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Muscle Cell and Tissue

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Book Series: 2015-09-02 ISBN: 9789535121565 9789535142188 Year: Pages: 486 DOI: 10.5772/59347 Language: English
Publisher: IntechOpen
Subject: Medicine (General)
Added to DOAB on : 2019-10-03 07:51:49

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In order to complete tissue regeneration, various cells such as neuronal, skeletal, smooth, endothelial, and immune (e.g., macrophage) interact smoothly with each other. This book, Muscle Cells and Tissues, offers a wide range of topics such as stem cells, cell culture, biomaterials, epigenetics, therapeutics, and the creation of tissues and organs. Novel applications for cell and tissue engineering including cell therapy, tissue models, and disease pathology modeling are discussed. The book also deals with the functional role of autophagy in modulating muscle homeostasis and molecular mechanism regulating skeletal muscle mass. The chapters can be interesting for graduate students, postdocs, teachers, physicians, and for executives in biotech and pharmaceutical companies, as well as researchers in the fields of molecular biology and regenerative medicine.

The Voices and Rooms of European Bioethics

Authors: ---
ISBN: 9781315814469 Year: Pages: 210 DOI: 10.26530/OAPEN_575252 Language: English
Publisher: Taylor & Francis Grant: Wellcome Trust - 097725
Subject: Biology
Added to DOAB on : 2015-09-15 11:01:13
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This book reflects on the many contributions made in and to European bioethics to date, in various locations, and from various disciplinary perspectives. In so doing, the book advances understanding of the academic and social status of European bioethics as it is being supported and practiced by various disciplines such as philosophy, law, medicine, and the social sciences, applied to a wide range of areas. The European focus offers a valuable counter-balance to an often prominent US understanding of bioethics. The volume is split into four parts. The first contains reflection on bioethics in the past, present and future, and also considers how comparison between countries and disciplines can enrich bioethical discourse. The second looks at bioethics in particular locations and contexts, including: policy, boardrooms and courtrooms; studios and virtual rooms; and society, while the third part explores the translation of theories and concepts of bioethics into the clinical setting. The fourth and final section focuses on academic expressions of bioethics, as it is theorised in various disciplines and also as it is taught, whether in classrooms or at the patient’s bedside. The book features unique contributions from a range of experts including: Alastair V Campbell; Ruth Chadwick; Angus Dawson; Raymond G. De Vries; Suzanne Ost; Renzo Pegoraro; Rouven Porz; Paul Schotsmans;Jochen Vollmann; Guy Widdershoven and Hub Zwart.

‘You don’t Need Proof When You’ve Got Instinct!’: Gut Feelings and Some Limits to Parental Authority (Book chapter)

Book title: The Voices and Rooms of European Bioethics

Authors: ---
ISBN: 9780415737197 9781315814469 Year: Pages: 210 Language: English
Publisher: Taylor & Francis Grant: Wellcome Trust - 097725
Subject: Biology
Added to DOAB on : 2018-06-22 11:01:04
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This book reflects on the many contributions made in and to European bioethics to date, in various locations, and from various disciplinary perspectives. In so doing, the book advances understanding of the academic and social status of European bioethics as it is being supported and practiced by various disciplines such as philosophy, law, medicine, and the social sciences, applied to a wide range of areas. The European focus offers a valuable counter-balance to an often prominent US understanding of bioethics. The volume is split into four parts. The first contains reflection on bioethics in the past, present and future, and also considers how comparison between countries and disciplines can enrich bioethical discourse. The second looks at bioethics in particular locations and contexts, including: policy, boardrooms and courtrooms; studios and virtual rooms; and society, while the third part explores the translation of theories and concepts of bioethics into the clinical setting. The fourth and final section focuses on academic expressions of bioethics, as it is theorised in various disciplines and also as it is taught, whether in classrooms or at the patient’s bedside. The book features unique contributions from a range of experts including: Alastair V Campbell; Ruth Chadwick; Angus Dawson; Raymond G. De Vries; Suzanne Ost; Renzo Pegoraro; Rouven Porz; Paul Schotsmans;Jochen Vollmann; Guy Widdershoven and Hub Zwart.

