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From Genes to Species: Novel Insights from Metagenomics

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889199754 Year: Pages: 229 DOI: 10.3389/978-2-88919-975-4 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Microbiology
Added to DOAB on : 2016-01-19 14:05:46
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Abstract

The majority of microbes in many environments are considered “as yet uncultured” and were traditionally considered inaccessible for study through the microbiological gold standard of pure culture. The emergence of metagenomic approaches has allowed researchers to access and study these microbes in a culture-independent manner through DNA sequencing and functional expression of metagenomic DNA in a heterologous host. Metagenomics has revealed an extraordinary degree of diversity and novelty, not only among microbial communities themselves, but also within the genomes of these microbes. This Research Topic aims to showcase the utility of metagenomics to gain insights on the microbial and genomic diversity in different environments by revealing the breadth of novelty that was in the past, largely untapped.

Microbiome Interplay and Control

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889455058 Year: Pages: 421 DOI: 10.3389/978-2-88945-505-8 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Microbiology
Added to DOAB on : 2019-01-23 14:53:42
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In complex systems, such as our body or a plant, the host is living together with thousands of microbes, which support the entire system in function and health. The stability of a microbiome is influenced by environmental changes, introduction of microbes and microbial communities, or other factors. As learned in the past, microbial diversity is the key and low-diverse microbiomes often mirror out-of-control situations or disease. It is now our task to understand the molecular principles behind the complex interaction of microbes in, on and around us in order to optimize and control the function of the microbial community – by changing the environment or the addition of the right microorganisms. This Research Topic focuses on studies (including e.g. original research, perspectives, mini reviews, and opinion papers) that investigate and discuss: 1) The role of the microbiome for the host/environmental system 2) The exchange and change of microbes and microbial communities (interplay) 3) The influence of external factors toward the stability of a microbiome 4) Methods, possibilities and approaches to change and control a system’s microbiome (e.g. in human or plant disease) 5) Experimental systems and approaches in microbiome research.The articles span the areas: human health and disease, animal and plant microbiomes, microbial interplay and control, methodology and the built environment microbiome.

Recent Discoveries in Evolutionary and Genomic Microbiology

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889196173 Year: Pages: 99 DOI: 10.3389/978-2-88919-617-3 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Microbiology
Added to DOAB on : 2016-08-16 10:34:25
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This collection represents certain discoveries that were made in evolutionary and genomic microbiology during the recent ten years. We attempted to shed light on topical issues of microbial evolution and microbiome biology. In our eyes, these articles are of an excellent quality and may be helpful both for casual readers and for specialists in the field.

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