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Human Papillomavirus - Research in a Global Perspective

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ISBN: 9789535124399 9789535124405 9789535141976 Year: Pages: 318 DOI: 10.5772/61697 Language: English
Publisher: IntechOpen
Subject: Oncology
Added to DOAB on : 2019-10-03 07:51:49

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This book is a feast of knowledge, yet a balanced diet of healthy foods. There are high values of rich essential nutrients from top-quality medical research. But they are made easily digestible and absorbable, even by health care providers and planners, working in resource-limited settings, in all parts of the world, through social implications and community applications. All the chapters are value-added master pieces. The book would serve both as a scientific reference guide and a practical work manual. The authors, editor, and Intech publishers, together, are pleased to provide the readers a precious blend of scientific excellence and social relevance, for health empowerment, globally. We wish the readers great success, savoring science and sociology together.

Human Skin Cancer, Potential Biomarkers and Therapeutic Targets

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ISBN: 9789535127109 9789535127116 Year: Pages: 150 DOI: 10.5772/61922 Language: English
Publisher: IntechOpen
Subject: Oncology
Added to DOAB on : 2019-10-03 07:51:49

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Skin cancers, basal and squamous cell carcinomas, malignant melanomas, and Merkel cell carcinomas, constitute arguably the most common and increasingly prevalent human neoplasms. Here we discuss the epigenetic changes in DNA and chromatin, which are increasingly associated with melanoma. Several chapters focus on the posttranscriptional modification of the proteins at the melanocyte cell surface, their role in tumorigenesis, and their potential as therapeutic targets. Specifically, extracellular modifications of integrins, glycosylation of cell surface proteins, and changes of cadherins are presented. In a very interesting approach, a potential to target the mitochondria of melanoma cells is investigated. In conclusion, this volume presents various aspects of human skin cancers, components of the large worldwide effort to combat and eradicate this growing health concern.

Das Blaue Buch: Chemotherapie-Manual Hämatologie und Onkologie

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ISBN: 9783662514191 9783662514207 Year: Pages: 594 DOI: 10.1007/978-3-662-51420-7 Language: German
Publisher: Springer
Subject: Pharmacy and materia medica --- Nursing --- Oncology
Added to DOAB on : 2016-12-20 12:36:27
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Einfach handhabbare und praxisorientierte Sammlung von Chemotherapie-Protokollen zur Behandlung von Tumorpatienten mit soliden und hämatologischen Erkrankungen. Wie gewohnt sind auf einen Blick Detailinformationen zu Chemotherapie, Begleitmedikation, Notfallsituationen, Nebenwirkungen, Kontrollen und supportiven Therapien sowie Zusatzinformationen für eine sichere Applikation zu finden.Das Buch richtet sich an behandelnde Ärzte, Pflegende, Apotheker und alle Tumortherapie-Interessierte.

Biology-Driven Targeted Therapy of Pediatric Soft-Tissue and Bone Tumors: Current Opportunities and Future Challenges

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889198191 Year: Pages: 147 DOI: 10.3389/978-2-88919-819-1 Language: English
Publisher: Frontiers Media SA
Subject: Oncology --- Medicine (General)
Added to DOAB on : 2016-01-19 14:05:46
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Recent advances in the understanding of the biological basis of pediatric soft-tissue and bone tumors, especially owing to the advent of “omics” technologies, have led to an exponential increase in the current knowledge on the genetic and cellular patho-mechanisms that drive these diseases. This offers the unprecedented opportunity to develop and implement targeted therapies such as monoclonal antibodies, small molecules, oncolytic viruses, and immunotherapies in standard and/or personalized treatment regimens. However, to date only a few examples document a successful translation of discoveries from the bench to the bedside. Recent international expert congresses such as the “Pediatric Cancer Translational Genomics” conference (Phoenix, Arizona, 2012), the ESF-EMBO workshop on “Molecular Biology and Innovative Therapies in Sarcomas” (Pultusk, Poland, 2012), and the AACR special meeting on “Pediatric Cancer at the Crossroads – Translating Discovery into Improved Outcomes” (San Diego, California, 2013) further emphasize the urgent need for a more rapid and especially more successful translational process. Hence, we strongly believe that a Frontiers Research Topic aiming at this aspect would fit just in time and that it would have great potential to receive numerous contributions of outstanding experts of the field. The proposed Frontiers Research Topic shall provide a platform for active and interdisciplinary discussion, summarize current state-of-the-art knowledge on all basic research and translational aspects in pediatric soft-tissue and bone tumors, and offer new perspectives of how to further promote and accelerate the translational process. We welcome high-quality original research articles, brief reports, as well as opinion, hypothesis, and review articles, and especially encourage submissions from early-career scientists.

