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Stochastische Simulation von Energieflüssen im NutzfahrzeugEin einsatzorientiertes Bewertungs- und Optimierungsverfahren

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Book Series: Karlsruher Schriftenreihe Fahrzeugsystemtechnik / Institut für Fahrzeugsystemtechnik ISSN: 18696058 ISBN: 9783731504030 Year: Volume: 38 Pages: XX, 317 p. DOI: 10.5445/KSP/1000047790 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:02:02
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This book proposes a stochastic simulation process as an efficient approach to consumption simulation. The process complements the explicit transient analysis. Thereby, it takes into account statistically evaluated vehicle and route data and calculates a probability distribution of the energy savings which can be achieved by specific measures.

Hormonal and Neuroendocrine Regulation of Energy Balance

Authors: ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889198856 Year: Pages: 117 DOI: 10.3389/978-2-88919-885-6 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Physiology
Added to DOAB on : 2016-01-19 14:05:46
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Alteration in adequate energy balance maintenance results in serious disturbances such as obesity and its related metabolic disorders. In Mammals, energy balance is homeostatically controlled through hormonal and neuroendocrine systems which cooperation is based on cross-talk between central and peripheral signals. The hypothalamus as well as peripheral hormones among which adipokines from adipose tissue and thyroid hormones play a crucial role in energy homeostasis. Unraveling the physiological, cellular and molecular mechanisms through which hormonal and neuroendocrine systems regulate energy balance has been a long-standing challenge in biology and is now more necessary when considering the world-wide increasing prevalence of obesity. Indeed, recognizing and understanding the biochemical and nutrient signaling pathways contributing to the nervous and endocrine integration of physiological mechanisms involved in the normal and/or abnormal regulation of energy balance is fundamental also to the development of new, effective, and targeted treatments for obesity. Recent studies have highlighted the role of hypothalamic pro-opiomelanocortin-expressing neurons in the regulation of energy homeostasis by controlling energy expenditure and food intake. This is accomplished through a precise balance of production and degradation of a-melanocyte-stimulating hormone, an anorexigenic neuropeptide which is degraded to an inactive form unable to inhibit food intake by the key enzyme prolyl carboxypeptidase (PRCP), thus suggesting that pharmacologic approaches targeting PRCP may provide a novel and effective option for the management of obesity and its associated metabolic disorders. Indeed, efforts have been made to generate potent, brain-penetrant PRCP inhibitors. Weight loss due to negative energy balance is a goal for obese subjects not always reachable by dietary caloric restriction or increased physical activity. Lipid-lowering therapies have been suggested to have potential benefits, however, the establishment of comprehensive therapeutic strategies is still awaited. Recently, it has been reported that thyroid hormone (TH)- derivatives such as 3,5-diiodothyronine and 3-iodothyronamine possess interesting biological activities, opening new perspectives in thyroid physiology and TH derivatives therapeutic usage. Moreover, several studies, focusing on the interaction between thyroid hormone (TH), the autonomic nervous system and the liver, revealed an important role for the hypothalamus in the differential effects of TH on autonomic outflow to peripheral organs controlling energy balance. This Research Topic aims to give a comprehensive and integrate view of the factors involved in the endocrine and neuroendocrine signaling in energy balance regulation to highlight their involvement into physiological processes and regulatory systems as well as their perturbation during pathological processes.

The two-way link between eating behavior and brain metabolism

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889197057 Year: Pages: 197 DOI: 10.3389/978-2-88919-705-7 Language: English
Publisher: Frontiers Media SA
Subject: Psychology --- Science (General)
Added to DOAB on : 2016-04-07 11:22:02
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This research topic collected and connected information concerning both the underlying metabolic mechanisms and consequences of eating behaviors. These two aspects are tremendously important for a better understanding of eating behavior abnormalities as well as for improving education on eating disorders and behaviors.

