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Hydrogels - Smart Materials for Biomedical Applications

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ISBN: 9781789858754 9781789858761 Year: Pages: 132 DOI: 10.5772/intechopen.78482 Language: English
Publisher: IntechOpen
Subject: Organic Chemistry --- Chemical Technology
Added to DOAB on : 2019-10-03 07:51:53

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Hydrogels, as three-dimensional polymer networks, are able to retain a large amount of water in their swollen state. The biomedical application of hydrogels was initially hampered by the toxicity of cross-linking agents and the limitations of hydrogel formation under physiological conditions. However, emerging knowledge in polymer chemistry and an increased understanding of biological processes have resulted in the design of versatile materials and minimally invasive therapies.The novel but challenging properties of hydrogels are attracting the attention of researchers in the biological, medical, and pharmaceutical fields. In the last few years, new methods have been developed for the preparation of hydrophilic polymers and hydrogels, which may be used in future biomedical and drug delivery applications. Such efforts include the synthesis of self-organized nanostructures based on triblock copolymers with applications in controlled drug delivery. These hydrogels could be used as carriers for drug delivery when combined with the techniques of drug imprinting and subsequent release. Engineered protein hydrogels have many potential advantages. They are excellent biomaterials and biodegradables. Furthermore, they could encapsulate drugs and be used in injectable forms to replace surgery, to repair damaged cartilage, in regenerative medicine, or in tissue engineering. Also, they have potential applications in gene therapy, although this field is relatively new.

Microencapsulation - Processes, Technologies and Industrial Applications

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ISBN: 9781838818692 9781838818708 9781838818715 Year: Pages: 140 DOI: 10.5772/intechopen.73747 Language: English
Publisher: IntechOpen
Subject: Medical technology --- Biotechnology
Added to DOAB on : 2019-10-03 07:51:53

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This book is intended to provide an overview and review of the latest developments in microencapsulation processes and technologies for various fields of applications. The general theme and purpose are to provide the reader with a current and general overview of the existing microencapsulation systems and to emphasize various methods of preparation, characterization, evaluation, and potential applications in various fields such as medicine, food, agricultural, and composites. The book targets readers, including researchers in materials science processing and/or formulation and microencapsulation science, engineers in the area of microcapsule development, and students in colleges and universities.

Novel Biomaterials for Tissue Engineering 2018

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ISBN: 9783038975434 / 9783038975441 Year: Pages: 426 DOI: 10.3390/books978-3-03897-544-1 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biotechnology --- General and Civil Engineering --- Materials
Added to DOAB on : 2019-02-05 10:26:51
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The concept of regenerating tissues, with properties and functions that mimic natural tissues, has attracted significant attention in recent years. It provides potential solutions for treating many diseases and other healthcare issues. To fully realize the potential of the approach, it is crucial to have a rational biomaterial design to create novel scaffolds, and other materials systems suitable for tissue engineering, repair and regeneration. Research advances on the topic include the design of new biomaterials and their composites, the scaffold fabrication via subtractive and additive manufacturing approaches, the development of implantable scaffolds for disease monitoring, diagnostics, and treatment, as well as the understanding of cells–biomaterial scaffolds interaction. This Special Issue, “Novel Biomaterials for Tissue Engineering”, covers a selection of timely research activities in the field of biomaterials for tissue engineering and regeneration purposes. Promising findings on different approaches to design and develop new biomaterials, biomaterial systems and methods for tissue engineering, are presented and discussed. Recent advances in biofabrication techniques for tissue engineering are additionally demonstrated. The issue comprises a series of state-of-the-art experimental works, up-to-date review articles and commentaries.

Bio-based Building Skin

Authors: --- --- ---
Book Series: Environmental Footprints and Eco-design of Products and Processes ISBN: 9789811337475 Year: Pages: 183 DOI: 10.1007/978-981-13-3747-5 Language: English
Publisher: Springer
Subject: Agriculture (General) --- Science (General) --- Architecture
Added to DOAB on : 2020-01-29 11:21:04
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This book provides a compendium of material properties, demonstrates several successful examples of bio-based materials’ application in building facades, and offers ideas for new designs and novel solutions. It features a state-of-the-art review, addresses the latest trends in material selection, assembling systems, and innovative functions of facades in detail. Selected case studies on buildings from diverse locations are subsequently presented to demonstrate the successful implementation of various biomaterial solutions, which defines unique architectural styles and building functions. The structures, morphologies and aesthetic impressions related to bio-based building facades are discussed from the perspective of art and innovation; essential factors influencing the performance of materials with respect to functionality and safety are also presented. Special emphasis is placed on assessing the performance of a given facade throughout the service life of a building, and after its end. The book not only provides an excellent source of technical and scientific information, but also contributes to public awareness by demonstrating the benefits to be gained from the proper use of bio-based materials in facades. As such, it will appeal to a broad audience including architects, engineers, designers and building contractors. ; Presents case-studies and latest trends in material selection, assembling systems, and innovative functions of facades Discusses structure morphologies and aesthetic impressions related to bio-based building facades Highlights factors influencing performance of facades, with a special focus on service life of the building

