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Ethical Aspects of Climate Engineering

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ISBN: 9783866448568 Year: Pages: VII, 158 p. DOI: 10.5445/KSP/1000028245 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Philosophy
Added to DOAB on : 2016-08-11 12:46:27
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This study investigates the ethical aspects of deploying and researching into so-called climate engineering methods, i.e. large-scale technical interventions in the climate system with the objective of offsetting anthropogenic climate change. The moral reasons in favour of and against R&D into and deployment of CE methods are analysed by means of argument maps. These argument maps provide an overview of the CE controversy and help to structure the complex debate.

Islamic Area Studies with Geographical Information Systems

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Book Series: New Horizons in Islamic Studies ISBN: 9780203401422 9780415332507 9780415665872 9781138010246 9781134320431 9781134320424 9781134320387 Year: DOI: 10.4324/9780203401422 Language: English
Publisher: Taylor & Francis
Subject: Political Science --- Science (General)
Added to DOAB on : 2019-11-08 11:21:20
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In this volume the contributors use Geographical Information Systems (GIS) to reassess both historic and contemporary Asian countries and traditionally Islamic areas. This highly illustrated and comprehensive work highlights how GIS can be applied to the social sciences. With its description of how to process, construct and manage geographical data the book is ideal for the non-specialist looking for a new and refreshing way to approach Islamic area studies.

Developments in Bovine Immunology - An Integrated View

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889196326 Year: Pages: 112 DOI: 10.3389/978-2-88919-632-6 Language: English
Publisher: Frontiers Media SA
Subject: Allergy and Immunology --- Medicine (General)
Added to DOAB on : 2016-08-16 10:34:25
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The world’s population is predicted to hit 9 Billion by 2050, and with it food demand is predicted to increase substantially. The World Bank estimates that cereal and meat production needs to increase by 50% and 85% respectively between 2000 and 2030 to meet demand, putting serious pressure on the global agricultural industry. Critical to meeting this demand for food are mechanisms to reduce the incidence of animal disease. With in excess of 1.3 billion cattle globally, the total cost of infectious diseases is difficult to estimate. However in North America alone, the cost is predicted to be $18 billion annually. Non-infectious diseases also account for another major impediment to the production capacity and welfare of animals as well as the economic sustainability of farming. However animal diseases have implications that spread far beyond the farm gate. Infectious agents can also contaminate the food chain, and potentially affect human health. Controlling diseases, through better preventative and treatment methods requires a detailed understanding of the immune response in livestock species. Multiple studies have identified associations between variation in immune genes and disease susceptibility, which potentially opens up new avenues to select animals with superior disease resistance. Detailed understanding of immunity in cattle is leading to the design of more effective vaccines. Furthermore, appreciation of the significant differences between rodent and human immune responses has also led to bovine models being developed for some human diseases. The publication of the bovine genome and the advent of next-generation sequencing technologies have facilitated a massive expansion in our knowledge of the immune response in cattle. As a result there has been an explosion of exciting research findings including in metagenomics and epigenetics. Recently, there has been a welcome move to integrate our emerging understanding of the immune response with detailed studies of other important physiological processes including nutrition and reproduction. The interactions between the reproductive system, nutrition and the immune system are of particular interest, since each places significant demands on the animal at various stages through the production cycle. The interplay between these morphologically diffuse systems involves widely distributed chemical signals in response to environmental input, and each system must interact for the normal functioning of the other. A comprehensive “systems” approach is improving our understanding of normal physiological interactions between these systems and furthermore, how dysregulation can lead to disease. The successful translation of bovine immunological research into improved treatments for animal disease requires tight interaction between diverse scientific and clinical disciplines including immunology, microbiology, endocrinology, physiology, nutrition, reproduction and clinical veterinary medicine. With so much recent progress in the field, we believe that it is valuable and well-timed to review the broad variety of the relevant studies that attempt to increase our understanding through comprehensive collaboration between these disciplines. We are looking forward to a wide and vivid discussion of developments in bovine immunology and related issues, and we expect that our readers profoundly benefit from new exciting insights and fruitful collaborations.

