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Assessment of Energy–Environment–Economy Interrelations

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ISBN: 9783039288090 / 9783039288106 Year: Pages: 274 DOI: 10.3390/books978-3-03928-810-6 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2020-06-09 16:38:57
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Abstract

Energy consumption and economic growth have been of great interest to researchers and policy-makers. Knowing the actual causal relationship between energy and the economy with respect to environmental degradation has important implications for modeling environmental and growth policies. The eleven chapters included herein aim to help researchers, academicians, and especially decision-makers to understand relevant issues and adopt appropriate methods to tackle and solve relevant environmental problems. Various methods from different disciplines are proposed and applied to various environmental and energy issues.

Biomimetic Radical Chemistry and Applications

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ISBN: 9783039283927 9783039283934 Year: Pages: 300 DOI: 10.3390/books978-3-03928-393-4 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology --- Science (General)
Added to DOAB on : 2020-04-07 23:07:09
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Abstract

The enormous importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted a strong interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an important research area. When studying free-radical-based chemical mechanisms, biomimetic chemistry and the design of established biomimetic models come into play to perform experiments in a controlled environment that is suitably designed to be in strict connection with cellular conditions. This Special Issue gives the reader a wide overview of biomimetic radical chemistry, where molecular mechanisms have been defined and molecular libraries of products are developed to also be used as traces for the discovery of some relevant biological processes. Several subjects are presented, with 12 articles and 6 reviews written by specialists in the fields of DNA, proteins, lipids, biotechnological applications, and bioinspired synthesis, having “free radicals” as a common denominator.

Keywords

type 2 diabetes --- glycogen phosphorylase --- anomeric spironucleosides --- 1,6-dioxa-4-azaspiro[4.5]decane --- [1,5]-radical translocation --- DNA --- guanine quadruplexes --- radicals --- electron holes --- oxidative damage --- photo-ionization --- time-resolved spectroscopy --- inhomogeneous reactions --- radiosensitizers --- stationary radiolysis --- pulse radiolysis --- modified nucleosides --- cellular response --- liposomal somatostatin --- retarded delivery --- free radicals --- isomerization --- trans lipid --- peroxidation --- photolysis --- laser flash photolysis --- ?-radiolysis --- singlet oxygen --- nucleosides --- free radicals --- reaction mechanism --- catalase activity --- iron(IV)-oxo --- hydrogen peroxide --- oxidation --- kinetic studies --- gold nanoparticles --- albumin --- EPR spectroscopy --- Raman spectroscopy --- circular dichroism --- beta cells --- diabetes --- confocal microscopy --- lipidomics --- membrane fluidity maps --- cell micropolarity maps --- DNA damage --- 5?,8-cyclopurines --- 8-oxo-dG --- free radicals --- pulse radiolysis --- gamma radiolysis --- Fenton reaction --- oligonucleotides --- oxidative DNA damage --- DNA replication stress --- replication fork stalling --- genomic and epigenomic instability --- DNA methylation --- histone modifications --- miRNAs --- iron porphyrin --- heme --- ATRPase --- iron-mediated ATRP --- bio-mimicking catalyst --- biomimetic radical reaction --- bioinspired chemical catalysis --- protein labeling --- DNA oxidation --- DNA hole transfer --- DNA --- quantum dynamics --- electron transfer --- charge transfer --- radical reaction --- azidoalkylation --- carboazidation --- sulfones --- azides --- Julia–Kocienski olefination --- DNA damage --- copper --- chemical nuclease --- intercalation --- free radical oxidation --- protein stability --- therapeutic proteins --- thiyl radicals --- oxidation --- fragmentation --- cross-link --- 2-thiouracil --- radiosensitizers --- ?OH and ?N3 radicals --- 2c-3e S?S-bonded intermediates --- pulse radiolysis --- TD-DFT methods --- thiobases --- nucleobase derivatives --- reactive aldehydes --- hydroxynonenal --- oxononenal --- free fatty acids --- mitochondrial uncoupling protein --- lipid bilayer membranes

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2020 (2)