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Leeuwenhoek's Legatees and Beijerinck's Beneficiaries

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ISBN: 9789048544066 9789463720113 Year: Pages: 361 DOI: 10.5117/9789463720113 Language: English
Publisher: Amsterdam University Press
Subject: Medicine (General) --- History
Added to DOAB on : 2020-02-05 11:21:20
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Abstract

The title of the book pays tribute to two Dutch scientists without whom virology would arguably not exist today, at least not in its present guise. The first is Antony van Leeuwenhoek, whose reports of microscopic discoveries in the early eighteenth century aroused interest in the world of invisible creatures. His findings laid the basis for a theory of a particulate cause of infectious diseases, but, as George Rosen wrote, without any tangible results in support of the theory (1993/1958, pp. 84-85). Some 250 years later Martinus Willem Beijerinck launched the discipline of virology with his idea that tobacco mosaic disease (TMD) was caused by a living contagious fluid or filterable living pathogen.

Keywords

History --- medicine --- microbiology --- virology

Current Topics in Zika

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ISBN: 9781789232707 9781789232714 Year: Pages: 98 DOI: 10.5772/65145 Language: English
Publisher: IntechOpen
Subject: Animal Sciences --- Microbiology
Added to DOAB on : 2019-10-03 07:51:51

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Zika was an arbovirus not considered relevant until the epidemics of 2007, where in the islands of the Pacific, Yap, Micronesia, and others, and later in the Americas in 2015-2016, it created a significant public health threat. Zika is a flavivirus that has been especially important not just for the high number of cases but also for its related morbidity. In the case of adult population, multiple neurological diseases are already associated and in pregnant women because of its confirmed teratogenic capacity, leading to microcephaly as well as other central nervous system (CNS) birth defects. This book tried to update the significant epidemiological and clinical research in many aspects with a multinational perspective.

Influenza - Therapeutics and Challenges

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Book Series: Infectious Diseases ISSN: 26316188 ISBN: 9781789237146 9781789237153 Year: Volume: 1 Pages: 160 DOI: 10.5772/intechopen.71939 Language: English
Publisher: IntechOpen
Subject: Animal Sciences --- Microbiology
Added to DOAB on : 2019-10-03 07:51:52

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This book gives a comprehensive overview of recent advances in influenza, as well as general concepts of molecular biology of influenza infections, epidemiology, immunopathology, prevention, and current clinical recommendations in management of influenza, including preparation of vaccines, assessment of the safety and quality of influenza vaccines and adjuvants highlighting the ongoing issues and recent advances, with future directions in prevention and therapeutic strategies. I hope that this work might increase the interest in this field of research and that the readers will find it useful for their investigations, management, and clinical usage.

Advances in Ebola Control

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ISBN: 9781789230703 9781789230710 Year: Pages: 98 DOI: 10.5772/intechopen.69364 Language: English
Publisher: IntechOpen
Subject: Animal Sciences --- Microbiology
Added to DOAB on : 2019-10-03 09:47:13

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Ebola epidemics have had immediate and lasting impact in Africa and beyond, with its high case fatality and societal disruption. Its rapid spread, coupled with the limited knowledge, serves as a recipe for disaster and panic in the community. Health workers are particularly at risk, paying heavily with their lives. Sharing knowledge from various experts in basic sciences that support vaccine and drug development, as well as improving community surveillance and case management, enriches our understanding of this highly fatal and contagious disease. In a world that is fast becoming a global village, communicable diseases from low-resource setting are gradually becoming a global health threat. This book seeks to discuss emerging advances in the Ebola control.

