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Bone Marrow T Cells at the Center Stage in Immunological Memory

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889450930 Year: Pages: 84 DOI: 10.3389/978-2-88945-093-0 Language: English
Publisher: Frontiers Media SA
Subject: Allergy and Immunology --- Medicine (General)
Added to DOAB on : 2017-07-06 13:27:36
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Abstract

Increasing evidence supports the notion that bone marrow (BM) represents a relevant player in T cell responses, particularly in its role as a specialized organ for long-term memory. Memory T cells are enriched in the BM over long times after priming, and can be recruited to the periphery upon antigenic challenge. The articles in this research topic include discussions of whether these T cells are passing-through or truly resident, as well as a debate on the extent of proliferation of BM memory T cells. Original research articles in this collection include an analysis of the number of memory T cells found in different bones as well as effects of B cell depletion on T cell memory in the BM. T cells in the BM can influence a number of processes, from bone remodeling, control of cancer, to effects on hemopoiesis or Graft versus Host Disease (GVHD). This research topic contains several contributions to these topics including discussions on how to translate BM T cell knowledge into medicine.

Proceedings of ICI Milan 2013

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889193387 Year: Pages: 196 DOI: 10.3389/978-2-88919-338-7 Language: English
Publisher: Frontiers Media SA
Subject: Allergy and Immunology --- Medicine (General)
Added to DOAB on : 2016-03-10 08:14:32
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Abstract

This Research Topic covers all of the major lectures and symposia addresses delivered by invited speakers at the 2013 International Congress in Immunology (ICI) at Milan, Italy, August 22-27, 2013.

Keywords

ICI2013 --- immunology --- IUIS --- Milan --- SIICA

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