Stress in Post-War Britain

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Book Series: Studies for the Society for the Social History of Medicine ISBN: 9781315654096 9781848934733 9781138630130 9781317318040 9781317318033 9781317318026 Year: DOI: 10.4324/9781315654096 Language: English
Publisher: Taylor & Francis
Subject: Medicine (General) --- Social Sciences
Added to DOAB on : 2019-11-08 11:21:11
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In the years following World War II the health and well-being of the nation was of primary concern to the British government. The essays in this collection examine the relationship between health and stress in post-war Britain through a series of carefully connected case studies.

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Interface Oral Health Science 2014

Authors: --- ---
ISBN: 9784431551256 9784431551928 Year: Volume: 1 Pages: 351 DOI: 10.1007/978-4-431-55192-8 Language: English
Publisher: Springer
Subject: Dentistry
Added to DOAB on : 2015-07-24 16:40:46
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The Tohoku University Graduate School of Dentistry first introduced the concept of “Interface Oral Health Science”, designed to establish and maintain healthy oral cavities, which are home to a number of mixed systems. Included in those systems are: (1) host tissues such as teeth, mucosa, muscle and bone, (2) parasites and microorganisms cohabiting the surfaces of the oral cavity and (3) biomaterials that are used for the rehabilitation of oral functions. In addition, (4) these systems are subject to severe and complex mechanical forces. Therefore, it is critical to promote dental studies that integrate a wide range of interdisciplinary research as medicine, agriculture, material science, engineering, and pharmacology. With this incentive, international symposiums for interface oral health science have been held several times in the past. The concept has since refined and expanded, the result being the “Biosis-Abiosis Intelligent Interface,” and projects aiming at the creation of highly functional and autonomic intelligent interfaces are ongoing. This book brings together a number of studies on incentives and projects by leading authors. Topics include biosis-abiosis interface of dental implants, biomaterials in interface science, biomedical engineering interface and cell manipulation and tissue regeneration. Readers not only from the field of dentistry but also many related areas will find this book a valuable resource.

Marking the Face, Curing the Soul? Reading the Disfigurement of Women in the Later Middle Ages (Book chapter)

Book title: Medicine, Religion and Gender in Medieval Culture

Author:
ISBN: 9781843844013 Year: Pages: 26 Language: English
Publisher: Boydell & Brewer Grant: Wellcome Trust - 097469
Subject: Medicine (General) --- Languages and Literatures
Added to DOAB on : 2018-06-22 11:01:04
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Current preoccupations with the body have led to a growing interest in the intersections between religion, literature and the history of medicine, and, more specifically, how they converge within a given culture. This collection of essays explores the ways in which aspects of medieval culture were predicated upon an interaction between medical and religious discourses, particularly those inflected by contemporary gendered ideologies. The essays interrogate this convergence broadly in a number of different ways: textually, conceptually, historically, socially and culturally. They argue for an inextricable relationship between the physical and spiritual in accounts of health, illness and disability, and demonstrate how medical, religious and gender discourses were integrated in medieval culture. Naoë Kukita Yoshikawa is Professor of English in the Faculty of Humanities and Social Sciences at Shizuoka University.&#xD;&#xD;Contributors: Louise M. Bishop, Elma Brenner, Joy Hawkins, Roberta Magnani, Takami Matsuda, Liz Herbert McAvoy, Irina Metzler, Denis Renevey, Patricia Skinner, Juliette Vuille, Diane Watt, Naoë Kukita Yoshikawa.

