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Vitamin E in Health and Disease

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ISBN: 9781789842456 9781789842463 Year: Pages: 110 DOI: 10.5772/intechopen.74469 Language: English
Publisher: IntechOpen
Subject: Nutrition and Food Sciences
Added to DOAB on : 2019-10-03 07:51:52

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In this book, Vitamin E in Health and Disease, the chapter by Dr Lisa Schmölz et al., The Hepatic Fate of Vitamin E, includes the hepatic metabolism of vitamin E, its storage, release, distribution, and its effects on the metabolism in great detail, as well as its effect on the prevention of diseases, in addition to its role in anti-aging. The chapter by Dr Rusu Anca Elena reports on the effect of vitamin E in patients with hemodialysis. In a similar manner, the chapter of Drs Rayan Ahmed and Paul W. Sylvester describe g-Tocotrienol, a natural isoform within the vitamin E family of compounds, which displays potent antiproliferative, apoptotic and reversal of epithelial-to-mesenchymal-transition activity against breast cancer, employing treatment doses that have little or no effect on normal cell viability. The chapter by Milka Mileva and Angel S. Galabov describes how vitamin E could be recommended as a reliable agent, indeed as a component in multiorgan flu therapy. Last, Dr Juan José Godina-Nava et al. describe the cytoprotector effect of the 120-Hz electromagnetic fields in early hepatocarcinogenesis.

Reflections on Bioethics

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ISBN: 9781789232189 9781789232196 Year: Pages: 198 DOI: 10.5772/intechopen.71309 Language: English
Publisher: IntechOpen
Subject: Philosophy
Added to DOAB on : 2019-10-03 07:51:51

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The book Reflections on Bioethics is an effort that brings together works grouped into five sections: ""Bioethics and Health"", ""Bioethics and Education"", ""Bioethics and Technology"", ""Bioethics in the Use of Experimental Animals"",and ""Selected Topics of Bioethics"". In each of these sections, the fundamental concepts of bioethics and their relationship with each of these branches of knowledge are covered. The purpose is to give the reader a specific document of topics, it is not intended to be a treaty because the study of any of the five sections is very broad. However, this is an effort that manages to combine in interdisciplinary subjects that are fundamental for professionals of all fields of knowledge.

A Master Regulator of Oxidative Stress - The Transcription Factor Nrf2

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ISBN: 9789535128373 9789535128380 Year: Pages: 210 DOI: 10.5772/62743 Language: English
Publisher: IntechOpen
Subject: Biology
Added to DOAB on : 2019-10-03 07:51:49

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Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. Therefore, the efforts of various investigation groups are centered on finding activators and/or inhibitors of Nrf-2 to prevent or control diverse diseases, for example, cancer, where it would be important to regulate Nrf-2 in order for it to activate apoptosis pathways in cancerogenous cells, or in neurodegenerative diseases where cell death is predominant, it would be important for Nrf-2 to activate antiapoptotic pathways.

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