Aging, neurogenesis and neuroinflammation in hearing loss and protection

Authors: --- ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889196449 Year: Pages: 151 DOI: 10.3389/978-2-88919-644-9 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Neurology
Added to DOAB on : 2016-08-16 10:34:25
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Worldwide, 278 million people are estimated to have moderate to profound hearing loss. Age-related hearing loss, also known as presbyacusis, affects approximately half of the population over 60 years old, making it the second most common cause of disability in older people. Hearing loss occurs when the sensory cells and neurons of the cochlea degenerate and die. The vestibular system, which holds the sense of balance, shares a common embryonic origin with the cochlea and together conform the inner ear. Balance problems are a trait of ageing to the point that balance ability is considered a sensor of physical decline and vestibular degeneration is the most common cause of falls in the elderly. Still the molecular bases of ageing in the vestibular system have not been studied in detail. Genetic and environmental factors contribute to the progression of age-related hearing loss (ARHL). Being noise the main environmental noxious agent for human hearing in the industrialized societies. There is no restorative treatment for deafness but functional replacement by means of prosthesis. Therefore, prevention and treatment of hearing loss is an unmet medical need. To develop innovative medical strategies against hearing loss, it is critical to understand the causes of ARHL and the essential pathways responsible for the manifestation of this complex disease. In this research topic, experts will discuss the stages and molecular elements of the damage and repair processes involved in ARHL, from cellular processes to molecules involved in aging. Oxidative stress takes a central stage as an essential element in the progression of injury and cell loss, and a target for cell protection strategies. Finally, the mechanisms of action and the potential of novel therapies for hair cell repair and protection will be discussed along with drug delivery strategies.

Integrated Soil and Water Management: Selected Papers from 2016 International SWAT Conference

Authors: --- --- --- --- et al.
ISBN: 9783038428152 9783038428169 Year: Pages: X, 490 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Environmental Sciences
Added to DOAB on : 2018-04-24 08:55:09
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Soil and water are two key life-sustaining resources on Earth. If not protected, both elements will become humanity’s worst nightmares. Uncontrollable water flows, polluted water, and lack of water on the one hand, and infertile soils, polluted soils, dust-storms, and topsoil erosion, on the other hand, can wreak havoc on human life and threaten its very existence. Ensuing dangers from climate change and population growth will further strain these resources. To stop disaster scenarios from happening, our only way is to manage these prized resources. Modeling programs, such as SWAT, are valuable tools in finding ways of combating food and water insecurity, and mitigating the impact of climate change and growing demands of resources. This Special Issue of Water is designed to show the results of analyses of scientists from all over the world in dealing with various environmental problems. The papers here are selected from the works presented at the 16th International SWAT conference held in Beijng. The information and analyses are intended to contribute to the development and implementation of effective soil and water management programs.

Evaluation of Building Resilience Under Earthquake Input Using Single, Double and Multiple Impulses

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889452705 Year: Pages: 61 DOI: 10.3389/978-2-88945-270-5 Language: English
Publisher: Frontiers Media SA
Subject: General and Civil Engineering --- Environmental Engineering
Added to DOAB on : 2018-11-16 17:17:57
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This eBook is the third in a series of books on the critical earthquake response of elastic or elastic-plastic structures under near-fault or long-duration ground motions, and includes four original research papers which were published in the specialty section Earthquake Engineering in ‘Frontiers in Built Environment’. Several extensions of the first eBook and the second eBook are included here. The first article is on the earthquake resilience of residential houses after repeated ground motions with high intensity. The 2016 Kumamoto earthquake brought a significant impact on the earthquake resilience of residential houses under repeated ground motions with high intensity in a few days. The necessary strength upgrade withstanding two repeated high-intensity ground motions was found to be 1.5. The second article is concerned with the smart enhancement of earthquake resilience of building structures under both near-fault and long-duration ground motions. A hybrid system of base-isolation and building connection control was proposed and its earthquake resilience to near-fault and long-duration ground motions was evaluated by a double impulse and a multiple impulse. It was demonstrated that the base-isolation is effective for near-fault ground motions and the building connection system using passive dampers is effective for long-duration ground motions. The third article is related to the robustness evaluation of elastic-plastic base-isolated high-rise buildings under resonant near-fault ground motions. The robustness function was introduced to evaluate quantitatively the robustness of elastic-plastic base-isolated high-rise buildings. The fourth article is an extension of the previously proposed energy balance approach to a bilinear elastic-plastic single-degree-of-freedom system under a long-duration sinusoidal ground motion. A historical difficulty in nonlinear vibration posed by Caughey (1960) and Iwan (1961) has been overcome in a smart manner after half a century. The approach presented in this eBook, together with the previous eBooks, is an epoch-making accomplishment to open the door for simpler and deeper understanding of structural reliability and resilience of built environments in the elastic-plastic and nonlinear range.

Melt Water Retention Processes in Snow and Firn on Ice Sheets and Glaciers: Observations and Modeling

Authors: --- --- ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889456192 Year: Pages: 160 DOI: 10.3389/978-2-88945-619-2 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Geography
Added to DOAB on : 2019-01-23 14:53:43
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Melt takes place where the surface of glaciers or ice sheets interacts with the atmosphere. While the processes governing surface melt are fairly well understood, the pathways of the meltwater, from its origin to the moment it leaves a glacier system, remain enigmatic. It is not even guaranteed that meltwater leaves a glacier or ice sheet. On Greenland, for example, only slightly more than 50% of the meltwater runs off. The remainder mostly refreezes within the so-called firn cover of the ice sheet. This eBook contains 11 studies which tackle the challenge of understanding meltwater retention in snow and firn from various angles. The studies focus both on mountain glaciers and on the Greenland ice sheet and address challenges such as measuring firn properties, quantifying their influence on meltwater retention, modelling firn processes and meltwater refreezing as well as unravelling the mechanisms within the recently discovered Greenland firn aquifers.