Drug Discovery and Development - From Molecules to Medicine

Authors: ---
ISBN: 9789535121282 9789535142225 Year: Pages: 330 DOI: 10.5772/58659 Language: English
Publisher: IntechOpen
Subject: Oncology
Added to DOAB on : 2019-10-03 09:47:09

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It is very important for scientists all over the globe to enhance drug discovery research for better human health. This book demonstrates that various expertise are essential for drug discovery including synthetic or natural drugs, clinical pharmacology, receptor identification, drug metabolism, pharmacodynamic and pharmacokinetic research. The following 5 sections cover diverse chapter topics in drug discovery: Natural Products as Sources of Leading Molecules in Drug Discovery; Oncology and Drug Discovery; Receptors Involvement in Drug Discovery; Management and Development of Drugs against Infectious Diseases; Advanced Methodology.

A COPD Primer

Authors: ---
ISBN: 9783110468007 9783110468113 Year: Pages: 412 DOI: 10.1515/9783110468007 Language: English
Publisher: De Gruyter
Subject: Internal medicine
Added to DOAB on : 2016-01-07 14:19:43
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In 2012 we received a grant from the Veterans Health Administration Office of Specialty Care entitled, “Patient-Centered Model for the Management of Chronic Obstructive Pulmonary Disease.” The grant’s goals were to enhance the recognition and diagnosis of COPD and implement a Patient-Centered Model for the Management of COPD. As the work on that proposal progressed, we realized that providers did not have an up-to-date, comprehensive, easily read, “how to” manual for the management of COPD despite all the advances in COPD care that have occurred over the past 5 years. Consensus documents such as the VA-DOD Guidelines were abbreviated summaries that were rarely used. From those discussions, the concept for this volume, a COPD Primer, developed. The goal was to develop a practical book that concisely presented COPD to providers with sufficient background and explanation of the physiologic and scientific rationale for various management strategies without becoming an esoteric academic work. We hope that this COPD Primer has achieved that goal and will be a useful, practical text for practitioners and medical trainees alike.The COPD Primer begins with an examination of what COPD is; it is really a syndrome, a constellation of historical features and clinical, physiologic, and radiographic findings. However, those elements come together in many different ways to create multiple different COPD phenotypes that are only now being recognized and used to define specific management strategies. COPD research has progressed beyond the simple classification of “blue bloaters” and “pink puffers.” Next, the epidemiology and economic consequences of COPD are reviewed. Bill Eschenbacher presents an approach to the patient with respiratory symptoms with detailed discussions of pulmonary function testing and how airflow limitation/obstruction is identified by spirometry and the use of lung imaging to identify individuals with COPD. Michael Borchers and Gregory Motz summarize current evidence implicating genetics, proteolytic imbalance, oxidative stress, inflammation, occupational and environmental exposures, and innate and adaptive immune function in the pathogenesis of COPD and the implication of these findings to future treatments. The single most important intervention in the prevention and treatment of COPD is smoking cessation. Shari Altum, Katherine Butler, and Rachel Juran present a practical approach to smoking cessation utilizing motivational interviewing in combination with pharmacologic interventions. Then, they expand upon these concepts to provide practitioners with convenient, realistic suggestions to encourage patient self-management in all aspects of COPD care and overall health. Ahsan Zafar reviews the natural history, recently described COPD phenotypes, and gender differences that clearly illustrate the broad spectrum of disease that comprises the term, COPD. The cover illustration highlights Dr. Zafar’s creative and artistic talents. The extensive nonpulmonary aspects of COPD are reviewed by Ralph Panos in an examination of COPD’s multi-organ manifestations. Next, the effect of COPD on sleep and the overlap syndrome, the concurrence of COPD and obstructive sleep apnea, and its consequences are presented. Jean Elwing examines the effect of COPD on the pulmonary vasculature with a detailed discussion of the evaluation and management of pulmonary hypertension associated with COPD. COPD’s effects on psychosocial functioning and familial interactions are presented by Mary Panos and Ralph Panos.The focus of the Primer then shifts from manifestations to treatment with a discussion of stable COPD management. With the current plethora of devices for delivering respiratory medications, it is difficult for both patients and providers to sustain knowledge of their proper use. Aaron Mulhall presents a practical guide to correct inhaler use that reviews all the current devices. Folarin Sogbetun then reviews the management of outpatient COPD exacerbations and Nishant Gupta discusses the approach to the patient hospitalized with COPD. Because patients with COPD often see multiple subspecialty physicians in addition to their primary care providers, interdisciplinary communication and coordination of care is essential for their management; Sara Krzywkowski-Mohn reviews the interactions between primary and specialty care for the patient with COPD with suggestions for improved communication and care coordination. Finally, advance care planning including palliative care and hospice is reviewed with a discussion of how end stage COPD affects not only the patient but also their family and social network.This COPD Primer incorporates the knowledge that we have learned over the past several years during the development and implementation of a patient-centered model for the management of COPD. It was written with the explicit goal of assisting both the practicing provider and medical trainee in the care of patients with COPD.

