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Molecular Advances in Wheat and Barley

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ISBN: 9783039213719 9783039213726 Year: Pages: 290 DOI: 10.3390/books978-3-03921-372-6 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology
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Allohexaploid bread wheat and diploid barley are two of the most cultivated crops in the world. This book reports novel research and reviews concerning the use of modern technologies to understand the molecular bases for wheat and barley improvement. The contributions published in this book illustrate research advances in wheat and barley knowledge using modern molecular techniques. These molecular approaches cover genomic, transcriptomic, proteomic, and phenomic levels, together with new tools for gene identification and the development of novel molecular markers. Overall, the contributions for this book lead to a further understanding of regulatory systems in order to improve wheat and barley performance.

Keywords

Triticum durum --- Aegilops tauschii --- Triticum aestivum --- marker-trait associations --- genes --- bread wheat --- genetic biofortification --- favorable alleles --- allohexaploid --- homoeolog --- hybrid necrosis --- molecular marker --- wheat --- wheat --- rye --- 6R --- small segment translocation --- powdery mildew --- transgenic wheat --- 12-oxophytodienoate reductase --- jasmonates --- freezing tolerance --- HIGS --- transgene --- wheat --- barley --- cereal cyst nematodes --- wheat --- barely --- breeding --- biotechnology --- resistance --- Triticum aestivum --- Landrace --- Powdery mildew --- Bulked segregant analysis-RNA-Seq (BSR-Seq) --- Single nucleotide polymorphism (SNP) --- Kompetitive Allele Specific PCR (KASP) --- Blumeria graminis f. sp. tritici --- protein two-dimensional electrophoresis --- mass spectrometry --- Pm40 --- Barley --- Grain development --- Transcriptional dynamics --- RNA editing --- RNA-seq --- durum wheat --- Tunisian landraces --- center of diversity --- genetic diversity --- population structure --- DArTseq technology --- chromatin --- 3D-FISH --- nucleus --- introgression --- rye --- hybrid --- wheat --- genome stability --- wheat --- Thinopyrum --- chromosome --- ND-FISH --- oligo probe --- barley --- wheat --- protease --- germination --- grain --- abiotic stress --- antioxidant enzymes --- aquaporin --- TdPIP2 --- 1 --- histochemical analysis --- transgenic wheat --- transpiration --- wheat --- Aegilops tauschii --- Lr42 --- disease resistance --- molecular mapping --- KASP markers --- marker-assisted selection --- phytase --- wheat --- barley --- purple acid phosphatase phytase --- PAPhy --- mature grain phytase activity (MGPA) --- genome assembly --- bread wheat --- barley --- optical mapping --- BAC --- ribosomal DNA --- cereals --- CRISPR --- crops --- genetic engineering --- genome editing --- plant --- Triticeae --- n/a

Radiation Tolerant Electronics

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ISBN: 9783039212798 9783039212804 Year: Pages: 210 DOI: 10.3390/books978-3-03921-280-4 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering --- Electrical and Nuclear Engineering
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Research on radiation-tolerant electronics has increased rapidly over the past few years, resulting in many interesting approaches to modeling radiation effects and designing radiation-hardened integrated circuits and embedded systems. This research is strongly driven by the growing need for radiation-hardened electronics for space applications, high-energy physics experiments such as those on the Large Hadron Collider at CERN, and many terrestrial nuclear applications including nuclear energy and nuclear safety. With the progressive scaling of integrated circuit technologies and the growing complexity of electronic systems, their susceptibility to ionizing radiation has raised many exciting challenges, which are expected to drive research in the coming decade. In this book we highlight recent breakthroughs in the study of radiation effects in advanced semiconductor devices, as well as in high-performance analog, mixed signal, RF, and digital integrated circuits. We also focus on advances in embedded radiation hardening in both FPGA and microcontroller systems and apply radiation-hardened embedded systems for cryptography and image processing, targeting space applications.