Umgebungskartenschätzung aus Sidescan-Sonardaten für ein autonomes Unterwasserfahrzeug

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Book Series: Karlsruher Schriften zur Anthropomatik / Lehrstuhl für Interaktive Echtzeitsysteme, Karlsruher Institut für Technologie ; Fraunhofer-Inst. für Optronik, Systemtechnik und Bildauswertung IOSB Karlsruhe ISSN: 18636489 ISBN: 9783731505419 Year: Volume: 26 Pages: XXV, 331 p. DOI: 10.5445/KSP/1000055793 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Computer Science
Added to DOAB on : 2019-07-30 20:01:57
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This work makes several contributions to the process of estimating elevation maps from side-scan sonar data: A new estimation method that recreates sonar measurements by pre-computed known sonar responses (so called kernels) and then derives a height profile from the kernels used. Additionally, a 3D method based on Markov Random Fields and a side-scan sonar simulation environment for arbitraty 3D scenes featuring different sonar modes and several terrain generators have been developed.

Gleisselektive Ortung von Schienenfahrzeugen mit bordautonomer Sensorik

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Book Series: Schriftenreihe / Institut für Mess- und Regelungstechnik, Universität Karlsruhe (TH) ISSN: 16134214 ISBN: 9783866441965 Year: Volume: 011 Pages: XVI, 158 p. DOI: 10.5445/KSP/1000007317 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:01:59
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In dieser Arbeit wird eine gleisselektive, bordautonome Ortungsplattform für Schienenfahrzeuge unter Verwendung diversitärer, redundanter Sensoren vorgestellt. Durch die Verwendung eines neuartigen Wirbelstrom-Sensorsystems in Kombination mit inertialer Sensorik, GPS und einer digitalen Streckenkarte werden die Anforderungen an eine sicherheitsrelevante Ortungsplattform erfüllt. Hierbei werden unterschiedliche Fusionsansätze hergeleitet und anhand realer Messdaten bewertend verglichen.

Producing and Analyzing Macro-Connectomes: Current State and Challenges

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889199815 Year: Pages: 139 DOI: 10.3389/978-2-88919-981-5 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Neurology
Added to DOAB on : 2016-01-19 14:05:46
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Construction of comprehensive and detailed brain regions neuroanatomical connections matrices (macro-connectomes) is necessary to understand how the nervous system is organized and to elucidate how its different parts interact. Macro-connectomes also are the structural foundation of any finer granularity approaches at the neuron classes and types (meso-connectomes) or individual neuron (micro-connectomes) levels. The advent of novel neuroanatomical methods, as well as combinations of classic techniques, form the basis of several large scale projects with the ultimate goal of producing publicly available connectomes at different levels. A parallel approach, that of systematic and comprehensive collation of connectivity data from the published literature and from publicly accessible neuroinformatics platforms, has produced macro-connectomes of different parts of the central nervous system (CNS) in several mammalian species. The emergence of these public platforms that allow for the manipulation of rich connectivity data sets and enable the construction of CNS macro-connectomes in different species may have significant and long lasting implications. Moreover, when these efforts are leveraged by novel statistical methods, they may influence our way of thinking about the brain. Hence, the present brain region-centric paradigm may be challenged by a network-centric one. Ultimately, these projects will provide the information and knowledge for understanding how different neuronal parts communicate and function, developing novel approaches to diseases and disorders, and facilitating translational efforts in neurosciences. With this Research Topic we bring together the current state of macro-connectome related projects including the large scale production of thousands of publicly available neuronatomical experiments, databases with tens of thousands of connectivity records collated from the published literature, and the newest methods for displaying and analyzing this information. This topic also includes a wide range of challenges and how they are addressed - from platforms designed to integrate connectivity data across different sources, species and CNS levels of organization, to languages specifically designed to use these data in models at different scales of resolution, to efforts of 3D reconstruction and data integration, and to approaches for extraction and representation of this knowledge. Finally, we address the present state of different efforts of meso-connectomes construction, and of computational modeling in the context of the

