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The Metaphorical Brain

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889197729 Year: Pages: 178 DOI: 10.3389/978-2-88919-772-9 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Science (General)
Added to DOAB on : 2016-04-07 11:22:02
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Metaphor has been an issue of intense research and debate for decades (see, for example [1]). Researchers in various disciplines, including linguistics, psychology, computer science, education, and philosophy have developed a variety of theories, and much progress has been made [2]. For one, metaphor is no longer considered a rhetorical flourish that is found mainly in literary texts. Rather, linguists have shown that metaphor is a pervasive phenomenon in everyday language, a major force in the development of new word meanings, and the source of at least some grammatical function words [3]. Indeed, one of the most influential theories of metaphor involves the suggestion that the frequency of metaphoric language results because cross-domain mappings are a major determinant in the organization of semantic memory, as cognitive and neural resources for dealing with concrete domains are recruited for the conceptualization of more abstract ones [4]. Researchers in cognitive neuroscience have explored whether particular kinds of brain damage are associated with metaphor production and comprehension deficits, and whether similar brain regions are recruited when healthy adults understand the literal and metaphorical meanings of the same words (see [5] for a review). Whereas early research on this topic focused on the issue of the role of hemispheric asymmetry in the comprehension and production of metaphors [6], in recent years cognitive neuroscientists have argued that metaphor is not a monolithic category, and that metaphor processing varies as a function of numerous factors, including the novelty or conventionality of a particular metaphoric expression, its part of speech, and the extent of contextual support for the metaphoric meaning (see, e.g., [7], [8], [9]). Moreover, recent developments in cognitive neuroscience point to a sensorimotor basis for many concrete concepts, and raise the issue of whether these mechanisms are ever recruited to process more abstract concepts [10]. This Frontiers Research Topic brings together contributions from researchers in cognitive neuroscience whose work involves the study of metaphor in language and thought in order to promote the development of the neuroscientific investigation of metaphor. Adopting an interdisciplinary perspective, it synthesizes current findings on the cognitive neuroscience of metaphor, provides a forum for voicing novel perspectives, and promotes avenues for new research on the metaphorical brain.

Advances in Virtual Agents and Affective Computing for the Understanding and Remediation of Social Cognitive Disorders

Authors: --- --- --- --- et al.
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889197873 Year: Pages: 138 DOI: 10.3389/978-2-88919-787-3 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Science (General)
Added to DOAB on : 2016-04-07 11:22:02
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Advances in modern sciences occur thanks to within-fields discoveries as well as confrontation of concepts and methods from separated, sometimes distant, domains of knowledge. For instance, the fields of psychology and psychopathology benefited from accumulated contributions from cognitive neurosciences, which, in turn, received insights from molecular chemistry, cellular biology, physics (neuroimaging), statistics and computer sciences (data processing), etc. From the results of these researches, one can argue that among the numerous cognitive phenomena supposedly involved in the emergence the human intelligence and organized behavior, some of them are specific to the social nature of our phylogenetic order. Scientific reductionism allowed to divide the social cognitive system into several components, i.e. emotion processing and regulation, mental state inference (theory of mind), agency, etc. New paradigms were progressively designed to investigate these processes within highly-controlled laboratory settings. Moreover, the related constructs were successful at better understanding psychopathological conditions such as autism and schizophrenia, with partial relationships with illness outcomes.

Omega-3 Fatty Acids in Health and Disease

ISBN: 9783038422723 9783038422730 Year: Pages: XII, 312 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General)
Added to DOAB on : 2016-11-11 19:02:10
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The role of major dietary omega-3 fatty acids (Ω-3; α-linolenic acid, eicosapentaenoic acid and docosahexaenoic acid) in human health has generated enormous scientific interest and many controversies in recent years. Due to a growing number of studies with conflicting or even negative clinical results, the former “hype” of Ω-3 thought to be beneficial in many aspects of human health regardless of the physiological and clinical preconditions is now being critically re-evaluated, especially with respect to the potential role of Ω-3 fatty acid supplementation in preventing a variety of diseases and clinical conditions. This critical view reflects the complex interaction of Ω-3 with cell membranes and their integrated proteins mediating signal transduction, transport systems, and other processes. Moreover, Ω-3 are precursors of bioactive metabolites, such as eicosanoids, lipoxins, resolvins, protectins, maresins, and nitrolipids that influence several physiological and pathophysiological processes and their full spectrum of effects are only beginning to be defined. Finally, physiological and pathophysiological conditions as well as concomitant pharmacological treatments may influence the specific and non-specific actions of Ω-3 supplementation.This Special Issue of the Journal of Clinical Medicine will emphasize the role and biological interactions of Ω-3 with regard to cancer, psychiatric disorders, metabolic disorders and nutrition and will also reflect on some basic molecular and cellular mechanisms.

