones of this book.

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