Early Twentieth-Century Self-Harm: Cut Throats, General and Mental Medicine (Book chapter)

Book title: A History of Self-Harm in Britain

Author:
ISBN: 9781137529619 Year: Pages: 268 Language: English
Publisher: Palgrave Macmillan Grant: Wellcome Trust - 89708
Subject: Medicine (General)
Added to DOAB on : 2019-01-15 13:34:48

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This book is the first account of self-harming behaviour in its proper historical and political context. The rise of self-cutting and overdosing in the 20th century is linked to the sweeping changes in mental and physical health, and wider political context. The welfare state, social work, Second World War, closure of the asylums, even the legalization of suicide, are all implicated in the prominence of self harm in Britain. The rise of 'overdosing as a cry for help' is linked to the integration of mental and physical healthcare, the NHS, and the change in the law on suicide and attempted suicide. The shift from overdosing to self-cutting as the most prominent 'self-damaging' behaviour is also explained, linked to changes in hospital organization and the wider rise of neoliberal politics. Appreciation of history and politics is vital to understanding the psychological concerns over these self-harming behaviours.

Onkologie für die Palliativmedizin

Authors: --- ---
ISBN: 9783863952297 Year: DOI: 10.17875/gup2015-850 Language: German
Publisher: Universitätsverlag Göttingen
Subject: Medicine (General)
Added to DOAB on : 2016-06-21 11:02:24
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Über 90% der in der spezialisierten Palliativversorgung betreuten Patienten leiden an einer Krebserkrankung. Sowohl der Impuls einer frühzeitigen, bedürfnisorientierten palliativmedizinischen Mitbehandlung als auch die erheblichen Weiterentwicklungen einer (zunehmend molekular definierten) Onkologie erfordern, dass auch die in der Palliativversorgung Tätigen ein Grundverständnis von Tumorbiologie, von modernen onkologischen Therapiekonzepten und von supportivtherapeutischen Möglichkeiten haben. Dieses Buch möchte dieses Grundverständnis von Krebs und onkologischer Behandlung in einer auch für Nicht-Onkologen verständlichen Form vermitteln und richtet sich vor allem an jene, die in der palliativmedizinischen Betreuung krebskranker Menschen involviert sind: Palliativärzte, Palliativpflegende, aber auch Haus- und Fachärzte, Physiotherapeuten, Seelsorger, Psychotherapeuten und viele mehr. Es will kein Lehrbuch der Onkologie ersetzen, sondern eine praxisorientierte, therapie- und versorgungsrelevante Hilfestellung im (palliativ-)medizinischen Arbeitsalltag sein – dort, wo es um eine umfassende Unterstützung von Krebspatienten geht. Das Buch ist ein Projekt der „AG Interdisziplinäre Onkologie“ der Deutschen Gesellschaft für Palliativmedizin (DGP).

Keywords

cancer --- medicine --- therapy

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