Keywords

physical unclonable function --- FPGA --- total ionizing dose --- Co-60 gamma radiation --- ring-oscillator --- Image processing --- line buffer --- SRAM-based FPGA --- single event upset (SEU) --- configuration memory --- soft error --- radiation-hardened --- instrumentation amplifier --- sensor readout IC --- total ionizing dose --- nuclear fusion --- radiation hardening --- hardening by design --- TMR --- selective hardening --- VHDL --- FPGA --- radiation hardening --- single event upsets --- heavy ions --- error rates --- single-event upsets (SEUs) --- digital integrated circuits --- triple modular redundancy (TMR) --- radiation hardening by design --- TMR --- FMR --- 4MR --- triplex–duplex --- FPGA-based digital controller --- radiation tolerant --- single event effects --- proton irradiation --- RFIC --- SEE testing --- space application --- CMOS --- TDC --- radiation effects --- total ionizing dose (TID) --- single-shot --- PLL --- ring oscillator --- analog single-event transient (ASET) --- bandgap voltage reference (BGR) --- CMOS analog integrated circuits --- gamma-rays --- heavy-ions --- ionization --- protons --- radiation hardening by design (RHBD) --- reference circuits --- single-event effects (SEE) --- space electronics --- total ionization dose (TID) --- voltage reference --- X-rays --- radiation-hardened --- single event gate rupture (SEGR) --- SEB --- power MOSFETs --- Single-Event Upsets (SEUs) --- radiation effects --- Ring Oscillators --- Impulse Sensitive Function --- Radiation Hardening by Design --- fault tolerance --- single event upset --- proton irradiation effects --- neutron irradiation effects --- soft errors --- saturation effect --- gain degradation --- total ionizing dose --- gamma ray --- bipolar transistor --- single event transient (SET) --- single event opset (SEU) --- radiation-hardening-by-design (RHBD) --- frequency synthesizers --- voltage controlled oscillator (VCO) --- frequency divider by two --- CMOS --- n/a

Physiological Responses to Abiotic and Biotic Stress in Forest Trees

Authors: ---
ISBN: 9783039215140 9783039215157 Year: Pages: 294 DOI: 10.3390/books978-3-03921-515-7 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering --- Environmental Engineering
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As sessile organisms, plants have to cope with a multitude of natural and anthropogenic forms of stress in their environment. Due to their longevity, this is of particular significance for trees. As a consequence, trees develop an orchestra of resilience and resistance mechanisms to biotic and abiotic stresses in order to support their growth and development in a constantly changing atmospheric and pedospheric environment. The objective of this Special Issue of Forests is to summarize state-of-art knowledge and report the current progress on the processes that determine the resilience and resistance of trees from different zonobiomes as well as all forms of biotic and abiotic stress from the molecular to the whole tree level.

Keywords

drought --- mid-term --- non-structural carbohydrate --- soluble sugar --- starch --- Pinus massoniana --- salinity --- Carpinus betulus --- morphological indices --- gas exchange --- osmotic adjustment substances --- antioxidant enzyme activity --- ion relationships --- Populus simonii Carr. (poplar) --- intrinsic water-use efficiency --- tree rings --- basal area increment --- long-term drought --- hydrophilic polymers --- Stockosorb --- Luquasorb --- Konjac glucomannan --- photosynthesis --- ion relation --- Fagus sylvatica L. --- Abies alba Mill. --- N nutrition --- mixed stands --- pure stands --- soil N --- water relations --- 24-epiBL application --- salt stress --- ion contents --- chloroplast ultrastructure --- photosynthesis --- Robinia pseudoacacia L. --- elevation gradient --- forest type --- growth --- leaf properties --- Pinus koraiensis Sieb. et Zucc. --- Heterobasidion parviporum --- Heterobasidion annosum --- Norway spruce --- disturbance --- water availability --- pathogen --- infection --- Carpinus turczaninowii --- salinity treatments --- ecophysiology --- photosynthetic responses --- organic osmolytes --- ion homeostasis --- antioxidant enzymes --- glutaredoxin --- subcellular localization --- expression --- tapping panel dryness --- defense response --- rubber tree --- Ca2+ signal --- drought stress --- living cell --- Moso Bamboo (Phyllostachys edulis) --- plasma membrane Ca2+ channels --- signal network --- Aleppo pine --- Greece --- photosynthesis --- water potential --- ?13C --- sap flow --- canopy conductance --- climate --- molecular cloning --- functional analysis --- TCP --- DELLA --- GA-signaling pathway --- Fraxinus mandshurica Rupr. --- wood formation --- abiotic stress --- nutrition --- gene regulation --- tree --- bamboo forest --- cold stress --- physiological response --- silicon fertilization --- plant tolerance --- reactive oxygen species --- antioxidant activity --- proline --- Populus euphratica --- salt stress --- salicylic acid --- malondialdehyde --- differentially expressed genes --- n/a

