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Electrochemical Immunosensors and Aptasensors

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ISBN: 9783038424062 9783038424079 Year: Pages: VIII, 178 DOI: 10.3390/books978-3-03842-407-9 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Chemistry (General)
Added to DOAB on : 2017-06-02 09:40:26
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The possibility to integrate biorecognition elements into electrochemical detection systems has opened the way to a new class of powerful analytical devices named electrochemical (EC) biosensors. The first EC biosensors employed enzymes as recognition elements; however this limited their application to redox enzymes and natural or artificial redox substrates or inhibitors. Broadening this to include non-electroactive analytes was later possible thanks to the development of affinity sensors in which specific interactions between biomolecules are exploited for developing highly selective and sensitive biosensors. Presently, the combination of the exceptional molecular recognition capabilities of antibodies and aptamers with the sensitivity, low cost, practicality of use and handiness of electrochemical devices is leading to an impressive development of EC immunosensors and aptasensors that are potentially suitable to detect a wide range of analytes, following a path that is moving alongside the most recent advances in proteomics. Interestingly, with continued improvements and refinements in EC immunosensors based on the use of labels, together with intrinsically electroactive, or those with the ability to interact with electroactive molecules, a new generation of label-free sensors is being developed. This Special Issue takes stock of the state of the art and identifies prospects for EC immuno- and aptasensors, both labeled and label-free. Emphasis is placed on analytical applications for the rapid detection of disease markers and for toxicological and food analyses.

Update on Oesophageal Atresia-Tracheoesophageal Fistula

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889453047 Year: Pages: 93 DOI: 10.3389/978-2-88945-304-7 Language: English
Publisher: Frontiers Media SA
Subject: Medicine (General) --- Pediatrics
Added to DOAB on : 2018-02-27 16:16:45
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Oesophageal atresia-tracheoesophageal fistula (OA-TOF) is a congenital digestive malformation. With improvements in surgical techniques and perioperative care, survival rates now exceed 90% and OA-TOF is no more just a neonatal surgical problem, and the focus has now shifted from mortality to morbidity with focus on long-term survival and quality of life issues. The primary complications experienced by these patients include gastroesophageal reflux, peptic and eosinophilic esophagitis, anastomotic stricture, esophageal dysmotility, abnormal gastric function, feeding difficulties and respiratory disorders including tracheomalacia and “cyanotic spells”. Concerns in adults include oesophageal adenocarcinoma and epidermoid carcinoma which have been recently reported. This highlights the need for careful multidisciplinary follow up not only in childhood but also after transition to adulthood. Data regarding long-term outcomes and follow-ups are limited for patients following OA-TOF repair. The determination of the risk factors for the complicated evolution following OA-TOF repair may positively impact long-term prognoses. This e-book contains review articles and position paper on all aspects of management of this condition. The material presented in the following articles is primarily based on the presentations by world experts during the recent Fourth International Conference on Oesophageal Atresia held in Sydney in 2016.

Charakterisierung und Modellierung der wässrigen Lithium-Luft Batterie

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Book Series: Schriften des Instituts für Angewandte Materialien - Werkstoffe der Elektrotechnik, Karlsruher Institut für Technologie / Institut für Angewandte Materialien - Werkstoffe der Elektrotechnik - 2365-8029 ISSN: 23658029 ISBN: 9783731506713 Year: Volume: 31 Pages: V, 174 p. DOI: 10.5445/KSP/1000069566 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:01:58
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To estimate the reachable specific energy and power of aqueous Li-air batteries, a physical based model was developed, which for the first time includes the microstructure of Li-air cells. Parameters like solid/liquid interface resistances were quantified with help of a newly developed setup. Simulations based on the developed model revealed that even conservative estimations promise an increase in the specific energy by at least a factor of two compared to present Li-ion batteries.

Verfahren zur Charakterisierung des Niederfrequenzverhaltens von Lithium-Ionen Batterien

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Book Series: Schriften des Instituts für Angewandte Materialien - Werkstoffe der Elektrotechnik, Karlsruher Institut für Technologie / Institut für Angewandte Materialien - Werkstoffe der Elektrotechnik ISSN: 23658029 ISBN: 9783731506850 Year: Volume: 32 Pages: V, 192 p. DOI: 10.5445/KSP/1000070943 Language: GERMAN
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:01:59
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In order to understand the current-voltage behaviour of a Lithium-Ion Battery, its impedance needs to be investigated in the low-frequency domain. This work deals with measurement, modelling and model validation in that low-frequency domain and introduces the Distribution-Function-of-Differential-Capacity (DDC) as a new tool for investigating capacity contributions of different particle sizes and particle types inside of a Lithium-Ion Battery.

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