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Genetic Diversity

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ISBN: 9789535129493 9789535129509 Year: Pages: 150 DOI: 10.5772/63174 Language: English
Publisher: IntechOpen
Subject: Genetics
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Genetic diversity is the entire amount of genes and genotypes in a group of organisms and is of vital importance for their adaptation to different living conditions. If, for example, all humans were identical, the extinction of the entire kind could happen very fast. Let us care and nourish differences! The goal of this book is to present some of the contemporary thoughts on understandings of the genetic diversity patterns and their altering in a changing world. The book is aimed to the ones inspired to study and contemplate genetic diversity and to the audience beyond any frames.

Melanin

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ISBN: 9789535129790 9789535129806 Year: Pages: 114 DOI: 10.5772/63257 Language: English
Publisher: IntechOpen
Subject: Microbiology
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The word melanin refers to dark natural pigments produced by the oxidative degradation of tyrosine, catalyzed by tyrosinase, and polymerized into insoluble granular substance. The main function of melanin is to protect from harmful agents, primarily UV radiation, but also from oxidation, heavy metals, etc. In this volume, chapters deal with production of melanin in human oral mucosa (Liviu et al.), the regulation of melanin action (Cecile et al.), production and potential technological application of fungal melanins (Pombiero-Sponchiado et al.) and an innovative method for measuring melanin in various samples (Zdybel et al.). In conclusion, this volume presents various biological and industrial aspects of melanin production, uses and analysis.

Enzyme Inhibitors and Activators

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ISBN: 9789535130574 9789535130581 Year: Pages: 268 DOI: 10.5772/63325 Language: English
Publisher: IntechOpen
Subject: Microbiology
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Over the recent years, medicinal chemistry has become responsible for explaining interactions of chemical molecule processes such that many scientists in the life sciences from agronomy to medicine are engaged in medicinal research. This book contains an overview focusing on the research area of enzyme inhibitor and activator, enzyme-catalyzed biotransformation, usage of microbial enzymes, enzymes associated with programmed cell death, natural products as potential enzyme inhibitors, protease inhibitors from plants in insect pest management, peptidases, and renin-angiotensin system. The book provides an overview on basic issues and some of the recent developments in medicinal science and technology. Especially, emphasis is devoted to both experimental and theoretical aspect of modern medicine. The primary target audience for the book includes students, researchers, chemists, molecular biologists, medical doctors, pharmacologists, and professionals who are interested in associated areas. The textbook is written by international scientists with expertise in biochemistry, enzymology, molecular biology, and genetics, many of which are active in biochemical and pharmacological research. I would like to acknowledge the authors for their contribution to the book. We hope that the textbook will enhance the knowledge of scientists in the complexities of some medical approaches; it will stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications of pharmacology.

New Insights into Cell Culture Technology

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ISBN: 9789535131335 9789535131342 Year: Pages: 202 DOI: 10.5772/62590 Language: English
Publisher: IntechOpen
Subject: Cytology
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The book ""New Insights into Cell Culture Technology"" focuses on many advanced methods and techniques concerned with cell culture. The contributing authors have discussed various developments in cell culture methods, the application of insect cells for the efficient production of heterologous proteins, the expansion of human mesenchymal stromal cells for different clinical applications, the remote sensing of cell culture experiments and concepts for the development of cell culture bioprocess, continuous production of retroviral pseudotype vectors, and the production of oncolytic measles virus vectors for cancer therapy. This book is an original contribution of experts from different parts of the globe, and the in-depth information will be a significant resource for students, scientists, and physicians who are directly dealing with cells.

[""Culture"" is essential for human life and also the life of a cell. - Sivakumar Gowder]

Cytoskeleton - Structure, Dynamics, Function and Disease

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ISBN: 9789535131694 9789535131700 Year: Pages: 342 DOI: 10.5772/62622 Language: English
Publisher: IntechOpen
Subject: Cytology
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The cytoskeleton is a highly dynamic intracellular platform constituted by a three-dimensional network of proteins responsible for key cellular roles as structure and shape, cell growth and development, and offering to the cell with ""motility"" that being the ability of the entire cell to move and for material to be moved within the cell in a regulated fashion (vesicle trafficking). The present edition of Cytoskeleton provides new insights into the structure-functional features, dynamics, and cytoskeleton's relationship to diseases. The authors' contribution in this book will be of substantial importance to a wide audience such as clinicians, researches, educators, and students interested in getting updated knowledge about molecular basis of cytoskeleton, such as regulation of cell vital processes by actin-binding proteins as cell morphogenesis, motility, their implications in cell signaling, as well as strategies for clinical trial and alternative therapies based in multitargeting molecules to tackle diseases, that is, cancer.