Protective and Detrimental Role of Heme Oxygenase-1

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ISBN: 9783039218066 9783039218073 Year: Pages: 220 DOI: 10.3390/books978-3-03921-807-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2019-12-09 11:49:16
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The book “Protective and Detrimental Role of Heme Oxygenase-1”, includes a selection of original research papers and reviews aimed at understanding the dual role (protective and detrimental) of HO-1 and the involved signaling pathways. Original research papers and reviews aimed at the identification of natural molecules or new synthetic compounds able to modulate HO-1 activity/expression help make HO-1 a potential therapeutic target for the amelioration of various diseases.

Keywords

ferroptosis --- heme oxygenase-1 --- iron --- reactive oxygen species --- glutathione --- chemotherapy --- paracetamol --- Myristica fragrans kernels --- heme oxygenase 1 --- liver --- glucocorticoid receptor --- GR --- heme oxygenase 1 --- HO-1 --- prostate cancer --- ANTIGEN presenting cell --- tolerance --- Tet-ON system --- antigen presentation --- analgesia --- carbon monoxide --- heme oxygenase 1 --- inflammatory pain --- locus coeruleus --- nitric oxide --- bilirubin --- Gunn rats --- hyperbilirubinemia --- inflammation --- LPS --- NF-?B --- caloric restriction --- Sirtuin 1 --- Heme Oxygenase-1 --- PGC-1? --- cardiomyopathy --- diabetes mellitus --- Type 1 diabetes mellitus (T1D) --- Pancreatic oxidative damage --- Heme oxygenase-1 (HO-1) inducers --- Caffeic acid phenethyl ester (CAPE) --- Reactive oxygen species (ROS) --- Dimethylarginine dimethylaminohydrolase-1 (DDAH-1) --- Inducible nitric oxide synthase (iNOS) --- Gamma-Glutamyl-Cysteine Ligase (GGCL) --- prostate cancer --- heme oxygenase --- metformin --- apoptosis --- ER stress --- HO-1 activity inhibitor --- carbon monoxide --- lung preservation --- ischemia–reperfusion injury --- high-pressure gas --- Colon cancer --- Betula etnensis Raf. --- oxidative stress --- heme oxigenase-1 --- ferroptosis --- thiol groups --- angiotensin II --- mineralocorticoid receptor --- heme oxygenase 1 --- sirtuin 1 --- adipocytes --- oxidative stress --- heme oxygenase-1 --- atherosclerosis --- coronary artery disease --- peripheral artery disease --- carotid plaque --- heme oxygenase --- endoplasmic reticulum stress --- hemoglobin --- heme --- n/a

There is a Crack in Everything—Education and Religion in a Secular Age

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ISBN: 9783039212774 9783039212781 Year: Pages: 266 DOI: 10.3390/books978-3-03921-278-1 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Religion
Added to DOAB on : 2019-12-09 16:39:37
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There are two constants in academic and theological discourse throughout history, they are the debate around secularization and the dialogue concerning the intersection of religion and education. Each age has had its debate about modernizing forces that drive concerns of impending secularization. In this publication this theme is approached from perspectives of teachers, of students, of policy makers and situated in a politico-historical context. Aware of the fact that in today’s plural societies one sacred canopy is non-existent anymore, cracks of the sacred canopy/canopies are described, as well as ‘the light that gets in’, the possible and challenging ways out are roughly sketched. We expect that each of the contributions of scholars of the East and the West, of the North and the South, and their presented examples and case studies, will stimulate the ongoing exploration and elaboration on the relationship between education and religion in todays’ and the coming world – work-in-progress for coming generations.

