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Biological Crystallization

Authors: --- ---
ISBN: 9783039214037 9783039214044 Year: Pages: 184 DOI: 10.3390/books978-3-03921-404-4 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2019-12-09 11:49:15
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Abstract

For at least six hundred million years, life has been a fascinating laboratory of crystallization, referred to as biomineralization. During this huge lapse of time, many organisms from diverse phyla have developed the capability to precipitate various types of minerals, exploring distinctive pathways for building sophisticated structural architectures for different purposes. The Darwinian exploration was performed by trial and error, but the success in terms of complexity and efficiency is evident. Understanding the strategies that those organisms employ for regulating the nucleation, growth, and assembly of nanocrystals to build these sophisticated devices is an intellectual challenge and a source of inspiration in fields as diverse as materials science, nanotechnology, and biomedicine. However, “Biological Crystallization” is a broader topic that includes biomineralization, but also the laboratory crystallization of biological compounds such as macromolecules, carbohydrates, or lipids, and the synthesis and fabrication of biomimetic materials by different routes. This Special Issue collects 15 contributions ranging from biological and biomimetic crystallization of calcium carbonate, calcium phosphate, and silica-carbonate self-assembled materials to the crystallization of biological macromolecules. Special attention has been paid to the fundamental phenomena of crystallization (nucleation and growth), and the applications of the crystals in biomedicine, environment, and materials science.

Keywords

polymyxin resistance --- colistin resistance --- MCR-1 --- protein crystal nucleation --- thermodynamic and energetic approach --- protein ‘affinity’ to water --- solubility --- balance between crystal bond energy and destructive surface energies --- supersaturation dependence of the crystal nucleus size --- ependymin (EPN) --- ependymin-related protein (EPDR) --- mammalian ependymin-related protein (MERP) --- Campylobacter consisus --- Crohn’s disease --- circular dichroism --- protein crystallization --- Csep1p --- protein crystallization --- biochemical aspects of the protein crystal nucleation --- classical and two-step crystal nucleation mechanisms --- bond selection during protein crystallization --- equilibration between crystal bond and destructive energies --- protein crystal nucleation in pores --- crystallization in solution flow --- crystallization --- microseed matrix screening --- seeding --- optimization --- human carbonic anhydrase IX --- neutron protein crystallography --- microbially induced calcite precipitation (MICP) --- heavy metals --- wastewater treatment --- bioprecipitation --- calcium carbonate --- drug discovery --- education --- crystallization --- crystallography --- nucleation --- micro-crystals --- agarose --- ferritin --- lysozyme --- proteinase k --- insulin --- calcium carbonate --- {00.1} calcite --- lithium ions --- ultrasonic irradiation --- vaterite transformation --- adsorption --- calcein --- crystal violet --- dyes --- diffusion --- H3O+ --- reductants --- color change --- gradients --- biomorphs --- barium carbonate --- silica --- PCDA --- pyrrole --- droplet array --- crystal growth --- calcium carbonate --- high-throughput --- biomimetic crystallization --- biomineralization --- polyacrylic acid --- Cry protein crystals --- metallothioneins --- bioremediation --- heavy metal contamination --- nanoapatites --- graphene --- crystallization --- nanocomposites --- lysozyme --- L-tryptophan --- N-acetyl-D-glucosamine --- chitosan --- MTT assay --- GTL-16 cells --- Haloalkane dehalogenase --- halide-binding site --- random microseeding --- biomineralization --- biomimetic materials --- biomorphs --- calcium carbonate --- nanoapatites --- nucleation --- growth --- crystallization of macromolecules --- bioremediation --- materials science --- biomedicine

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