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Biosensors and Molecular Imprinting

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ISBN: 9783038425625 9783038425632 Year: Pages: VIII, 199 DOI: 10.3390/books978-3-03842-563-2 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology
Added to DOAB on : 2017-12-22 11:27:00
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Sensitive assays are often based on molecular recognition. Often stability problems have limited the use of such assays. The introduction of molecularly imprinted polymers (MIPs) eliminates such limitations. With the introduction of biosensors combined with MIPs, one gets a strong combination.This volume presents how MIPs are being produced, how MIPs are integrated in different sensor concepts and finally highlights some results in certain applications.

Label-Free Sensing

ISBN: 9783038422105 9783038422112 Year: Pages: 224 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Added to DOAB on : 2016-06-07 11:21:53
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Electrochemical Immunosensors and Aptasensors

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ISBN: 9783038424062 9783038424079 Year: Pages: VIII, 178 DOI: 10.3390/books978-3-03842-407-9 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General)
Added to DOAB on : 2017-06-02 09:40:26
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The possibility to integrate biorecognition elements into electrochemical detection systems has opened the way to a new class of powerful analytical devices named electrochemical (EC) biosensors. The first EC biosensors employed enzymes as recognition elements; however this limited their application to redox enzymes and natural or artificial redox substrates or inhibitors. Broadening this to include non-electroactive analytes was later possible thanks to the development of affinity sensors in which specific interactions between biomolecules are exploited for developing highly selective and sensitive biosensors. Presently, the combination of the exceptional molecular recognition capabilities of antibodies and aptamers with the sensitivity, low cost, practicality of use and handiness of electrochemical devices is leading to an impressive development of EC immunosensors and aptasensors that are potentially suitable to detect a wide range of analytes, following a path that is moving alongside the most recent advances in proteomics. Interestingly, with continued improvements and refinements in EC immunosensors based on the use of labels, together with intrinsically electroactive, or those with the ability to interact with electroactive molecules, a new generation of label-free sensors is being developed. This Special Issue takes stock of the state of the art and identifies prospects for EC immuno- and aptasensors, both labeled and label-free. Emphasis is placed on analytical applications for the rapid detection of disease markers and for toxicological and food analyses.

Magnetic Materials Based Biosensors

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ISBN: 9783038972549 9783038972556 Year: Pages: 212 DOI: 10.3390/books978-3-03897-255-6 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: General and Civil Engineering --- Internal medicine
Added to DOAB on : 2018-10-19 10:59:48
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ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms.[Selective and quantitative detection of different kinds of biocomponents plays an important role in biomedical applications, clinical diagnostics, environmental monitoring, toxicology, regenerative medicine and drug delivery. Therefore, multidisciplinary area of magnetic biosensing have been extensively developed in recent years, aiming to create compact analytical devices for non-expensive and low time consuming analysis provided at the point of care by non-skilled personnel. Biological samples exhibit very low magnetic background, and thus highly sensitive measurements of magnetic labels or magnetic nanoparticles enriched units can be performed without further processing. A magnetic biosensor is a compact analytical device in which magnetic transducer converts a magnetic field variation into a change of frequency, current, voltage, etc. Different types of magnetic effects are capable of creating magnetic biosensors with extra high sensitivity. This book describes interesting examples of magnetic materials based biosensors, including the synthesis of model materials for biosensor development, new engineering solutions and theoretical contributions on the magnetic biosensor sensitivity. Book contains 13 research works representing international multidisciplinary teams from Austria, China, Germany, Greece, Iran, Russia, Serbia, Spain, Taiwan and United States of America. It can be useful for PHD students and researches working in the field of magnetic nanomaterials and biomedical applications.

A Wearable Platform for Patient Monitoring during Mass Casualty Incidents

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ISBN: 9783731504863 Year: Pages: VII, 180 p. DOI: 10.5445/KSP/1000051989 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-28 18:37:01
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Based on physiological data, intelligent algorithms can assist with the classification and recognition of the most severely impaired victims. This book presents a new sensorbased triage platform with the main proposal to join different sensor and communications technologies into a portable device. This new device must be able to assist the rescue units along with the tactical planning of the operation. This work discusses the implementation and the evaluation of the platform.

