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Biodegradable Metals

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ISBN: 9783038973867 9783038973874 Year: Pages: 200 DOI: 10.3390/books978-3-03897-387-4 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General) --- Chemical Engineering
Added to DOAB on : 2018-12-06 10:15:09
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The interest in biocompatible and biodegradable metals, such as magnesium, is mainly related to their potential use as structural material for orthopedic and cardiovascular applications where a temporary medical device is required. However, in the case of magnesium, in vivo experiments have clearly shown that the corrosion degradation rate of magnesium and its alloys is too high and, hence, results in producing gas cavities that can promote the danger of gas embolism, tissue separation, and premature loss of mechanical integrity. The aim of this Special Issue on Biodegradable Metals is to explore and introduce innovative strategies to overcome the current limitations of magnesium.

Recent Research in Polymerization

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ISBN: 9789535137467 9789535137474 9789535140443 Year: Pages: 216 DOI: 10.5772/intechopen.68265 Language: English
Publisher: IntechOpen
Subject: Medicine (General)
Added to DOAB on : 2019-10-03 07:51:50

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The purpose of this book is to help you concentrate on recent developments in polymerization. The chapters collected in the book are contributions by invited researchers with a long-standing experience in different research areas. I hope that the material presented here is understandable to a broad audience, not only chemists but also scientists from various disciplines. The book contains nine chapters in three sections: (1) ""General Information about Polymerization,"" (2) ""Biomaterial Content Polymer Composites,"" and (3) ""Mechanical Properties of Polymerization."" The book provides detailed and current reviews in these different areas written by experts in their respective fields. This book is expected to be useful for polymer workers and other scientists alike and contribute to the training of current and future researchers, academics, PhD degree students, as well as other scientists.

Biomaterials - Physics and Chemistry - New Edition

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ISBN: 9781789230642 9781789230659 Year: Pages: 114 DOI: 10.5772/intechopen.69128 Language: English
Publisher: IntechOpen
Subject: Medical technology --- Biotechnology
Added to DOAB on : 2019-10-03 07:51:51

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This contribution book collects five among reviews and original articles from eminent experts working in the interdisciplinary area of biomaterial synthesis and application. From their direct and recent experience, the readers can access the novel and ongoing potentialities of different synthetic and engineered biomaterials. Contributions reflect the fundamental studies, with a particular attention to the physico-chemical mechanical characterization of biomaterials, along with biocompatibility studies and potential clinical use. After an introductory chapter on the question of storage stability for biomaterial-based devices and products and for polymeric nanomedicines, a first review deals with the use and commercial sources of hydroxyapatite in tissue engineering and other biomedical applications. A study follows on optical fiber laser marking on the properties of stainless steel in implant manufacturing. Two other reviews, respectively, focused on the approaches to prevent or treat the effects of calcification that occurs in vivo on biomaterial-based implants and on the encapsulation of pancreatic islet cells for the treatment of type I diabetes will be presented. Finally, an overview on the physical bases and application in biomaterial science of the spray-drying process will close the volume. This setting will allow to achieve a general view of how classical and novel biomaterials can be applied, along with the methodologies necessary to design, develop, and characterize them, without the restrictions necessarily imposed by industrial or profit concerns. Readers will be apprised about the methodologies used to develop biomaterials possessing the physical and biological properties needed for specific medical and clinical applications.

Chitin-Chitosan - Myriad Functionalities in Science and Technology

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ISBN: 9781789234060 9781789234077 Year: Pages: 382 DOI: 10.5772/intechopen.71146 Language: English
Publisher: IntechOpen
Subject: Biotechnology
Added to DOAB on : 2019-10-03 07:51:51

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Chitin is the second most abundant biopolymer after cellulose and is a resourceful copious and cheap biomaterial discovered in 1859 owing to significant industrial and technological utility. Raw chitin-chitosan resembles keratin in its biological functions. Chitin chemistry vastly developed via innate unparalleled biological features and exceptional physicochemical characters. Chitosan endures assorted chemical/physical modifications easily at free proactive functionalities, yet intact bulk properties are achieved through processing, viz., film, membrane, composite, hybrid, nanofibre, nanoparticle, hydrogel and scaffolds. Rapidly lessen bioresources signify chitosan as an option due to renewable eco-friendliness and drive embryonic myriad applications in S&T. Controlled surface modification in its flexible framework imparts advanced functionalized applications in science and technology developments. Chitosan-matrix is advantageous over biopolymers due to inherent economic, versatile and unequivocal portfolio from bio-molecule to quantum dots which traced its great journey in modern S&T. Overall, chitosan chemistry boosted R&D in countless domains like agriculture, biochemical, medicine, pharmaceutics, nanotechnology, biotechnology, material/food science, microbiology, biomedicine, bioengineering, biochemistry, bioprocessing and environment.

