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Thyroid Disorders

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ISBN: 9781789857856 9781789857863 Year: Pages: 80 DOI: 10.5772/intechopen.72980 Language: English
Publisher: IntechOpen
Subject: Internal medicine
Added to DOAB on : 2019-10-03 07:51:53

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This is a small book containing various aspects of thyroid gland disorders. Congenital hypothyroidism chapter emphasizes early diagnosis in prevention of irreparable damage to growth and brain of infants. Role of nuclear medicine in diagnosis and treatment is outlined. Last few chapters deal with congenital hypothyroidism, thyroid carcinoma, its diagnosis, treatment and preservation of posterior parathyroid gland during thyroid surgery. The purpose of the book is to disseminate knowledge on thyroid diseases. It will be a good reference book both for students of medicine and general practitioners.

Celiac Disease - From the Bench to the Clinic

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ISBN: 9781789850499 9781789850505 Year: Pages: 100 DOI: 10.5772/intechopen.73847 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:52

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Celiac disease (CD) occurs in about 1% of people worldwide. Diagnosis rates are increasing due to a true rise in incidence, rather than increased awareness and detection. CD affects genetically susceptible individuals who are triggered by the ingestion of gluten. The disease has many clinical manifestations, ranging from severe to minimally symptomatic or non-symptomatic presentations. Diagnosis requires the presence of duodenal chronic inflammation, and most patients have circulating antibodies against tissue transglutaminase. Our understanding of the basic and clinical aspects of CD increases, which is as a major health problem of almost global occurrence. Case finding, distinguishing CD from other gluten-sensitive conditions, better care, and balanced use of resources are the current challenges.

Chronic Autoimmune Epithelitis - Sjogren's Syndrome and Other Autoimmune Diseases of the Exocrine Glands

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Book Series: Rheumatology ISSN: 26319233 ISBN: 9781789852110 9781789852127 9781789854152 Year: Volume: 3 Pages: 120 DOI: 10.5772/intechopen.73892 Language: English
Publisher: IntechOpen
Subject: Microbiology
Added to DOAB on : 2019-10-03 07:51:53

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Epithelial tissue does not spring to mind as an obvious source of autoimmune phenomena. Yet, genetic predisposition and influence of various environmental and epigenetic factors may lead to epithelium becoming a springboard for the development of autoimmune diseases, such as Sjögren’s syndrome, primary biliary cholangitis, autoimmune pancreatitis, or IgG4-related diseases. This book is intended as an introduction to the problem of “autoimmune epithelitis” and diseases closely related to the immune disturbances of the epithelium, with special emphasis on those affecting exocrine glands. Both theoretical and practical knowledge, presented by authors from a wide range of medical specialties, should be of help for medical professionals who have to deal with this difficult problem in their daily practice.

Resveratrol - Adding Life to Years, Not Adding Years to Life

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ISBN: 9781789849943 9781789849950 Year: Pages: 166 DOI: 10.5772/intechopen.74428 Language: English
Publisher: IntechOpen
Subject: Pharmacy and materia medica
Added to DOAB on : 2019-10-03 07:51:52

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This book intends to strike a balance between developments in research and the fact that researchers must absorb and link to scientific advances with clinical practice so that the management of diseases can be based on sound physiological concepts. This book addresses several controversial issues regarding a natural molecule with fascinating pharmacological and therapeutic effects. The book contains three sections: Section 1: Pharmacology and Therapeutic Applications of Resveratrol; Section 2: Bioavailability, Metabolism, and Mode of Action of Resveratrol; Section 3: Resveratrol and Its Role in Chronic and Degenerative Diseases. Does it Add Life to Years or Years to Life? It is our hope that this book will motivate readers to approach the evidence on the use resveratrol and thereby spark an interest in making further contributions to the current scientific debate and treatment development efforts.

The Biopsychosocial Model of Health and Disease

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ISBN: 9783030118990 Year: Pages: 149 DOI: 10.1007/978-3-030-11899-0 Language: English
Publisher: Springer Nature Grant: Wellcome Trust - 605994
Subject: Science (General) --- Psychiatry --- Psychology --- Philosophy
Added to DOAB on : 2020-02-05 11:21:10
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This open access book is a systematic update of the philosophical and scientific foundations of the biopsychosocial model of health, disease and healthcare. First proposed by George Engel 40 years ago, the Biopsychosocial Model is much cited in healthcare settings worldwide, but has been increasingly criticised for being vague, lacking in content, and in need of reworking in the light of recent developments. The book confronts the rapid changes to psychological science, neuroscience, healthcare, and philosophy that have occurred since the model was first proposed and addresses key issues such as the model’s scientific basis, clinical utility, and philosophical coherence. The authors conceptualise biology and the psychosocial as in the same ontological space, interlinked by systems of communication-based regulatory control which constitute a new kind of causation. These are distinguished from physical and chemical laws, most clearly because they can break down, thus providing the basis for difference between health and disease. This work offers an urgent update to the model’s scientific and philosophical foundations, providing a new and coherent account of causal interactions between the biological, the psychological and social.

