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Investigation of coherent microscopic defects inside the tunneling barrier of a Josephson junction

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Book Series: Experimental Condensed Matter Physics / Karlsruher Institut für Technologie, Physikalisches Institut ISSN: 21919925 ISBN: 9783731502104 Year: Volume: 11 Pages: 111 p. DOI: 10.5445/KSP/1000040666 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Physics (General)
Added to DOAB on : 2019-07-30 20:01:58
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In disordered solids, two-level atomic-tunneling systems are present in large quantity. Only recently, superconducting qubits opened a door for a detection and individual coherent manipulation of such microscopic quantum systems. We succeeded to tune the resonance frequencies of these systems by applying external strain on the qubit chip. Moreover, we observed and analyzed the interaction between two coupled tunneling systems.

Applications of Photogrammetry for Environmental Research

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ISBN: 9783039281800 9783039281817 Year: Pages: 154 DOI: 10.3390/books978-3-03928-181-7 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General)
Added to DOAB on : 2020-01-30 16:39:46
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The book presents a collection of papers focused on recent progress in key areas of photogrammetry for environmental research. Applications oriented to the understanding of natural phenomena and quantitative processes using dataset from photogrammetry (from satellite to unmanned aerial vehicle images) and terrestrial laser scanning, also by a diachronic approach, are reported. The book covers topics of interest of many disciplines from geography, geomorphology, engineering geology, geotechnology, including landscape description and coastal studies. Mains issues faced by the book are related to applications on coastal monitoring, using multitemporal aerial images, and investigations on geomorphological hazard by the joint use of proximal photogrammetry, terrestrial and aerial laser scanning aimed to the reconstruction of detailed surface topography and successive 2D/3D numerical simulations for rock slope stability analyses. Results reported in the book bring into evidence the fundamental role of multitemporal surveys and reliable reconstruction of morphologies from photogrammetry and laser scanning as support to environmental researches.

DNA Replication Stress

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ISBN: 9783039213894 9783039213900 Year: Pages: 368 DOI: 10.3390/books978-3-03921-390-0 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2019-12-09 16:10:12
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This Special Issue of International Journal of Molecular Sciences (IJMS) is dedicated to the mechanisms mediated at the molecular and cellular levels in response to adverse genomic perturbations and DNA replication stress. The relevant proteins and processes play paramount roles in nucleic acid transactions to maintain genomic stability and cellular homeostasis. A total of 18 articles are presented which encompass a broad range of highly relevant topics in genome biology. These include replication fork dynamics, DNA repair processes, DNA damage signaling and cell cycle control, cancer biology, epigenetics, cellular senescence, neurodegeneration, and aging. As Guest Editor for this IJMS Special Issue, I am very pleased to offer this collection of riveting articles centered on the theme of DNA replication stress. The blend of articles builds upon a theme that DNA damage has profound consequences for genomic stability and cellular homeostasis that affect tissue function, disease, cancer, and aging at multiple levels and through unique mechanisms. I thank the authors for their excellent contributions, which provide new insight into this fascinating and highly relevant area of genome biology.

Keywords

barley --- chromosome --- DNA replication pattern --- EdU --- mutagens --- DNA replication --- DNA damage --- DNA repair --- genome integrity --- A549 cells --- H1299 cells --- heterogeneity --- DNA damage response --- 8-chloro-adenosine --- DNA replication --- S phase --- origin firing --- TopBP1 --- ATR --- DNA fiber assay --- APE2 --- ATR-Chk1 DDR pathway --- Genome integrity --- SSB end resection --- SSB repair --- SSB signaling --- DNA replication stress --- genome stability --- ubiquitin --- replication fork restart --- translesion synthesis --- template-switching --- homologous recombination --- Fanconi Anemia --- G protein-coupled receptor (GPCR) --- aging --- DNA damage --- ?-arrestin --- G protein-coupled receptor kinase (GRK) --- interactome --- G protein-coupled receptor kinase interacting protein 2 (GIT2) --- ataxia telangiectasia mutated (ATM) --- clock proteins --- energy metabolism --- neurodegeneration --- cellular senescence --- ageing --- Alzheimer’s disease --- multiple sclerosis --- Parkinson’s disease --- lipofuscin --- SenTraGorTM (GL13) --- senolytics --- DNA replication --- DNA repair --- DNA damage response --- DNA translocation --- DNA helicase --- superfamily 2 ATPase --- replication restart --- fork reversal --- fork regression --- chromatin remodeler --- C9orf72 --- ALS --- motor neuron disease --- R loops, nucleolar stress --- neurodegeneration --- Difficult-to-Replicate Sequences --- replication stress --- non-B DNA --- Polymerase eta --- Polymerase kappa --- genome instability --- common fragile sites --- Microsatellites --- cancer --- DNA double-strand repair --- premature aging --- post-translational modification --- protein stability --- replication stress --- Werner Syndrome --- Werner Syndrome Protein --- dormant origins --- replicative stress --- replication timing --- DNA damage --- genome instability --- cancer --- Thermococcus eurythermalis --- endonuclease IV --- AP site analogue --- spacer --- DNA repair --- DNA repair --- double strand break repair --- exonuclease 1 --- EXO1 --- mismatch repair --- MMR --- NER --- nucleotide excision repair --- strand displacements --- TLS --- translesion DNA synthesis --- POL? --- mutation frequency --- mutations spectra --- SupF --- mutagenicity --- oxidative stress --- DNA damage --- DNA repair --- replication --- 8-oxoG --- epigenetic --- gene expression --- helicase --- cell cycle checkpoints --- genomic instability --- G2-arrest --- cell death --- repair of DNA damage --- adaptation --- n/a

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