Keywords

religious education --- secularization --- pluralism --- non-confessional --- classroom observation --- ethnography --- Christian --- university --- radicalization --- post-secular --- secular --- religion education --- secularity --- secularism --- religion in public life --- representation of religion --- Bible --- Qur’an --- Ubuntu --- orthodoxy --- orthokardia --- orthopraxis --- Weltanschauung --- inter-worldview education --- Europe --- tolerance --- inequality --- power --- state Jewish religious education --- state Jewish secular education --- state Arab Moslem education --- state Christian education --- state Druze education --- religious and heritage education --- citizenship education --- religious minorities --- secularism --- Muslim --- youth --- immigration --- social boundaries --- identification --- college --- Québec --- inclusion --- worldview education --- universal design for learning --- learning in the presence of the other --- reflexive inclusion --- secularization --- rationality --- medicine --- theology --- symbiotic relevance --- school identity --- secularization --- secondary education --- teachers --- worldviews --- morality --- spirituality --- religion --- religious education --- life-as --- subjective-life --- secularism --- religious education --- values education --- strong religious schools --- Dutch Bible Belt --- citizenship education --- religious education --- liberal society --- secularization --- symbolic language --- philosophy of life --- religious sources of meaning --- metaphoric sensitivity --- inventive imagination --- role playing/bibliodrama --- identity construction --- life orientation --- bibliodrama --- narratives --- interreligious encounters --- education --- image of imams --- secularization --- plurality --- spiritual religiosity --- popular religiosity --- radicalization --- n/a --- n/a

Cow's Milk and Allergy

Authors: ---
ISBN: 9783039280285 9783039280292 Year: Pages: 232 DOI: 10.3390/books978-3-03928-029-2 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Nutrition and Food Sciences --- Biology --- Science (General)
Added to DOAB on : 2020-01-30 16:39:46
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The purpose of this Special Issue “Cow’s Milk and Allergy” is to provide an overview of the association of cow’s milk with allergy. This topic has two quite different faces. On the one hand, we are all aware of the importance of cow’s milk allergy in early life. What is less known is that the consumption of raw, unprocessed milk is associated with a lower incidence of asthma and rhinitis. This Special Issue takes a closer look at all of these aspects of cow’s milk and allergy and focus on the following questions:

Keywords

allergic march --- cow’s milk allergy --- genome-wide association --- polygenic risk score --- food allergy --- cow’s milk --- camel milk --- infant formula --- animal models --- raw milk --- allergy --- asthma --- protection --- cow’s milk allergy --- casein --- cell-mediated reactions --- delayed-type hypersensitivity --- extracellular vesicles --- miRNA-150 --- cow’s milk allergy --- epidemiology --- natural history --- prevalence --- Cow’s milk allergy (CMA), anaphylaxis --- sensitization pattern --- cow’s milk allergens --- CAP-FEIA (Fluorescence Enzyme Immunoassay) --- multiplex dot test --- basophil activation test (BAT), human breast milk --- cow’s milk allergy --- immune system --- dietary intervention --- bioactive peptides --- gut microbiota --- prebiotics --- probiotics --- aggregation --- allergenicity --- ?-lactoglobulin --- CML --- glycation --- sRAGE --- IgE binding --- partial hydrolysate --- cow’s milk protein allergy --- hydrolysate --- infant feeding --- Middle-East --- step-down --- infant allergy --- cow’s milk allergy --- cow’s milk allergens --- diagnosis of cow’s milk allergy --- molecular diagnosis --- treatment of cow’s milk allergy --- prevention of cow’s milk allergy --- alkaline phosphatase --- allergic diseases --- food allergy --- immune regulation --- milk processing --- raw cow’s milk --- milk allergen --- baked milk --- cow’s milk --- allergenicity modulation --- proteomics --- epigenetics --- farming effect --- food allergy --- histone acetylation --- milk processing --- raw milk --- cow’s milk allergy --- milk --- hydrolysate --- asthma --- processing --- tolerance --- allergy --- cow’s milk --- formula --- therapy --- immune cells --- Immunoglubuline E

