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Mineral Surface Reactions at the Nanoscale

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ISBN: 9783038978961 9783038978978 Year: Pages: 220 DOI: 10.3390/books978-3-03897-897-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Geology --- Earth Sciences
Added to DOAB on : 2019-06-26 08:44:06
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Abstract

Reactions at mineral surfaces are central to all geochemical processes. As minerals comprise the rocks of the Earth, the processes occurring at the mineral–aqueous fluid interface control the evolution of the rocks and hence the structure of the crust of the Earth during processes such as metamorphism, metasomatism, and weathering. In recent years focus has been concentrated on mineral surface reactions made possible through the development of advanced analytical methods such as atomic force microscopy (AFM), advanced electron microscopies (SEM and TEM), phase shift interferometry, confocal Raman spectroscopy, and advanced synchrotron-based applications, to enable mineral surfaces to be imaged and analyzed at the nanoscale. Experiments are increasingly complemented by molecular simulations to confirm or predict the results of these studies. This has enabled new and exciting possibilities to elucidate the mechanisms that govern mineral–fluid reactions. In this Special Issue, “Mineral Surface Reactions at the Nanoscale”, we present 12 contributions that highlight the role and importance of mineral surfaces in varying fields of research.

Drug Metabolism, Pharmacokinetics and Bioanalysis

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ISBN: 9783038979166 9783038979173 Year: Pages: 230 DOI: 10.3390/books978-3-03897-917-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2019-06-26 08:44:06
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Drug metabolism/pharmacokinetics and drug interaction studies have been extensively carried out in order to secure the druggability and safety of new chemical entities throughout the development of new drugs. Recently, drug metabolism and transport by phase II drug metabolizing enzymes and drug transporters, respectively, as well as phase I drug metabolizing enzymes, have been studied. A combination of biochemical advances in the function and regulation of drug metabolizing enzymes and automated analytical technologies are revolutionizing drug metabolism research. There are also potential drug–drug interactions with co-administered drugs due to inhibition and/or induction of drug metabolic enzymes and drug transporters. In addition, drug interaction studies have been actively performed to develop substrate cocktails that do not interfere with each other and a simultaneous analytical method of substrate drugs and their metabolites using a tandem mass spectrometer. This Special Issue has the aim of highlighting current progress in drug metabolism/pharmacokinetics, drug interactions, and bioanalysis.

Keywords

procainamide --- N-acetylprocainamide --- ultra-high-pressure liquid chromatography --- rat --- plasma --- pharmacokinetics --- adalimumab --- immunoprecipitation --- liquid chromatography-quadrupole TOF MS --- bioanalysis --- GB3 --- Fabry disease --- LC-QTOF-MS/MS --- B6 --- 129-Glatm1Kul/J --- cytochrome P450 --- drug interaction --- liquid chromatography-tandem mass spectrometry --- organic anion transporting polypeptide --- pharmacokinetics --- Korean red ginseng extract --- metformin --- diabetes --- drug interaction --- pharmacokinetics --- efficacy --- ethyl glucuronide --- hair --- HPLC-MS/MS --- AUDIT score --- alcohol addiction --- eurycomanone --- Eurycoma longifolia --- bioavailability --- pharmacokinetic --- anthraquinone --- glycoside --- aglycone --- LC-MS/MS --- plasma --- protein precipitation --- loxoprofen --- CYP --- UGT --- human liver microsomes --- LC-HR/MS --- mematine --- drug interaction --- liquid chromatography-tandem mass spectrometry --- pharmacokinetics --- biopharmaceuticals --- drying technology --- protein stability --- bioavailability --- pharmacokinetics --- DA-9805 --- saikosaponin a --- paeonol --- imperatorin --- pharmacokinetics --- brain distribution --- Osthenol --- CYP --- UGT --- human liver microsomes --- glucuronidation --- Stauntonia hexaphylla leaf extract --- YRA-1909 --- pharmacokinetics --- chlorogenic acid --- neochlorogenic acid --- cryptochlorogenic acid --- caffeic acid --- caffeic acid O-glucuronides --- LC-MS/MS --- aceclofenac --- diclofenac --- esomeprazole --- pharmacokinetics --- gastric ulcer --- acetyl tributyl citrate --- pharmaceutical excipient --- pharmacokinetics --- metabolic stability --- plasma

Marine Chitin 2019

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ISBN: 9783039360727 / 9783039360734 Year: Pages: 288 DOI: 10.3390/books978-3-03936-073-4 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2020-06-09 16:38:57
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In 2019, we sent out a call for submissions to a Special Issue of Marine Drugs entitled “Marine Chitin 2019”, and we are pleased that this issue has now been published. Over 16 high-impact papers were included in this issue, which we now plan to publish as a book. In addition, we now seek to publish a further Special Issue of Marine Drugs, “Marine Chitin 2020–2021”. As before, we plan to produce an authoritative and exciting issue that will encompass breakthroughs in scientific and industrial chitin and chitosan research. Significant advances in chitin and chitosan research have been made since the 1970s, and current overviews in recent publications involving chitin and chitosan research advances are in need of an update.

Keywords

chitosan --- cytotoxicity --- polymer film --- sodium carbonate --- soluble chitosan complex --- chitin --- chitosan --- protease --- chitinase --- chitosan oligomers --- chitooligosaccharides --- anti-inflammatory action --- RAW264.7 macrophage --- chitosan oleate salt --- amphiphilic polymer --- PLGA --- nanoparticles --- mucoadhesion --- Caco-2 cell culture --- nile red --- curcumin --- chitooligosaccharide --- immunostimulatory activity --- RAW 264.7 cells --- mitogen-activated protein kinases (MAPK) --- phosphoinositide 3-kinases (PI3K)/Akt --- chitosan oligosaccharides --- streptomycin --- Pseudomonas aeruginosa --- biofilms --- conjugation --- chitin --- marine sponges --- scaffolds --- Aplysina archeri --- express method --- bromotyrosines --- crude oil --- blood --- methylene blue --- chitin --- chitosan --- Paenibacillus --- chitosanase --- chitosan oligomers --- ?-glucosidase inhibitor --- antioxidant --- Polybius henslowii --- marine resources --- chitosan --- chitooligosaccharides --- antifungal activity --- antioxidant activity --- chitin --- collagen --- electrospinning --- mechanical property --- 2D correlation spectroscopy --- polymorph --- chitosan lactate --- chitosan tartrate --- chitosan citrate --- Eudragit® S100 --- layer-by-layer film --- mucoadhesive film --- Tenofovir controlled release --- pH responsive release --- vaginal preexposure prophylaxis --- HIV sexual transmission --- chitin --- chitosan --- wound treatment --- derivatization --- nanocomposites --- chitosan --- antibacterial activity --- Clostridium perfringens --- pork sausage --- chitin --- chitosan --- chitooligosaccharides --- enzymatic modification --- biotechnology --- chitinase --- chitosanase --- lytic polysaccharide monooxygenase --- chitin deacetylase --- chitosan-coated liposomes --- chitosan hydrogel --- mucoadhesion --- vaginal infections --- antibacterial activity --- Staphylococcus epidermidis --- Staphylococcus aureus --- chitin --- roller compaction --- ball milling --- direct compression --- compression work --- crushing strength --- Hausner ratio --- Kawakita analysis --- bulk density --- dissolution

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english (2)

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2020 (1)

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