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Barriers to Play and Recreation for Children and Young People with Disabilities. Exploring Environmental Factors

Authors: --- --- --- --- et al.
ISBN: 9783110526042 9783110526219 Year: Pages: 50 DOI: 10.1515/9783110526042 Language: English
Publisher: De Gruyter
Subject: Education --- Social Sciences
Added to DOAB on : 2017-08-25 16:10:55
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This report reviews international research into the barriers to play for children with disabilities. The authors come from different disciplinary backgrounds, in Sociology, Social Policy, Anthropology, Occupational Health and Education and bring different concerns to this review. They are united, however, in their adoption of a rights-based perspective. The UNCRC and UNCRPD emphasise the right to play for children with disabilities. Play is vital for child development. The problem of 'play deprivation' for many children with disabilities is very real. Yet the right to, and value of 'play for the sake of play', for fun and recreation, must not be forgotten in relation to the lives of children with disabilities. The focus in this report is upon barriers to play that exist beyond the minds and bodies of individual children, within a 'disabling' environment. Barriers include those associated with the design of the built environment, social attitudes and professional practices. The report maps an agenda for further research in this area, emphasising the need for participatory methodologies that capture the views and voices of children with disabilities, their friends and families, on this important issue of play.

Beyond the borders: The gates and fences of Neuroimmune interaction

Authors: --- ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889192748 Year: Pages: 119 DOI: 10.3389/978-2-88919-274-8 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Neurology
Added to DOAB on : 2015-12-03 13:02:24
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Neuroimmunology is a rapidly growing emerging field at which two old sciences have converged to integrate two different types of responses into a single coherent response involving the coordinated action of both systems, neural and immune. During long time it was thought that both systems worked separately and in divergent pathways. The brain was considered an immunoprivileged site and the immune organs were deemed as independent of any neural influence and also of nervous innervation. Time has gone and has proven that the borders between both systems were merely artificial. Since the beginning of Neuroimmunology in the 1980s much work has been done to elucidate the gates and fences in neuro-immune interactions. Brain was shown to be under the continuous surveillance of the immune system, even under basal physiological conditions in the absence of any pathology. Likely, it was found a profuse nervous innervation of lymphoid organs and even of single immune cells. Gates for direct neural immune communication were found both centrally and peripherally. Centrally, the gates, but also the fences, were situated at the brain barriers, the blood-brain barrier and the blood-cerebrospinal fluid barrier, and at the circunventricular organs. Peripherally, the fences constituted the apparent diverse nature of molecules involved in neural and immune signaling; however, time proved that both system were capable of producing the same signaling molecules and also systematically responded to the molecules released by the other system. Therefore, the gates were open for direct neural-immune communication at the peripheral level. This Research Topic aimed to include original reports, reviews and technical reports regarding the description of the gates and fences in neural immune interactions. We intended to provide an extensive view of the mechanisms governing central and peripheral neural-immune interactions, and the role of the borders, the blood-neural barriers, in the regulation of the neural-immune communication.

Institutional determinants of social inequality

Authors: ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889197859 Year: Pages: 124 DOI: 10.3389/978-2-88919-785-9 Language: English
Publisher: Frontiers Media SA
Subject: Psychology --- Science (General)
Added to DOAB on : 2017-02-03 17:04:57
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Understanding the factors that create and maintain social inequalities is a core question in social psychology. Research has so far mainly focused on the role of individual stereotyping, prejudice and discrimination. However, there is growing evidence that, beyond the “biased” acts of prejudiced individuals, structural factors related to the very functioning of institutions and organizations can play a role in the reproduction of social inequalities. Indeed, in industrialized countries, society is structured in a way that reflects the perspective of, is organized by, and benefits the dominant groups. In this Research Topic, we propose to bring together researchers who study how institutional ideologies and practices promote norms, rules and opportunities that favor dominant groups and disadvantage dominated groups. This question can be tackled by work investigating how institutional practices (e.g., grading, tracking, recruitment, …) and ideologies (e.g., meritocracy, individualism, protestant work ethic, …) shape the psychological experience of (dis)advantaged people. Moreover, another interesting venue is represented by work investigating how the institutional practices and ideologies are enacted by the agents (e.g., teachers, recruiters, leaders, …). Taking the perspective of agents allows to investigate how institutional functioning constrains the actual opportunities they provide to (dis)advantaged individuals. This could also highlight how institutional ideologies and practices are incorporated by agents, thus revealing mechanisms of change vs. perpetuation of the institutional functioning.

