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On Relativization and Clefting. An Analysis of Italian Sign Language

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Book Series: Sign Languages and Deaf Communities [SLDC] ISSN: 2192-516X ISBN: 9781501500008 Year: Volume: 5 Pages: 360 DOI: 10.1515/9781501500008 Language: English
Publisher: De Gruyter
Subject: Linguistics
Added to DOAB on : 2018-12-19 16:52:49
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Abstract

This work is a contribution to our understanding of relativization strategies and clefting in Italian Sign Language, and more broadly, to our understanding of these constructions in world languages by setting the discussion on the theories that have been proposed in the literature of spoken languages to derive the syntactic phenomena object of investigation.

Turbulence in River and Maritime Hydraulics

Authors: --- ---
ISBN: 9783038975946 Year: Pages: 296 DOI: 10.3390/books978-3-03897-595-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: General and Civil Engineering --- Technology (General)
Added to DOAB on : 2019-03-21 15:50:41
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Understanding of the role of turbulence in controlling transport processes is of paramount importance for the preservation and protection of aquatic ecosystems, the minimization of the deleterious consequences of anthropogenic activity, and the successful sustainable development of river and maritime areas. In this context, the present Special Issue collects 15 papers which provide a representation of the present understanding of turbulent processes and their effects in river and maritime environments. The presented collection of papers is not exhaustive, but it highlights the key priority areas and knowledge gaps in this field of research. The published papers present the state-of-the-art knowledge of complex environmental flows which are useful for researchers and practitioners. The paper contents are an overview of some recent topics of research and an exposure of the current and future challenges associated with these topics.

Keywords

breaking waves --- turbulence invariants --- laboratory experiments --- flow-through system --- tidal inlets --- residence time --- coastal lagoon --- MIKE 3 FM (HD & --- TR) --- MIKE 21 FM (HD) --- dense jet --- current flow --- velocity --- trajectory --- turbulence --- dissipation --- rivers --- meanders --- turbulence --- secondary motion --- prediction --- bedrock canyon --- ADCP --- eddy viscosity --- bed shear stress --- spatial analysis --- smoothed particle hydrodynamics models --- physical modelling --- plunging breaking waves --- vorticity --- turbulent jet --- wave–current interaction --- spectral dissipation --- bottom friction --- numerical model --- hydrodynamic model --- spectral model --- wave attenuation --- energy dissipation --- drag coefficient --- flexible vegetation --- Spartina maritima --- vegetation patch --- wake region --- submerged ratio --- SVF --- channel confluences --- junction angle --- flow deflection zone --- flow retardation zone --- flow separation zone --- numerical modelling --- PANORMUS --- jets --- waves --- turbulence --- mixing --- diffusion --- advection --- river mouth --- flow mixing --- nonlinear shallow water equations --- macrovortices --- sub-grid turbulence --- seabed friction --- flow resistance --- roughness --- gravel-bed rivers --- casting technique --- CFD --- Kelvin–Helmholtz --- billow --- lobe --- cleft --- gravity current --- surface waves --- inclined negatively buoyant jets --- regular waves --- dilution --- sea discharges --- rivers --- maritime areas --- turbulent processes

Neuroproteomics

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ISBN: 9783039281060 9783039281077 Year: Pages: 318 DOI: 10.3390/books978-3-03928-107-7 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Neurology
Added to DOAB on : 2020-04-07 23:07:08
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The Neuroproteomics Special Issue overviews the unique challenges that must be addressed to carry out meaningful MS/proteomics analyses on neural tissues and the technologies that are available to meet these challenges. The articles on Alzheimer’s disease, addiction, and schizophrenia illustrate how MS/proteomics technologies can be used to improve our ability to diagnose and understand the molecular basis for neurological diseases. Several articles will be of interest to investigators beyond the field of neurological disorders. The review on the discovery of biofluid biomarkers of neurodegenerative dementias will be of interest to investigators searching for other disease biomarkers. Similarly, the review on the role of neuroproteomics in elucidating mechanisms of drug addiction provides an overview of the utility of MS/proteomics approaches for addressing critical questions in addiction neuroscience that should be applicable to investigators involved in virtually any area of biomedical research. Likewise, the article on developing targeted MS approaches for quantifying postsynaptic density proteins will be useful for any investigator who wishes to design targeted assays for virtually any protein. Finally, the peroxidase-mediated proximity labeling technology, described in the article on mapping the proteome of the synaptic cleft, will be of interest to investigators interested in mapping other spatially restricted proteomes.

Keywords

proteomics --- basal ganglia --- synapses --- synapse specificity --- neuronal circuits --- axons --- dendrites --- neurodegeneration --- synapse --- postsynaptic --- proteome --- mass spectrometry --- protein interaction networks --- connectome --- neurodegeneration --- Alzheimer’s disease --- cerebrospinal fluid --- plasma --- serum --- proteomics --- biomarkers --- LC-MS/MS --- cocaine --- addiction --- cytokine --- neuroimmune --- ventral tegmental area --- peptidylglycine ?-amidating monooxygenase --- cilia --- mating --- signal peptide --- prohormone convertase --- carboxypeptidase --- matrix metalloproteinase --- subtilisin --- pherophorin --- morphine --- opioid receptors --- conformational antibody --- analgesia --- GPCR signaling --- phosphorylation --- AMPA receptor complex --- transmembrane AMPA receptor regulatory protein --- synaptic plasticity --- adolescence --- corticosterone --- proteomics --- yohimbine --- progressive ratio --- reinstatement --- ethanol --- nicotinic receptor --- CaMKII --- PKA --- quantitative phosphoproteomics --- mouse --- phosphorylation --- nicotine --- proteomics --- proteome --- mass spectrometry --- Alzheimer’s disease --- protein aggregation --- laser capture microdissection --- splicing --- U1 snRNP --- synapse --- synaptic cleft --- trans-synaptic adhesion --- proximity labeling --- SynCAM --- Cadm --- Receptor-type tyrosine-protein phosphatase zeta --- R-PTP-zeta --- Ptprz1 --- neuroproteome --- drug abuse --- neuropeptidomics --- phosphorylation --- interactome --- cell type --- neuroscience --- proteomics --- mass spectrometry --- neuron --- proximity labeling --- affinity chromatography --- neuroproteomics --- biotinylation --- amphetamine --- spinophilin --- protein phosphatase-1 --- dopamine --- striatum --- mass spectroscopy --- bioinformatics --- FGF14 --- voltage gated channels --- schizophrenia --- autism --- Alzheimer’s Disease --- sex-specific differences --- synaptic plasticity --- cognitive impairment --- excitatory/inhibitory tone --- n/a --- postsynaptic density --- PSD --- parallel reaction monitoring --- PRM --- targeted proteomics --- data-independent acquisition --- DIA --- quantitative mass spectrometry --- n/a

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