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Enzymes from Extreme Environments

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889198306 Year: Pages: 103 DOI: 10.3389/978-2-88919-830-6 Language: English
Publisher: Frontiers Media SA
Subject: Biotechnology --- General and Civil Engineering
Added to DOAB on : 2016-01-19 14:05:46
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Enzymes are nature’s biocatalysts empowered with high catalytic power and remarkable substrate specificity. Enzymes perform a wide range of functions throughout nature, and guide the biochemistry of life with great precision. The majority of enzymes perform under conditions considered normal for mesophilic, neutrophilic, terrestrial microorganisms. However, the Earth’s biosphere contains several regions that are extreme in comparison, such as hypersaline lakes and pools, hydrothermal vents, cold oceans, dry deserts and areas exposed to intensive radiation. These areas are inhabited by a large number of extremophilic microorganisms which produce enzymes capable of functioning in unusual conditions. There is an increasing biotechnological and industrial demand for enzymes stable and functioning in harsh conditions, and over the past decade screening for, isolation and production of enzymes with unique and extreme properties has become one of the foremost areas of biotechnology research. The development of advanced molecular biology tools has facilitated the quest for production of enzymes with optimized and extreme features. These tools include large-scale screening for potential genes using metagenomics, engineering of enzymes using computational techniques and site-directed mutagenesis and molecular evolution techniques. The goal of this Research Topic is to present reports on latest advances in enzymes from all types of extreme environments. Contributions dealing with isolation of enzymes from extremophilic microorganisms or directly from natural environments, screening for and expression of enzymes with extreme properties using metagenomic approaches are welcome. In addition, contributions dealing with all forms of biocatalyst production and improvement are welcome, such as fermentation technology, protein engineering, directed evolution, rational design, and immobilization techniques.

The Plight of Older Workers: Labor Market Experience after Plant Closure in the Swiss Manufacturing Sector

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Book Series: Life Course Research and Social Policies ISSN: 2211-7776 ISBN: 9783319397528 9783319397542 Year: Pages: 195 DOI: 10.1007/978-3-319-39754-2 Language: English
Publisher: Springer Nature
Subject: Economics --- Social Sciences
Added to DOAB on : 2017-02-14 10:13:43
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This open access book examines the economic, social, and psychological consequences of manufacturing plant closure at the individual level. Using an original data set of over 1,200 workers from Switzerland who lost their manufacturing jobs after the financial crisis of 2008, the author analyzes the determinants of reemployment, the sector of reemployment, and the change in wages over a two year period. In addition, coverage also explores how plant closure affects the social relationship between a displaced worker and his or her significant other, which includes a discussion of the coping strategies on the household level as well as how changes in a worker's social and occupational life affects overall satisfaction. Readers will discover that the burden of structural change disproportionately falls on the shoulders of workers aged 55 and older who often face substantial barriers when trying to return to employment. A larger portion of this group experience long-term unemployment and those who do manage to find a new job often suffer disproportionate wage loss.This result is intriguing in the context of the current demographic change and contradicts the common assumption that young and low-qualified individuals are at greatest risk of unemployment. Advanced age—and not low education—appears to be the primary obstacle to workers finding job satisfaction after being laid off because of market conditions.

Innovations in Derivatives Markets: Fixed Income Modeling, Valuation Adjustments, Risk Management, and Regulation

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Book Series: Springer Proceedings in Mathematics & Statistics ISSN: 2194-1009 ISBN: 9783319334455 9783319334462 Year: Volume: 165 Pages: 449 DOI: 10.1007/978-3-319-33446-2 Language: English
Publisher: Springer Nature
Subject: Mechanical Engineering --- Therapeutics --- Biotechnology --- Business and Management --- Chemical Technology
Added to DOAB on : 2017-03-08 12:08:06
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This book presents 20 peer-reviewed chapters on current aspects of derivatives markets and derivative pricing. The contributions, written by leading researchers in the field as well as experienced authors from the financial industry, present the state of the art in:• Modeling counterparty credit risk: credit valuation adjustment, debit valuation adjustment, funding valuation adjustment, and wrong way risk.• Pricing and hedging in fixed-income markets and multi-curve interest-rate modeling.• Recent developments concerning contingent convertible bonds, the measuring of basis spreads, and the modeling of implied correlations.The recent financial crisis has cast tremendous doubts on the classical view on derivative pricing. Now, counterparty credit risk and liquidity issues are integral aspects of a prudent valuation procedure and the reference interest rates are represented by a multitude of curves according to their different periods and maturities.A panel discussion included in the book (featuring Damiano Brigo, Christian Fries, John Hull, and Daniel Sommer) on the foundations of modeling and pricing in the presence of counterparty credit risk provides intriguing insights on the debate.

Entwicklung und Wandel in der Gesundheitspolitik

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Book Series: Allokation im marktwirtschaftlichen System ISBN: 9783631696507 Year: Pages: 190 DOI: 10.3726/978-3-631-69650-7 Language: German
Publisher: Peter Lang International Academic Publishing Group
Subject: Economics
Added to DOAB on : 2020-10-03 00:05:33
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Vom Verteilen zum Gestalten

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Book Series: Forschung aus der Hans-Böckler-Stiftung ISBN: 9783839434093 Year: Pages: 380 DOI: 10.14361/9783839434093 Language: German
Publisher: transcript Verlag
Subject: Sociology
Added to DOAB on : 2019-01-15 13:34:28
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Worker's councils between protectionist policies and policies of social transformation: a history of the industrial consultation processes in the West-German automobile industry after the Second World War.

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