World of Walls: The Structure, Roles and Effectiveness of Separation Barriers 

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ISBN: 9781783743704 9781783743681 Year: Volume: 1 Pages: 152 DOI: http://doi.org/10.11647/OBP.0121 Language: English
Publisher: Open Book Publishers
Subject: Political Science --- History --- Migration
Added to DOAB on : 2017-10-10 12:00:18
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"We’re going to build a wall.”Borders have been drawn since the beginning of time, but in recent years artificial barriers have become increasingly significant to the political conversation across the world. Donald Trump was elected President of the United States while promising to build a wall on the Mexico border, and in Europe, the international movements of migrants and refugees have sparked fierce discussion about whether and how countries should restrict access to their territory by erecting physical barriers. Virtual walls are also built and crushed at increasing speed. In the post-9/11 era there is a greater danger from so-called "transnational non-state actors”, and computer hacking and cyberterrorism threaten to overwhelm our technological barriers.In this timely and original book, Said Saddiki scrutinises the physical and virtual walls located in four continents, including Israel, India, the southern EU border, Morocco, and the proposed border wall between Mexico and the US. Saddiki’s detailed analysis explores the tensions between the rise of globalisation, which some have argued will lead to a "borderless world” and "the end of the nation-state”, and the rapid development in recent decades of border control systems.Saddiki examines both regular and irregular cross-border activities, including the flow of people, goods, ideas, drugs, weapons, capital, and information, and explores the disparities that are reflected by barriers to such activities. He considers the consequences of the construction of physical and virtual walls, including their impact on international relations and the rise of the multi-billion dollar security market.World of Walls: The Structure, Roles and Effectiveness of Separation Barriers is important reading for all those interested in the topics of immigration, border security, international relations, and policy.

Continuous Quality Improvement - Advancing Understanding of Design, Application, Impact and Evaluation of CQI Approaches

Authors: --- ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889453771 Year: Pages: 100 DOI: 10.3389/978-2-88945-377-1 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Botany
Added to DOAB on : 2018-11-16 17:17:57
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Continuous Quality Improvement (CQI) methods are increasingly widely used to bridge the gaps between the evidence base for best clinical practice, what actually happens in practice, and the achievement of better population health outcomes. Among a range of quality improvement strategies, CQI methods are characterised by iterative and ongoing use of specific processes to identify quality problems, develop solutions, and implement and evaluate changes. The application of CQI processes in health is evolving and evidence of their success continues to emerge. There is, however, a need to enhance understanding of how best to implement, scale-up and evaluate CQI programs for the purpose of improving quality of care and population health outcomes in different contexts. This research topic aims to attract articles that add to knowledge of useful approaches to tailoring CQI methods for different contexts or purposes, and for implementation, scale-up and evaluation of CQI interventions/programs.

Bridging the Gap Between Policy and Science in Assessing the Health Status of Marine Ecosystems, 2nd Edition

Authors: --- --- --- --- et al.
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889451265 Year: Pages: 546 DOI: 10.3389/978-2-88945-126-5 Language: English
Publisher: Frontiers Media SA
Subject: Oceanography --- Science (General)
Added to DOAB on : 2017-07-06 13:27:36
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Marine management requires approaches which bring together the best research from the natural and social sciences. It requires stakeholders to be well-informed by science and to work across administrative and geographical boundaries, a feature especially important in the inter-connected marine environment. Marine management must ensure that the natural structure and functioning of ecosystems is maintained to provide ecosystem services. Once those marine ecosystem services have been created, they deliver societal goods as long as society inputs its skills, time, money and energy to gather those benefits. However, if societal goods and benefits are to be limitless, society requires appropriate administrative, legal and management mechanisms to ensure that the use of such benefits do not impact on environmental quality, but instead support its sustainable use.

