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Advances in Systems Immunology and Cancer

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889193134 Year: Pages: 108 DOI: 10.3389/978-2-88919-313-4 Language: English
Publisher: Frontiers Media SA
Subject: Genetics --- Biology --- Biotechnology --- General and Civil Engineering --- Psychiatry --- Medicine (General) --- Physiology --- Neurology --- Science (General)
Added to DOAB on : 2016-02-05 17:24:33
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Aims and Scope: The Research Topic is designed to feature the latest innovative and leading-edge research, reviews and opinions on the study of complex and dynamic processes related to the mammalian immune system and cancer. All papers were meticulously selected to present our readers the multidisciplinary approach to tackle the existing challenges faced in these important fields. From high throughput experimental methodologies to computational and theoretical approaches, the articles are intended to introduce physicists, chemists, computer scientists, biologists and immunologists the idea of systems biology approach to the understanding of mammalian immune system and cancer processes. Attention was given to works that developed more effective approaches to the treatment of proinflammatory disease and cancer. The strong interdisciplinary focus will discuss biological systems at the level from a few molecules to the entire organism. Specific focus domain includes: Innate and adaptive immunity, cancer and cancer stem cell, genomic, proteomic and metabolic analysis, imaging, biophysics of immune and cancer response, computational modeling, non-linear analysis, statistical analysis, translational and disease models Types of articles: Viewpoint, commentaries, research letters, research articles, review and methodologies

Nonparametric identification of nonlinear dynamic systems

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Book Series: Schriftenreihe des Instituts für Technische Mechanik, Karlsruher Institut für Technologie ISSN: 16143914 ISBN: 9783731508342 Year: Volume: 32 Pages: XXVIII, 194 p. DOI: 10.5445/KSP/1000085419 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-28 18:37:01
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A nonparametric identification method for highly nonlinear systems is presented that is able to reconstruct the underlying nonlinearities without a priori knowledge of the describing nonlinear functions. The approach is based on nonlinear Kalman Filter algorithms using the well-known state augmentation technique that turns the filter into a dual state and parameter estimator, of which an extension towards nonparametric identification is proposed in the present work.

Nonparametric Econometric Methods and Application

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ISBN: 9783038979647 / 9783038979654 Year: Pages: 224 DOI: 10.3390/books978-3-03897-965-4 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Mathematics
Added to DOAB on : 2019-06-26 08:44:06
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The present Special Issue collects a number of new contributions both at the theoretical level and in terms of applications in the areas of nonparametric and semiparametric econometric methods. In particular, this collection of papers that cover areas such as developments in local smoothing techniques, splines, series estimators, and wavelets will add to the existing rich literature on these subjects and enhance our ability to use data to test economic hypotheses in a variety of fields, such as financial economics, microeconomics, macroeconomics, labor economics, and economic growth, to name a few.

New Developments in Statistical Information Theory Based on Entropy and Divergence Measures

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ISBN: 9783038979364 / 9783038979371 Year: Pages: 344 DOI: 10.3390/books978-3-03897-937-1 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Social Sciences --- Sociology --- Statistics
Added to DOAB on : 2019-06-26 08:44:06
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This book presents new and original research in Statistical Information Theory, based on minimum divergence estimators and test statistics, from a theoretical and applied point of view, for different statistical problems with special emphasis on efficiency and robustness. Divergence statistics, based on maximum likelihood estimators, as well as Wald’s statistics, likelihood ratio statistics and Rao’s score statistics, share several optimum asymptotic properties, but are highly non-robust in cases of model misspecification under the presence of outlying observations. It is well-known that a small deviation from the underlying assumptions on the model can have drastic effect on the performance of these classical tests. Specifically, this book presents a robust version of the classical Wald statistical test, for testing simple and composite null hypotheses for general parametric models, based on minimum divergence estimators.

Keywords

sparse --- robust --- divergence --- MM algorithm --- Bregman divergence --- generalized linear model --- local-polynomial regression --- model check --- nonparametric test --- quasi-likelihood --- semiparametric model --- Wald statistic --- composite likelihood --- maximum composite likelihood estimator --- Wald test statistic --- composite minimum density power divergence estimator --- Wald-type test statistics --- Bregman divergence --- general linear model --- hypothesis testing --- influence function --- robust --- Wald-type test --- log-linear models --- ordinal classification variables --- association models --- correlation models --- minimum penalized ?-divergence estimator --- consistency --- asymptotic normality --- goodness-of-fit --- bootstrap distribution estimator --- thematic quality assessment --- relative entropy --- logarithmic super divergence --- robustness --- minimum divergence inference --- generalized renyi entropy --- minimum divergence methods --- robustness --- single index model --- model assessment --- statistical distance --- non-quadratic distance --- total variation --- mixture index of fit --- Kullback-Leibler distance --- divergence measure --- ?-divergence --- relative error estimation --- robust estimation --- information geometry --- centroid --- Bregman information --- Hölder divergence --- indoor localization --- robustness --- efficiency --- Bayesian nonparametric --- Bayesian semi-parametric --- asymptotic property --- minimum disparity methods --- Hellinger distance --- Berstein von Mises theorem --- measurement errors --- robust testing --- two-sample test --- misspecified hypothesis and alternative --- 2-alternating capacities --- composite hypotheses --- corrupted data --- least-favorable hypotheses --- Neyman Pearson test --- divergence based testing --- Chernoff Stein lemma --- compressed data --- Hellinger distance --- representation formula --- iterated limits --- influence function --- consistency --- asymptotic normality --- location-scale family --- n/a

