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Frontiers in Toxicity and Functionalization of Nanomaterials

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ISBN: 9783038427360 9783038427353 Year: Pages: 182 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General)
Added to DOAB on : 2018-03-16 13:37:44
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Over the last decade, various nanomaterials (NMs) have attracted tremendous attention with the incredible development in nanoscience and nanotechnology. Some NMs are explored increasingly for biomedical applications, including drug delivery carriers, imaging probes, antimicrobial agents, biosensors, and tissue engineering scaffolds. However, the in vitro and in vivo toxicities of NMs related to oxidative stress are the main obstacles to use them in biomedical fields. One of the most promising strategies to address these obstacles is functionalizing NMs with biocompatible molecules or materials. In this Special Issue, we are especially interested in manuscripts that advance the understanding of the interaction of NMs with cells, such as cellular responses to NMs, intracellular behaviors of NMs, therapeutic and imaging potentials of NMs, as well as the functionalization of NMs through coating, patterning and hybridization with other biomolecules for multifaceted biomedical applications.

Stimuli-Responsive Gels

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ISBN: 9783038972105 9783038972112 Year: Pages: 288 DOI: 10.3390/books978-3-03897-211-2 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General) --- Chemical Technology
Added to DOAB on : 2018-10-11 10:12:55
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ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms.[Although the technological and scientific importance of functional polymers have been well established over the last few decades, the most recent focus that has attracted much attention concerns stimuli-responsive polymer gels. These materials are of particular interest due to their abilities to respond to internal and/or external chemo-physical stimuli. Aside from the scientific challenges of designing stimuli-responsive polymer gels, the main technological interests concern numerous applications, ranging from catalysis in microsystem technology and chemo-mechanical actuators to sensors. This Special Issue includes seventeen papers covering a wide range of subjects including thermo- and pH-responsive hydrogels, functionalized materials, supramolecular stimuli-responsive structures, composite hydrogels, sensors, and biomedical applications. Together, these contributions not only provide an excellent overview of the current state-of-the-art in the field but also point out exciting challenges and opportunities for future work. In a number of reviews the most recent findings on “Stimuli-Responsive Gels” are compiled in this book supplemented by original contributions.

Electrochemically Engineering of Nanoporous Materials

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ISBN: 9783038972686 9783038972693 Year: Pages: 158 DOI: 10.3390/books978-3-03897-269-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General)
Added to DOAB on : 2018-10-10 11:46:51
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ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms.Electrochemical engineering of nanoporous materials is a cost-effective and facile synthesis approach that enables the production of a range of nanoscale materials with controllable dimensions and properties. Recent decades have witnessed extensive research activity into the advanced engineering of nanoporous materials, from fundamental studies to applied science. These nanomaterials offer a set of unique and exclusive advantages for a wealth of applications, including catalysis, energy storage and harvesting, electronics, photonics, sensing, templates, and membranes.This Special Issue is dedicated to recent research advances in electrochemical engineering of nanoporous materials and their application across several disciplines and research fields. The broad and interdisciplinary applicability of these nanomaterials will be of profound and immediate interest for a broad audience, ranging from physicists, chemists, engineers, materials scientists, bioengineers, and nanomedicine experts.

Stimuli-Responsive Polymer Systems—Recent Manufacturing Techniques and Applications

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ISBN: 9783039214839 9783039214846 Year: Pages: 92 DOI: 10.3390/books978-3-03921-484-6 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2019-12-09 11:49:15
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Stimuli-responsive polymer systems can be defined as functional materials that show physical or chemical property changes in response to external stimuli such as temperature, radiation, chemical agents, pH, mechanical stress, and electric and magnetic fields. Recent developments in manufacturing techniques have facilitated the production of a wide range of stimuli-responsive polymer systems, such as micro- and nanoscale structures, with potential applications in soft sensors and actuators, smart textiles, soft robots, and artificial muscles. This book brings together the recent progress in manufacturing techniques, with particular emphasis on 3D and 4D printing and applications of stimuli-responsive polymer systems in biomedicine and soft robotics.

Nanocelluloses: Synthesis, Modification and Applications

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ISBN: 9783039287840 / 9783039287857 Year: Pages: 142 DOI: 10.3390/books978-3-03928-785-7 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- Biotechnology
Added to DOAB on : 2020-06-09 16:38:57
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Nanocelluloses: Synthesis, Modification and Applications is a book that provides some recent enhancements of various types of nanocellulose, mainly bacterial nanocellulose, cellulose nanocrystals and nanofibrils, and their nanocomposites. Bioactive bacterial nanocellulose finds applications in biomedical applications, https://doi.org/10.3390/nano9101352. Grafting and cross-linking bacterial nanocellulose modification emerges as a good choice for improving the potential of bacterial nanocellulose in such biomedical applications as topical wound dressings and tissue-engineering scaffolds, https://doi.org/10.3390/nano9121668. On the other hand, bacterial nanocellulose can be used as paper additive for fluorescent paper, https://doi.org/10.3390/nano9091322, and for the reinforcement of paper made from recycled fibers, https://doi.org/10.3390/nano9010058. Nanocellulose membranes are used for up-to-date carbon capture applications, https://doi.org/10.3390/nano9060877. Nanocellulose has been applied as a novel component of membranes designed to address a large spectrum of filtration problems, https://doi.org/10.3390/nano9060867. Poly(vinyl alcohol) (PVA) and cellulose nanocrystals (CNC) in random composite mats prepared using the electrospinning method are widely characterized in a large range of physical chemical aspects, https://doi.org/10.3390/nano9050805. Similarly, physical chemical aspects are emphasized for carboxylated cellulose nanofibrils produced by ammonium persulfate oxidation combined with ultrasonic and mechanical treatment, https://doi.org/10.3390/nano8090640. It is extraordinary how nanocellulose can find application in such different fields. Along the same lines, the contributions in this book come from numerous different countries, confirming the great interest of the scientific community for nanocellulose.