Protection Strategy against Spruce Budworm

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ISBN: 9783039280964 9783039280971 Year: Pages: 220 DOI: 10.3390/books978-3-03928-097-1 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Forestry --- Biology --- Science (General)
Added to DOAB on : 2020-01-30 16:39:46
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Spruce budworm (Choristoneura fumiferana (Clem.)) outbreaks are a dominant natural disturbance in the forests of Canada and northeastern USA. Widespread, severe defoliation by this native insect results in large-scale mortality and growth reductions of spruce (Picea sp.) and balsam fir (Abies balsamea (L.) Mill.) forests, and largely determines future age–class structure and productivity. The last major spruce budworm outbreak defoliated over 58 million hectares in the 1970s–1980s, and caused 32–43 million m3/year of timber volume losses from 1978 to 1987, in Canada. Management to deal with spruce budworm outbreaks has emphasized forest protection, spraying registered insecticides to prevent defoliation and keep trees alive. Other tactics can include salvage harvesting, altering harvest schedules to remove the most susceptible stands, or reducing future susceptibility by planting or thinning. Chemical insecticides are no longer used, and protection strategies use biological insecticides Bacillus thuringiensis (B.t.) or tebufenozide, a specific insect growth regulator. Over the last five years, a $30 million research project has tested another possible management tactic, termed an ‘early intervention strategy’, aimed at area-wide management of spruce budworm populations. This includes intensive monitoring to detect ‘hot spots’ of rising budworm populations before defoliation occurs, targeted insecticide treatment to prevent spread, and detailed research into target and non-target insect effects. The objective of this Special Issue is to compile the most recent research on protection strategies against spruce budworm. A series of papers will describe results and prospects for the use of an early intervention strategy in spruce budworm and other insect management.

Keywords

forest pests --- defoliation --- spruce budworm --- multi-spectral remote sensing --- Acadian region --- Maine --- Quebec --- Choristoneura fumiferana --- Abies balsamea --- hardwood content --- defoliation prediction --- Choristoneura fumiferana --- annual defoliation --- spatial autocorrelation --- spatial-temporal patterns --- mixed effect models --- intertree variance --- insect population management --- spruce budworm --- early intervention --- defoliation --- economic losses --- decision support system --- optimized treatment design --- insect population management --- spruce budworm --- early intervention --- defoliation --- economic losses --- decision support system --- computable general equilibrium model --- Pinaceae --- endophytic fungi --- plant tolerance --- Phialocephala scopiformis --- Picea glauca --- spruce budworm --- phenology --- insect susceptibility --- spruce budworm --- forest protection --- early intervention strategy --- egg recruitment --- apparent fecundity --- growth rate --- spruce budworm --- Choristoneura fumiferana --- forest protection --- early intervention strategy --- survival --- apparent fecundity --- immigration --- growth rate --- treatment threshold --- insecticides --- spruce budworm --- moth --- tortricidae --- Choristoneura fumiferana (Clemens) --- forest protection --- early intervention strategy --- pheromone mating disruption --- migration --- dispersal --- spruce budworm --- Choristoneura fumiferana --- moth --- Lepidoptera --- forest protection --- early intervention strategy --- migration --- simulation --- aerobiology --- moths --- migration --- forest protection --- spruce budworm --- Choristoneura fumiferana (Clem.) --- early intervention strategy --- modelling --- circadian rhythm --- foliage protection --- population control --- monitoring --- area-wide management --- science communication --- economic and ecological cost: benefit analyses --- early intervention strategy --- foliage protection --- defoliation --- monitoring --- insecticide application

Lipopolysaccharides (LPSs)

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ISBN: 9783039282562 9783039282579 Year: Pages: 390 DOI: 10.3390/books978-3-03928-257-9 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Allergy and Immunology
Added to DOAB on : 2020-04-07 23:07:08
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The cytoplasm of Gram-negative bacteria is bound by three layers: an inner membrane, a layer of peptidoglycan, and an outer membrane. The outer membrane is an asymmetric lipidic bilayer, with phospholipids on its inner surface and lipopolysaccharides (LPSs) on the outside, with the latter being the major component of the outer leaflet and covering nearly three-quarters of the total outer cell surface. All LPSs possess the same general chemical architecture independently of bacterial activity (pathogenic, symbiotic, commensal), ecological niche (human, animal, soil, plant, water), or growth conditions. Endotoxins are large amphiphilic molecules consisting of a hydrophilic polysaccharide component and a covalently bound hydrophobic and highly conserved lipid component, termed lipid A (the endotoxin subunit). The polysaccharide component can be divided into two subdomains: the internal and conserved core region as well as the more external and highly variable O-specific chain, also referred to as the O-antigen due to its immunogenic properties. LPSs are endotoxins, one of the most potent class of activators of the mammalian immune system; they can be released from cell surfaces of bacteria during multiplication, lysis, and death. LPS can act through its biological center (lipid A component) on various cell types, of which macrophages and monocytes are the most important.