Small Scale Deformation using Advanced Nanoindentation Techniques

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ISBN: 9783038979661 / 9783038979678 Year: Pages: 168 DOI: 10.3390/books978-3-03897-967-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General)
Added to DOAB on : 2019-06-26 08:44:06
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Small scale mechanical deformations have gained a significant interest over the past few decades, driven by the advances in integrated circuits and microelectromechanical systems. One of the most powerful and versatile characterization methods is the nanoindentation technique. The capabilities of these depth-sensing instruments have been improved considerably. They can perform experiments in vacuum and at high temperatures, such as in-situ SEM and TEM nanoindenters. This allows researchers to visualize mechanical deformations and dislocations motion in real time. Time-dependent behavior of soft materials has also been studied in recent research works. This Special Issue on ""Small Scale Deformation using Advanced Nanoindentation Techniques""; will provide a forum for researchers from the academic and industrial communities to present advances in the field of small scale contact mechanics. Materials of interest include metals, glass, and ceramics. Manuscripts related to deformations of biomaterials and biological related specimens are also welcome. Topics of interest include, but are not limited to:

Tissue Engineering and Regenerative Nanomedicine

Authors: ---
ISBN: 9783039216567 / 9783039216574 Year: Pages: 126 DOI: 10.3390/books978-3-03921-657-4 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering
Added to DOAB on : 2019-12-09 11:49:16
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[This book focus on the most recent advances related to the design and processing methods of different nanobiomaterials, films, and fibers; surface functionalization strategies, including biological performance assessment and cytocompatibility; and their applications in tissue engineering strategies.]

Food Packaging. Materials and Technologies

Authors: ---
ISBN: 9783038977667 9783038977674 Year: Pages: 216 DOI: 10.3390/books978-3-03897-767-4 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Technology (General) --- General and Civil Engineering --- Materials
Added to DOAB on : 2019-04-25 16:37:17
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Because of the increasing pressure on both food safety and packaging/food waste, the topic is important both for academics, applied research, industry and also for environment protection. Different materials, such as glass, metals, paper and paperboards, and non-degradable and degradable polymers, with versatile properties, are attractive for potential uses in food packaging. Food packaging is the largest area of application within the food sector. Only the nanotechnology-enabled products in the food sector account for ~50% of the market value, with and the annual growth rate is 11.65%. Technological developments are also of great interest. In the food sector, nanotechnology is involved in packaging materials with extremely high gas barriers, antimicrobial properties, and also in nanoencapsulants for the delivery of nutrients, flavors, or aromas, antimicrobial, and antioxidant compounds. Applications of materials, including nanomaterials in packaging and food safety, are in forms of: edible films, polymer nanocomposites, as high barrier packaging materials, nanocoatings, surface biocides, silver nanoparticles as potent antimicrobial agents, nutrition and neutraceuticals, active/bioactive packaging, intelligent packaging, nanosensors and nanomaterial-based assays for the detection of food relevant analytes (gasses, small organic molecules and food-borne pathogens) and bioplastics.

Tribological Performance of Artificial Joints

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ISBN: 9783039210787 / 9783039210794 Year: Pages: 178 DOI: 10.3390/books978-3-03921-079-4 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Surgery
Added to DOAB on : 2019-08-28 11:21:27
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Joint replacement is a very successful medical treatment. However, the survivorship of the implants could be adversely affected due to the loss of materials in the form of particles or ions as the bearing surfaces articulate against earch other. The consequent tissue and immune response to the wear products, remain one of the key factors of their failure. Tribology has been defined as the science and technology of interacting surfaces in relative motion and all related wear products (e.g., particles, ions, etc.). Over the last few decades, in an attempt to understand and improve joint replacement technology, the tribological performance of several material combinations have been studied experimentally and assessed clinically. In addition, research has focused on the biological effects and long term consequences of wear products. Improvements have been made in manufacturing processes, precision engineering capabilities, device designs and materials properties in order to minimize wear and friction and maximize component longevity in vivo.

Polymeric Materials: Surfaces, Interfaces and Bioapplications

Authors: --- --- --- --- et al.
ISBN: 9783038979623 / 9783038979630 Year: Pages: 342 DOI: 10.3390/books978-3-03897-963-0 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Physics (General)
Added to DOAB on : 2019-06-26 08:44:06
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This book collects the articles published in the Special Issue “Polymeric Materials: Surfaces, Interfaces and Bioapplications”. It shows the advances in polymeric materials, which have tremendous applications in agricultural films, food packaging, dental restoration, antimicrobial systems, and tissue engineering. These polymeric materials are presented as films, coatings, particles, fibers, hydrogels, or networks. The potential to modify and modulate their surfaces or their content by different techniques, such as click chemistry, ozonation, breath figures, wrinkle formation, or electrospray, are also explained, taking into account the relationship between the structure and properties in the final application. Moreover, new trends in the development of such materials are presented, using more environmental friendly and safe methods, which, at the same time, have a high impact on our society.