Entgrenzungen des Wahnsinns. Psychopathie und Psychopathologisierungen um 1900

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Book Series: Schriften des Historischen Kollegs ISSN: 2190-1392 ISBN: 9783110443493 Year: Volume: 93 Pages: 315,00 DOI: 10.1515/9783110443493 Language: German
Publisher: De Gruyter
Subject: History
Added to DOAB on : 2019-06-27 13:08:38

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The rise of psychiatry in the second half of the 19th century was accompanied by a number of dislocations. Modern artistic tendencies, deviant sexual behavior, and other maladaptive social behavior patterns were psycho-pathologized, and the notion of insanity took on new connotations. The book discusses these diverse phenomena in an original and insightful way with reference to institutional, conceptual, and case examples.

Reward Processing in Motivational and Affective Disorders

Authors: ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889199860 Year: Pages: 117 DOI: 10.3389/978-2-88919-986-0 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Psychology
Added to DOAB on : 2016-01-19 14:05:46
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Preferential reward processing is the hallmark of addiction, where salient cues become overvalued and trigger compulsion. In depression, rewards appear to lose their incentive properties or become devalued. In the context of schizophrenia, aberrations in neural reward signalling are thought to contribute to the overvaluation of irrelevant stimuli on the one hand and the onset of negative symptoms on the other. Accordingly, reward processing has emerged as a key variable in contemporary, evidence based, diagnostic frameworks, such as the Research Domain Criteria launched by the United States National Institute of Mental Health. Delineation of the underlying mechanisms of aberrant or blunted reward processing can be of trans-diagnostic importance across several neuropsychiatric disorders. Reward processing can become automatic thus raising the question of cognitive control, a core theme of this Topic, which aims at justifying the necessity of reward processing as a potential therapeutic target in clinical settings. Empirical and theoretical contributions on the following themes were expected to: *Explore new avenues of research by investigating the processing of rewards at the cognitive, behavioral, motivational, neural systems and individual difference levels. A developmental focus is promising in this regard, probing the core processes that shape reward processing and thus subsequent liability to motivational and affective disorders. *Develop and refine conceptual models of reward processing from computational neuroscience. *Promote greater understanding and development of emergent therapeutic approaches such as cognitive bias modification and behavioural approach or avoidance training. A key question is the feasibility of reversing or modifying maladaptive patterns of reward processing to therapeutic ends. *Refine and augment the evidential database for tried and tested therapies such as Contingency Management and Behavioral Activation by focusing on core cognitive processes mediating rewards. *Provide a potential dimensional approach for reward processing deficits that can be of trans-diagnostic importance in clinically relevant disorders, including depression and addiction * Investigate the subjective experience of pleasure- the hedonic aspect of reward seeking and consumption – and how this can be distinguished from the motivational, sometimes compulsive, component of reward pursuit. This promises more nuanced and effective interventions. Depression, for instance, could be seen as the restricted pursuit of pleasure rather than blunted pleasure experience; addiction can be viewed as accentuated drug seeking despite diminished consummatory pleasure. This aims to place motivation centre stage in both scenarios, emphasising the transdiagnostic theme of the Topic. *Temporal discounting of future rewards, whereby smaller, more immediate rewards are chosen even when significantly more valuable deferred rewards are available, is another trans-diagnostic phenomenon of interest in the in the present context. Factors that influence this, such as discounting of future reward are thought to reflect compulsion in the addictive context and hopelessness on the part of people experiencing depression. The executive cognitive processes that regulate this decision making are of both scientific and clinical significance. Empirical findings, theoretical contributions or commentaries bearing on cognitive or executive control were therefore welcome.

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