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Biological Activities of Alkaloids: From Toxicology to Pharmacology

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ISBN: 9783039289271 / 9783039289288 Year: Pages: 270 DOI: 10.3390/books978-3-03928-928-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2020-06-09 16:38:57
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Abstract

Natural products are increasingly attracting attention from both basic and applied science. Plant secondary metabolites, especially alkaloids, are receiving interest from a wide range of researchers due to their biological activity. They are produced to protect plants from diseases and herbivores. Therefore, they reveal a toxic activity that affects organisms at various levels of biological organization. A growing amount of research is proving their antimicrobial, antifungal, insecticidal, and anticancer activities. That makes them applicable in various fields from medicine, to pharmacology, veterinary, and toxicology, to crop protection. This Special Issue of Toxins, “Biological Activities of Alkaloids: From Toxicology to Pharmacology"", collects 15 manuscripts describing the ecological, biological, pharmacological, and toxicological effects as well as structural and analytical aspects of plant alkaloids, their mode of action, and possible application in veterinary, medicine, and plant protection. These studies prove the potential for alkaloid application in various areas of science.

Keywords

Arecoline --- lung cancer cells --- mAchR3 --- EGFR --- SRC --- FAK --- dehydrocrenatidine --- neuropathic pain --- voltage-gated sodium channels --- Solanum melongena L. --- malonylated form --- glycoalkaloids --- secondary metabolites --- solasonine --- solamargine --- malonyl-solamargine --- acetylcholinesterase --- antioxidant --- Ovarian cancer --- Rutidea parviflora --- Palmatine --- Apoptosis --- chanoclavine --- toxicology --- subchronic feeding study --- acute toxicity --- endophyte --- Epichloë --- plant secondary metabolites --- glycoalkaloids --- insect heart --- beetles --- insect --- Tenebrio molitor --- Radix Aconiti Lateralis preparations --- short-term and long-term usage --- di-ester diterpenoid alkaloids --- mono-ester diterpenoid alkaloids --- biodistribution --- ergot alkaloids --- livestock --- reproduction --- isoquinoline alkaloids --- antimicrobial activity --- Chelidonium majus --- cytotoxicity --- apoptosis --- sanguinarine --- berberine --- Chelidonium majus --- Berberis thunbergii --- leukemia --- anticancer --- natural products --- alkaloids --- plant secondary metabolites --- ?-carboline --- Staphylococcus aureus --- antimicrobial activity --- cytotoxicity --- acid-sensing ion channel subtype 1a --- bisbenzylisoquinoline alkaloid --- lindoldhamine --- nociception --- inflammation --- isoquinoline alkaloids --- HPLC-DAD --- cytotoxic activity --- Mahonia aquifolia --- Meconopsis cambrica --- Corydalis lutea --- Dicentra spectabilis --- Fumaria officinalis --- Macleaya cordata --- alkaloids --- natural sources --- anticancer --- antibacterial --- antiviral --- antifungal --- Curine --- alkaloid --- macrophage --- neutrophil --- lipopolysaccharide --- n/a

Medicinal Plants and Natural Product Research

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ISBN: 9783039281183 9783039281190 Year: Pages: 231 DOI: 10.3390/books978-3-03928-119-0 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Plant Sciences
Added to DOAB on : 2020-04-07 23:07:08
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Abstract

The book entitled Medicinal Plants and Natural Product Research describes various aspects of ethnopharmacological uses of medicinal plants; extraction, isolation, and identification of bioactive compounds from medicinal plants; various aspects of biological activity such as antioxidant, antimicrobial, anticancer, immunomodulatory activity, etc., as well as characterization of plant secondary metabolites as active substances from medicinal plants.

Keywords

Chrysanthemum coronarium L. --- aerial parts --- caffeoylquinic acids --- Malian medicinal plants --- Biophytum umbraculum --- Burkea africana --- Lannea velutina --- Terminalia macroptera --- medicinal plants --- traditional knowledge --- Eastern Himalayas --- mountain plants --- ethnobotany --- ethnopharmacology --- bioprospecting --- antibiotic resistance --- antimicrobial --- mechanism of action --- plant metabolite --- saline habitats --- secondary metabolites --- adaptation --- different solvents --- antibiotic resistance --- antimicrobial activity --- cytotoxicity --- ethnobotany --- Eucalyptus --- natural products --- Pseudomonas aeruginosa --- stingless bees --- Tetragonula --- traditional medicine --- basil varieties --- essential oil --- GC-MS --- harvest --- cluster analysis --- antimicrobial --- antioxidants --- medicinal plants --- BHT --- Ficus hirta --- Moraceae --- carboline alkaloids --- sesquiterpenoids --- flavonoids --- antifungal --- phytochemicals --- Nirgundi --- chaste tree --- antibacterial --- free radical --- scavenger --- oxidative stress --- P. alliaceae --- P. niruri --- S. reticulata --- UPLC --- TQ-ESI-MS --- proanthocyanidins --- mass spectrometry --- antioxidant --- cytotoxicity --- Moringa oleifera --- DPPH --- antioxidant activity --- oxidative stress --- sickle cell anemia --- Ophiopogon --- Liriope --- rbcL --- DNA barcoding --- high-resolution melt curve (HRM) analysis --- allergy --- inflammation --- mast cells --- Immulina® --- immunLoges® --- anthracene derivatives --- antimicrobial --- Asphodelus --- ethnomedicine --- skin diseases --- plant-food --- processing --- nutraceuticals --- inflammation --- health --- Arbutus unedo L. --- ?-glucosidase --- catechin --- HPLC --- NMR --- activity --- bioproduct --- Brunfelsia --- Amazonian --- Ecuador --- ethnobotanic --- ayahuasca --- validation --- drug discovery --- scopoletin

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2020 (2)