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Nonsteroidal Anti-Inflammatory Drugs

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ISBN: 9789535134435 9789535134442 Year: Pages: 162 DOI: 10.5772/65816 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:50

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This book intends to provide the reader with a comprehensive overview about the state of the art regarding the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in physical and rehabilitation medicine and the study of the pharmacodynamics of existing and newly introduced NSAIDs in the management of pain and inflammation. It will also elaborate and refine already known knowledge on the mechanism(s) of nonsteroidal anti-inflammatory agents. This book may provide additional knowledge about the design and development of new drug delivery systems loaded with NSAIDs potentially useful in the treatment of chronic inflammatory-based diseases following circadian cycle, uses of NSAIDs as a source of medicinal plants, and the adverse effects and drug interactions of the nonsteroidal anti-inflammatory drugs.

Systemic Sclerosis

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ISBN: 9789535135470 9789535135487 Year: Pages: 216 DOI: 10.5772/63286 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:50

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Systemic sclerosis is a rare autoimmune disease characterized by immunological alterations, small vessel vasculopathy, and skin and other organ fibrosis. Despite progress in the knowledge of pathogenic steps and therapeutic options, when compared with other rheumatic conditions, it shows the lowest life expectancy rate. Early diagnosis is important as early treatment could lead to better outcomes. Great progress has been made in the treatment of specific symptoms; however, there are still no disease-modifying drugs that are able to control the overall disease activity satisfactorily. This book covers the latest knowledge in systemic sclerosis from pathophysiology to clinical presentation and management. Hopefully, this book will be a useful resource to students, residents, rheumatologists, dermatologist, and anyone interested in this fascinating disease.

Allergen

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ISBN: 9789535135678 9789535135685 Year: Pages: 160 DOI: 10.5772/65229 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:50

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Allergy is a main problem of public health in the world. Many people in all countries are suffering from this problem. Some diseases (i.e. allergic rhinitis, allergic asthma, food allergy, urticaria, eczema, etc.) have allergic reaction pathophysiology, and with control of allergic mechanisms, these diseases can be controlled and cured. The current book entitled Allergen has focused on allergy, mechanism, diagnosis, treatment, and other related problems. Chapters of the book have good data on allergy-based medical sciences and would be a benefit for all researchers in immunology, allergy, and asthma fields. Current discussions would be useful for prevention, diagnosis, treatment, and follow-up of atopic patients. We hope these chapters could be a new approach in immunotherapy of allergic diseases and help in the progress of healthy system.

Physiology and Pathology of Immunology

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ISBN: 9789535136910 9789535136927 9789535140108 Year: Pages: 264 DOI: 10.5772/66541 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:50

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Having authored and published many successful and important textbooks in primary immunodeficiencies and cancer immunology, the editor of Physiology and Pathology of Immunology has ensured the high standard of writing and authenticity of the contents in this publication. The current book covers a spectrum of high-impact knowledge on the complex interplay between the environment, genes, and immunity that culminates in a generation of notorious processes of immune-related disorders. From evolution of regulatory T-cell function, gigantic cytokine networks within the human body to host-pathogen interactions of Chagas disease and Parkinson's disease, the Physiology and Pathology of Immunology goes further to decipher new codes from the immunity enigma, making it essential for experienced and new learners who wish to join the galaxy of modern immunology.

Vasculitis In Practice - An Update on Special Situations - Clinical and Therapeutic Considerations

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ISBN: 9781789236989 9781789236996 Year: Pages: 112 DOI: 10.5772/intechopen.69793 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:52

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""Vasculitis"" describes an inflammatory process that involves the blood vessels and contributes to vascular damage. Autoimmunity, infections, drugs, and malignancies have been considered among potential etio-pathogenic factors. In vasculitis, the inflammation might develop in either a systemic or an organ-specific form and might exist as an independent pathology ""primary vasculitis"" or as a presentation of an existing primary pathology, that is, ""secondary vasculitis"". This book Vasculitis In Practice-An Update on Special Situations - Clinical and Therapeutic Considerations unlike many publications in the field, uses a different evidence-based approach to organ-specific vascular inflammatory diseases. The authors highlighted the unmet needs from the 1994 Chapel Hill Consensus Conference introducing the latest clinically relevant definitions for the different forms of vasculitis revised in 2012. The identification, classification, and management of kidney disease with different types of vasculitis with an evidence-based update on proposed therapeutic strategies are presented in this publication.

Celiac Disease - From the Bench to the Clinic

Authors: ---
ISBN: 9781789850499 9781789850505 Year: Pages: 100 DOI: 10.5772/intechopen.73847 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:52

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Celiac disease (CD) occurs in about 1% of people worldwide. Diagnosis rates are increasing due to a true rise in incidence, rather than increased awareness and detection. CD affects genetically susceptible individuals who are triggered by the ingestion of gluten. The disease has many clinical manifestations, ranging from severe to minimally symptomatic or non-symptomatic presentations. Diagnosis requires the presence of duodenal chronic inflammation, and most patients have circulating antibodies against tissue transglutaminase. Our understanding of the basic and clinical aspects of CD increases, which is as a major health problem of almost global occurrence. Case finding, distinguishing CD from other gluten-sensitive conditions, better care, and balanced use of resources are the current challenges.

Chronic Autoimmune Epithelitis - Sjogren's Syndrome and Other Autoimmune Diseases of the Exocrine Glands

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Book Series: Rheumatology ISSN: 26319233 ISBN: 9781789852110 9781789852127 9781789854152 Year: Volume: 3 Pages: 120 DOI: 10.5772/intechopen.73892 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:53

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Epithelial tissue does not spring to mind as an obvious source of autoimmune phenomena. Yet, genetic predisposition and influence of various environmental and epigenetic factors may lead to epithelium becoming a springboard for the development of autoimmune diseases, such as Sjögren’s syndrome, primary biliary cholangitis, autoimmune pancreatitis, or IgG4-related diseases. This book is intended as an introduction to the problem of “autoimmune epithelitis” and diseases closely related to the immune disturbances of the epithelium, with special emphasis on those affecting exocrine glands. Both theoretical and practical knowledge, presented by authors from a wide range of medical specialties, should be of help for medical professionals who have to deal with this difficult problem in their daily practice.

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