State-Of-The- Art Sensors Technology in France 2016

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ISBN: 9783038426523 9783038426530 Year: Pages: 218 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Analytical Chemistry
Added to DOAB on : 2018-01-16 09:42:38
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This Special Issue aims to provide a comprehensive overview of state-of-the-art sensors technology in France. It includes research articles that consolidate our understanding of the state-of-the-art in this area and also four reviews on hot fields in sensor technology (nanomaterials, electronic tongue and optical fibre networks).

Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials

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ISBN: 9783039212590 9783039212606 Year: Pages: 186 DOI: 10.3390/books978-3-03921-260-6 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2019-12-09 11:49:15
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Nucleic acids (RNA and DNA) and their chemical analogs have been utilized as building materials due to their biocompatibility and programmability. RNA, which naturally possesses a wide range of different functions, is now being widely investigated for its role as a responsive biomaterial which dynamically reacts to changes in the surrounding environment. It is now evident that artificially designed self-assembling RNAs, that can form programmable nanoparticles and supra-assemblies, will play an increasingly important part in a diverse range of applications, such as macromolecular therapies, drug delivery systems, biosensing, tissue engineering, programmable scaffolds for material organization, logic gates, and soft actuators, to name but a few. The current exciting Special Issue comprises research highlights, short communications, research articles, and reviews that all bring together the leading scientists who are exploring a wide range of the fundamental properties of RNA and DNA nanoassemblies suitable for biomedical applications.

Biotechnological Applications of Phage and Phage-Derived Proteins

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ISBN: 9783039214419 9783039214426 Year: Pages: 236 DOI: 10.3390/books978-3-03921-442-6 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2019-12-09 11:49:15
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Phages have shown a high biotechnological potential with numerous applications. The advent of high-resolution microscopy techniques aligned with omic and molecular tools have revealed innovative phage features and enabled new processes that can be further exploited for biotechnological applications in a wide variety of fields. The high-quality original articles and reviews presented in this Special Issue demonstrate the incredible potential of phages and their derived proteins in a wide range of biotechnological applications for human benefit. Considering the emergence of amazing new available bioengineering tools and the high abundance of phages and the multitude of phage proteins yet to be discovered and studied, we believe that the upcoming years will present us with many more fascinating and new previously unimagined phage-based biotechnological applications.

Keywords

gene expression regulation --- molecular probe --- macromolecular interactions --- phage-host interaction --- bacteriophage --- endolysin --- Clostridium perfringens --- alpha-sheet --- cancerous tumors --- capsid dynamics --- drug delivery vehicles --- native gel electrophoresis --- neurodegenerative disease --- pathogenic viruses --- phage display --- landscape phage --- major coat protein --- nanomedicine --- diagnostics --- biosensors --- M13 bacteriophage --- biofilm --- porous structure --- filters --- self-assembly --- T7phage library --- sarcoidosis --- tuberculosis --- microarray --- immunoscreening --- R-type pyocin --- bacteriocin --- contractile injection systems --- Pseudomonas aeruginosa --- X-ray crystallography --- receptor-binding protein --- Shigella flexneri --- bacteriophage --- tailspike proteins --- O-antigen --- serotyping --- microtiter plate assay --- fluorescence sensor --- bacteriophages --- encapsulation --- niosomes --- transfersomes --- liposomes --- Staphylococcus aureus --- phage --- Enterococcus faecalis --- Streptococcus agalactiae --- culture enrichment --- bacteriophage --- diagnostics --- Listeria monocytogenes --- endolysin --- magnetic separation --- reporter phage --- endolysin --- Pal --- Cpl-1 --- safety --- toxicity --- immune response --- Streptococcus pneumoniae --- self-assembly --- nanotubular structures --- tail sheath protein --- bacteriophage vB_EcoM_FV3 --- Appelmans --- bacteriophage evolution --- bacteriophage recombination --- phage therapy --- Pseudomonas aeruginosa --- antibiotic resistance --- bacteriophages --- Myoviridae --- bacteriophage-derived lytic enzyme --- enzybiotics --- endolysin --- in vitro activity --- ESKAPE --- n/a

Advances in Prevention of Foodborne Pathogens of Public Health Concern during Manufacturing

