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Micro-, Meso- and Macro-Dynamics of the Brain

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Book Series: Research and Perspectives in Neurosciences ISSN: 0945-6082 ISBN: 9783319288017 9783319288024 Year: Pages: 172 DOI: 10.1007/978-3-319-28802-4 Language: English
Publisher: Springer
Subject: Neurology
Added to DOAB on : 2016-12-20 11:07:42
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This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The individual chapters cover several fascinating facets of contemporary neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Each of these topics require appropriate levels of analyses with sufficiently high temporal and spatial resolution of neuronal activity in both local and global networks, supplemented by models and theories to explain how different levels of brain dynamics interact with each other and how the failure of such interactions results in neurologic and mental disease. While such complex questions cannot be answered exhaustively by a dozen or so chapters, this volume offers a nice synthesis of current thinking and work-in-progress on micro-, meso- and macro- dynamics of the brain.

Stem Cells in Neuroendocrinology

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Book Series: Research and Perspectives in Endocrine Interactions ISSN: 1861-2253 ISBN: 9783319416021 9783319416038 Year: Pages: 156 DOI: 10.1007/978-3-319-41603-8 Language: English
Publisher: Springer
Subject: Internal medicine
Added to DOAB on : 2016-12-20 11:36:46
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This volume starts with an elementary introduction covering stem cell methodologies used to produce specific types of neurons, possibilities for their therapeutic use, and warnings of technical problems. In addition the authors report successes in achieving the derivation of a specific type of neuron. The dopamine neuron offers an important example and is discussed in more detail. Additional chapters cover problems obviously approachable with cells derived from stem cells, including their need in surgeries for pituitary cancers. The last chapter provides an overview of this particular field of research and presents a vision for its future directions.

A Time for Metabolism and Hormones

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Book Series: Research and Perspectives in Endocrine Interactions ISSN: 1861-2253 ISBN: 9783319270685 9783319270692 Year: Pages: 132 DOI: 10.1007/978-3-319-27069-2 Language: English
Publisher: Springer
Subject: Internal medicine
Added to DOAB on : 2016-12-20 11:46:51
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Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.

Micro-, Meso- and Macro-Connectomics of the Brain

Authors: --- ---
Book Series: Research and Perspectives in Neurosciences ISSN: 0945-6082 ISBN: 9783319277769 9783319277776 Year: Pages: 166 DOI: 10.1007/978-3-319-27777-6 Language: English
Publisher: Springer
Subject: Neurology
Added to DOAB on : 2016-12-20 11:23:03
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This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.

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