Inferenz von Kreuzungsinformationen aus Flottendaten

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Book Series: Schriftenreihe / Institut für Mess- und Regelungstechnik, Karlsruher Institut für Technologie ISSN: 16134214 ISBN: 9783731507215 Year: Volume: 37 Pages: XIX, 171 p. DOI: 10.5445/KSP/1000073704 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:01:57
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The next generation of driver assistance systems and highly automated driving functions are based on digital maps. In order to meet the high requirements on the correctness and up-to-dateness of this information, this work presents new automated methods to extract up-to-date map information from fleet data. The focus is on the inference of static intersection information from fleet data through machine learning and statistical methods.

Supercomputing Frontiers: 4th Asian Conference, SCFA 2018, Singapore, March 26-29, 2018, Proceedings

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Book Series: Theoretical Computer Science and General Issues ISBN: 9783319699523 9783319699530 Year: Volume: 10776 Pages: 293 DOI: https://doi.org/10.1007/978-3-319-69953-0 Language: English
Publisher: Springer Grant: National Supercomputing Centre (NSCC), Singapore
Subject: Computer Science
Added to DOAB on : 2018-07-20 15:24:25
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It constitutes the refereed proceedings of the 4th Asian Supercomputing Conference, SCFA 2018, held in Singapore in March 2018. Supercomputing Frontiers will be rebranded as Supercomputing Frontiers Asia (SCFA), which serves as the technical programme for SCA18. The technical programme for SCA18 consists of four tracks: Application, Algorithms & LibrariesProgramming System SoftwareArchitecture, Network/Communications & ManagementData, Storage & VisualisationThe 20 papers presented in this volume were carefully reviewed nd selected from 60 submissions.

Dual Specificity Phosphatases: From Molecular Mechanisms to Biological Function

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ISBN: 9783039216888 / 9783039216895 Year: Pages: 240 DOI: 10.3390/books978-3-03921-689-5 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
Added to DOAB on : 2019-12-09 11:49:16
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Dual specificity phosphatases (DUSPs) constitute a heterogeneous group of protein tyrosine phosphatases with the ability to dephosphorylate Ser/Thr and Tyr residues from proteins, as well as from other non-proteinaceous substrates including signaling lipids. DUSPs include, among others, MAP kinase (MAPK) phosphatases (MKPs) and small-size atypical DUSPs. MKPs are enzymes specialized in regulating the activity and subcellular location of MAPKs, whereas the function of small-size atypical DUSPs seems to be more diverse. DUSPs have emerged as key players in the regulation of cell growth, differentiation, stress response, and apoptosis. DUSPs regulate essential physiological processes, including immunity, neurobiology and metabolic homeostasis, and have been implicated in tumorigenesis, pathological inflammation and metabolic disorders. Accordingly, alterations in the expression or function of MKPs and small-size atypical DUSPs have consequences essential to human disease, making these enzymes potential biological markers and therapeutic targets. This Special Issue covers recent advances in the molecular mechanisms and biological functions of MKPs and small-size atypical DUSPs, and their relevance in human disease.

Cognitive Aspects of Human-Computer Interaction for GIS

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ISBN: 9783039215683 / 9783039215690 Year: Pages: 196 DOI: 10.3390/books978-3-03921-569-0 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Computer Science
Added to DOAB on : 2019-12-09 16:10:12
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The book is dealing with recent progress in human–computer interaction (HCI) related to geographic information science (GIS). The Editorial starts with an overview about the evolution of the Internet and first HCI concepts and stimulates recent HCI developments using 3D and 4D apps, running on all mobile devices with OS Android, iOS, Linus, and Windows. Eight research articles present the state-of-the-art in HCI–GIS-related issues, starting with gender and age differences in using indoor maps via the estimation of building heights from space to an efficient visualization method for polygonal data with dynamic simplification. The review article deals with progress and challenges on entity alignment of geographic knowledge bases.

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