Hydrogels

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ISBN: 9781789233681 9781789233698 Year: Pages: 210 DOI: 10.5772/intechopen.68817 Language: English
Publisher: IntechOpen
Subject: Organic Chemistry --- Chemical Technology
Added to DOAB on : 2019-10-03 07:51:51

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This new important book is a collection of research and review articles from different parts of the world discussing the dynamic and vibrant field of hydrogels. The articles are linking new findings and critically reviewing the fundamental concepts and principles that are making the base for innovation. Each chapter discusses the potential of hydrogels in diverse areas. These areas include tissue engineering, implants, controlled drug release, and oil reserve treatment. The book is offering an up-to-date knowledge of hydrogels to experienced as well as new researchers.

Biomineralization

Authors: --- ---
ISBN: 9789811310027 Year: Pages: 413 DOI: 10.1007/978-981-13-1002-7 Language: English
Publisher: Springer Nature
Subject: Agriculture (General) --- Biology --- Mathematics --- Medicine (General)
Added to DOAB on : 2020-02-04 11:21:26
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This open access book is the proceedings of the 14th International Symposium on Biomineralization (BIOMIN XIV) held in 2017 at Tsukuba. Over the past 45 years, biomineralization research has unveiled details of the characteristics of the nano-structure of various biominerals; the formation mechanism of this nano-structure, including the initial stage of crystallization; and the function of organic matrices in biominerals, and this knowledge has been applied to dental, medical, pharmaceutical, materials, agricultural and environmental sciences and paleontology. As such, biomineralization is an important interdisciplinary research area, and further advances are expected in both fundamental and applied research.

Wound Repair and Regeneration

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ISBN: 9783038427674 9783038427681 Year: Pages: 302 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology
Added to DOAB on : 2018-03-26 15:46:58
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Wounds are a largely unrecognized, spiraling epidemic that affect millions of people world-wide. They are complex and involve temporal and spatial involvement of many different cell types and tissue processes. Recent advances in our understanding of wound repair and regeneration, as well as the many novel and exciting approaches aimed at healing chronic/acute wounds and reducing scar formation, make this a pertinent time for a Special Issue aimed at overviewing this important field. The goal of this book is to provide a summary of the field, describe its impact, as well as introduce the recent advances in understanding the mechanisms that underpin wound healing and scar formation. The articles include in this book highlight new developments in therapeutic approaches for wound repair including the use of nanomedicine and biomaterials to deliver cells and/or drugs to promote healing. Cellular responses that underpin angiogenesis, inflammation, proliferation and remodeling, as well as advances in cytoskeletal interactions in keratinocytes and fibroblast cell functions. Wound remodeling and scar formation including the roles of growth factors, cytokines and stem cells are included.

Looking Forward to the Future of Heparin: New Sources, Developments and Applications

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ISBN: 9783038429494 9783038429500 Year: Pages: 282 DOI: 10.3390/books978-3-03842-950-0 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Chemistry (General)
Added to DOAB on : 2019-08-28 11:21:28
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This book is a printed edition of the Special Issue Looking Forward to the Future of Heparin: New Sources, Developments and Applications that was published in Molecules

Keywords

thrombin inhibition --- LMWH --- antithrombin --- heparin oligosaccharides --- ternary complex --- heparin --- hepcidin --- iron homeostasis --- anemia --- heparin-induced thrombocytopenia --- diagnosis --- functional assay --- platelets --- heparin --- heparan sulphate --- TGF-? --- bone morphogenetic protein (BMP) --- growth and differentiation factor (GDF) --- GDNF --- BMP antagonists --- noggin --- sclerostin --- gremlin --- heparin --- enoxaparin --- subarachnoid hemorrhage --- edema --- brain injury --- inflammation --- cisplatin --- low molecular weight heparin (LMWH) --- ovarian cancer --- resistance --- heparin --- glycosaminoglycans --- chondroitin sulfate --- perylene diimide dyes --- dermatan sulfate --- fluorescent probe --- Heparin Red --- assay --- dermatan sulfate --- human plasma --- heparin --- alginate --- sulfated alginate --- biomaterials --- heparin --- heparan sulfate --- serglycin --- proteoglycan --- recombinant expression --- bioreactor --- theranostics --- solid lipid nanoparticles --- iron oxide nanoparticles --- heparin coating --- intestinal lymphatic absorption --- heparin --- heparin process --- manufacturing methods --- industrial --- super paramagnetic iron oxide nanoparticles (SPION) --- hyaluronic acid (HA) --- bovine serum albumin (BSA) --- Fe3O4·DA-BSA/HA --- paclitaxel (PTX) --- magnetic resonance imaging (MRI) --- low-molecular-weight heparin --- dalteparin --- NMR --- LC-MS --- affinity chromatography --- danaparoid sodium --- low molecular weight glycosaminoglycans --- orthogonal multi-analytical methods --- sequence and compositional investigations --- component quantitative analysis --- heparin --- crude heparin --- NMR --- quantitative NMR --- PCA --- chemometric --- HSQC --- bovine heparin --- porcine heparin --- molecular weight --- size exclusion chromatography --- pharmacopeia --- Fondaparinux sodium --- extended physicochemical characterization --- qNMR --- single crystal X-ray structure --- reference standard --- iduronic acid conformation --- Arixtra® --- n/a --- n/a --- n/a

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