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Biological Potential and Medical Use of Secondary Metabolites

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ISBN: 9783039211876 9783039211883 Year: Pages: 284 DOI: 10.3390/books978-3-03921-188-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Chemistry (General)
Added to DOAB on : 2019-08-28 11:21:27
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Abstract

Many macro and micro species, from terrestrial and aquatic environments, produce structurally unique compounds and, in many countries, still are the primary sources of medicines. In fact, secondary metabolites are an important source of chemotherapeutic agents but are also lead compounds for synthetic modification and the optimization of biological activity. Therefore, the exploitation of secondary metabolites, or their inspired synthetic compounds, offers excellent opportunities for the pharmaceutical industry. This Medicines Special Issue focuses on the great potential of secondary metabolites for therapeutic application. The Special Issue contains 16 articles reporting relevant experimental results, and an overview of bioactive secondary metabolites, their biological effects, and new methodologies that improve and accelerate the process of obtained lead compounds with regard to new drug development. We would like to thank all 83 authors, from all over the world, for their valuable contributions to this Special Issue.

Keywords

Juniperus --- secondary metabolites --- diterpenes --- flavonoids --- lignans --- cytotoxic --- antitumor --- antibacterial --- amentoflavone --- deoxypodophyllotoxin --- frankincense --- Boswellia --- cembranoids --- cneorubenoids --- boswellic acids --- molecular docking --- Scabiosa --- flavonoids --- iridoids --- pentacyclic triterpenoids --- antioxidant --- anti-inflammatory --- antibacterial --- anticancer --- Cordyceps militaris --- xanthine oxidase --- antioxidant --- antibacterial --- cordycepin --- GC-MS --- Artemisia species --- Artemisia vachanica --- artemisinin --- HPLC-PAD --- Tajikistan --- Malus x domestica --- Tuscany --- ancient varieties --- nutraceutics --- antioxidants --- polyphenols --- sugars --- pectin --- defensins --- secondary metabolites --- plant defense --- antimicrobial and anticancer activity --- medicine --- innate immunity --- cannabis --- cannabinoids --- therapeutics --- toxicology --- analytical determination --- legalization --- natural products --- biosynthetic gene clusters --- secondary metabolites --- antiSMASH --- Mitragyna speciosa --- kratom --- secondary metabolites --- therapeutic uses --- toxicology --- analysis --- Maytenus chiapensis --- Celastraceae --- quinonemethide triterpenoids --- pristimerin --- tingenone --- HPLC-PDA --- Ocimum sanctum --- Lamiaceae --- (-)-rabdosiin --- cytotoxic activity --- triterpenoids --- phenolic derivatives --- nanoemulsion --- essential oils --- vector control --- infectious diseases --- TCM --- phytochemistry --- LC-MS/MS --- antioxidant activity --- ABTS --- DPPH --- FRAP --- ascorbic acid --- EGCG --- total phenolics --- antimicrobial activity --- sargaquinoic acid --- sarganaphthoquinoic acid --- antiplasmodial --- malaria --- PPAR-? --- sargahydroquinoic acid --- sarganaphthoquinoic acid --- sargachromenoic acid --- inflammation --- bowel diseases --- secondary metabolites --- biological activities --- medicinal applications --- plants --- seaweeds

Medicinal Plants and Natural Product Research

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ISBN: 9783039281183 9783039281190 Year: Pages: 231 DOI: 10.3390/books978-3-03928-119-0 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Plant Sciences
Added to DOAB on : 2020-04-07 23:07:08
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Abstract

The book entitled Medicinal Plants and Natural Product Research describes various aspects of ethnopharmacological uses of medicinal plants; extraction, isolation, and identification of bioactive compounds from medicinal plants; various aspects of biological activity such as antioxidant, antimicrobial, anticancer, immunomodulatory activity, etc., as well as characterization of plant secondary metabolites as active substances from medicinal plants.

Keywords

Chrysanthemum coronarium L. --- aerial parts --- caffeoylquinic acids --- Malian medicinal plants --- Biophytum umbraculum --- Burkea africana --- Lannea velutina --- Terminalia macroptera --- medicinal plants --- traditional knowledge --- Eastern Himalayas --- mountain plants --- ethnobotany --- ethnopharmacology --- bioprospecting --- antibiotic resistance --- antimicrobial --- mechanism of action --- plant metabolite --- saline habitats --- secondary metabolites --- adaptation --- different solvents --- antibiotic resistance --- antimicrobial activity --- cytotoxicity --- ethnobotany --- Eucalyptus --- natural products --- Pseudomonas aeruginosa --- stingless bees --- Tetragonula --- traditional medicine --- basil varieties --- essential oil --- GC-MS --- harvest --- cluster analysis --- antimicrobial --- antioxidants --- medicinal plants --- BHT --- Ficus hirta --- Moraceae --- carboline alkaloids --- sesquiterpenoids --- flavonoids --- antifungal --- phytochemicals --- Nirgundi --- chaste tree --- antibacterial --- free radical --- scavenger --- oxidative stress --- P. alliaceae --- P. niruri --- S. reticulata --- UPLC --- TQ-ESI-MS --- proanthocyanidins --- mass spectrometry --- antioxidant --- cytotoxicity --- Moringa oleifera --- DPPH --- antioxidant activity --- oxidative stress --- sickle cell anemia --- Ophiopogon --- Liriope --- rbcL --- DNA barcoding --- high-resolution melt curve (HRM) analysis --- allergy --- inflammation --- mast cells --- Immulina® --- immunLoges® --- anthracene derivatives --- antimicrobial --- Asphodelus --- ethnomedicine --- skin diseases --- plant-food --- processing --- nutraceuticals --- inflammation --- health --- Arbutus unedo L. --- ?-glucosidase --- catechin --- HPLC --- NMR --- activity --- bioproduct --- Brunfelsia --- Amazonian --- Ecuador --- ethnobotanic --- ayahuasca --- validation --- drug discovery --- scopoletin

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