Keywords

corn stalk fiber --- friction composite --- friction and wear --- worn surface morphology --- antifouling coatings --- biofouling --- natural biofilms --- single-stranded conformation polymorphism --- polydimethylsiloxane --- multidimensional scale analysis --- antimicrobial coatings --- porous surfaces --- breath figures --- antimicrobial polymer --- coatings --- hydrogel --- protein-repellent polymer --- surface-attached polymer network --- polymer cross-linking --- alginate modification --- calcium chloride --- microparticles --- spray drying --- prolonged drug release --- gradient wrinkles --- UV/ozone --- irradiance --- polymeric composites --- bonding agents --- antibacterial --- oral biofilms --- periodontal pathogens --- caries inhibition --- recycling --- polypropylene --- biodegradable polymers --- degradation --- inmiscibility --- hemicelluloses --- chitosan --- composite films --- oxygen barrier property --- food packaging --- nanosecond laser surface modification --- ABS (Acrylonitrile-Butadiene-Styrene) --- surface wettability --- superhydrophobic --- superhydrophilic --- poly(x-chlorostyrene) --- honeycomb --- breath figures --- conformational entropy --- spinal anatomy --- intervertebral disc --- degenerative disc disease --- herniated disc --- spinal fusion --- total disc replacement --- tissue engineering --- Electrically conductive polymers --- Electroactive biomaterials --- Electrical stimulation --- Smart composites --- Bioelectric effect --- Drug delivery --- Artificial muscle --- bio-based --- fossil --- hybrids --- blends --- packaging --- bio-based polymers --- antimicrobial --- biodegradable --- sustainable --- eco-friendly --- graphene oxide --- chitosan --- composites --- scaffolds --- tissue engineering --- surface modification/functionalization --- surface segregation --- micro- and nanopatterned films --- blends and (nano)composites --- coatings --- surface wettability --- stimuli-responsive materials/smart surfaces --- bioapplications

Sol-Gel Chemistry Applied to Materials Science

Author:
ISBN: 9783039213535 / 9783039213542 Year: Pages: 216 DOI: 10.3390/books978-3-03921-354-2 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Chemistry (General)
Added to DOAB on : 2019-12-09 11:49:15
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Sol–gel technology is a contemporary advancement in science that requires taking a multidisciplinary approach with regard to its various applications. This book highlights some applications of the sol–gel technology, including protective coatings, catalysts, piezoelectric devices, wave guides, lenses, high-strength ceramics, superconductors, synthesis of nanoparticles, and insulating materials. In particular, for biotechnological applications, biomolecules or the incorporation of bioactive substances into the sol–gel matrix has been extensively studied and has been a challenge for many researchers. Some sol–gel materials are widely applied in light-emitting diodes, solar cells, sensing, catalysis, integration in photovoltaic devices, and more recently in biosensing, bioimaging, or medical diagnosis; others can be considered excellent drug delivery systems. The goal of an ideal drug delivery system is the prompt delivery of a therapeutic amount of the drug to the proper site in the body, where the desired drug concentration can be maintained. The interactions between drugs and the sol–gel system can affect the release rate. In conclusion, the sol–gel synthesis method offers mixing at the molecular level and is able to improve the chemical homogeneity of the resulting composite. This opens new doors not only regarding

Keywords

sol-gel method --- Fourier transform infrared spectroscopy (FTIR) analysis --- bioactivity --- biocompatibility --- sol–gel method --- organic-inorganic hybrids --- chlorogenic acid --- cytotoxicity --- biocompatibility --- silsesquioxanes --- thiol-ene click reaction --- in situ water production --- hydrophobic coatings --- cotton fabric --- paper --- NMR --- wettability --- sol-gel --- hollow sphere --- 1D structure --- sol-gel --- thin-disk laser --- Yb-doped glasses --- aluminosilicate glasses --- photoluminescence --- ultrasonic spray deposition --- tungsten oxide --- lithium lanthanum titanium oxide --- conformal coating --- Li-ion batteries --- sol-gel technique --- biomaterials --- cell proliferation --- cell cycle --- one transistor and one resistor (1T1R) --- organic thin-film transistor (OTFT) --- resistive random access memory (RRAM) --- sol-gel --- lithium-ion battery --- LiMnxFe(1?x)PO4 --- carbon coating --- pseudo-diffusion coefficient --- potential step voltammetry --- electrochemical impedance spectroscopy --- sol-gel --- oxyfluoride glass-ceramics --- nanocrystal --- optical properties --- sol-gel method --- SiO2–based hybrids --- poly(?-caprolactone) --- TG-DSC --- TG-FTIR --- X-ray diffraction analysis --- computer-aided design (CAD) --- mechanical analysis --- finite element analysis (FEA) --- composites --- organic–inorganic hybrid materials --- biomedical applications --- metal oxides --- multi-layer --- surface plasmon resonance --- optical sensors --- computer-aided design (CAD) --- mechanical analysis --- finite element analysis (FEA) --- composites --- hybrid materials --- biomedical applications

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