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Chapter Twelve Revealing the Hidden Affliction (Book chapter)

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ISBN: 9781580469616 Year: Pages: 47 Language: English
Publisher: University of Rochester Press Grant: Wellcome Trust - 605972
Subject: Medicine (General)
Added to DOAB on : 2019-10-09 11:21:13
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Abstract

By the turn of the twentieth century the British nation’s declining birthrate was increasingly the subject of anxious public and scientific debate, as the Registrar General’s annual reports continued to confirm a downward national trend, which had in fact commenced from the late 1870s.

Introduction (Book chapter)

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ISBN: 9781580469616 Year: Pages: 40 Language: English
Publisher: University of Rochester Press Grant: Wellcome Trust - 605972
Subject: Medicine (General)
Added to DOAB on : 2019-10-09 11:21:14
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Abstract

This volume is a necessarily multidisciplinary collection dedicated to the extremely difficult task of uncovering and exploring what can be reconstructed of the dimensions and the scale of the historical impact of sexually transmitted infections (STIs) on human infertility. As a subject for inquiry, this comes close to Winston Churchill’s celebrated phrase, “a riddle, wrapped in a mystery, inside an enigma.”

Menstrual Cycle

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ISBN: 9781789239348 9781789856736 9781789856743 Year: Pages: 146 DOI: 10.5772/intechopen.76123 Language: English
Publisher: IntechOpen
Subject: Gynecology and Obstetrics --- Internal medicine
Added to DOAB on : 2019-10-03 07:51:53

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Abstract

In this book, Menstrual Cycle, we cover certain interesting aspects of the physiology and endocrinology of the female body, as well as clinical diagnosis and treatment of various gynecological diseases and disorders in women of reproductive age. In this way, scholars, postgraduates, students, and others will be able to become acquainted with modern scientific research into menstrual cycle. For others, this book will be the impetus for further research in this area.

Estrogen

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ISBN: 9781838808662 9781838808679 9781838808686 Year: Pages: 88 DOI: 10.5772/intechopen.73419 Language: English
Publisher: IntechOpen
Subject: Gynecology and Obstetrics --- Internal medicine
Added to DOAB on : 2019-10-03 07:51:53

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Abstract

This short book contains the most up to date thinking on estrogen and its related functions. Here, the reader will find thoughtful writings on various topics by renowned authors in their respective fields. This book aims to serve as a compressive guide on estrogen function.

Molecular Research of Endometrial Pathophysiology

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ISBN: 9783039214952 9783039214969 Year: Pages: 378 DOI: 10.3390/books978-3-03921-496-9 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Social Sciences --- Sociology
Added to DOAB on : 2019-12-09 16:10:12
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Abstract

The endometrium has been the subject of intense research in a variety of clinical settings, because of its importance in the reproductive process and its role in women’s health. In the past 15 years, significant efforts have been invested in defining the molecular phenotype of the receptive phase endometrium as well as of various endometrial pathologies. Although this has generated a wealth of information on the molecular landscape of human endometrium, there is a need to complement this information in light of the novel methodologies and innovative technical approaches. The focus of this International Journal of Molecular Sciences Special Issue is on molecular and cellular mechanisms of endometrium and endometrium-related disorders. The progress made in the molecular actions of steroids, in the metabolism of steroids and intracrinology, in endometrial intracellular pathways, in stem cells biology, as well as in the molecular alterations underlying endometrium-related pathologies has been the focus of the reviews and papers included.

Keywords

RANK --- endometrium --- endometrial cancer --- prognosis --- immunohistochemistry --- gene expression --- endometriosis --- developmental pathway --- pathogenomics --- mesenchymal stem cells --- endometrial cancer --- mtDNA mutations --- deficit of complex I --- antioxidant response --- mitochondrial biogenesis --- mitochondrial dynamics --- mitophagy --- miRNA --- lncRNAs --- endometrial cancer --- endometriosis --- chronic endometritis --- cell contacts --- tight junction --- adherens junction --- gap junction --- endometrium --- implantation --- decidualization --- endometriosis --- endometrial cancer --- liquid biopsy --- uterine aspirate --- circulating tumour cells (CTCs) --- circulating tumour DNA (ctDNA) --- exosomes --- Vitamin D --- endometrium --- endometrial cancer --- endometrial cancer --- preclinical models --- translational research --- endometrial cancer --- type II endometrial carcinoma --- targeted therapy --- kinase inhibitor --- molecular marker --- protein kinase --- protein phosphatase --- PP2A --- PPP2R1A --- SMAP --- endometriosis --- infertility --- niche --- inflammation --- immunomodulation --- mesenchymal stem cell --- orthoxenograft --- uterine cancer --- avatar --- murine models --- personalized medicine --- targeted therapy --- preclinical studies --- translational research --- endometriosis --- TRP channels --- endometrial stromal cells --- eutopic and ectopic endometrium --- endometrial cell --- pathway --- proliferation --- decidualization --- migration --- angiogenesis --- regeneration --- breakdown --- implantation --- endometrial cancer --- orthotopic xenograft model --- estrogen dependent --- bioluminescence imaging --- contrast-enhanced CT scan --- endometrium --- adult stem cells --- endometrial regeneration --- stem cell markers --- endometriosis --- endometrial cancer --- decidualisation --- oestradiol --- aromatase --- testosterone --- dehydroepiandrosterone (DHEA) --- endometriosis --- endometrial cancer --- sulfatase --- endometriosis --- ectopic stroma --- microRNA --- small RNA sequencing --- EDN1 --- HOXA10 --- miR-139-5p --- miR-375 --- CTCF --- tumour suppressor gene --- haploinsufficiency --- zinc finger --- CRISPR/Cas9 --- cancer --- endometrial cancer --- gene editing --- phosphoinositide 3-kinase --- PIK3CA --- PIK3CB --- p110? --- p110? --- endometrial cancer --- LGR5 --- endometrium --- endometriosis --- menstrual cycle --- macrophages

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