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Human Polyomaviruses and Papillomaviruses

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ISBN: 9783038972204 9783038972211 Year: Pages: 196 DOI: 10.3390/books978-3-03897-221-1 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology --- Oncology
Added to DOAB on : 2018-09-21 09:25:07
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The interest in human polyomaviruses (HPyV) has seen a renaissance because of new species that have been isolated and their previously unknown association with diseases. Likewise, the increasing evidence for the association of human papillomaviruses (HPV) with oropharyngeal cancer has sparked the attention of researchers and clinicians. The Special Issue “Human Polyomaviruses and Papillomaviruses” presents studies describing the nuclear egress of BK polyomavirus mediated by the viral agnoprotein and the cellular -SNAP protein. In addition, a study examines the promoter activity of two different variants of human polyomavirus 9 in different cell lines. This Special Issue offers an interesting perspective on the epidemiology of HR-HPV in different cancers and on the mechanisms by which these viruses target host cell proteins to replicate their genome, express their genes, interfere with autophagy, and induce cancer. Other topics that are highlighted include the role of co-factors, such as smoking and co-infection, novel therapeutic strategies, and surface immunoregulatory proteins, chemokines, and cytokines as possible biomarkers to determine the stage of a tumor and to predict clinical outcomes.

Socio-Cognitive and Affective Computing

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ISBN: 9783038971986 9783038971993 Year: Pages: 254 DOI: 10.3390/books978-3-03897-199-3 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Psychology --- Computer Science
Added to DOAB on : 2018-09-21 10:52:57
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Social cognition focuses on how people process, store, and apply information about other people and social situations. It focuses on the role that cognitive processes play in social interactions. On the other hand, the term cognitive computing is generally used to refer to new hardware and/or software that mimics the functioning of the human brain and helps to improve human decision-making. In this sense, it is a type of computing with the goal of discovering more accurate models of how the human brain/mind senses, reasons, and responds to stimuli.Socio-Cognitive Computing should be understood as a set of theoretical interdisciplinary frameworks, methodologies, methods and hardware/software tools to model how the human brain mediates social interactions. In addition, Affective Computing is the study and development of systems and devices that can recognize, interpret, process, and simulate human affects, a fundamental aspect of socio-cognitive neuroscience. It is an interdisciplinary field spanning computer science, electrical engineering, psychology, and cognitive science.Physiological Computing is a category of technology in which electrophysiological data recorded directly from human activity are used to interface with a computing device. This technology becomes even more relevant when computing can be integrated pervasively in everyday life environments. Thus, Socio-Cognitive and Affective Computing systems should be able to adapt their behavior according to the Physiological Computing paradigm.This book integrates proposals from researchers who use signals from the brain and/or body to infer people's intentions and psychological state in smart computing systems. The design of this kind of systems combines knowledge and methods of ubiquitous and pervasive computing, as well as physiological data measurement and processing, with those of socio-cognitive and affective computing.

Plant Microbe Interaction 2017

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ISBN: 9783038973287 9783038973294 Year: Pages: 262 DOI: 10.3390/books978-3-03897-329-4 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Biology --- Plant Sciences
Added to DOAB on : 2018-11-14 11:21:52
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ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms.[Plants interact with microbes in many different ways and on many different levels. The most obvious interaction results in plant disease, which can be a severe threat to the global food supply. Therefore, research strives to uncover the mechanisms of host plant invasion, learn about the weapons used by pathogenic microbes, and understand the defense strategies of the affected plants. On the other hand, many interactions with the plant are indeed beneficial for the plant, increasing its ability to recruit limiting nutrients from the soil, preventing the growth of more detrimental microbes, or making the plant more resistant to abiotic stresses. Plants also serve as habitats for microbes that may colonize apoplastic spaces within leaves, may live on plant surfaces, or may prosper in the immediate vicinity of plant organs (e.g., in the rhizosoil). In this book, one editorial, two review articles, and twelve original research articles highlight the newest research endeavors on plants interacting with beneficial microbes, having to cope with detrimental microbes, or hosting complete microbiomes. Together, these articles contribute to the knowledge essential for the development of strategies that will prepare our plants to withstand the increasingly harsh conditions they will be exposed to in the coming years of climate change.]

Microbial Community Modeling: Prediction of Microbial Interactions and Community Dynamics

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ISBN: 9783038429753 9783038429760 Year: Pages: VIII, 286 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemical Engineering
Added to DOAB on : 2018-07-04 13:24:50
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Investigating the microbiome is on the frontier of science. It has the potential to resolve many issues in the realms of energy, food, human health, the environment, and biotechnology. Scientists are trying to understand, in a fundamental way, how microbes influence each other and how they organize into interaction networks. These are the keys to predicting and engineering community function and properties of the microbiome. In this regard, mathematical modeling and computational analysis play an increasing role. This book is a collection of contributions from lead scientists in the field. It provides innovative approaches and fresh perspectives for modeling environmental communities and engineered microbial consortia. Reading this book will give researchers a solid look at cutting-edge science in microbial community modeling, and at the remaining challenges such modeling poses.

Recent Developments in Smart Healthcare

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ISBN: 9783038426448 9783038426455 Year: Pages: 362 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Computer Science
Added to DOAB on : 2018-01-12 11:34:38
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Medicine is undergoing a sector-wide transformation thanks to the advances in computing and networking technologies. Healthcare is changing from reactive and hospital-centered to preventive and personalized, from disease focused to well-being centered. In essence, the healthcare systems, as well as fundamental medicine research, are becoming smarter. We anticipate significant improvements in areas ranging from molecular genomics and proteomics to decision support for healthcare professionals through big data analytics, to support behavior changes through technology-enabled self-management, and social and motivational support. Furthermore, with smart technologies, healthcare delivery could also be made more efficient, higher quality, and lower cost. In this special issue, we received a total 45 submissions and accepted 19 outstanding papers that roughly span across several interesting topics on smart healthcare, including public health, health information technology (Health IT), and smart medicine.

Marine Propulsors

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ISBN: 9783038972020 9783038972037 Year: Pages: 354 DOI: 10.3390/books978-3-03897-203-7 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Environmental Technology --- Transportation
Added to DOAB on : 2018-10-10 12:11:50
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This book provides an update on the state of the art of hydrodynamic aspects of marine propellers and turbines, covering predictions using numerical and experimental methods, where the numerical methods comprise both potential flow panel methods, Navier–Stokes solvers and mixed methods. Open and ducted propellers, as well as azimuthing thrusters are represented, as well as operation in steady conditions, waves and off-design conditions.The book consists of 16 peer-reviewed scientific papers previously published in Journal of Marine Science and Engineering.

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MDPI - Multidisciplinary Digital Publishing Institute (6)


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CC by-nc-nd (6)


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english (6)


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2018 (6)