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The word melanin refers to dark natural pigments produced by the oxidative degradation of tyrosine, catalyzed by tyrosinase, and polymerized into insoluble granular substance. The main function of melanin is to protect from harmful agents, primarily UV radiation, but also from oxidation, heavy metals, etc. In this volume, chapters deal with production of melanin in human oral mucosa (Liviu et al.), the regulation of melanin action (Cecile et al.), production and potential technological application of fungal melanins (Pombiero-Sponchiado et al.) and an innovative method for measuring melanin in various samples (Zdybel et al.). In conclusion, this volume presents various biological and industrial aspects of melanin production, uses and analysis.

Life Sciences --- Biochemistry, Genetics and Molecular Biology --- Microbiology --- Applied Microbiology

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The book ""New Insights into Cell Culture Technology"" focuses on many advanced methods and techniques concerned with cell culture. The contributing authors have discussed various developments in cell culture methods, the application of insect cells for the efficient production of heterologous proteins, the expansion of human mesenchymal stromal cells for different clinical applications, the remote sensing of cell culture experiments and concepts for the development of cell culture bioprocess, continuous production of retroviral pseudotype vectors, and the production of oncolytic measles virus vectors for cancer therapy. This book is an original contribution of experts from different parts of the globe, and the in-depth information will be a significant resource for students, scientists, and physicians who are directly dealing with cells.

[""Culture"" is essential for human life and also the life of a cell. - Sivakumar Gowder]

Life Sciences --- Biochemistry, Genetics and Molecular Biology --- Microbiology --- Cytology

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New drugs are frequently entering into the market along with the existing drugs. The antibacterial agents can be discussed in five major classes, i.e. classification based on the type of action, source, spectrum of activity, chemical structure and function. Resistance of bacteria to antibiotics is an urgent problem of the humanity, which leads us to the lack of therapy for serious bacterial infections. Development of new antibiotics has almost ceased in the last decades - even when a new antibiotic is launched, very soon the resistance of bacteria appears. Industrial textiles exposed as awnings, screens, tents; upholstery used in large public areas such as hospitals, hotels and stations; fabrics for transports; protective clothing and personal protective equipment; bed sheets and blankets; textiles left wet between processing steps; intimate apparel, underwear, socks and sportswear, disinfection of air and water for white rooms, hospitals and operating theatres, food and pharma industries, water depuration, drinkable water supplying and air conditioning systems. Many clinicians recommend alternative approaches to using antimicrobial substances. Moreover, the majority of bioagents demonstrate on antibiotics for treatment of a wide range of diseases in human sectors. However, the misuse and mishandling of drugs lead to microbial, particularly bacterial, resistance as well as result in the difficulty of treating microbial diseases. Hence, the proposed book will give more precise information on novel antibacterial compound(s).

Life Sciences --- Biochemistry, Genetics and Molecular Biology --- Microbiology --- Bacteriology

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Gluconeogenesis, the metabolic process through which glucose or glycogen is synthesized from noncarbohydrate substrates, is critical for maintaining the plasma glucose level within a narrow range either in the fed or fasting (nutritional deprivation) state. Dysregulation of this pathway usually causes severe or even fatal outcomes. This book discusses a series of up-to-date topics about this critical process, including the fundamental biochemical reactions of glucose metabolism, the glucogenesis process in eukaryotic cells using the Dictyostelium discoideum as a model, the role of ""gut-brain-liver axis"" in the control of glucose homeostasis, and the new mathematic model for the monitoring and prediction of blood glucose. This book is written by international scientists with expertise in the study of gluconeogenesis. By presenting a clear and succinct review of the fundamentals of gluconeogenesis, it is expected to draw more attentions and stimulate more scientists to dedicate their researches in revealing the mechanism and its application of gluconeogenesis.

Life Sciences --- Biochemistry, Genetics and Molecular Biology --- Microbiology --- Microbial Physiology

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Nematology being an established discipline covers a wide range of area ranging from basic aspect to the advanced and applied aspects involving recent advances in molecular techniques. This book discusses the following topics: the role of nematodes in our life (in agriculture, ecosystem functioning, experimental biology, ecological studies, pest management programs, or biocontrol), identification of GRSPs in nematode genomes, novel way for the diagnosis of pathogenic nematodes involving various recent molecular techniques, other methodologies for successful control of termites, evolution of plant-parasitic nematodes, viability of adult filarial nematode parasites, the impact of plant-parasitic nematodes on crops, and harnessing useful rhizosphere microorganisms for nematode control. The book also encompasses on classical study, molecular study, bioinformatics in nematology, biodiversity analysis, and culturing of nematodes in laboratory condition.

Life Sciences --- Biochemistry, Genetics and Molecular Biology --- Microbiology --- Nematology