Sol-Gel Chemistry Applied to Materials Science

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ISBN: 9783039213535 9783039213542 Year: Pages: 216 DOI: 10.3390/books978-3-03921-354-2 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Chemistry (General)
Added to DOAB on : 2019-12-09 11:49:15
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Sol–gel technology is a contemporary advancement in science that requires taking a multidisciplinary approach with regard to its various applications. This book highlights some applications of the sol–gel technology, including protective coatings, catalysts, piezoelectric devices, wave guides, lenses, high-strength ceramics, superconductors, synthesis of nanoparticles, and insulating materials. In particular, for biotechnological applications, biomolecules or the incorporation of bioactive substances into the sol–gel matrix has been extensively studied and has been a challenge for many researchers. Some sol–gel materials are widely applied in light-emitting diodes, solar cells, sensing, catalysis, integration in photovoltaic devices, and more recently in biosensing, bioimaging, or medical diagnosis; others can be considered excellent drug delivery systems. The goal of an ideal drug delivery system is the prompt delivery of a therapeutic amount of the drug to the proper site in the body, where the desired drug concentration can be maintained. The interactions between drugs and the sol–gel system can affect the release rate. In conclusion, the sol–gel synthesis method offers mixing at the molecular level and is able to improve the chemical homogeneity of the resulting composite. This opens new doors not only regarding

Keywords

sol-gel method --- Fourier transform infrared spectroscopy (FTIR) analysis --- bioactivity --- biocompatibility --- sol–gel method --- organic-inorganic hybrids --- chlorogenic acid --- cytotoxicity --- biocompatibility --- silsesquioxanes --- thiol-ene click reaction --- in situ water production --- hydrophobic coatings --- cotton fabric --- paper --- NMR --- wettability --- sol-gel --- hollow sphere --- 1D structure --- sol-gel --- thin-disk laser --- Yb-doped glasses --- aluminosilicate glasses --- photoluminescence --- ultrasonic spray deposition --- tungsten oxide --- lithium lanthanum titanium oxide --- conformal coating --- Li-ion batteries --- sol-gel technique --- biomaterials --- cell proliferation --- cell cycle --- one transistor and one resistor (1T1R) --- organic thin-film transistor (OTFT) --- resistive random access memory (RRAM) --- sol-gel --- lithium-ion battery --- LiMnxFe(1?x)PO4 --- carbon coating --- pseudo-diffusion coefficient --- potential step voltammetry --- electrochemical impedance spectroscopy --- sol-gel --- oxyfluoride glass-ceramics --- nanocrystal --- optical properties --- sol-gel method --- SiO2–based hybrids --- poly(?-caprolactone) --- TG-DSC --- TG-FTIR --- X-ray diffraction analysis --- computer-aided design (CAD) --- mechanical analysis --- finite element analysis (FEA) --- composites --- organic–inorganic hybrid materials --- biomedical applications --- metal oxides --- multi-layer --- surface plasmon resonance --- optical sensors --- computer-aided design (CAD) --- mechanical analysis --- finite element analysis (FEA) --- composites --- hybrid materials --- biomedical applications

Electrospun Nanofibers for Biomedical Applications

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ISBN: 9783039287741 / 9783039287758 Year: Pages: 308 DOI: 10.3390/books978-3-03928-775-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General)
Added to DOAB on : 2020-06-09 16:38:57
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Electrospinning is a versatile and effective technique widely used to manufacture nanofibrous structures from a diversity of materials (synthetic, natural or inorganic). The electrospun nanofibrous meshes’ composition, morphology, porosity, and surface functionality support the development of advanced solutions for many biomedical applications. The Special Issue on “Electrospun Nanofibers for Biomedical Applications” assembles a set of original and highly-innovative contributions showcasing advanced devices and therapies based on or involving electrospun meshes. It comprises 13 original research papers covering topics that span from biomaterial scaffolds’ structure and functionalization, nanocomposites, antibacterial nanofibrous systems, wound dressings, monitoring devices, electrical stimulation, bone tissue engineering to first-in-human clinical trials. This publication also includes four review papers focused on drug delivery and tissue engineering applications.