Social Safety and Security

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ISBN: 9783039281466 / 9783039281473 Year: Pages: 112 DOI: 10.3390/books978-3-03928-147-3 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Law
Added to DOAB on : 2020-01-30 16:39:46
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Social safety in social environments entails the sense of feeling safe with other people. Thus, social safety and security are very important to our life. Although research in this area has made significant progress in the past few years, there are still many social problems that require attention and further development in order to secure peace of mind. There is a very clear and accurate understanding and judgment of the overall situation of social security in the current and future period. This Special Issue focuses on a number of contemporary issues in social safety and security. The objective of this book is to rapidly disseminate the latest research and knowledge in this important area.

Health Benefits of Mediterranean Diet

Authors: ---
ISBN: 9783039214938 / 9783039214945 Year: Pages: 274 DOI: 10.3390/books978-3-03921-494-5 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Social Sciences --- Sociology
Added to DOAB on : 2019-12-09 11:49:15
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Growing evidence shows that a dietary pattern inspired by Mediterranean dietprinciples is associated with numerous health benefits. A Mediterranean-typediet has been demonstrated to exert a preventive effect toward cardiovasculardiseases, in both Mediterranean and non-Mediterranean populations. Part ofthese properties may depend on a positive action toward healthier metabolism,decreasing the risk of diabetes and metabolic-syndrome-related conditions.Some studies also suggested a potential role in preventing certain cancers. Finally,newer research has showed that a higher adherence to the Mediterranean diet isassociated with a lower risk of cognitive decline, depression, and other mentaldisorders. Overall, a better understanding of the key elements of this dietarypattern, the underlying mechanisms, and targets, are needed to corroboratecurrent evidence and provide insights on new and potential outcomes.ThisSpecial Issue welcomes original research and reviews of literature concerningthe Mediterranean diet and various health outcomes:Observational studies onestablished nutritional cohorts (preferred), case-control studies, or populationsample on the association with non-communicable diseases;Level of evidenceon the association with human health, including systematic reviews and metaanalyses;Evaluation of application of Mediterranean diet principles in non-Mediterranean countries;Description of mechanisms of action, pathways, andtargets at the molecular level, including interaction with gut microbiota.

Keywords

Mediterranean diet --- dietary intervention --- diet --- nutrition --- translation --- non-alcoholic fatty liver disease --- cardiovascular disease --- Mediterranean diet --- physical activity --- self-concept --- socioeconomic factors --- Mediterranean diet --- diabetes --- cardiovascular risk --- glucose control --- plasma lipids --- relative Mediterranean diet score --- Mediterranean diet --- questionnaire --- children --- adolescents --- obesity --- Mediterranean diet --- athletes --- Spain --- dietary intake --- catechins --- resveratrol --- olive oil --- wine --- BMI --- Mediterranean diet --- barriers --- dietary change --- childbearing age --- diet quality --- depressive symptoms --- risk factors --- epidemiology --- immune system --- prevention --- hypothalamic–pituitary–adrenal-HPA axis --- Mediterranean diet --- motivational climate --- sports --- university students --- Mediterranean diet --- metabolomics --- microbiome --- Mediterranean diet --- DNA damage --- DNA repair --- telomere length --- dietary intervention study --- Mediterranean diet --- sleep quality --- cognitive decline --- dementia --- weight status --- mental health --- obesity --- cohort --- Italy --- Mediterranean diet --- quality of life --- mental health --- fruit --- vegetable --- dairy --- nuts --- fish --- whole-grain --- food groups --- Mediterranean diet --- pregnancy --- offspring --- child health --- Mediterranean diet --- Mediterranean diet pyramid --- noncommunicable diseases --- Mediterranean Diet --- public health policy --- childhood obesity --- healthy lifestyle --- health communication --- n/a

