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"Behinderung" im Dialog zwischen Recht und Humangenetik

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Book Series: Göttinger Schriften zum Medizinrecht ISBN: 9783863951504 Year: Pages: 157 DOI: 10.17875/gup2014-30 Language: German
Publisher: Universitätsverlag Göttingen
Subject: Medicine (General) --- Law
Added to DOAB on : 2014-03-15 11:41:59
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Modern medical technologies, especially the pre-implantation and prenatal diagnosis, have given the possibility of preventive dealing with the risks of physical or mental disabilities. On the other side there is the call for support and “inclusion” of people with disabilities. These opposing trends are critically analyzed and discussed in depth from a legally, genetic, as well as from a medical, social and ethical point of view.

Contemporary Bioethics: Islamic Perspective

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ISBN: 9783319184272 9783319184289 Year: Pages: 267 DOI: 10.1007/978-3-319-18428-9 Language: English
Publisher: Springer
Subject: Medicine (General) --- Philosophy --- Pharmacy and materia medica --- Biotechnology
Added to DOAB on : 2016-04-12 17:55:24
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This book combines Islamic textual analysis with juridical methodology to engage dominant secular bioethics in the Muslim healthcare institutions.It integrates Islamic textual resources with medical information in order to provide careful analyses of the political, economic and cultural terrains that are necessary for bioethicists to effectively promote social justice

The Challenge of Chance: A Multidisciplinary Approach from Science and the Humanities

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Book Series: The Frontiers Collection ISSN: 1612-3018 ISBN: 9783319262987 9783319263007 Year: Pages: 276 DOI: 10.1007/978-3-319-26300-7 Language: English
Publisher: Springer
Subject: Statistics
Added to DOAB on : 2017-01-24 17:28:09
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This book presents a multidisciplinary perspective on chance, with contributions from distinguished researchers in the areas of biology, cognitive neuroscience, economics, genetics, general history, law, linguistics, logic, mathematical physics, statistics, theology and philosophy. The individual chapters are bound together by a general introduction followed by an opening chapter that surveys 2500 years of linguistic, philosophical, and scientific reflections on chance, coincidence, fortune, randomness, luck and related concepts.A main conclusion that can be drawn is that, even after all this time, we still cannot be sure whether chance is a truly fundamental and irreducible phenomenon, in that certain events are simply uncaused and could have been otherwise, or whether it is always simply a reflection of our ignorance. Other challenges that emerge from this book include a better understanding of the contextuality and perspectival character of chance (including its scale-dependence), and the curious fact that, throughout history (including contemporary science), chance has been used both as an explanation and as a hallmark of the absence of explanation. As such, this book challenges the reader to think about chance in a new way and to come to grips with this endlessly fascinating phenomenon.

Genetische Individualität im Recht

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Book Series: Göttinger Schriften zum Medizinrecht ISBN: 9783863950996 Year: Pages: 168 DOI: 10.17875/gup2012-27 Language: German
Publisher: Universitätsverlag Göttingen
Subject: Medicine (General) --- Law
Added to DOAB on : 2013-03-17 04:22:14
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Die Entzifferung des Genoms und zuletzt die Entwicklung moderner Sequenzierungsverfahren lassen viele Menschen befürchten, dass dadurch ihre „Individualität“ verlorengehen könnte. Was damit genau gemeint ist, welches Selbstverständnis des Individuums dem zugrunde liegt und inwieweit die Sorge berechtigt ist, untersucht der vorliegende Band im interdisziplinären Diskurs zwischen Humangenetik und Recht. Die Beiträge resultieren aus einem interdisziplinären Workshop des Göttinger Instituts für Humangenetik in Kooperation mit dem Zentrum für Medizinrecht im Januar 2012. Ergänzende Beiträge sowohl aus humangenetischer als auch juristischer Perspektive verbreitern die Faktenbasis und geben einen vertieften Einblick in den aktuellen Sachstand.

Embryo Cleavage

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ISBN: 9789535135111 9789535135128 Year: Pages: 122 DOI: 10.5772/65555 Language: English
Publisher: IntechOpen
Subject: Anatomy
Added to DOAB on : 2019-10-03 07:51:50

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Embryo cleavage experiences a series of critical events and remarkable epigenetic modifications, especially morphological change and gene expression. The development of current assisted reproductive technology has created some new observations and novel discoveries in cleavage embryos. This book updates some new technologies and methods on the study of cleavage embryos to select high-quality embryos for transfer and improve embryo implantation and pregnancy. Major contents include embryo cleavage morphokinetics based on time-lapse imaging, gene expression of cleavage embryo and noninvasive assessment, and improving embryo cleavage technology. Thus, this book will greatly add new information for embryologists to select good-quality embryos for transfer to improve human embryo transfer pregnancy rate.