Evidence in Civil Law - Latvia

Authors: --- ---
Book Series: Law & Society ISBN: 9789616842532 Year: Pages: 94 DOI: 10.4335/978-961-6842-53-2 Language: English
Publisher: Institute for Local Self-Government and Public Procurement Maribor
Subject: Political Science
Added to DOAB on : 2015-11-09 21:56:58
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The national report of civil procedure in Latvia is based on review of the Latvian Civil Procedure Law, court practice, feedback by the Ministry of Justice on cooperation with the EU states as well as with third countries in various matters of jurisdiction as well as on legal science. Civil procedure includes all legal principles like disposition, right to be present and to be heard, competition of parties in gaining all necessary evidence and similar concepts to be found in almost every modern civil procedure system. However, there are certain specific features due to which Latvian process stands out. For instance, there is still a system of legal presumptions which apparently is inherited from Roman law, yet still prescribed by the Latvian Civil law (Civil code). Also certain degree of formal attitude remains as a characteristic feature of the Latvian civil procedure.

Remote Sensing of Evapotranspiration (ET)

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ISBN: 9783039216024 9783039216031 Year: Pages: 240 DOI: 10.3390/books978-3-03921-603-1 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- Biotechnology
Added to DOAB on : 2019-12-09 11:49:15
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Evapotranspiration (ET) is a critical component of the water and energy balances, and the number of remote sensing-based ET products and estimation methods has increased in recent years. Various aspects of remote sensing of ET are reported in the 11 papers published in this book. The major research areas covered by this book include inter-comparison and performance evaluation of widely used one- and two-source energy balance models, a new dual-source model (Soil Plant Atmosphere and Remote Sensing Evapotranspiration, SPARSE), and a process-based model (ETMonitor); assessment of multi-source (e.g., remote sensing, reanalysis, and land surface model) ET products; development or improvement of data fusion frameworks to predict continuous daily ET at a high spatial resolution (field-scale or 30 m) by fusing the advanced spaceborne thermal emission reflectance radiometer (ASTER), the moderate resolution imaging spectroradiometer (MODIS), and Landsat data; and investigating uncertainties in ET estimates using an ET ensemble composed of several land surface models and diagnostic datasets. The effects of the differences between ET products on water resources and ecosystem management were also investigated. More accurate ET estimates and improved understanding of remotely sensed ET products are crucial for maximizing crop productivity while minimizing water losses and management costs.

Resurgent Asia

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ISBN: 9780198849513 Year: Pages: 320 DOI: 10.1093/oso/9780198849513.001.0001 Language: English
Publisher: Oxford University Press Grant: UNU WIDER
Subject: Economics --- Political Science
Added to DOAB on : 2020-06-03 23:56:40
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Resurgent Asia analyses the phenomenal transformation of Asia, which would have been difficult to imagine, let alone predict, fifty years ago, when Gunnar Myrdal published Asian Drama. In doing so, it provides an analytical narrative of this remarkable story of economic development, situated in its wider context of historical, political, and social factors, and an economic analysis of the underlying factors, with a focus on critical issues in the process of, and outcomes in, development. In 1970, Asia was the poorest continent in the world, marginal except for its large population. By 2016, it accounted for three-tenths of world income, two-fifths of world manufacturing, and one-third of world trade, while its income per capita converged towards the world average. However, this transformation was associated with unequal outcomes across countries and between people. The analysis disaggregates Asia into its four constituent sub-regions—East, Southeast, South, and West—and further into fourteen economies—China, India, South Korea, Indonesia, Turkey, Taiwan, Thailand, Philippines, Malaysia, Singapore, Pakistan, Bangladesh, Vietnam, and Sri Lanka—which account for more than four-fifths of its population and income. This book enhances our understanding of development processes and outcomes in Asia over the past fifty years, draws out the analytical conclusions that contribute to contemporary debates on development, and highlights some lessons from the Asian experience for countries elsewhere. It is the first to examine the phenomenal changes that are transforming economies in Asia and shifting the balance of economic power in the world, while reflecting on the future prospects in Asia over the next twenty-five years. A rich, engaging, and fascinating read.

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