Drug Delivery Technology Development in Canada

Authors: ---
ISBN: 9783039280049 / 9783039280056 Year: Pages: 352 DOI: 10.3390/books978-3-03928-005-6 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2020-01-07 09:21:22
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Canada continues to have a rich history of ground-breaking research in drug delivery within academic institutions, pharmaceutical industry and the biotechnology community.

Keywords

doxorubicin --- MG63 --- Vitamin D --- DOX-Vit D --- hypoxia-induced chemoresistance --- cisplatin --- polymeric micelle --- EGFR-targeted therapy --- STAT3 --- HIF-1 --- GE11 peptide --- pharmacological Inhibitors of HIF-1 and STAT3 --- combination therapy --- pharmacokinetics --- antibodies --- radiolabeling --- biodistribution --- mouse models --- oral formulation --- amphotericin B --- fungal infections --- parasitic infections --- developing world --- drug delivery --- liposomes --- drug delivery systems --- innovation --- lipid nanoparticles --- Metaplex --- triggered drug release --- liposomes --- ultrasound --- magnetic fields --- radiation --- oral delivery --- biological barriers --- co-delivery --- throughput --- sustained delivery --- phospholipid complex --- rosmarinic acid --- bioaccessibility --- dissolution --- TNO gastrointestinal model --- gastrointestinal simulator --- phytosterols --- tocopherols --- liposomes --- canola oil deodorizer distillate --- model orange juice --- virus --- plant --- bacteriophage --- phage display --- drug discovery --- encapsulation --- drug delivery --- blood-brain barrier --- intra-arterial chemotherapy --- malignant gliomas --- primary central nervous system lymphomas --- transdermal drug delivery --- Canada --- skin --- permeation enhancers --- oral, head and neck squamous cell carcinoma --- targeted therapies --- drug delivery systems --- nanoparticles --- controlled drug delivery --- circadian clock --- chronotherapy --- precision medicine --- cationic gemini surfactant --- melphalan --- inclusion complex --- ROESY NMR spectroscopy --- 3D spheroid --- drug-resistant melanoma --- liposome --- water miscible solvents --- remote loading --- staurosporine --- cancer --- gambogic acid --- loading gradients --- mefloquine --- child friendly formulation --- blood-brain barrier (BBB) --- drug delivery --- transient modulation --- HAV6 cadherin peptide --- adenanthin --- magnetic resonance imaging (MRI) --- medulloblastoma --- drug delivery --- pharmaceutics --- drug development --- formulation and dosage form development --- translational research --- biologicals --- small molecules --- clinical trials --- pharmacokinetics --- medical devices --- route of administration --- nifedipine --- emulsion --- flavonoids --- topical formulation --- quercetin --- photostabilizers

Breastfeeding and Human Lactation

Authors: ---
ISBN: 9783038979302 / 9783038979319 Year: Pages: 450 DOI: 10.3390/books978-3-03897-931-9 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Nutrition and Food Sciences
Added to DOAB on : 2019-06-26 08:44:06
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Human lactation has evolved to produce a milk composition that is uniquely-designed for the human infant. Not only does human milk optimize infant growth and development, it also provides protection from infection and disease. More recently, the importance of human milk and breastfeeding in the programming of infant health has risen to the fore. Anchoring of infant feeding in the developmental origins of health and disease has led to a resurgence of research focused in this area. Milk composition is highly variable both between and within mothers. Indeed the distinct maternal human milk signature, including its own microbiome, is influenced by environmental factors, such as diet, health, body composition and geographic residence. An understanding of these changes will lead to unravelling the adaptation of milk to the environment and its impact on the infant. In terms of the promotion of breastfeeding, health economics and epidemiology is instrumental in shaping public health policy and identifying barriers to breastfeeding. Further, basic research is imperative in order to design evidence-based interventions to improve both breastfeeding duration and women’s breastfeeding experience.

