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Role of Neutrophils in Disease Pathogenesis

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ISBN: 9789535131953 9789535131960 Year: Pages: 180 DOI: 10.5772/65581 Language: English
Publisher: IntechOpen
Subject: Internal medicine
Added to DOAB on : 2019-10-03 07:51:50

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This book highlights the important role of neutrophils in health as well as in the pathogenesis of various diseases. Section 1 provides a general background information regarding the mechanisms and various triggers of neutrophil extracellular traps (NETs) formation and their role in various infectious and noninfectious diseases (such as postinjury inflammation). Section 2 provides recent evidence regarding the role of neutrophils in the pathogenesis as well as a therapeutic target for selected disease conditions such as periodontal diseases, rheumatoid arthritis, and cystic fibrosis. Section 3 describes the anti-inflammatory properties of neutrophils with focus regarding their role in graft versus host disease. This book provides a wider picture with regard to the importance of this immune cell type in various diseases with focus on one of its recently discovered properties, NETs. Therapeutic targets aimed to modulate neutrophil functions might provide novel approaches in the treatment of various diseases of infectious and noninfectious origin.

Hemorrhagic Stroke - An Update

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ISBN: 9789535135210 9789535135227 Year: Pages: 80 DOI: 10.5772/63253 Language: English
Publisher: IntechOpen
Subject: Internal medicine
Added to DOAB on : 2019-10-03 07:51:50

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The present book Hemorrhagic Stroke - An Update includes the updated information for professionals who are involved in the management of spontaneous intracerebral hemorrhage. This book contains detailed information about the pathophysiology of spontaneous intracerebral hemorrhage, neuroimaging approach in intracerebral hemorrhage, how to go about surgical intervention decision-making in these patients, and the rehabilitation issues in acute care and in long-term survivors. I hope that the collective contribution from the experts will make this book a valuable guide to further develop their understanding about spontaneous intracerebral hemorrhage. I am grateful to all the authors who have contributed their tremendous expertise to the present book and to my wife and daughter for their passionate support, and last but not least, I wish to acknowledge the outstanding support of Ms. Romina Skomersic, Publishing Process Manager, InTech Open Science, Croatia, who collaborated tirelessly in crafting this book.

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