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Biology of Brain Disorders

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889453801 Year: Pages: 586 DOI: 10.3389/978-2-88945-380-1 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Neurology --- Physiology --- Medicine (General)
Added to DOAB on : 2018-11-16 17:17:57
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Abstract

Brain disorders, including neurological and neuropsychiatric conditions, represent a challenge for public health systems and society at large. The limited knowledge of their biology hampers the development of diagnostic tools and effective therapeutics. A clear understanding of the mechanisms that underlie the onset and progression of brain disorders is required in order to identify new avenues for therapeutic intervention.Overlapping genetic risk factors across different brain disorders suggest common linkages and pathophysiological mechanisms that underlie brain disorders. Methodological and technological advances are leading to new insights that go beyond traditional hypotheses. Taking account of underlying molecular, cellular and systems biology underlying brain function will play an important role in the classification of brain disorders in future.In this Research Topic, the latest advances in our understanding of biological mechanisms across different brain disorders are presented. The areas covered include developments in neurogenetics, epigenetics, plasticity, glial cell biology, neuroimmune interactions and new technologies associated with the study of brain function. Examples of how understanding of biological mechanisms are translating into research strategies that aim to advance diagnoses and treatment of brain disorders are discussed.

Embodied Cognition over the Lifespan and in Applied Settings

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889454921 Year: Pages: 293 DOI: 10.3389/978-2-88945-492-1 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Psychology
Added to DOAB on : 2019-01-23 14:53:42
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While Embodied Cognition has now been accepted as mainstream in Cognitive Science, the study of its potential contribution to understding child developemnt and ageing, as well as its potential applications, is still in its infancy. This collection of articles explores the contribution of Embodied Cognition to studying the lifespan and potential applied fields. The contributions are theoretical and empirical and offer an important framework for future research and its applications.

Ageing Population Risks

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ISBN: 9783038428244 9783038428237 Year: Pages: VI, 224 Language: englisch
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Economics
Added to DOAB on : 2018-08-09 14:53:44
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An ageing population is a major challenge for every country in the world arising from the declining fertility rate and increasing life expectancy. A longevity risk (the adverse outcome of people living longer than expected) exacerbated by declining equity returns coupled with the record low interest rate environments has significant implications for societies and manifests as a systematic risk for providers of retirement income products. The aim of this special issue is to highlight advances inquantitative modelling of risks related to ageing population problems. It is aimed at practitioners and regulators in insurance, banking and pension industries; academic researchers; and advanced graduate students in the area.

Aging and Self-Realization

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Book Series: Aging Studies ISBN: 9783839444221 9783839444221 Year: Language: English
Publisher: transcript Verlag Grant: Knowledge Unlatched - 101219
Subject: Social Sciences
Added to DOAB on : 2019-01-15 13:33:13
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Dominant cultural narratives about later life dismiss the value senior citizens hold for society. In her cultural-philosophical critique, Hanne Laceulle outlines counter narratives that acknowledge both potentials and vulnerabilities of later life. She draws on the rich philosophical tradition of thought about self-realization and explores the significance of ethical concepts essential to the process of growing old such as autonomy, authenticity and virtue. These counter narratives aim to support older individuals in their search for a meaningful age identity, while they make society recognize its senior members as valued participants and moral agents of their own lives.

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