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Biofilm-Based Nosocomial Infections

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ISBN: 9783038421351 9783038421368 Year: Pages: 238 DOI: 10.3390/books978-3-03842-136-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Added to DOAB on : 2016-05-12 12:14:31
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Abstract

Microbial biofilms have been implicated in a large number of acute and chronic infections, as well as in the failure of antibiotic treatment, particularly in hospitalized patients. In fact, the well-known persistence in the nosocomial environment of multidrug resistant microorganisms is believed to be highly promoted by the ability of the great majority of the involved bacterial and fungal species to adhere on living or abiotic surfaces, and to grow in sessile mode, to form single- or multi-species biofilms. In these communities, microbes grow encased in a hydrated matrix of extracellular polymeric substances produced by themselves and are well protected from the host immune response and the attack of antimicrobial molecules. Thus, the establishment of microbial biofilm communities on the mucosal and soft tissues of hospitalized patients, as well as on the surfaces of indwelling devices and medical instruments, is expected to have a great influence on the success of the antibiotic therapies against most of the bugs involved in nosocomial infections, being biofilm-growing bacteria and fungi much less susceptible to antibiotics.

Care Home Stories

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Book Series: Aging Studies ISBN: 9783837638059 9783839438053 Year: Language: English
Publisher: transcript Verlag Grant: Knowledge Unlatched - 101223
Subject: Social Sciences
Added to DOAB on : 2018-03-16 11:02:30
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Institutional care for seniors offers a cultural repository for fears and hopes about an aging population. Although enormous changes have occurred in how institutional care is structured, the legacies of the poor house still persist, creating panicked views of the nursing home as a dreaded fate. The paradoxical nature of a space meant to be both hospital and home offers up critical tensions for examination by age studies scholars. The essays in this book challenge stereotypes of institutional care for older adults, illustrate the changes that have occurred over time, and illuminate the continuities in the stories we tell about nursing homes.

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