Psychosocial Advances in Neuro-Oncology

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889197828 Year: Pages: 142 DOI: 10.3389/978-2-88919-782-8 Language: English
Publisher: Frontiers Media SA
Subject: Oncology --- Medicine (General)
Added to DOAB on : 2016-04-07 11:22:02
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Neuro-oncology is a rapidly growing field concerned with scientific developments and clinical applications related to neuroscience, neuropsychology, cancer and oncology. Neuro-oncological disorders include cancers that directly affect the central nervous system (CNS), such as brain tumours and brain metastases, and non-CNS cancers with treatments that produce neurocognitive impairment. To date, the biological mechanisms and neuropsychological effects of brain tumour and cancer have been the dominant focus in neuro-oncology literature. In terms of psychosocial aspects of care, people’s understanding of their diagnosis and symptoms and how they cope with their illness has a major influence on their emotional well-being and quality of life.The development and evaluation of psychological and supportive care interventions for people with brain tumour is an area of emerging research and of high interest to health professionals working in the field. This Research Topic aims to enhance understanding of the psychological and social consequences of brain tumour and other cancers impacting neurocognitive function. It also aims to showcase new developments in assessment and psychosocial intervention approaches.

Cardiovascular Toxicities of Breast Cancer Treatment: Emerging Issues in Cardio-Oncology

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889195695 Year: Pages: 83 DOI: 10.3389/978-2-88919-569-5 Language: English
Publisher: Frontiers Media SA
Subject: Oncology --- Medicine (General)
Added to DOAB on : 2017-02-03 17:04:57
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Cancer and cardiovascular disease (CVD) are the two most common causes of mortality and morbidity worldwide. The incidence of both cancer and cardiovascular disease increases with age. With increased life expectancy, the burden of both these diseases will increase substantially in coming years. Patients with CVD share multiple common risk factors and lifestyle behaviors in addition to frequently suffering from multiple comorbid conditions. Tobacco use, hypertension, high cholesterol, diabetes, physical inactivity, and poor nutrition are all established risk factors of heart disease. Patients with diseases such as breast cancer may develop CVD from treatment, such as use of chemotherapy and RT. Effects on the heart are a potentially significant and serious clinical problem in radiation therapy treatment of breast cancer. Over the course of the past 50 years, there have been great advances in the delivery of RT due to the development of new techniques, beam energy, improvement in imaging modalities, and development of image registration strategies. It is hypothesized that cardiac damage from RT is correlated to the dose absorbed by the heart and differs between left- and right-breast radiotherapy. The damage to cardiac micro- and macro-vasculature is the pathophysiological cause of RT-related heart disease. Given the growing clinical relevance of cardio-oncology, this Frontiers in Oncology Research Topic provides a venue for disseminating focused reviews and cutting edge research in this quickly growing field. We encourage submission of original papers and reviews dealing with cardiac toxicity after breast cancer treatment, motion management to reduce cardiac exposure, imaging to evaluate potential cardiac toxicities and primary prevention of cardiac disease in the breast cancer patient.

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2016 (6)