Molecular Pharmacology and Pathology of Strokes

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ISBN: 9783038975410 9783038975427 Year: Pages: 152 DOI: 10.3390/books978-3-03897-542-7 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics --- Cardiovascular
Added to DOAB on : 2019-02-11 11:33:53
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Stroke, a progressively non-communicable disease, is the second leading cause of death after coronary heart disease in developed countries. The present treatment options for stroke are adapting lifestyle practices, diabetes treatment, drugs, and the management of other factors, but no cure is yet available, despite new insights into molecular and therapeutic targets. Discoveries related to explicating the molecular pharmacology in cerebrovascular function and thrombosis have led to significant advancements in the current treatment paradigm for patients with stroke. Hence, this Special Issue invited scientific papers and reviews from researchers to provide solid evidence from a molecular point of view to scrutinize the molecular pharmacology and pathology of strokes. Platelet activation plays a major role in cardio and cerebrovascular diseases. Platelets also play a key role in the hemostatic process and are associated with various pathological events, such as arterial thrombosis and atherosclerosis. While the currently used anti-platelet drugs such as aspirin and clopidogrel demonstrate efficacy in many patients, they exert undesirable side effects. Therefore, the development of effective therapeutic strategies for the prevention and treatment of thrombotic diseases is a significant priority. Recently, precious metal drugs have conquered the subject of metal-based drugs, and several investigators have moved their attention to the synthesis of various ruthenium (Ru) and iridium (Ir) complexes due to their prospective therapeutic values. We have published this e-book about the “Molecular Pharmacology and Pathology of Strokes” and anticipate that readers will find this book useful regarding the significant challenges and current advances that are presently being made in stroke research, with the possibility of inspiring the application of novel drug development to enrich the devotion and treatment of patients with cardiovascular diseases.

Natural Compounds as New Cancer Treatments

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ISBN: 9783039213658 9783039213665 Year: Pages: 128 DOI: 10.3390/books978-3-03921-366-5 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General)
Added to DOAB on : 2019-12-09 11:49:15
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Cancer remains one of the main causes of morbidity and mortality worldwide. Although many pharmacological and clinical advances have been made, there is a constant need for new molecules to improve the overall options for treatment. Natural compounds from animal, microbial, vegetal, or fungal origin represent countless sources of new compounds that can be used as anticancer drugs, provided their activity, bioavailability, and toxicity are adequate. This book aims to compile both original articles and reviews that cover the most recent advances in the use of natural compounds for cancer treatment, and provide new objectives and advice for future research in the field of biological activity of natural compounds.

Cadmium Sources and Toxicity

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ISBN: 9783038979845 9783038979852 Year: Pages: 130 DOI: 10.3390/books978-3-03897-985-2 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Public Health
Added to DOAB on : 2019-06-26 08:44:06
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Cadmium (Cd) is an environmental toxicant of continuing public health concern worldwide, because total diet studies have shown that Cd is present in virtually all foodstuffs. Consequently, foods that are frequently consumed in large quantities, such as rice, potatoes, wheat, leafy salad vegetables, and other cereal crops, are the most significant dietary Cd sources. Moreover, Cd has chemical propensities that confer the potential to interfere with the physiological functions of calcium and zinc. Evidence of a wide range of diverse, toxic effects of Cd is increasingly apparent. In this collection, environmental Cd exposure is linked to an increased risk of chronic kidney disease that is known to be a cause of morbidity and mortality worldwide. Cd is also implicated in an early onset of menarche and deaths from cancer, especially in the uterus, kidney, and urinary tract. Moreover, Cd-induced kidney injury is replicated in Sprague Dawley rats, as is Cd-induced periodontal disease. Experimental studies suggest that the development of kidneys in fetuses and the function of insulin-producing cells may be adversely affected by Cd and that metformin, an anti-diabetic drug, is ineffective in Cd-intoxicated Wistar rats.

Pharmacist Services

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ISBN: 9783039217540 9783039217557 Year: Pages: 436 DOI: 10.3390/books978-3-03921-755-7 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Pharmacy and materia medica
Added to DOAB on : 2019-12-09 11:49:16
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The overall goal of this book is to give the reader a state-of-the-art synopsis of the pharmacist services domain. To accomplish this goal, the authors have addressed the social, psychosocial, political, legal, historic, clinical, and economic factors that are associated with pharmacist services. In this book, you will gain cutting-edge insights from learning about the research of experts throughout the world. The findings have relevance for enhancing pharmacist professionalism, pharmacist practice, and the progression of pharmacist services in the future.