Ranaviruses: Lethal Pathogens of Ectothermic Vertebrates

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ISBN: 9783319137544 9783319137551 Year: Pages: 246 DOI: 10.1007/978-3-319-13755-1 Language: English
Publisher: Springer Nature
Subject: Therapeutics --- Biotechnology --- Microbiology
Added to DOAB on : 2016-04-12 15:59:14
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This is the first book on ranaviruses. Ranaviruses are double-stranded DNA viruses that cause hemorrhagic disease in amphibians, reptiles, and fish. They have caused mass die-offs of ectothermic vertebrates in wild and captive populations around the globe. There is evidence that this pathogen is emerging and responsible for population declines in certain locations. Considering that amphibians and freshwater turtles are suitable hosts and the most imperiled vertebrate taxa in the world, ranaviruses can have significant impacts on biodiversity and ecosystem function. Additionally, many fish that are raised in aquaculture facilities and traded internationally are suitable hosts; thus, the potential economic impact of ranaviruses is significant. Ranaviruses also serve as a model for replication and gene function of large double-stranded DNA viruses. There is an urgent need to assemble the contemporary information on ranaviruses and provide guidance on how to assess their threats in populations. Through the Global Ranavirus Consortium, 24 experts from six countries were organize to write this volume, the first book on ranaviruses. The book begins with a discussion on the global extent of ranaviruses, case histories of infection and disease in ectothermic vertebrates, and current phylogeny. Basic principles of ranavirus ecology and evolution are covered next, with a focus on host-pathogen interactions and how the virus emerges in its environment. There are two chapters that will discuss the molecular biology of ranaviruses, host response to infection, and the genes responsible for immune system evasion. One chapter establishes standards for testing for infection and diagnosing ranaviral disease. The book ends by providing guidance on how to design ranavirus surveillance studies and analyze data to determine risk, and discussing the role of the Global Ranavirus Consortium in organizing research and outreach activities.

Virus Bioinformatics

Authors: --- --- ---
ISBN: 9783039218820 9783039218837 Year: Pages: 330 DOI: 10.3390/books978-3-03921-883-7 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2020-04-07 23:07:08
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Virus bioinformatics is evolving and succeeding as an area of research in its own right, representing the interface of virology and computer science. Bioinformatic approaches to investigate viral infections and outbreaks have become central to virology research, and have been successfully used to detect, control, and treat infections of humans and animals. As part of the Third Annual Meeting of the European Virus Bioinformatics Center (EVBC), we have published this Special Issue on Virus Bioinformatics.

Keywords

bioinformatics --- virus --- comparative genomics --- software --- Base-By-Base --- BBB --- poxvirus --- ASFV --- MSA --- foot-and-mouth disease virus (FMDV) --- bovine soft palate --- nasopharynx --- transcriptomics --- proteomics --- bioinformatics --- virus-host interaction --- innate immune system --- interferon-stimulated genes (ISG) --- cellular immunity --- codon frequency distribution --- HPV58 --- minor capsid protein --- TLR agonist --- prophylaxis --- virus --- infection --- fluorescent reporter protein --- image quantification --- Hepatitis C virus --- Yellow Fever Virus --- polyomavirus --- Coxsackievirus B4 --- bivalve --- virome --- RNA-seq --- RNA viruses --- sncRNA --- ADAR --- RNAi --- Marek’s disease virus (MDV) --- RNA-seq --- transcriptome --- splicing --- polycistronic viral transcripts --- primary B cells --- RB1B --- CVI988/Rispens --- ICP0 --- DNA replication --- ori --- mitochondria --- Rickettsia --- gram-positive bacteria --- APMV --- Mimivirus --- giant virus --- eukaryogenesis --- flavivirus --- non-coding RNA --- secondary structure --- endogenous viral elements --- bioinformatics --- horizontal gene transfer --- virus-to-host gene transfer --- HMM --- tobacco mosaic virus --- Drosophila --- capsid protein --- deep sequencing --- virus genomics --- hepatitis C virus --- variant calling --- sequence interpretation --- drug resistance --- bioinformatics --- alignment --- assembly --- taxonomic classification --- time series --- data transformation --- DWT --- DFT --- PAA --- data compression --- compressive genomics --- RNAseq --- honey bees --- deformed wing virus --- quasispecies --- apiary pests --- recombination --- mRNA structure --- structure database --- secondary structure --- viral mRNA --- subVOG --- structurally related --- RNA structure --- structurally homogenous --- structurally related --- mRNA families --- Amebae viruses --- viral evolution --- protein domains --- mimivirus --- dsdna viruses --- translation machinery --- pandoravirus --- NCLDV --- virology --- virus bioinformatics --- software --- systems virology --- metagenomics --- virome --- viral taxonomy --- virus classification --- genome evolution --- bacteriophage --- virosphere --- chemical organization theory --- influenza A --- virus dynamics modeling --- complex networks analysis --- viral metagenome --- groundwater --- aquifer --- AquaDiva --- sequencing library preparation --- virus proteomics --- mass spectrometry --- virus diagnostics --- data analysis --- targeted proteomics --- peptide selection --- parallel reaction monitoring

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