Keywords

aspirin --- hepcidin --- P65 (nuclear factor-?B) --- IL-6/JAK2/STAT3 pathway --- lipopolysaccharide (LPS) --- nitric oxide (NO) --- iron regulatory protein 1 (IRP1) --- Megalobrama amblycephala --- lipopolysaccharide induced TNF? factor --- lipopolysaccharide stimulation --- innate immune --- Aeromonas --- genomics --- inner core oligosaccharide --- outer core oligosaccharide --- lipopolysaccharide --- lipopolysaccharide --- Erwinia amylovora --- NMR --- ESI FT-ICR --- structural determination --- Bordetellae --- Bordetella holmesii --- endotoxin --- lipid A --- structure --- mass spectrometry --- genomic --- Edwardsiella tarda --- core oligosaccharide --- MALDI-TOF MS --- ESI MSn --- NMR --- genomic --- LPS tolerance --- hypothalamic inflammation --- insulin resistance --- pJNK --- fibroblast --- keratocyte --- cornea --- lipopolysaccharide --- bacteria --- chemokine --- adhesion molecule --- collagen --- tear fluid --- serum resistance --- complement --- Salmonella --- lipopolysaccharide --- sialic acid --- reptile-associated salmonellosis --- sepsis --- time response --- inflammation --- oxidative stress --- endotoxaemia --- mouse --- rat --- lipopolysaccharide --- double-stranded RNA --- epithelial cell --- dendritic cell --- allergic respiratory disorder --- hygiene hypothesis --- rhinovirus --- respiratory syncytial virus --- toll-like receptor --- LPS --- lipopolysaccharide --- heptosyltransferase --- protein dynamics --- glycosyltransferase --- GT-B --- inhibitor design --- lipopolysaccharide --- Coxiella burnetii --- Q fever --- phagosome --- virenose --- Plesiomonas shigelloides --- O-antigen --- lipopolysaccharide --- O-acetylation --- d-galactan I --- HR-MAS --- NMR spectroscopy --- endotoxin --- lipopolysaccharide --- Low Endotoxin Recovery --- phase transitions --- polysorbate --- LPS aggregates --- Small Angle X-ray Scattering --- MAT --- LAL and LER --- anti-conjugate serum --- core oligosaccharide --- lipopolysaccharide --- NMR spectroscopy --- ESI MS --- Proteus penneri

Diet and Immune Function

Authors: --- ---
ISBN: 9783039216123 / 9783039216130 Year: Pages: 314 DOI: 10.3390/books978-3-03921-613-0 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Allergy and Immunology
Added to DOAB on : 2020-06-09 16:38:57
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Supporting initiation, development and resolution of appropriate immune responses is key to survival. Many nutrients and dietary components have been purported to have a role in supporting optimal immune function. This is vital throughout the life course, from the development and programming of the immune system in early life, to supporting immunity and reducing chronic inflammation in older people. In this special issue of Nutrients, we examine the evidence for the role of diet and dietary components in promoting protective immunity.

Keywords

inflammation --- toll-like receptor 4 --- obesity --- fatty acids --- protein hydrolysate --- bioactive peptide --- immunomodulation --- Toll-like receptor --- functional foods --- zinc --- sepsis --- biomarker --- supplementation --- homeostasis --- human milk oligosaccharides --- intestinal immune system --- microbiota --- fermented milk --- Th1/Th17 response --- inflammatory process --- growth factors --- breast milk --- immunonutrition --- cytokines --- lymphocytes --- selenocysteine --- macrophage --- T cell --- antibody --- inflammation --- cancer --- adults --- age-related immunity --- deficiency --- elderly --- immunosenescence --- infants --- infection --- micronutrients --- older people --- nutrition --- amino acids --- leukocytes --- skeletal muscle --- gut --- liver --- anorexia nervosa --- inflammatory markers --- inflammation --- cytokines --- chemokines --- adhesion molecules --- carbohydrates --- fiber --- food structure --- formulation --- plant --- microbiota --- inflammation --- metabolism --- nutrition guidelines --- vitamin E --- macrophages --- T cells --- dendritic cells --- immunomodulation --- infection --- polyphenols --- immune system --- inflammation --- molecular mechanisms --- nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) --- arachidonic acid --- mitogen-activated protein Kinase (MAPK) --- cytokines --- oxidative stress --- reactive oxygen species (ROS) --- cyclooxygenase (COX) --- nitric oxide synthase (NOS) --- lipoxygenase (LOX) --- superoxide dismutase (SOD) --- inhibitor of kappa kinase (IKK) --- extra-cellular signal regulated kinases (ERK) --- cancer --- anti-inflammation --- anti-tumorigenic --- chronic inflammatory conditions --- macrophages --- T helper 1 (Th1) --- Th17 --- Treg --- vitamin D --- immune system --- gut microbiota --- autoimmune diseases --- T cells --- weaning --- oligosaccharides --- non-digestible carbohydrates --- metabolites --- gut barrier --- tolerance --- nutrition --- immunity --- macronutrients --- micronutrients --- microbiome --- life course --- probiotic --- prebiotic --- inflammation