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ISBN: 9783039219322 9783039219339 Year: Pages: 168 DOI: 10.3390/books978-3-03921-933-9 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2019-12-09 11:49:16
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According to a report from the U.S. Centers for Disease Control and Prevention (CDC), achieving safe and healthier foods was one of the top ten achievements of public health in the 20th century. However, considerable persisting challenges currently exist in developed nations and developing economies for further assuring the safety and security of the food supplies. According to CDC estimates, as many as 3000 American adults, as an example, and based on a recent epidemiological estimate of the World Health Organization, around 420,000 individuals around the globe, lose their lives annually due to foodborne diseases. This emphasizes the need for innovative and emerging interventions, for further prevention or mitigation of the risk of foodborne microbial pathogens during food processing and manufacturing. The current publication discusses recent advancements and progress in the elimination and decontamination of microbial pathogens during various stages of manufacturing and production. Special emphasis is placed on hurdle validation studies, investigating decontamination of non-typhoidal Salmonella enterica serovars, various serogroups of Shiga toxin-producing Escherichia coli, public health-significant serotypes of Listeria monocytogenes, and pathogenic species of Cronobacter.

Glassy Materials Based Microdevices

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ISBN: 9783038976189 Year: Pages: 284 DOI: 10.3390/books978-3-03897-619-6 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Electrical and Nuclear Engineering --- General and Civil Engineering --- Technology (General)
Added to DOAB on : 2019-03-21 15:50:41
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Microtechnology has changed our world since the last century, when silicon microelectronics revolutionized sensor, control and communication areas, with applications extending from domotics to automotive, and from security to biomedicine. The present century, however, is also seeing an accelerating pace of innovation in glassy materials; as an example, glass-ceramics, which successfully combine the properties of an amorphous matrix with those of micro- or nano-crystals, offer a very high flexibility of design to chemists, physicists and engineers, who can conceive and implement advanced microdevices. In a very similar way, the synthesis of glassy polymers in a very wide range of chemical structures offers unprecedented potential of applications. The contemporary availability of microfabrication technologies, such as direct laser writing or 3D printing, which add to the most common processes (deposition, lithography and etching), facilitates the development of novel or advanced microdevices based on glassy materials. Biochemical and biomedical sensors, especially with the lab-on-a-chip target, are one of the most evident proofs of the success of this material platform. Other applications have also emerged in environment, food, and chemical industries. The present Special Issue of Micromachines aims at reviewing the current state-of-the-art and presenting perspectives of further development. Contributions related to the technologies, glassy materials, design and fabrication processes, characterization, and, eventually, applications are welcome.

Keywords

micro-crack propagation --- severing force --- quartz glass --- micro-grinding --- microfluidics --- single-cell analysis --- polymeric microfluidic flow cytometry --- single-cell protein quantification --- glass molding process --- groove --- roughness --- filling ratio --- label-free sensor --- optofluidic microbubble resonator --- detection of small molecules --- chalcogenide glass --- infrared optics --- precision glass molding --- aspherical lens --- freeform optics --- micro/nano patterning --- 2D colloidal crystal --- soft colloidal lithography --- strain microsensor --- vectorial strain gauge --- compound glass --- microsphere --- resonator --- lasing --- sensing --- microresonator --- whispering gallery mode --- long period grating --- fiber coupling --- distributed sensing --- chemical/biological sensing --- direct metal forming --- glassy carbon micromold --- enhanced boiling heat transfer --- metallic microstructure --- microspheres --- microdevices --- glass --- polymers --- solar energy --- nuclear fusion --- thermal insulation --- sol-gel --- Ag nanoaggregates --- Yb3+ ions --- down-shifting --- photonic microdevices --- alkali cells --- MEMS vapor cells --- optical cells --- atomic spectroscopy --- microtechnology --- microfabrication --- MEMS --- microfluidic devices --- laser materials processing --- ultrafast laser micromachining --- ultrafast laser welding --- enclosed microstructures --- glass --- porous media --- fluid displacement --- spray pyrolysis technique --- dielectric materials --- luminescent materials --- photovoltaics --- frequency conversion --- device simulations --- europium --- luminescence --- hybrid materials --- microdevices --- light --- photon --- communications --- waveguides --- fibers --- biosensors --- microstructured optical fibers --- whispering gallery modes --- light localization --- optofluidics --- lab-on-a-chip --- femtosecond laser --- laser micromachining --- diffusion

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