Keywords

sol-gel --- electrospinning --- hydroxyapatite --- nanofiber --- antibacterial --- titanium --- antibacterial coatings --- electrospinning --- nanocomposite coatings --- TiO2 photocatalytic --- orthopedic infections --- electrospinning --- 3D printing --- nanofibers --- encapsulation --- protein diffusion --- in vivo tissue engineering --- immuno-isolation --- transplantation --- electrospinning --- sputtering --- drug delivery --- wound dressing --- biocompatibility --- tissue engineering --- biomimetic scaffolds --- gelatin --- electrospinning --- micromolding --- biomaterials --- poly(lactic acid) (PLLA) --- bioactive glass --- scaffolds --- electrospinning --- composite fibres --- bone regeneration --- poly(vinylidene fluoride) --- composite nanofiber --- piezoelectricity --- antioxidant activity --- well-aligned nanofibers --- P(VDF-TrFE) --- piezoelectric nanogenerator --- preosteoblasts electrospinning --- silicone modified polyurethane nanofibers --- physical properties --- cell attachment --- cell proliferation --- cytotoxicity --- biopolymers --- packaging --- pharmaceutical --- biomedical --- electrospinning --- alginate --- gelatin fibers --- ZnO particles --- antibacterial activity --- electrospinning --- nanofibers --- fabrication --- therapeutics --- biomedical applications --- antibody immobilization --- electrospun nanofibers --- TNF-? capture --- human articular chondrocytes --- rheumatoid arthritis --- nanofibers --- microfluidic chip --- electrospinning --- live assay --- hepatocellular carcinoma cells --- PLA95 --- biocompatibility --- guided tissue regeneration (GTR) --- electrospinning --- electrospun fiber mats --- mechanobiology --- glioblastoma --- biomaterials --- finite element modeling --- electrospun nanofibers --- cancer treatment --- drug release --- nanomedicine --- biocompatible polymers --- hyperthermia

Biomedical Applications of Nanoparticles

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ISBN: 9783039285426 / 9783039285433 Year: Pages: 366 DOI: 10.3390/books978-3-03928-543-3 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General)
Added to DOAB on : 2020-06-09 16:38:57
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This book provides an overview of the design and physico-chemical properties of nanoparticles developed for biomedical applications such as targeting and detection of pathologies, nanovectorization of drugs, radiosensitization, metal detection, and nanocomposite implants. The considerations necessary when developing a new nanomedicine are also developed, including toxicological investigation, biodistribution, and efficacy. This book provides an accurate and current representation of the field by addressing the promises and hurdles of nanomedicine via 20 different pertinent studies. Covering a wide range of areas, this book is an excellent partner for physico-chemists, doctors, pharmacologists, and biochemists working on nanosciences dedicated to medicine, both in industry and in academia.

Keywords

curcumin --- mitoxantrone --- synergism --- PEG --- chitosan nanoparticles --- hybrid Fe-Si nanoparticles --- laser pyrolysis --- Caco2 cells --- cytotoxicity --- oxidative stress --- upconversion nanoparticles --- nanocarriers --- drug delivery --- gene delivery --- photolysis --- cancer imaging --- cytoreduction surgery --- fluorescent nanoparticle --- near-infrared --- short-wave infrared --- Candida glabrata --- extracellular --- mycosynthesis --- MIC --- MBC --- MFC --- membrane integrity --- TEM --- FTIR --- surface-enhanced Raman spectroscopy (SERS) --- Ag-film --- Hg2+ ions detection --- SERS sensor --- nanocomposites --- medical devices --- middle ear prosthesis --- silver nanoparticles --- biocompatibility --- thermoplastic polymer --- dihydroartemisinin --- liposomes --- autophagy --- apoptosis --- breast cancer --- surface-enhanced Raman scattering (SERS) --- metal-enhanced fluorescence (MEF) --- dual functional imaging nanoprobe --- UiO-66 --- nanoparticles --- glioblastoma --- biocompatibility --- drug delivery --- alginate --- chitosan --- layer-by-layer --- magnetic nanoparticles --- drug delivery --- cancer --- curcumin --- lignin --- nanoparticle --- protein --- nanocellulose --- fibril --- enzyme --- heat --- self-assembly --- cross-link --- antibiotics --- nanoparticles --- biogenic nanoparticles --- antimicrobial --- antibiotic resistance --- multidrug resistant (MDR) microorganisms --- plasma --- nanomaterials --- nanomaterial synthesis --- plasma liquid Interactions --- non-thermal plasma --- biomedical applications --- core-shell nanoparticles --- biocompatible --- drug delivery --- anticancer --- SERS --- histamine --- nanostars --- nanophotonics --- computational electromagnetism --- surface enhanced Raman scattering --- SERS --- finite element method --- density functional theory calculations --- cell labeling --- cancer --- iron oxide superparamagnetic nanoparticles --- trans-resveratrol derivative --- drug delivery --- glioma --- gold nanoparticles --- radiosensitization --- thioredoxin reductase --- radiation --- prognosis --- biochemical mechanism --- nanodiamond --- targeted nanoparticles --- in vivo application --- cancer cell targeting --- antimiR --- nano-bio interaction

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