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3D printing has revolutionized the microfabrication prototyping workflow over the past few years. With the recent improvements in 3D printing technologies, highly complex microfluidic devices can be fabricated via single-step, rapid, and cost-effective protocols as a promising alternative to the time consuming, costly and sophisticated traditional cleanroom fabrication. Microfluidic devices have enabled a wide range of biochemical and clinical applications, such as cancer screening, micro-physiological system engineering, high-throughput drug testing, and point-of-care diagnostics. Using 3D printing fabrication technologies, alteration of the design features is significantly easier than traditional fabrication, enabling agile iterative design and facilitating rapid prototyping. This can make microfluidic technology more accessible to researchers in various fields and accelerates innovation in the field of microfluidics. Accordingly, this Special Issue seeks to showcase research papers, short communications, and review articles that focus on novel methodological developments in 3D printing and its use for various biochemical and biomedical applications.

3D printing --- Cytotoxicity --- Microfluidics --- Photochemistry --- Polymerization

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"Additive manufacturing or 3D printing, manufacturing a product layer by layer, offers large design freedom and faster product development cycles, as well as low startup cost of production, on-demand production and local production. In principle, any product could be made by additive manufacturing. Even food and living organic cells can be printed. We can create, design and manufacture what we want at the location we want. 3D printing will create a revolution in manufacturing, a real paradigm change.3D printing holds the promise to manufacture with less waste and energy. We can print metals, ceramics, sand, synthetic materials such as plastics, food or living cells. However, the production of plastics is nowadays based on fossil fuels. And that’s where we witness a paradigm change too. The production of these synthetic materials can be based also on biomaterials with biomass as feedstock.A wealth of new and innovative products are emerging when we combine these two paradigm changes: 3D printing and biomaterials. Moreover, the combination of 3D printing with biomaterials holds the promise to realize a truly sustainable and circular economy."

3d printing --- design --- product development --- additive manufacturing --- 0n-demandbiomaterials --- sustainable --- circular economy

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Stimuli-responsive polymer systems can be defined as functional materials that show physical or chemical property changes in response to external stimuli such as temperature, radiation, chemical agents, pH, mechanical stress, and electric and magnetic fields. Recent developments in manufacturing techniques have facilitated the production of a wide range of stimuli-responsive polymer systems, such as micro- and nanoscale structures, with potential applications in soft sensors and actuators, smart textiles, soft robots, and artificial muscles. This book brings together the recent progress in manufacturing techniques, with particular emphasis on 3D and 4D printing and applications of stimuli-responsive polymer systems in biomedicine and soft robotics.

acrylic rubber --- shape-memory polymer --- hindered phenol --- hydrogen bonding --- modeling --- soft actuator --- soft robot --- 3D print --- stimuli-responsive materials --- gelatin --- interpenetrated polymers --- relative humidity --- diffraction gratings --- permeability --- climatic chamber --- silk fibroin --- 3D printing --- bioink --- properties --- biomedical applications --- 4D printing --- shape memory polymer --- self-morphing --- experiments --- FEM --- stimuli-responsive polymer --- soft robotic actuators --- 3D printing --- 4D printing

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3D printing is rapidly emerging as a key manufacturing technique that is capable of serving a wide spectrum of applications, ranging from engineering to biomedical sectors. Its ability to form both simple and intricate shapes through computer-controlled graphics enables it to create a niche in the manufacturing sector. Key challenges remain, and a great deal of research is required to develop 3D printing technology for all classes of materials including polymers, metals, ceramics, and composites. In view of the growing importance of 3D manufacturing worldwide, this Special Issue aims to seek original articles to further assist in the development of this promising technology from both scientific and technological perspectives. Targeted reviews, including mini-reviews, are also welcome, as they play a crucial role in educating students and young researchers.

selective laser melting --- maraging steel --- aging behaviour --- reversed austenite --- 3D printing --- selective laser melting (SLM) --- part redesign --- SLM structure performance --- frame structure reconstruction --- additive manufacturing --- 3D printing --- electron beam melting --- titanium alloys --- microstructure --- wear properties --- selective laser melting --- aluminum matrix composites --- microstructure --- thermodynamic behavior --- formation mechanism --- additive manufacturing --- forming defects --- bonding quality --- forming morphology --- selective laser melting (SLM) --- magnesium --- additive manufacturing --- microstructure --- mechanical properties --- corrosion behavior --- porosity --- microhardness --- Selective Laser Melting (SLM) --- advanced X-ray computed tomography (XCT) --- Ti6Al4V --- selective laser melting --- electron beam melting --- single strut --- mechanical properties --- tailored blanks --- additive manufacturing --- laser deposition welding --- n/a

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Because of the increasing pressure on both food safety and packaging/food waste, the topic is important both for academics, applied research, industry and also for environment protection. Different materials, such as glass, metals, paper and paperboards, and non-degradable and degradable polymers, with versatile properties, are attractive for potential uses in food packaging. Food packaging is the largest area of application within the food sector. Only the nanotechnology-enabled products in the food sector account for ~50% of the market value, with and the annual growth rate is 11.65%. Technological developments are also of great interest. In the food sector, nanotechnology is involved in packaging materials with extremely high gas barriers, antimicrobial properties, and also in nanoencapsulants for the delivery of nutrients, flavors, or aromas, antimicrobial, and antioxidant compounds. Applications of materials, including nanomaterials in packaging and food safety, are in forms of: edible films, polymer nanocomposites, as high barrier packaging materials, nanocoatings, surface biocides, silver nanoparticles as potent antimicrobial agents, nutrition and neutraceuticals, active/bioactive packaging, intelligent packaging, nanosensors and nanomaterial-based assays for the detection of food relevant analytes (gasses, small organic molecules and food-borne pathogens) and bioplastics.

powdered rosemary ethanolic extract --- poly(lactic acid) --- bioactive food packaging --- biomaterials --- polymer --- nanocomposites --- nanocoatings --- food packaging --- risks --- smart nanomaterials --- electrospinning --- nanocoating --- chitosan --- vegetable oil --- essential oil --- cold-press oil --- antimicrobial --- antioxidant --- edible film --- alginate film --- pectin film --- essential oil --- barrier properties --- mechanical properties --- graphene --- carbon nanotubes --- poly(lactic) acid --- degradation --- combustion --- fire --- risk analysis --- chitosan --- rosehip seed oil --- montmorillonite nanoclay --- antibacterial --- antioxidant --- food packaging --- customization --- product design --- personalized design --- reverse engineering --- computer aid design (CAD) --- fused deposition modelling (FDM) --- packaging design --- product design --- mechanical properties --- thermoforming --- tensile test --- 3D printing --- simulation --- technology --- thiazolidine-4-one scaffold --- chitosan --- polymeric systems --- antibacterial activity