Applied Econometrics

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ISBN: 9783038979265 / 9783038979272 Year: Pages: 222 DOI: 10.3390/books978-3-03897-927-2 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Mathematics
Added to DOAB on : 2019-06-26 08:44:06
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Although the theme of the monograph is primarily related to “Applied Econometrics”, there are several theoretical contributions that are associated with empirical examples, or directions in which the novel theoretical ideas might be applied. The monograph is associated with significant and novel contributions in theoretical and applied econometrics; economics; theoretical and applied financial econometrics; quantitative finance; risk; financial modeling; portfolio management; optimal hedging strategies; theoretical and applied statistics; applied time series analysis; forecasting; applied mathematics; energy economics; energy finance; tourism research; tourism finance; agricultural economics; informatics; data mining; bibliometrics; and international rankings of journals and academics.

Keywords

inflation --- postage stamps --- price recovery --- historical time series --- EGARCH --- FHA loan --- home mortgage --- foreclosure --- default and prepayment --- unobserved heterogeneity --- duration models --- competing risks --- earnings forecasts --- earnings announcements --- financial markets --- financial analysts --- nonparametric time series modeling --- nonlinearity --- unified time series algorithm --- exploratory diagnostics --- control environment --- budgetary system and strategies --- operational control --- company performance --- economic growth --- economic freedom --- foreign direct investment --- panel data --- cash payments --- efficiency --- denomination range --- JEL Classification --- E42 --- E58 --- managing of financial health --- risk of bankruptcy --- prediction methods --- post-communist countries --- Misery Index --- inflation --- unemployment --- Probit and Logit models --- Okun’s law --- multivariate regression models --- heavy-tailed data --- Mahalanobis distances --- maximum likelihood estimator --- independent multivariate Student distribution --- uncorrelated multivariate Student distribution --- derivatives market --- economic development --- Granger-causality tests --- vector error correction model (VECM) --- DOLS --- FMOLS --- income inequality --- economic growth --- middle income countries --- Granger causality test --- system GMM --- oil price --- exchange rate --- trade balance --- cointegration --- frequency domain causality --- Nigeria --- Fama-French factor model --- market microstructure --- trading behavior --- panel data factor model --- social network model --- risk spillover --- abnormal returns

Stochastic Processes: Theory and Applications

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ISBN: 9783039219629 / 9783039219636 Year: Pages: 216 DOI: 10.3390/books978-3-03921-963-6 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Mathematics --- Statistics
Added to DOAB on : 2020-01-07 09:08:26
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The aim of this special issue is to publish original research papers that cover recent advances in the theory and application of stochastic processes. There is especial focus on applications of stochastic processes as models of dynamic phenomena in various research areas, such as queuing theory, physics, biology, economics, medicine, reliability theory, and financial mathematics. Potential topics include, but are not limited to: Markov chains and processes; large deviations and limit theorems; random motions; stochastic biological model; reliability, availability, maintenance, inspection; queueing models; queueing network models; computational methods for stochastic models; applications to risk theory, insurance and mathematical finance.

Keywords

measure of information --- cumulative inaccuracy --- mutual information --- lower record values --- parabolic equation --- Cauchy problem --- Monte Carlo method --- unbiased estimator --- von-Neumann–Ulam scheme --- compound poisson insurance risk model --- expected discounted penalty function --- estimation --- Fourier transform --- Fourier-cosine series --- multidimensional birth-death process --- inhomogeneous continuous-time Markov chain --- rate of convergence --- one dimensional projection --- Wiener–Poisson risk model --- survival probability --- Nonparametric threshold estimation --- wet periods --- total precipitation volume --- asymptotic approximation --- extreme order statistics --- random sample size --- testing statistical hypotheses --- queueing systems --- rate of convergence --- non-stationary --- Markovian queueing models --- limiting characteristics --- queuing network --- retrials --- state-dependent marked Markovian arrival process --- wireless telecommunication networks --- time-dependent queue-length probability --- discrete-time Geo/D/1 queue --- closed-form solution --- Monte Carlo method --- quasi-Monte Carlo method --- Koksma-Hlawka inequality --- quasi-random sequences --- stochastic processes --- processor heating and cooling --- markovian arrival process --- phase-type service time distribution --- impatience --- Quasi-Birth-and-Death process --- matrix-geometric solution --- truncated distribution --- Markovian arrival process --- multi-class arrival processes --- product form --- equity-linked death benefits --- Fourier cosine series expansion --- guaranteed minimum death benefit --- option --- valuation --- Lévy process --- compound Poisson risk model --- generalized Gerber–Shiu discounted penalty function --- Laplace transform --- Dickson–Hipp operator --- recursive formula

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