Extraintestinal Manifestations of Coeliac Disease

Authors: ---
ISBN: 9783038977988 9783038977995 Year: Pages: 270 DOI: 10.3390/books978-3-03897-799-5 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Nutrition and Food Sciences
Added to DOAB on : 2019-04-25 16:37:17
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Coeliac Disease (CD) affects at least 1% of the population. &ldquo;Classical&rdquo; CD refers to gastrointestinal presentations with anaemia and gastrointestinal symptoms. CD can, however, present with extraintestinal manifestations, the commonest of which are dermatitis herpetiformis and neurological presentations (e.g., ataxia, neuropathy, encephalopathy). Recognition and research into the pathophysiology of such manifestations is likely to enhance our understanding of this complex autoimmune disorder.

Keywords

dermatitis herpetiformis --- coeliac disease --- fracture --- bone health --- quality of life --- Gilles de la Tourette syndrome (GTS) --- children and adults --- motor and vocal/phonic tics --- obsessive-compulsive disorder (OCD) --- non-coeliac gluten sensitivity (NCGS) --- gluten-free diet --- one-year adherence --- dermatitis herpetiformis --- coeliac disease --- prevalence --- epidermal transglutaminase --- gluten-free diet --- long-term prognosis --- dermatitis herpetiformis --- coeliac disease --- gluten-free diet --- small bowel --- villous atrophy --- prognosis --- gluten neuropathy --- coeliac disease --- gluten free diet --- quality of life --- male --- extra-intestinal --- gastrointestinal --- celiac disease --- celiac disease --- dermatitis herpetiformis --- urticaria --- atopic dermatitis --- psoriasis --- recurrent aphtous ulceration --- rosacea --- alopecia areata --- cutaneous vasculitis --- gluten-free diet --- celiac disease --- glandular autoimmunity --- autoimmune thyroid disease --- type 1 diabetes --- polyglandular autoimmune syndrome --- coeliac disease --- osteoporosis --- fractures --- celiac disease --- non-celiac gluten sensitivity --- psychiatric disorders --- depression --- anxiety disorders --- eating disorders --- ADHD --- autism --- psychosis --- autoimmunity --- celiac hepatitis --- gut–liver axis --- liver immunity --- non-alcoholic fatty liver disease --- tolerance --- intestinal barrier --- celiac disease --- extraintestinal --- recognition --- diagnosis --- clinical presentation --- gluten-free diet --- prognosis --- movement disorders --- coeliac disease --- gluten --- gluten free diet --- celiac disease --- gluten --- gliadin --- autoantibody --- B cell --- T cell --- transglutaminase --- synapsin --- ganglioside --- gluten sensitivity --- gastrointestinal symptoms --- molecular mimicry --- intermolecular help --- biomarker --- autoimmune pancreatitis --- coeliac disease --- pancreatic disorders --- screening --- Gluten ataxia --- antigliadin antibodies --- coeliac disease --- MR spectroscopy --- gluten sensitive enteropathy --- antigliadin antibody titre --- gluten sensitivity --- coeliac disease --- gluten free diet --- migraine --- headache --- fatigue --- energy --- celiac disease --- extra-intestinal manifestations --- gluten --- latent celiac disease --- potential celiac disease --- extra-intestinal manifestations --- mild enteropathy --- early developing celiac disease --- genetic gluten intolerance --- natural history --- celiac trait --- celiac disease --- gluten neuropathy --- gluten ataxia --- prevalence --- incidence --- gluten-free diet

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