Genetic Diversity and Disease Susceptibility

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ISBN: 9781789842012 9781789842029 Year: Pages: 164 DOI: 10.5772/intechopen.72269 Language: English
Publisher: IntechOpen
Subject: Genetics
Added to DOAB on : 2019-10-03 07:51:52

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Polymorphism or variation in DNA sequence can affect individual phenotypes such as color of skin or eyes, susceptibility to diseases, and response to drugs, vaccines, chemicals, and pathogens. Especially, the interfaces between genetics, disease susceptibility, and pharmacogenomics have recently been the subject of intense research activity. This book is a self-contained collection of valuable scholarly papers related to genetic diversity and disease susceptibility, pharmacogenomics, ongoing advances in technology, and analytic methods in this field. The book contains nine chapters that cover the three main topics of genetic polymorphism, genetic diversity, and disease susceptibility and pharmacogenomics. Hence, this book is particularly useful to academics, scientists, physicians, pharmacists, practicing researchers, and postgraduate students whose work relates to genetic polymorphisms.

Cytogenetics - Past, Present and Further Perspectives

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ISBN: 9781838804053 9781838804060 9781838806439 Year: Pages: 172 DOI: 10.5772/intechopen.73451 Language: English
Publisher: IntechOpen
Subject: Genetics
Added to DOAB on : 2019-10-03 07:51:53

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Cytogenetics - Past, Present, and Further Perspectives discusses events that influenced the development of cytogenetics as a specialty within biology, with special attention paid to methodological achievements developed worldwide that have driven the field forward. Improvements to the resolution of chromosome analysis followed closely the introduction of innovative analytical technologies. In that sense, this book reviews and provides a brief account of the structure of chromosomes and stresses the high structural conservation in different species with an emphasis on aspects that require further research. However, it should be kept in mind that the future of cytogenetics will likely depend on improved knowledge of chromosome structure and function.

Data and Text Processing for Health and Life Sciences

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Book Series: Advances in Experimental Medicine and Biology ISBN: 9783030138455 Year: Pages: 98 DOI: 10.1007/978-3-030-13845-5 Language: English
Publisher: Springer
Subject: Computer Science --- Medicine (General)
Added to DOAB on : 2020-02-05 11:21:03
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This open access book is a step-by-step introduction on how shell scripting can help solve many of the data processing tasks that Health and Life specialists face everyday with minimal software dependencies. The examples presented in the book show how simple command line tools can be used and combined to retrieve data and text from web resources, to filter and mine literature, and to explore the semantics encoded in biomedical ontologies. To store data this book relies on open standard text file formats, such as TSV, CSV, XML, and OWL, that can be open by any text editor or spreadsheet application. The first two chapters, Introduction and Resources, provide a brief introduction to the shell scripting and describe popular data resources in Health and Life Sciences. The third chapter, Data Retrieval, starts by introducing a common data processing task that involves multiple data resources. Then, this chapter explains how to automate each step of that task by introducing the required commands line tools one by one. The fourth chapter, Text Processing, shows how to filter and analyze text by using simple string matching techniques and regular expressions. The last chapter, Semantic Processing, shows how XPath queries and shell scripting is able to process complex data, such as the graphs used to specify ontologies. Besides being almost immutable for more than four decades and being available in most of our personal computers, shell scripting is relatively easy to learn by Health and Life specialists as a sequence of independent commands. Comprehending them is like conducting a new laboratory protocol by testing and understanding its procedural steps and variables, and combining their intermediate results. Thus, this book is particularly relevant to Health and Life specialists or students that want to easily learn how to process data and text, and which in return may facilitate and inspire them to acquire deeper bioinformatics skills in the future.

Dilated Cardiomyopathy

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ISBN: 9783030138646 Year: Pages: 241 DOI: 10.1007/978-3-030-13864-6 Language: English
Publisher: Springer
Subject: Biology --- Medicine (General)
Added to DOAB on : 2020-02-05 11:21:10
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This open access book presents a comprehensive overview of dilated cardiomyopathy, providing readers with practical guidelines for its clinical management. The first part of the book analyzes in detail the disease’s pathophysiology, its diagnostic work up as well as the prognostic stratification, and illustrates the role of genetics and gene-environment interaction. The second part presents current and future treatment options, highlighting the importance of long-term and individualized treatments and follow-up. Furthermore, it discusses open issues, such as the apparent healing phenomenon, the early prognosis of arrhythmic events or the use of genetic testing in clinical practice. Offering a multidisciplinary approach for optimizing the clinical management of DCM, this book is an invaluable aid not only for the clinical cardiologists, but for all physicians involved in the care of this challenging disease.

DNA Replication - Current Advances

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ISBN: 9789533075938 Year: Pages: 710 DOI: 10.5772/791 Language: English
Publisher: IntechOpen
Subject: Genetics
Added to DOAB on : 2019-10-03 07:51:48

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The study of DNA advanced human knowledge in a way comparable to the major theories in physics, surpassed only by discoveries such as fire or the number zero. However, it also created conceptual shortcuts, beliefs and misunderstandings that obscure the natural phenomena, hindering its better understanding. The deep conviction that no human knowledge is perfect, but only perfectible, should function as a fair safeguard against scientific dogmatism and enable open discussion. With this aim, this book will offer to its readers 30 chapters on current trends in the field of DNA replication. As several contributions in this book show, the study of DNA will continue for a while to be a leading front of scientific activities.

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