Keywords

ambulatory care --- pharmacy practice faculty --- pharmacy learners --- clinical practice --- pharmacist services --- community pharmacy practice --- dispensing --- counselling --- pharmaceutical intervention --- pharmaceutical care --- observation --- immunization programs --- mobile health units --- experiential learning --- billing --- healthy people 2020 --- pharmacy --- emergency unit --- health workers --- cystic fibrosis --- pharmacists --- pharmacy services, medication management --- medication use burden --- travel --- immunization --- vaccination --- pharmacist --- community pharmacy --- pharmacy intern --- student pharmacist --- primary care --- interprofessional --- federally qualified health center --- serviced marketing --- design thinking --- medication synchronization --- community pharmacists --- innovation science --- adherence --- competitive advantage --- age disparities --- gender disparities --- job satisfaction --- job-related preferences --- pharmacist workforce --- pharmacists --- pharmacy education --- interprofessional practice and education --- community pharmacy --- medication therapy management --- medication-related problems --- medication discrepancies --- continuity of patient care --- cost avoidance --- Comprehensive Medication Management --- pharmaceutical care --- primary health care --- chronic diseases --- clinical results --- naltrexone --- opioid use disorder --- implementation --- service process --- regulatory --- community pharmacy --- pharmacist services --- opioid --- communication --- naloxone --- misuse --- disposal --- safety --- counseling --- comprehensive medication review --- community pharmacy --- collaboration --- community pharmacy --- pharmaceutical care --- medication therapy management --- pharmacy practice --- pharmacy education --- grants --- pharmacy benefit manager (PBM) --- ethics --- pharmaceutical regulation --- health care policy --- decision-making --- organizations --- ethical models --- code of ethics --- pharmacist --- adverse drug events --- brown bag --- pharmacy --- medication reconciliation --- pharmacy clinical services --- comprehensive medication management services --- medication experience --- pharmaceutical care practice --- documentation --- focus groups --- community pharmacy --- retail clinics --- pharmacists --- nurse practitioners --- interprofessional training --- primary care --- healthcare access --- community pharmacy --- pharmacist services --- wellness programs --- medication adherence --- quality measurement/benchmarking --- multiple chronic conditions --- CMS Star rating --- chronic kidney disease --- interprofessional care --- quality assurance --- pharmacy communication --- cue orientation --- focus group interviews --- Denmark --- transitions in care --- pharmacist --- medication therapy problems --- medication safety --- comprehensive medication management --- readmissions --- intention --- medication therapy management --- pharmacy services --- South Asian --- theory of planned behavior. --- pharmacist services --- community pharmacy --- care plan --- compensation --- primary health care --- information sharing --- qualitative research --- comparative case study --- value --- human papilloma virus --- HPV vaccination --- pharmacy --- coordinated care --- history of pharmacy --- 20th century history --- 21st century history --- community pharmacy services --- pharmacy education --- pharmacist --- services marketing --- management --- value-added services --- community-based pharmacy --- community-based pharmacist practitioners --- community pharmacy services --- health policy --- interrupted time series analysis --- medication reconciliation --- mental health care --- pharmacy staff --- mental health first aid --- mental illness --- pharmacist roles --- n/a --- collaborative practice --- clinical pharmacy --- advanced practice pharmacist provider

One Health and Zoonoses

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ISBN: 9783039212958 9783039212965 Year: Pages: 140 DOI: 10.3390/books978-3-03921-296-5 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Public Health
Added to DOAB on : 2019-12-09 16:10:12
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The One Health concept recognizes that the health of humans, animals, and their ecosystems are interconnected, and that a coordinated, collaborative, multidisciplinary, and cross-sectoral approach is necessary to fully understand and respond to potential or existing risks that originate at the animal–human–ecosystems interfaces. Thus, the One Health concept represents a holistic vision for addressing some of the complex challenges that threaten human and animal health, food safety, and the environments in which diseases flourish. There are many examples showing how the health of humans is related to the health of animals and the environment. Diseases shared between humans and animals are zoonoses. Some zoonoses have been known for many years, whereas others have emerged suddenly and unexpectedly. Over 70% of all new emerging diseases over the past few decades have been zoonoses that have emerged from wildlife, most often from bats, rodents, or birds. Examples of zoonoses are many and varied, ranging from rabies to bovine tuberculosis, and from Japanese encephalitis to SARS. Clearly, a One Health approach is essential for understanding their ecology, and for outbreak response and the development of control strategies. However, the One Health concept and approach is much broader than zoonoses; it extends to including antimicrobial resistance, food safety, and environmental health and, consequently, impacts on global health security, economic wellbeing, and international trade. It is this breadth of One Health that connects the papers in this Special Issue.

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