Keywords

human milk --- breastfed infants --- body composition --- anthropometrics --- milk intake --- bioelectrical impedance spectroscopy --- ultrasound skinfolds --- maternal factors --- infant --- feeding --- preterm --- premature --- bottle --- human milk --- breastfeeding --- nipple shield --- infant feeding --- choline --- phosphocholine --- glycerophosphocholine --- lactation --- human milk --- infants --- adequate intake --- dietary recommendations --- Canada --- Cambodia --- breast milk --- galactogogues --- mothers of preterm infants --- breastfeeding --- attitudes --- knowledge --- midwifery --- formula supplementation --- justification of supplementation --- maternal wellbeing --- maternal distress --- post-partum distress --- breastfeeding support --- paternal role --- partner support --- infant --- Ireland --- passive immunity --- antibodies --- lactation --- peptidomics --- prematurity --- proteolysis --- breast milk --- preterm infant --- enteral nutrition --- lipids --- omega-3 fatty acids --- omega-6 fatty acids --- Docosahexaenoic acid --- Arachidonic acid --- long-chain polyunsaturated fatty acids --- pregnancy --- breast milk --- lactation --- maternal diet --- n-6 and n-3 polyunsaturated fatty acid --- docosahexaenoic acid --- zinc deficiency --- plasma zinc --- lactating women --- zinc supplementation --- Quito --- Ecuador --- Andean region --- GDM --- lactation --- thyroid --- triiodothyronine --- thyroxine --- thyroid antibodies --- breastfeeding --- knowledge --- practice --- barriers --- social support --- professional support --- raw breast milk --- cytomegalovirus --- milk-acquired infections --- preterm infant --- adipokines --- adiponectin --- leptin --- breastfeeding --- infant --- body composition --- bioelectrical impedance spectroscopy --- ultrasound skinfolds --- human milk --- lactation --- human lactation --- expressing --- milk synthesis --- fat synthesis --- human milk --- milk metabolites --- lactation --- milk metabolomics --- human milk --- breastfeeding --- lactation --- lipids --- lipidomics --- mass spectrometry --- chromatography --- NMR spectroscopy --- human milk --- sex-specificity --- infant growth --- early life nutrition --- postnatal outcomes --- breastfeeding --- breast milk --- human milk --- colostrum --- IgA --- HGF --- TGF-? --- growth factors --- geographical location --- human milk --- potassium --- sodium --- ICP-OES --- ion selective electrode --- lactoferrin --- human milk --- infection --- immunity --- antisecretory factor --- human milk --- breast milk --- breastfeeding --- inflammation --- lactoferrin --- candida --- human milk --- milk cells --- immune cells --- antimicrobial proteins --- human milk --- breastfeeding --- ethnicity --- composition --- diet --- responsive feeding --- breastfeeding --- breastmilk --- babywearing --- co-sleeping --- mother–infant interaction --- feeding cues --- maternal responsiveness --- mother–infant physical contact --- proximal care --- fatty acids --- long-chain polyunsaturated fatty acids --- endocannabinoids --- infant health --- breast milk --- casein --- whey --- protein --- breastfeeding --- infant --- body composition --- bioelectrical impedance spectroscopy --- ultrasound skinfolds --- human milk --- calculated daily intakes --- lactation --- human milk --- metabolites --- microbiome --- mode of delivery --- caesarean section --- proton nuclear magnetic resonance --- breastfeeding --- human milk composition --- body composition --- maternal diet --- infant growth --- appetite regulation --- N-acylethanolamines --- OEA --- SEA --- PEA --- breastfeeding --- human milk composition --- obesity --- Breastfeeding --- human lactation --- lactation --- human milk --- breast milk --- milk composition

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