Antibacterial Agents

Author:
ISBN: 9789535131991 9789535132004 Year: Pages: 138 DOI: 10.5772/65630 Language: English
Publisher: IntechOpen
Subject: Animal Sciences --- Microbiology
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New drugs are frequently entering into the market along with the existing drugs. The antibacterial agents can be discussed in five major classes, i.e. classification based on the type of action, source, spectrum of activity, chemical structure and function. Resistance of bacteria to antibiotics is an urgent problem of the humanity, which leads us to the lack of therapy for serious bacterial infections. Development of new antibiotics has almost ceased in the last decades - even when a new antibiotic is launched, very soon the resistance of bacteria appears. Industrial textiles exposed as awnings, screens, tents; upholstery used in large public areas such as hospitals, hotels and stations; fabrics for transports; protective clothing and personal protective equipment; bed sheets and blankets; textiles left wet between processing steps; intimate apparel, underwear, socks and sportswear, disinfection of air and water for white rooms, hospitals and operating theatres, food and pharma industries, water depuration, drinkable water supplying and air conditioning systems. Many clinicians recommend alternative approaches to using antimicrobial substances. Moreover, the majority of bioagents demonstrate on antibiotics for treatment of a wide range of diseases in human sectors. However, the misuse and mishandling of drugs lead to microbial, particularly bacterial, resistance as well as result in the difficulty of treating microbial diseases. Hence, the proposed book will give more precise information on novel antibacterial compound(s).

Novel Implications of Exosomes in Diagnosis and Treatment of Cancer and Infectious Diseases

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ISBN: 9789535133353 9789535133360 Year: Pages: 192 DOI: 10.5772/65504 Language: English
Publisher: IntechOpen
Subject: Oncology
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The aim of this book is to provide an overview of the importance of exosomes in the biomedical field, which involves in novel implications of exosomes in diagnosis and treatment of cancer and infectious diseases. The book would definitely be an ideal source of scientific information of exosomes to researchers and scientists involved in biomedicine, biology, and other areas involving cancer and infectious diseases.

Gluconeogenesis

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ISBN: 9789535133230 9789535133247 Year: Pages: 84 DOI: 10.5772/63700 Language: English
Publisher: IntechOpen
Subject: Microbiology
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Gluconeogenesis, the metabolic process through which glucose or glycogen is synthesized from noncarbohydrate substrates, is critical for maintaining the plasma glucose level within a narrow range either in the fed or fasting (nutritional deprivation) state. Dysregulation of this pathway usually causes severe or even fatal outcomes. This book discusses a series of up-to-date topics about this critical process, including the fundamental biochemical reactions of glucose metabolism, the glucogenesis process in eukaryotic cells using the Dictyostelium discoideum as a model, the role of ""gut-brain-liver axis"" in the control of glucose homeostasis, and the new mathematic model for the monitoring and prediction of blood glucose. This book is written by international scientists with expertise in the study of gluconeogenesis. By presenting a clear and succinct review of the fundamentals of gluconeogenesis, it is expected to draw more attentions and stimulate more scientists to dedicate their researches in revealing the mechanism and its application of gluconeogenesis.

Vitamin C

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ISBN: 9789535134213 9789535134220 Year: Pages: 156 DOI: 10.5772/66058 Language: English
Publisher: IntechOpen
Subject: Nutrition and Food Sciences
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This book highlights recent advances on vitamin C and related topics. The chapters of this book include basic information about vitamin C function, sources and analysis, and radioprotective and antioxidant effect of vitamin C. Also, the anticarcinogenic effect of vitamin C is introduced. Furthermore, we considered the encapsulation technique used in vitamin C preparation. Finally, recent advances in vitamin C transporter are illustrated.

Nematology - Concepts, Diagnosis and Control

Authors: ---
ISBN: 9789535134152 9789535134169 Year: Pages: 192 DOI: 10.5772/66851 Language: English
Publisher: IntechOpen
Subject: Animal Sciences
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Nematology being an established discipline covers a wide range of area ranging from basic aspect to the advanced and applied aspects involving recent advances in molecular techniques. This book discusses the following topics: the role of nematodes in our life (in agriculture, ecosystem functioning, experimental biology, ecological studies, pest management programs, or biocontrol), identification of GRSPs in nematode genomes, novel way for the diagnosis of pathogenic nematodes involving various recent molecular techniques, other methodologies for successful control of termites, evolution of plant-parasitic nematodes, viability of adult filarial nematode parasites, the impact of plant-parasitic nematodes on crops, and harnessing useful rhizosphere microorganisms for nematode control. The book also encompasses on classical study, molecular study, bioinformatics in nematology, biodiversity analysis, and culturing of nematodes in laboratory condition.

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